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GFS Chemicals, Inc. Innovation and Commercialization through Chemistry Leaders in the development and commercialization of specialty alkynes and derivatives ISO 9001:2008 Certified Product Offering • GFS Chemicals remains focused on a core set of synthetic methodologies • In support of alkyne production, we offer down stream intermediates such as olefins, heteroaromatics and heterocycles • We offer over 2000 organic chemicals in our product base Core Synthetic Chemistry Na & Li/Liquid Ammonia Chemistry – – – – Alkylations Aminations Reductions (Birch, trans) Ethynylations Halogenations – Brominations – Chlorinations – Iodinations Core Synthetic Chemistry Alkyne Chemistry – – – – – – Eliminations Ethynylations Sonogashira Glaser Coupling Cadiot-Chodkiewicz Click Chemistry Core Synthetic Chemistry • Organometallic Chemistry – Grignard – Alkyl lithium – Coupling (Suzuki, Stille, Negishi, Kumada) – Heck Reaction – LI/NA Amide – Cis-reductions Core Synthetic Structures • Alkynes – – – – – – – Aromatic Terminal Internal Alcohols Ketones Acids Conjugated • Olefins – – – – – – – Cis/trans En-yne Cyclic Grignards Vinyl Aryl Alkyl Core Synthetic Structures • Halogenated Organics • Heteroaromatic – – – – Alkynes Olefins Alkyl Aromatic – – – – – – Quinolines Indoles Pyrimidines Bipyridines Phenanthrolines Terpyridines Safety and Environment • GFS is a Tier II Chem Stewards organization focused on safety improvement practices and waste minimization, recovery policies and controls • Selected Employees are DOT, IATA and IMO certified to support all modes of material logistics to ensure safe and legal shipments world wide. Safety and Environment • GFS is a Tier II Chem Stewards organization focused on safety improvement practices and waste minimization, recovery policies and controls • Selected Employees are DOT, IATA and IMO certified to support all modes of material logistics to ensure safe and legal shipments world wide. Compliance and Quality • GFS organic production operations are a zero discharge facility compliant with all local and federal EPA regulations • We adhere to ISO 9001:2008 standards for quality practices and have been ISO certified since 1997 International Operations • Sourcing Operations in Beijing China • Serving over 80 countries worldwide • www.GFSInternational.com – Japanese – German – French – Spanish Contact: David Baust– General Manager Specialty Organic Division [email protected] Office: 614-224-5013 extension 103 Cell: 614-975-6304 www.gfsorganics.com