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Fall 2010
Patient-Centered Cancer Care
A New Era Begins
OU MEDICINE
CONTENTS
OU Medicine
Dean’s Message
Dear Alumni and Friends,
OU MEDICINE
The OU Cancer Institute is one of the most important medical and
health care projects ever undertaken by the University of Oklahoma,
the College of Medicine and the state of Oklahoma. It is a testimony
to the power of the public-private partnerships we have worked hard
to create. Construction of the new facility is now at a stage where we
can begin to appreciate its physical impact on the OU Health Sciences
Center campus. The new building is scheduled for completion in 2011.
Special events, including a building dedication, are being planned for
the public, including bus tours to the center from towns across the
state. In anticipation of the opening, this issue of OU Medicine features
numerous articles highlighting aspects of the comprehensive cancer
center and programs that will serve Oklahoma and the region.
M. Dewayne Andrews, M.D., MACP
The OU Cancer Institute provides additional impetus to all three
missions of the College of Medicine – education, biomedical research and patient care. Care for patients
with cancer is being significantly reorganized, bringing new and innovative interdisciplinary approaches
and programs to patients, and providing them with the latest advances in cancer care coupled with
extraordinary commitment to the patients’ needs and the needs of their family members. The building
itself has been designed with special recognition of these important needs. President and Mrs. Boren
together also have given special time and attention to assisting with the cancer center building, knowing how the environment for care importantly affects both patients and families.
OU First Lady Molly Shi Boren has been assisting the OU Cancer Institute in drawing the best practices from around the country to create an inviting atmosphere for all those who enter the building. The
comfortable and healing environment that will be created with beautiful surroundings will be a model
for emulation. A major focal point of the facility will be the “healing garden,” a beautiful outdoor space
30 feet below street level with flowers, fountains, a water wall and tables for families and friends.
Cancer research – basic, translational, and clinical – has accelerated here as progress has been made
in developing the new cancer center. We are particularly pleased about the new Phase I clinical trials.
We will continue to recruit new scientists and physician-investigators as we expand into additional areas.
Education and training are also key goals of the OU Cancer Institute. It is our responsibility to educate
and train the next generation of cancer physicians and researchers and the other health care workers
who will serve cancer patients. This new center provides outstanding opportunities.
I could not close my comments without giving special recognition and appreciation to the many
generous donors who share our vision of what this comprehensive cancer center can mean for providing patients in this region of the country with an exceptional place for cancer care and for advancing
both the understanding of and treatments for cancer. Our vision is about to become reality.
Sincerely,
M. Dewayne Andrews, M.D., MACP
Vice President for Health Affairs
Executive Dean, College of Medicine
University of Oklahoma
College of Medicine
Senior Vice President and Provost
OU Health Sciences Center
Joseph J. Ferretti, Ph.D.
Vice President for Health Affairs
Executive Dean, College of Medicine
M. Dewayne Andrews, M.D.
Writer/Editor
Judy Kelley
Contributing Writer
Jerri Culpepper
Design
Liz Fabry
Third Degree Advertising
Photography
David McNeese
McNeese Fitzgerald & Associates
Terry Stover
OUHSC Photographic Services
OU Medicine is published twice a year by
the OU College of Medicine. For further
information or to submit news for the Class
Notes section, contact:
Judy Kelley - Editor
[email protected]
975 N.E. 10th St., BRC 238
Oklahoma City, OK 73104
Phone: (405) 271-2850
Fax: (405) 271-2351
OU Medicine is online at www.medicine.ouhsc.edu
The University of Oklahoma is an equal opportunity institution. Copies of this magazine were printed at no cost to
the taxpayers of the State of Oklahoma.
© 2010 University of Oklahoma
TABLE OF CONTENTS
2 Vital Signs
10 New Era in Cancer Care Begins
Oklahoma’s only comprehensive academic cancer center will meet the medical,
emotional and practical needs of patients and their families when it opens in
late spring or early summer.
16 What Is Patient-Centered Multidisciplinary Care?
OU Cancer Institute patients will experience care that centers on their needs
and their schedules. Greg Krempl, M.D., explains what this means to his head
and neck cancer patients.
18 Life and Limb
New surgical techniques are saving the lives and preserving the limbs of
Oklahoma bone cancer patients.
20 Marrow and More
The OU Cancer Institute is home to the state’s only comprehensive bone
marrow and peripheral blood stem cell transplant program.
22 A Fighting Chance
The OU Cancer Institute’s clinical trial program offers Oklahoma cancer patients
the opportunity to fight their disease with the latest experimental therapies
available.
25 Pioneering Change
Through clinical trials, the OU Cancer Institute’s gynecologic oncology program
and its patients are changing the way women’s cancer is treated.
26 It’s Personal
When his mother died of oropharyngeal cancer, the search for a cure became
personal for the director of basic science research in the OU Cancer Institute.
30 Patterns May Lead to Detection
Molecules present in the blood of people with lung and pancreatic cancer may
lead to early detection of two deadly diseases that are too often found too late.
32 A Marathon, Not a Sprint
The development of a successful new drug can take two decades of dead-ends,
delays and disappointments.
33 A T-Cell Vaccine for Breast Cancer?
Scientist William Hildebrand is developing a vaccine to trigger a T-cell assault on
breast cancer cells.
34 True Believer
Belief that stem cells can be blamed for tumor development and metastasis:
religion or science?
COVER PHOTO:
It’s been nearly two years since Julie Linse,
pictured, was told her pancreatic cancer was
inoperable because the tumor was wrapped
around an artery. Willing to try a relatively new
procedure offered by her team of physicians,
Linse underwent chemotherapy to shrink the
tumor enough for OU surgeon Russell Postier,
M.D., to remove it safely. A combination of
chemotherapy and radiation therapy followed,
with an additional round of chemotherapy after that. Putting patients at the center of their
care is a hallmark of the OU Cancer Institute,
shown in the background.
37 Oklahoma Students Care
Students across Oklahoma raise money and advocate healthy lifestyles with
help from First Lady Kim Henry and a trio of Heisman Trophy winners.
40 Where the Class of 2010 Is Now
The results of Match Day are listed.
45 OU School of Community Medicine
A planned health information network linking 11 counties receives a
$12 million stimulus grant; ground is broken for Wayman Tisdale Specialty
Health Center; John Tipton, M.D., named chair of family medicine.
48 Faculty News
50 Class Notes
54 Alumni News
Evening of Excellence set Jan. 27, 2011; Medicine fundraisers named;
Alumni Day held.
V I TA L S I G N S
Hamm Center Gives
Four Talley Grants
Four junior researchers at the Harold Hamm
Oklahoma Diabetes Center have received 2010 Talley
Research Awards for their work in diabetes.
The awards were made possible by Britani Talley Bowman in honor of her father, Hobart native and University
of Oklahoma alumnus William “Bill” W. Talley II, Ph.D.
Each award provides $45,000 to help make a project competitive for funding at the national level within 18 months.
“Awards such as the Talley Award are extremely
important for starting the career of a promising junior
researcher; attracting young, talented scientists to
Oklahoma; and for developing new research projects,”
said Timothy Lyons, M.D., director of the HHODC.
“These investigators represent the best of what’s to
come, and to have them right here in Oklahoma where
they can have the greatest impact on the health of our
citizens, and in combating diabetes, is significant.”
The 2010 Talley Research Award winners’ funded
projects are these:
Junping Chen, M.D., Ph.D., clinical research
instructor-endocrinology and diabetes – mechanisms
involved in cardiovascular dysfunction in the pre-diabetic phase, with the aim of retarding the progression of
vascular disease.
Zhongchao Han, M.D., Ph.D., assistant professor of research, Department of Cell Biology – treatment of neuroocular- and neuroocular-related disorders via gene therapies.
Transplant Center Opens At OU Medical Center
Junping Chen, M.D., Ph.D., is one of four recipients of 2010 Talley
Research Awards for their work in diabetes. The awards were
established in honor of OU alumnus William “Bill” Talley II, Ph.D.
Chen is clinical research instructor-endocrinology and diabetes at
the Harold Hamm Oklahoma Diabetes Center.
Xichun Yu, M.D., assistant research professor of medicine-endocrinology – metabolic effects of diabetes on autoantibody production against the heart to decrease the risk of
heart failure in diabetic patients.
Xin (Sarah) Zhang, M.D., assistant professor of medicineendocrinology – cellular mechanisms of vascular inflammatory response in the diabetic retina and new molecular targets
for therapies to prevent vision loss in diabetic patients.
OU Medical Center is the new home of the Oklahoma
Transplant Center and the team recognized as having some
of the best liver transplant outcomes in the nation.
The region's newest comprehensive abdominal transplant program combines the existing adult kidney transplant service and the state's only pediatric kidney transplant
program with liver and pancreas transplantation.
"With the Oklahoma Transplant Center, we have built a
facility that is truly focused on the patient. However, what
we have created is far more than just bricks and mortar,"
said Anthony Sebastian, M.D., director and chief of the
center. "It is the team of physicians and providers that collectively have over a century of experience in transplantation that will provide the most cutting-edge, innovative and
highest quality of care for patients requiring transplants in
Oklahoma City, the state and throughout the region."
Sebastian, who is also a transplant surgeon, leads a team
of transplant physicians that include hepatologist Harlan
Wright, M.D., medical director of liver transplantation;
hepatologist Rajesh Kanagala, M.D.; urologist Puneet Sindhwani, M.D., surgical director of kidney transplantation;
Shi-Feng Li, M.D., procurement surgeon; nephrologist Ben
Cowley, M.D., medical director of kidney and pancreas
transplantation; and pediatric nephrologist Martin Turman,
M.D., medical director of pediatric kidney transplantation.
"OU Medical Center, in combination with Children's Hospital, offers our patients access to medical care that is not available
anywhere else in the state," said Sebastian. "With the latest medical equipment, a hospital dedicated to only treating children,
access to the renowned
specialists in OU Physicians
and OU Children's Physicians, cutting-edge medical research and medical
collaboration, this was the
right decision for the transplant community."
The Oklahoma Transplant Center initially focuses on liver, kidney and
pancreas transplantation,
Anthony Sebastian, M.D.
but plans to expand the
program to include other
solid organs for both pediatric and adult patients.
Traditionally, transplant centers are located at major
academic centers where the unique combination of progressive patient care and advanced medical research converge to provide a cutting edge to health care. At OU, the transplant team will have close collaboration with the Harold Hamm Oklahoma Diabetes
Center. This greatly enhances the team's ability to
treat patients and conduct pancreas and liver disease
research. Similarly, the close working relationship
with the comprehensive cancer program at the OU
Cancer Institute greatly expands the treatment options for patients with liver and kidney cancers. All transplant procedures for children are performed in The Children's Hospital.
Rubenstein Named Chair of Geriatric Medicine
Laurence Rubenstein, M.D., MPH, an internationally
known expert on fall prevention, is the new chair of the
Reynolds Department of Geriatric Medicine. His appointment was approved by the OU Board of Regents in
March, and he began his duties July 1.
“We look forward to the new directions for the
Reynolds Department of Geriatric Medicine under the
leadership of Dr. Rubenstein,” said Executive Dean M.
Dewayne Andrews.
Rubenstein previously was professor of medicine at
the University of California David Geffin School of Medi-
cine and director of the VA Greater Los Angeles Healthcare
System’s Geriatric Research, Education and Clinical Center,
Sepulveda and West Los Angeles Divisions. He also was adjunct
professor at the University of Southern California Davis School
of Gerontology, Ethel Percy Andrus Gerontology Center.
He received his medical degree from the Albert Einstein
College of Medicine, New York, in 1974, and took his residency
training in internal medicine at the Albert Einstein-Bronx
Municipal Hospital Center and the UCLA Medical Center. He
received a master’s degree from the UCLA School of Public
Health in 1979. Rubenstein completed a fellowship as a Robert Wood
Johnson Clinical Scholar with training in health services research, public health, and health policy and administration. He is board certified in internal medicine, preventive medicine
and geriatrics.
Rubenstein has authored over 200 peer-reviewed papers, authored/edited 29 books and 100 book chapters, and given many
presentations throughout the world in the field of geriatrics.
He chaired the international committee that developed
clinical practice guidelines for fall prevention.
Rubenstein is a fellow of the American College of Phy-
sicians, Royal Society of
Medicine and Gerontological
Society of America. He has
received the Arthur Cherkin
Faculty Achievement Award
from UCLA, the Society of
Honor Research Award from
the Spanish Geriatrics Society
and the American Geriatrics
Society Award for Achievement in Geriatric Research.
Laurence Rubenstein, M.D.
[ FALL 2010 ]
PG. 3
V I TA L S I G N S
Krempl Named Chair of ORL
Head and neck cancer surgeon Greg A. Krempl,
M.D., has been named chair of the Department of
Otorhinolaryngology, succeeding Jesus Medina, M.D.,
who held the post from 1991 to 2008. Krempl had
been interim chair and “carried out his duties in an
exemplary manner,” said Executive Dean M. Dewayne
Andrews, M.D., in announcing the appointment.
“The department under Dr. Medina's prior leadership established a very solid foundation, and the chance
to be involved in building upon that to further excellent patient care, resident education and seek advances
in the field is a great privilege for me,” Krempl said.
A native of New York, Krempl received his medical degree from the OU College of Medicine in 1992. He completed an internship in general surgery at
the Johns Hopkins Hospital, followed by residency
training in otolaryngology at the University of Texas
Health Science Center in San Antonio. He returned to
Oklahoma City for a fellowship in head and neck on-
Michael Weisz Receives Master Teacher Award
cologic surgery at the OU
Health Sciences Center. Krempl joined the
faculty of the College of
Medicine in 1999 and served
“with distinction in a variety
of important roles in the
Department of Otorhinolaryngology,” Andrews said.
Greg A. Krempl, M.D.
Krempl’s journal publications concentrate on
head and neck cancer and on parathyroid disease. “The administrations of the college and the OU Medical
Center are very pleased that Dr. Krempl has agreed to serve
as the chairman,” Andrews said. “We look forward to his
continuing leadership of the department.”
Krempl describes the head and neck cancer program’s
multidisciplinary patient-centered approach to patient care
on Page 16.
Sivaram Succeeds Sheldon in CME Administration
C.A. Sivaram, M.D., David Ross Boyd Professor of
Medicine, has been appointed associate dean for continuing professional development to succeed Roger
E. Sheldon, M.D., who retired in June as professor of
pediatrics and assistant dean for continuing medical
education.
In this part-time position, Sivaram will oversee
continuing medical activities for the College of Medicine and provide direction for expanding the concept
of continuing professional development for physicians
and others in the health care workforce, said Executive Dean M. Dewayne Andrews, M.D.
Andrews described Sivaram as “a highly regarded
member of the cardiovascular diseases section of the
Department of Medicine and an outstanding educator
who has been recognized repeatedly for his exceptional teaching skills.”
Andrews praised Sheldon for his “exceptional
service” during a period of changes in CME offerings
and requirements, and he added, “We are deeply grateful
to Dr. Sheldon for his commitment to continuing medical
education and oversight of the Office of Continuing Medical
Education.”
clerkship director and the interim program director of
Michael Weisz, M.D., executive vice chair of the Departthe internal medicine residency program.
ment of Internal Medicine at the OU School of Community
Weisz has been an active member of the American
Medicine in Tulsa, was recipient of the 2010 Stanton L. Young
College of Physicians for more than 20 years. He was
Master Teacher Award presented in April.
an original member of the national ACP Council of
The Stanton L. Young Master Teacher Award was established
Associates in 1989 and has served as vice chair of the
in 1983 through an endowment made by Oklahoma City busiACP national membernessman Stanton L. Young.
ship committee. He
The award is given annually
regularly reviews arto a faculty member in the OU
ticles for the Annals of
College of Medicine. This is
Internal Medicine.
the 23rd year for the award
He was elected as
and the honoree receives
governor of the Okla$15,000, one of the largest in
homa Chapter of the
the nation for medical teachACP in 2003, serving
ing excellence.
until 2007.
In 2008,
Weisz was born in Borger,
he was given the ACP
Texas, and reared in Tulsa.
Laureate award.
He attended the University
Weisz has mentored
of Oklahoma and graduated
many residents and
from the OU College of
medical students in their
Pharmacy in 1976. He pracscholarly presentations
ticed pharmacy at Hillcrest
for state and national
Medical Center in Tulsa for
ACP meetings, including
seven years and was director
Stanton L. Young poses with Michael Weisz, M.D., recipient of
two resident presentaof education for the pharthe 2010 Master Teacher Award created by Young to recognize
medical
teaching
excellence
in
the
OU
College
of
Medicine.
tions and one student
macy department. In 1984,
Weisz is executive vice chair of the Department of Internal
presentation
chosen
he entered the OU College
Medicine at the OU School of Community Medicine in Tulsa.
among
the
top
10
in the
of Medicine, where he was a
nation.
member of Alpha Omega Alpha honor society.
He
has
an
active
practice
in
general internal medi He trained in internal medicine at the OU College of
cine and a specialty practice focused on the manageMedicine-Tulsa and in 1992 joined the faculty. In addition to
ment of patients with primary headache disorders.
his current position, he is also the third year medical resident
Edmond Hospital Becomes Part of OU Medical Center
C.A. Sivaram, M.D.
Roger E. Sheldon, M.D.
Edmond Medical Center became OU Medical Center Edmond last spring as that city’s only hospital merged with OU
Medical Center and brought increased services to the region
immediately north of Oklahoma City.
“The joining of these two hospitals brings to the citizens
of Edmond all the benefits of a large, tertiary hospital with
the feel of a community hospital,” said Cole Eslyn, president
and chief executive officer of OU Medical Center.
Eslyn said an immediate investment of $17 million in fac-
ulty and technology enhancements will be followed
by more expansions in the future.
Initially, additional services available include the
reintroduction of labor and delivery services that were
dropped in 2005; a Women’s Center of Excellence,
featuring high-risk obstetrics, gynecologic oncology
care, and breast surgery and diagnostic and therapeutic imaging; enhanced surgical floors; and a renovated
and expanded emergency department.
[ FALL 2010 ]
PG. 5
V I TA L S I G N S
Brightbill Named Assistant Dean
OU Researchers Receive Gates Foundation Awards
Jon S. Brightbill assumed the position of assistant dean for administration for the College of Medicine in
June after serving as project manager
and as special assistant to Executive
Dean M. Dewayne Andrews, M.D.
After joining the college in January
2009, Brightbill “took on many assignments and progressively increasing
responsibilities in a variety of areas,
demonstrating excellent capability
and outstanding performance in all,”
Jon S. Brightbill
Andrews said.
“In this new position, Jon’s duties
and responsibilities will transition into a much broader
range of administrative areas to assist us in these increasingly complex times,” he added.
Experienced in leadership development, education and training for the U.S. Air Force, Brightbill
A novel approach to stimulating the immune system with low-voltage pulses has
won Sunil K. Joshi, assistant professor of
microbiology and immunology, a $100,000
Grand Challenges Explorations grant from
the Bill & Melinda Gates Foundation.
Joshi’s project, “Development of Safe,
Cost-effective and Functional Strategy for
Immune Intervention,” will study whether
using an Electric Wave-Pulse near lymphoid tissues can stimulate the activation
of dendritic cells and promote an immune
response.
Sunil Joshi, Ph.D.
If successful, the technology could raise the
effectiveness of vaccines in populations where the majority
have impaired or weak immunity against infectious diseases
due to malnutrition, overcrowding, poor socio-economic and
poor hygenic conditions. These populations are at increased
was dean of education for the U.S. Air
Force Airman Leadership School between
1999 and 2006 at Altus and Sheppard Air
Force bases, and before that was instructor
supervisor at Sheppard AFB for emergency
medical technician training and medical
readiness courses. Prior to joining the College of Medicine, he was lead supervisor of
the medical section of the Oklahoma City
Military Entrance Processing Station.
Brightbill was twice the recipient of the
prestigious John L. Levitow Award as the
honor graduate of both the U.S. Air Force’s
senior non-commissioned officer academy
and non-commissioned officer academy. He also received
the Defense Meritorious Service Medal, the Air Force Meritorious Service Medal on three occasions and the Air Force
Commendation Medal four times.
He graduated from Wayland Baptist University with a
degree in occupational education.
risk for infections and can experience
more severe and complicated courses
of disease.
Also receiving one of 78 Grand
Challenges Explorations grants
were Robert H. Broyles, Ph.D., adjunct professor of biochemistry and
molecular biology, and the Sickle
Cell Cure Foundation he heads, for
an innovative approach to malaria
resistance.
Broyles’ research builds on his
discovery of a way to shut off the
sickle cell gene and reactivate a fetal hemoglobin gene in its place. This manipulation
not only affects sickle cell disease but also confers
malaria resistance. Broyles founded the Sickle Cell
Cure Foundation in 2006.
Emergencies Real, Patients Are Not
Physician assistants listen intently as Jason Lees, M.D., assistant professor of surgery, uses a high-tech human simulator to provide emergency
medicine training in the Clinical Skills Education and Testing Center. From left are Lees and PAs Prince Taylor, Yukon, in the black cap; Brad Smith,
Oklahoma City; and Ronnie Taylor, Oklahoma City. Smith was an instructor during the two-day workshop, the first of its kind in the nation.
Physician assistants from Oklahoma and 19 other states
were given a unique training opportunity last spring in
which the emergencies were real, but the patients were not.
The two-day workshop in the Clinical Skills Education
and Testing Center was the first competency-based emergency medicine training session of its kind in the United
States. It was sponsored by the Oklahoma Academy of Physician Assistants.
The training gave PAs the opportunity to practice
advanced procedures and emergency medicine on hightech human simulators programmed to respond as a real
patient would in hundreds of different simulated medical
scenarios. The simulators allowed participants to focus on
emergency skills, like placing chest tubes, obtaining an
airway and using ultrasound to identify intra-abdominal
bleeding, and to learn to function effectively as a team in a
variety of emergency situations.
“Our high-fidelity simulators are very much like
real patients with eye reflexes, a pulse, blood pressure
and more,” said Rhonda Sparks, M.D., medical director of the CSETC. “We can manipulate the technology to create situations the learner has to deal with in
real time. So it requires you to learn to think, adapt
and react.”
“It is important to provide opportunities like this
skills workshop to prepare physician assistants for the
potential life-saving situations they encounter,” said
Dan McNeill, Ph.D., PA-C, physician assistant program
director for the OU College of Medicine.
“This workshop gave medical professionals the
hands-on practice necessary to develop highly advanced skills in a safe, controlled and realistic medical
environment. In conjunction with the CSETC, we’ve
very excited to offer this kind of competency-based
training for the very first time.”
[ FALL 2010 ]
PG. 7
V I TA L S I G N S
Physicians Taught How to Detect Autism in Toddlers
Gene Therapy Halts Blindness
Toddlers with autism spectrum disorders can be
helped significantly by intensive intervention, OU
Medicine researchers are showing, but first, ASD has to
be identified early by these children’s physicians.
The skills needed to make this evaluation and diagnosis are being taught to Oklahoma pediatricians
through an OU-led component of the Autism Workforce Initiative called START-ED, for Screening Tools
and Referral Training – Evaluation and Diagnosis.
“Pediatricians across the state are grappling with
what to do as more and more families request help in answering the question, ‘Does my child have autism?’ We
know that waiting for a diagnosis can significantly delay
the start of early intervention services, which can be crucial for optimizing outcomes for these children and their
families,” said Laura McGuinn, M.D., assistant professor
of pediatrics and director of the START-ED project.
The free, day-and-a-half-long training program was
developed at Vanderbilt University and provides intensive physician training on how to perform a new, hourlong diagnostic visit, as well as support for implementation in the physicians’ office following the training.
Bonnie McBride, Ph.D., assistant professor of pediatrics,
is principal investigator of the Early Foundations Project,
another component of the Autism Workforce Initiative.
She said the model project for toddlers, funded by
the Oklahoma State Department of Education using
federal dollars, provides play groups, home and community support, monthly parent education, intervention on family-chosen goals and intensive, individual-
carrier had been developed, she immediately wanted
An OU Medicine vision researcher has discovered a way
to test its use in the eye. She now hopes to collaborate
to use a radical new type of gene therapy to prevent blindsoon with Robert E. Leonard, M.D., clinical associate
ness caused by retinitis pigmentosa, giving hope to the estiprofessor of ophthalmology at the Dean McGee Eye
mated 100,000 Americans who suffer from the disease.
Institute, to take the
Muna Naash, Ph.D.,
therapy to eye paprofessor of cell bioltients.
ogy, collaborated with
"It's breathtaking,”
scientists in Cleveland
Leonard said of Naand Buffalo in usash’s research.
ing a non-viral, DNA
“This is an incrednanoparticle carrier to
ible breakthrough in
reach the light-sensitive
terms of being able
retinal cells affected by
to treat with gene
this genetic disease.
therapy. Outside of
The procedure cargene therapy, we are
ries the therapy to the
at a loss to be able to
right spot in the eye
treat these patients,
within 15 minutes in
so this is incredibly
animal models.
important research.
The technique alIt’s breathtaking, very
ready is being used to
exciting.”
develop new treatments
Ophthalmologist
Robert
E.
Leonard,
M.D.,
and
vision
researcher
Muna
The research on
for another eye disease
Naash, Ph.D., chat with retinitis pigmentosa patient Tracie Harris folretinitis pigmentosa
– macular degeneralowing a news conference about Naash’s research to halt the disease.
at the OU Health Scition, the leading cause of
ences Center is supblindness in the United
ported by a grant from the National Eye Institute and
States. The technique could eventually be used in treatments
the Foundation Fighting Blindness.
of other diseases resulting from genetic defects, Naash said. It
The study appears in the Journal of the Federaalready is being tested for treatment of cystic fibrosis.
tion of American Societies for Experimental Biology.
Naash said that when she first learned that a nanoparticle
ized teaching techniques.
“We know that half of
children identified with a
possible ASD respond significantly to early intervention.
This program expands and
intensifies that intervention
from two to four hours
per month to 17 hours per
week,” McBride said.
“It’s awesome.
It’s
changed our lives,” said
Bonnie McBride, Ph.D.
Steve Davis of Oklahoma
City, whose son, Blaine,
began to use sign language,
point and allow his parents
to touch him through his
participation the program.
The program is offered
as component of the early
intervention services provide through SoonerStart
and is free to families. The
program has expanded
from the Oklahoma City
model site into Canadian
Laura McGuinn, M.D.
and Cleveland counties.
The national prevalence rate of autism is one in every 110 children.
Aping Human Treatment
Helps Gorilla
LaTasha Craig, M.D.
By applying expertise used with her human patients,
OU obstetrician-gynecologist LaTasha Craig was able to
identify and solve the infertility problems that were keeping Kelele, 16, a rare Western lowland gorilla at the Oklahoma City Zoo, from becoming pregnant.
Craig, an infertility specialist, discovered the level of
the hormone prolactin in Kelele’s body was more than 12
times the normal amount and keeping Kelele from ovulating. The source appeared to be a microscopic bump that
the OU physicians found on Kelele’s pituitary gland.
The gorilla was put on a human dose of cabergoline
twice a week and later started on human fertility drugs.
Craig said Kelele’s condition is fairly common and an oftentreatable cause of infertility in humans.
Kelele’s treatment began in late winter, and zoo
officials said she and mate Bom Bom could expect
to be expecting in the fall. Zoo vets use the same
human pregnancy tests that people buy at the drug
store. They collect Kelele’s urine and watch the stick
for a positive result.
[ FALL 2010 ]
PG. 9
OU CANCER INSTITUTE
Robert S. Mannel, M.D., director of the OU
Cancer Institute and chair of the Department of Obstetrics and Gynecology, pictured
in front of the seven-floor institute building.
New Era
OU Cancer Institute Opens
in Cancer Care
A n e w e r a i n c a n c e r c a re b e g i n s n e x t y e a r w h e n O k l a h o m a ’s o n l y
c o m p re h e n s i v e a c a d e m i c c a n c e r c e n t e r o p e n s t h e d o o r s t o a
$120 million building designed specifically to meet the medical,
emotional and practical needs of patients and their families.
No ordinary clinic, the institute’s combination of care,
research and focus on the patient will make it “a center truly
for healing, and healing the whole person, not just the disease,” said OU President David L. Boren.
“The OU Cancer Institute puts the patients at the center” in the fight against their cancer and gives them access
to the latest therapies available, said Robert S. Mannel, M.D.,
the center’s director, holder of the Rainbolt Family Chair
in Cancer and chair of the Department of Obstetrics and
Gynecology.
Putting patients at the center of their care means that
the patient has a multidisciplinary medical team of cancer
specialists who go together to the patient to discuss his or
her comprehensive treatment plan in a one-appointment,
one-location experience.
In addition, a multidisciplinary team of complementary
support personnel, from a financial counselor to a registered
dietitian, will work with the patient in a coordinated man-
ner to create an individualized survivorship plan.
“These teams go hand in hand, so it’s not just focused on
the specific cancer but the broader construct of where the
patient is coming from – the impact on the individual, the
family, the job and his or her emotional and physical wellbeing,” Mannel said.
The 210,000-square-foot OUCI building – a new landmark
on the OU Health Sciences Center campus – was designed to
integrate all patient services and put them within easy reach
of patients and their families.
It will provide:
• Comprehensive outpatient medical services
• Dedicated space for treatment of women’s cancers
• Comfortable private, semi-private and communal chemotherapy infusion rooms
• The most modern radiation therapy facilities, including the
latest generation of proton radiation therapy
• Phase I clinical trials center to give late-stage cancer
New Era continued on page 12
[ FALL 2010 ]
PG. 11
OU CANCER INSTITUTE
Described as the “living room” of the OU Cancer Institute, the first floor lobby is designed to provide a comfortable and relaxing environment
for patients and their families. A meditation room, family lounge, patient education center, full-service cafeteria and Diagnostic Imaging Center
also are on the first floor.
The Healing Garden, accessed from the lower level of the OU Cancer Institute building, features beautiful plants, flowers, trees
and waterfalls.
New Era continued from page 11
patients access to the newest treatment options
• A Healing Garden
• Meditation Room
• Food service with nutritious hot and cold meals
The building’s design also accommodates special
services, which include a salon with wigs and turbans
for patients going through chemotherapy, breast prostheses and other appearance-related items that meet
the special needs of cancer patients.
A massage therapy program is planned to help ease
the localized swelling from lymphedema. Art and pet
therapy will be offered, as will tobacco cessation support.
Patient Services will assist patients and families in
accessing the medical, financial and educational services they require. Nurse navigators provide the essential
coordination of multidisciplinary care.
Especially important in carrying out the theme
of patient-centered care are the building’s aesthetics,
and a special effort led by OU First Lady Molly Boren is
ensuring an atmosphere in which every space is warm
and welcoming for patients and their families.
From the interior décor of examination rooms to
the Healing Garden with its fountains, and from full
food service to the mural of a sunrise in a peaceful
meditation room, patients will be enveloped in an environment created for their comfort.
“It’s exciting, it’s beautiful . . . it’s all designed
around patient-centered care," Mannel said. “We ask ourselves, ‘Is what I’m doing making the journey of this patient
and this family a better experience? Am I making their journey as non-traumatic as possible?’”
Another important dimension of the patient’s treatment
journey is his or her access to cutting-edge drug trials at
Oklahoma’s only Phase I Clinical Trials Center, as well as to
participation in an expanding program of Phase II and III trials
of new therapies and combinations of therapies already in use.
“Our goal isn’t to create just another place where a cancer
patient can go to get care,” Mannel said. “We want a center of
excellence that’s nationally known. That’s our bar, and being
a Phase 1 center is an important part of that because it means
we will have drugs available at the University of Oklahoma
that only a few select sites in the country are using.
“It’s important to the state of Oklahoma that we’re able
to do that.”
Mannel said the three-year goal of the Phase 1 program is
to have 30 trials open at any one time to patients with latestage cancers “who have run out of FDA-approved therapies
but who still want to fight the cancer and want to forward
the knowledge of how to fight cancer.”
No comprehensive cancer center can be complete without the scientists who search for better understanding of
the complex origins of cancer, find targets for new drugs,
develop new therapies and explain why new drugs do – or
don’t – work as intended.
Mannel said the OUCI has a five-year growth plan that will
add 20 cancer researchers and 31 cancer physicians to the team. A
$50 million private fundraising campaign led by Jim and Christy
Everest has been very successful in creating privately funded faculty endowments that can be offered to prospective recruits.
neuro-oncology patient navigator and American Indian
patient navigator is provided, respectively, by the Steve
Moore Endowed Chair in Head and Neck Cancers, the
Inasmuch Foundation and the Chickasaw Nation.
Three master’s degree-level social workers are avail-
The mission of OU Cancer Institute is to improve and extend
the lives of cancer patients through:
Providing patient-centered, comprehensive care,
Conducting innovative basic, translational and clinical research,
Raising the level of cancer awareness and prevention
among individuals and populations,
Educating the next generation of cancer health care professionals, and
Serving as a statewide resource for patients, researchers,
health professionals and communities.
Support for specific patient support programs has come
from a number of generous sources, among them members of
professional horse associations nationwide who have contributed more than $300,000 to date in support of the Shirley Bowman Nutrition Clinic. This nutrition program will not only
provide nutritional support for patients but also train cancer
nutritionists for work in other settings around the state.
Support for the head and neck cancer patient navigator,
able to clinic out-patients, with that number to grow
to five by 2013. Support for these positions comes from
the Inasmuch Foundation, the E.L. and Thelma Gaylord
Foundation and Blue Cross Blue Shield of Oklahoma.
Blue Cross Blue Shield also helps fund the assistance
provided to patients through financial counseling.
“Education, of course, is always going to be a big part of
New Era continued on page 14
[ FALL 2010 ]
PG. 13
OU CANCER INSTITUTE
New Era continued from page 13
what we do,” Mannel said. “The traditional professions
we think about are physicians and nurses, but we are also
creating educational programs for other disciplines,”
such as the nutritionist training with the College of Allied Health and a master’s degree program in cancer social
work in collaboration with the Anne and Henry Zarrow
School of Social Work on the OU campus in Norman.
Ensuring that patients and their caregivers have
the information they need to aid in treatment and
recovery is an integral component of the OU Cancer
Institute. All clinics will have computer monitors with access to educational material, and a large patient resources
center will provide Wi-Fi access to the Internet, Mannel said.
“The overarching mission of OUCI is to raise the level
of cancer care for the citizens of Oklahoma and reduce the
incidence and burden of cancer on our society. We hope
that by creating such an institution and educating the
professionals who fight cancer – from the physician to the
nutritionist – these professionals will go to other parts of
the state and create similar patient care environments.”
Examination rooms in the OU Cancer Institute are designed to inspire and
encourage patients. Each clinic area offers dedicated space for consultations
with members of the Patient and Family Services staff, who include nutritionists,
social workers and financial counselors.
Bright, open and airy describes the OU Cancer
Institute’s atrium, with its tall windows and
multi-story view.
“It’s so important for cancer patients to be able to stay
at home with their loved ones, with those who care
about them, with those who support them instead of traveling
500 miles away for their cancer treatment.
That’s what will be so very special about this institute.”
- OU President David L. Boren
A quiet meditation room for reflection and prayer will be available to patients and their families.
Room-Naming Opportunities
Naming a room for a family or to celebrate the wellness or memory of a loved one is a tangible way that
Oklahomans are making the OU Cancer Institute a
reality. Permanent naming opportunities in the building are available for charitable gifts of at least $10,000.
These gifts are payable over three years.
If you are interested in making a charitable gift to the
OU Cancer Institute, please contact Von Allen, director of
development, at (405) 271-4880 or [email protected].
Examples of locations and gift amounts are these:
Exam rooms and faculty offices – $10,000 each
Reception desks/waiting areas – $20,000 each
Section chief and department chair offices – $25,000 each
Conference rooms – $50,000 each
OUCI Director's office – $50,000
Executive Conference Room – $100,000
Mutlidisciplinary Cancer Clinics – $1 million each
[ FALL 2010 ]
PG. 15
PAT I E N T C A R E
Greg A. Krempl, M.D., chair of the Department of Otorhinolaryngology. Seated at right are patient navigator Gwenda Lantz, who
does a needs assessment and initiates the ancillary services that patients need, and Robert Rodriguez, patient services representative.
Q & A: What Is Patient-Centered
Multidisciplinary Care?
Patients at the OU Cancer Institute will experience
care that centers on their needs and their schedules.
Patient-centered multidisciplinary care has long been
the practice of the head and neck cancer division of the
Department of Otorhinolaryngology. It was introduced
by the department’s longtime former chair, Jesus E. Medina, M.D., and refined into the practice model used
today. In an interview with OU Medicine, department
chair and cancer surgeon Greg A. Krempl, M.D., describes how putting the patient first improves their care.
Krempl holds the Steve E. Moore Endowed Chair in
Head and Neck Cancer.
How does patient-centered multidisciplinary care
differ from standard practice?
Provider-centered care is at the convenience of the provider,
whether or not it’s convenient for the patient. Most often, seeing multiple doctors means multiple separate appointments.
With patient-centered multidisciplinary care, you mobilize the people you need to build an appointment in a way
that’s patient-centered, with the surgeon, medical oncologist and radiation oncologist seeing the patient together,
with support staff, to provide comprehensive care. It’s a
complete model reversal because you’re thinking of patients
and their needs.
So when a referral is made for Jane Doe to come to
your clinic...
Previously, our clinic would receive a referral for Jane
Doe that would traditionally go to a scheduler. The scheduler would book an appointment and the scheduler might
ask the referring provider to send us the records so we have
them when the patient arrives.
In the model we have put together, a trained nurse navigator gets Jane Doe’s records and reviews them to see if they
are complete. The nurse navigator then obtains any missing
records before Jane’s arrival.
Before we had this in place, 60 percent of the new patient’s
outside record packets were incomplete when the patient arrived
for the first visit. We would have to schedule a second appointment so that CT scans, X-rays, etc., could be reviewed and a treatment plan made. With the new model, when the patient arrives,
we have much more complete outside records, allowing us to
formulate treatment at the initial visit in many cases.
By merging visits one and two into the initial visit, we
were able to open the second visit slot to another new patient, and this instantly increased our availability. The time
from phone call to first visit went from 10 to 14 days to three
to seven days for new cancer patients.
What else does the nurse navigator do?
The nurse navigator also makes a determination what
type of appointment the patient needs, because not all patients need the multidisplinary team, just a surgeon. This
is why the triage component is important. The nurse
navigator identifies these patients and schedules according
to their multidisciplinary needs so that the team’s time is
better utilized. In addition, the nurse navigator ensures that
each new cancer case is presented at a weekly meeting of
our multidisciplinary tumor board. She follows up with the
patient to schedule necessary treatment and procedures and
collaborates with the clinical trials office.
Does the patient see everyone at one time?
Yes, the three-member team examines the patient together. Usually, the team will leave the exam room to look
at X-rays, discuss options, and, in most instances, all members return together to give a consensus opinion of where
we’re headed with the treatment and the next steps.
Each support services member of the team – a nutritionist, for example – knows when these multidisciplinary clinics
and tumor boards are held and is available to see the patient as
needed. Support services are staggered so that the patient is not
overwhelmed with five or six different providers at one time.
How do you know if a patient needs the nutritionist,
for example?
A needs assessment to determine what services the patient
may need is conducted by a patient navigator, who visits with
the patient to assess a variety of issues and initiates the ancillary
services we need to mobilize. Because many of our patients lose
weight and have difficulty swallowing, the assessment will pick
up the need for a patient to meet with the nutritionist.
The appointment sounds like a busy time for the
patients and their doctors.
We utilize the time of the physician team to its fullest by
scheduling according to the patients who need all three of us.
How have patients responded to the multidisciplinary care model?
We think our patients like and prefer the multidisciplinary model because their treatment can start so much
sooner by eliminating so many different appointments.
Is a reconstructive surgeon part of the multidisciplinary clinic?
The microvascular and reconstructive surgeon in our
department is not part of the multidisplinary team because
so many of his patients require special tests. We have found
that it is best for the patients to have these tests on their
initial visit with us, then see him on a separate visit when all
of the test results are available.
What has resulted from the shift to patient-centered
multidisciplinary care?
Our focus is to provide the absolute best care in the fastest manner you can and offer it to the broadest spectrum of
people, and we think the patient-centered multidisplinary
care model goes a long way in making that possible.
With one-half of our patients traveling at least 50 miles
or further for care, this model can mean less time patients
are away from home, less travel and expense, and the piece
of mind that their care is being managed comprehensively.
Do your patients ever ask the team about their survival chances?
Patients don’t ask it very often. Their most urgent need to
know is whether there’s a chance for curing them, and where
they are headed – surgery, radiation or chemotherapy or all of
the above, and in what order.
The thing I tell our patients is that we don’t quote statistics
to patients because we all believe there always is also a hope
factor. If we tell someone that their chances of cure are 5 percent, their hope factor is going to go down pretty low, along
with their willingness to complete a tough course of therapy.
A positive attitude going into difficult therapy gives the patient a better outlook and strength to get through it.
We say that if there is a reasonable chance for cure, let’s
all get on board and go for it 100 percent.
[ FALL 2010 ]
PG. 17
PAT I E N T C A R E
Orthopedic oncologist Jeremy R. White, M.D. The X-ray in the background shows the replacement knee and metal prosthesis
used in a young patient with cancer in the tibia.
Life and Limb
For the child whose unbearable leg pain is diagnosed
with osteosarcoma to the elderly metastatic bone disease patient with a broken hip, the OU Cancer Institute
offers a new dimension in care through the expertise of
orthopedic oncologist Jeremy R. White, M.D.
White, a self-described limb salvage specialist, uses
state-of-the-art alternatives to amputation whenever
possible to keep his patients both alive and whole.
The country’s 250 orthopedic oncologists treat both
bone and soft tissue tumors, benign and malignant. White’s
particular focus is on sarcomas, which are potentially
deadly and especially dangerous when the patient’s care
has been compromised early in its treatment.
“There are a lot of pitfalls in their management,” White
said. The outcome can be influenced significantly if the area
is contaminated by a biopsy that is in the wrong place, the
incorrect orientation of an incision, or a drain hole placed
far from the surgical site.
“With sarcomas, the tumor has to be removed with a
wide margin, and because sarcomas will seed and grow,
we have to cut out everything that’s been touched” in
a previous procedure, White said. Although 60 to 70 percent of bone sarcomas occur in
children and adolescents, making them a major childhood
cancer, they are rare in comparison to carcinomas. Bone
tumors are the third leading cause of mortality in children
aged 10 to 14 in the United States.
Amputation was once the standard of care in these
cases, but no more. “Now, 95 percent of the time we
don’t amputate. Treatment for most bone sarcomas is
neo-adjuvant chemotherapy, then surgery and reconstruction, and chemotherapy afterwards,” White said.
Limb salvage in people with sarcomas offers the same
survival rate as amputation, he added, crediting advances
in chemotherapy for saving the lives of people with metastatic disease and limb salvage for improving quality of
their lives.
White said that 80 to 85 percent of the time, a highgrade bone sarcoma has metastasized to the lungs by the
time it is diagnosed, so it is always treated as if it has spread.
Occasionally, an adult won’t elect to have treatment, but
“almost everybody does, especially children, who always
receive aggressive treatment.”
This involves chemotherapy before and after surgery
and wide excision of the tumor followed by reconstruction
of the resulting bony defect with metal prostheses, bone
graft, or a combination of the two. The challenge for the
surgeon is to remove the entire tumor while preserving
tendons, nerves and vessels.
Dealing with malignancies, whether in the bone or in
the soft tissues of the extremities and pelvis, can be more
stressful than a typical orthopedics practice, “but it is
rewarding. People come in with a completely unknown
problem … a soft tissue mass, a bone mass or bone pain.
The surgeries are always different, and always I have to have
a bag of tricks, which includes metal prosthetics, allograft
bone, cadaver bone and the composite things we do.”
A special item in that bag of tricks is a so-called “growing
prosthesis” for use in pediatric cancer patients. A version
of this prosthesis can be lengthened in the office with an
electromagnetic field. This allows the expandable prosthesis to grow as the child grows without additional surgeries.
The expandable component is most often fitted with a
replacement knee or hip, depending on the site of the
cancer.
Despite White’s interest and focus on sarcomas,
some of his practice involves the much more common
metastatic bone disease. Success in limiting morbidity
has been improved by the use of intravenous bisphosponates, an osteoporosis medicine that helps to prevent fractures in cancer-weakened bones.
“It’s important to fix things before they break, when
possible,” White said. In some cases, a risk assessment
may indicate the insertion of a rod, a hip replacement
or removal of a tumor and filling the gap with bone cement in combination of a plate or rod.
Frequently, such cases will involve an older person
with metastatic carcinoma, a poor prognosis and a
large and painful lesion – or even a break – in his hip.
“A cure may not be achievable, but this hip is going
to hurt without surgery and he won’t be able to get
around. If the hip is broken, he’s bedridden, and if you
fix it, he can get out of bed and walk the next day. This
gives us a chance to dramatically improve his quality
of life.
“Every few weeks I see someone with carcinoma
and a break that will take a pretty big surgery to fix.
There is always the question of whether the risk of intervention is worth the benefit, and am I going to help
by doing the surgery. Most often, the answer is, ‘Yes.’”
White said a multidisciplinary team approach is the
best way to offer coordinated services for his complicated cases, and he is assembling one at the OU Cancer
Institute that includes radiation oncologists, medical
oncologists (pediatric and adult), musculoskeletal
radiologists and pathologists. All components of this
team are crucial to identifying and appropriately
treating sarcomas.
This will be the only multidisciplinary musculoskeletal tumor and sarcoma program in Oklahoma
dedicated to providing premier care, advancing the
field through research and improving outcomes for
patients with musculoskeletal tumors.
In addition, White is taking his expertise to the OU
School of Community Medicine in Tulsa once a month
to follow up with current tumor patients from that
area and to perform initial evaluations of pediatric and
adult cases.
[ FALL 2010 ]
PG. 19
PAT I E N T C A R E
Three generations of bone marrow and peripheral blood stem cell transplantation specialists are pictured in the transplant unit at OU Medical Center. From
left to right are George B. Selby, M.D., professor of medicine and director of the OU Blood and Marrow Transplant Program; Jennifer Holter, M.D.; and
Robert Epstein, M.D., emeritus professor of oncology-hematology, who performed the first bone marrow transplant at OU in 1982.
Marrow and More
Once considered a desperate Hail Mary pass at the
end of a losing battle against an incurable disease, bone
marrow transplantation has become an integral part
of the treatment plan for many children and adults
with leukemia and other blood disorders.
Newer agents and drug combinations, new capability
to detect the need for earlier transplants, new sources of
blood stem cells, better donor matching and improved
supportive care have contributed to improved outcomes
for people diagnosed with blood cancers, said George B.
Selby, M.D., professor of medicine, director of the OU
Blood and Marrow Transplant Program and holder of the
Gary McKinney Chair of Bone Marrow Diseases.
Since the first successful use of bone marrow stem cells
in 1968 in Seattle by a pioneering team that included Robert Epstein, M.D., OU emeritus professor of oncology-hematology, this relatively recent procedure saves thousands
of lives every year.
Epstein joined the OU faculty in 1981, “and we did the
first transplant here in 1982,” said Selby, who has been involved with the bone marrow transplant program since it
began. Since then, the OU program has performed more
than 2,000 transplants for both adults and children.
As the state’s only comprehensive bone marrow and
peripheral blood stem cell transplant program, it offers OU
Cancer Institute patients a complete palette of options:
• Autologous transplantation of the patient’s own cells
• Allogeneic transplants of cells from siblings
• Allogeneic transplants of cells from unrelated donors
• Umbilical cord blood transplants
• Transplantation in children, a program Selby established
in 1993, is directed by Laura Rooms, M.D.
Healthy stem cells from bone marrow, peripheral blood
or umbilical cord blood give patients a new immune system
by replacing the damaged or destroyed marrow in adults
who have acute myelogenous leukemia (AML), acute lymphocytic leukemia (ALL), chronic lymphocytic leukemia
(CLL), chronic myelogenous leukemia (CML), Hodgkin’s
Disease or lymphomas and in children who have ALL,
AML, Hodgkin’s Disease, lymphomas or other diseases,
such as aplastic anemia and neuroblastoma.
“When we first started, the only stem cell source we
used was bone marrow,” Selby said. “The donor had general
anesthesia, and we removed marrow from the pelvis.”
It then became possible to collect the same blood-forming
stem cells from a blood donor without using anesthesia and
without poking a hole in the pelvis. Although use of peripheral
blood stem cells is a widespread transplantation practice, the
OU program tends to prefer bone marrow because of a difference in the rate of graft-versus-host disease, Selby said.
The next big development in blood stem cell transplantation was the use of umbilical cord blood as the source. Cord
blood is used more for children than for adults since its small
volume, about the amount of a soft drink can, contains a limited quantity of stem cells.
Two cord blood units may be required for an adult recipient, with the result that blood stem cells from three
people intermingle: those remaining from the patient and
those from two different donors. “Eventually, one of the
two cords becomes dominant. When you look at the blood
months later, all of the blood will be that of one donor.”
How this happens is a mystery, Selby said.
Whether the transplantation process uses donor cells
from bone marrow, peripheral blood or umbilical cord
blood, the transfer of an immune system into a different
person requires the use of immunosuppressive drugs until
the transplanted immune cells decide to tolerate their new
body rather than attack it.
This attack process, graft-versus-host disease, continues to be
the bane of transplantation despite newer immunosuppressive
drugs and more sophisticated, DNA-based testing of potential
donor cells that have improved the odds of success significantly.
The first 100 days after a transplant are both critical and
unpleasant for the patient. “It’s a very dangerous time,”
said Selby. Immunosuppression begins immediately,
as do transfusions, because chemotherapy and radiation have caused the patient’s white and red cells and
platelets to plummet. The patient is shielded in isolation to protect from infections until the patient’s new
bone marrow begins to grow.
Antibiotics are given, and those patients who develop
mouth sores are fed intravenously. Most feel weak and
tired. Patients are allowed to return home when their
white count reaches normal levels and they are again
capable of self-care and can remain hydrated without
intravenous fluids.
Having marrow and blood stem cell transplants available through the OU Cancer Institute “is a huge advantage
for Oklahomans because most transplant centers make
the patient stay in the town where the transplant is done
for 90 to 100 days,” should a problem arise, Selby said.
“So if they had to go to Houston or Seattle or Minnesota, not only does the patient have to go, but so does
the caregiver. Many patients are relatively young and
have kids at home. Who’s going to take care of the kids?
Who’s going to be working to keep the wolf from the
door? And where’s the support system?
“But if they are Oklahomans and they come here, they can
stay at home if they’re within a two-hour drive or 100 miles.”
Especially gratifying for Selby is the increased ability to know when a patient needs a transplant, which
is ordinarily done when the patient is in remission.
With AML, for example, a patient’s bone marrow will be
checked for chromosomal mutations in OU Medicine’s
molecular biology labs. Once the lab findings are received, “we can say that this patient will have a good
prognosis with conventional chemotherapy, or we may
see evidence that this patient will relapse immediately,
so we get them a transplant as soon as possible.”
Nonetheless, the national survival rate for AML is just
23.4 percent when all ages are considered but 60.2 percent for children under 15. The news is much better for
ALL, with a survival rate of 90.0 percent for children but
less than 50 percent for adults. The best results are with
chronic myelogenous leukemia (CML) at 78.8 percent.
While CML is rare in children, they sometimes do
develop it and may require a transplant, Selby said.
The first pediatric unrelated donor transplant at
OUMC was performed for CML. “There is nothing
better than treating a little boy for late-stage CML and
then getting to be the commencement speaker at his
high school graduation,” Selby said.
[ FALL 2010 ]
PG. 21
PAT I E N T C A R E
Gynecologic oncologist Scott McMeekin, M.D., OUCI deputy director for clinical research.
Trials Offer Fighting Chance
Every Oklahoma cancer patient will have the opportunity to fight his or her cancer with the latest
experimental therapies available – and without having
to leave the state to do it.
This is the goal of the OU Cancer Institute’s determined clinical trials research team, which is on its way
to reaching its objective by:
• Becoming only the fourth Phase I clinical trials center in
this region of the country.
• Leading the nation in enrollees in later-phase trials of
therapies for women’s cancers that have the potential of
changing the standard of care.
• Establishing a statewide clinical trials network that will
put the latest cancer drugs in the hands of participating
community oncologists around the state.
This massive effort is spearheaded by gynecologic oncologist Scott McMeekin, M.D., OUCI’s deputy director for
clinical research.
His passionate message to Oklahoma cancer patients
and their families is simple: “There is something out there
that’s better, and together we’re going to find it. We’re going to help you with the best treatment, the best way to
impact your cancer, and clinical trials are that way.”
The need for such a program is critical. Oklahoma
ranks 15th in the percentage of its citizens who are diagnosed with cancer. One-half of the men in Oklahoma and
one-in-three women will be diagnosed with cancer at some
point in their lives.
For the lucky ones, the current standard treatment will
be enough to keep them alive and cancer-free for many
years. The rest – those with late-stage, metastatic cancers
and others whose cancer has returned with a vengeance
– have likely heard those dreadful words, “I’m sorry, but
there’s nothing more we can do.”
“But now,” McMeekin said, “there are opportunities for
Oklahoma patients that have never been available before.”
He is referring to the establishment of OU Cancer Institute as a Phase I trial center that can make brand-new,
first-in-human drugs available to patients with metastatic
cancer who have run out of other options and want to keep
fighting their disease.
OUCI is the only Phase I Trial Center within 400 miles.
OU’s venture into this arena was made possible through
a partnership with Sarah Cannon, one of the leading centers in the country, which allows OUCI to participate in
industry trials of its latest and most-promising drugs. McMeekin said OUCI expects to enroll 100 patients in as many
as 25 to 30 Phase I trials within the first year and eventually
include trial drugs available through the National Cancer
Institute.
Most of these state-of-the-art drugs target a mutant
component of the complex network of intracellular and
extracellular signal pathways that regulate cell behavior.
Cancer cells grow when they shouldn’t, they don’t undergo apoptosis and die when they should, and they develop
the capability to grow new blood vessels and invade surrounding tissue.
“It’s a completely different approach of drug development and treatment from 20 years ago,” McMeekin said.
“Then, it was ‘Here’s a drug that kills all cells, let’s see if it
works. Now, it’s ‘Who’s likely to benefit?’”
“It’s a new era, an exciting time,” agreed medical oncologist and drug development specialist Carla
Kurkjian, M.D. “We’re transitioning away from giving all patients the drugs arbitrarily, trying to find the
maximum tolerated dose and moving on to Phase II,”
and instead are focusing on the cellular mechanisms
involved.
One of the Phase 1 drugs she tested during the summer targeted a particular protein, “one very small piece
of the puzzle, a sub-element of a pathway,” that may
provide some immediate benefit to certain patients but
is more likely part of a future, multi-pronged approach.
Medical oncologist Shubham Pant, M.D., said he
tries to match an available Phase I drug with a pathway
identified as being associated with a particular patient’s
cancer “and see how it works.
“We tell the patient there is no proven benefit with
this new drug, and if there is benefit, it is rare, with responses in the ballpark of 5 to 10 percent. On the flip
side, there is no other therapy available. You may help
yourself, but you definitely will help society, the next
person” through participation in a Phase I trial.
“We do see response and sometimes really good response,” Pant said, “so it’s not all doom and gloom.”
Pant cited the case of a patient whose ovarian cancer
failed to respond to the standard, FDA-approved drug,
gemcitabine. But when gemcitabine was given in combination with a new Phase I drug, the woman’s tumors
began to shrink.
Why it worked is a question for scientists. “It’s the
bench-to-bedside approach and back again to the lab,” said
Pant. “We collect tumor and blood and tumor samples
and try to see if (the drug) is suppressing the target or not.
“It’s all a process of learning how the drug is broken
down, how it affects pathways. What we are trying to do
is personalize medicine. Everybody’s tumors are different.
Years into the future we will be able to say, ‘This drug is for
you . . . this drug will hit your pathway.’ You will be able
to personalize (therapies) for every different patient.
“Science is a long and sometimes very painful road,
and (Phase I) participants realize we’re all working toward a common goal.”
“Patients are much more altruistic than we might
give them credit for,” Kurkjian said. “They want to
advance science, but it’s a delicate conversation. There
Fighting Chance continued on page 24
[ FALL 2010 ]
PG. 23
PAT I E N T C A R E
Fighting Chance continued from page 23
may be no benefit for that patient.”
On the other hand, “There is always hope a new
blockbuster will come out while we’re treating them.”
Experimental therapies further along in the testing
process continue to be made available to Oklahoma patients at OUCI in an expanding program of Phase II and
Phase III trials.
Members of the OUCI are actively involved in the
National Cancer Institute-sponsored cooperative group
programs, which focus on particular areas of cancer clinical research. The multidisciplinary, multi-institutional
programs conduct research across the country.
For example, the OUCI’s clinical trials program for
treating women’s cancers leads the nation in enrolling
patients within the Gynecologic Oncology Group, in
the search for new and better standards of care. (See
Page 25 for more on this pioneering effort.) The pediatric oncology program is another leader in clinical trial
participation through the Children’s Oncology Group
involving its young patients. OUCI’s medical oncologists participate in later-phase trials for breast, colorectal and prostate therapies through the Cancer and
Leukemia Group B program, and radiation oncologists
are offering trial opportunities to patients through the
Radiation Therapy Oncology Group.
“Phase III trials are what will ultimately change
your management of patients,” McMeekin said.
Pioneering
Change
in Women’s
Cancer Treatment
Joan Walker, M.D., George Lynn Cross Research Professor of Obsetrics and Gynecology
“I went to M.D. Anderson for a second opinion,
and they said, ‘Why are you here when you’ve already been to Dr. (Joan) Walker at OU?’ said Stage
3 ovarian cancer patient Joan Minks, Durant.
“They really recommended I go to OU because
I would have more and better treatment there
than I would have received at M.D. Anderson.”
Medical oncologists Shubham Pant, M.D., and Carla Kurkjian, M.D., look over the protocols for a Phase I drug trial.
And so this cancer patient, anxious for a way to prolong
her life, did what so many Oklahoma women before her
have done: she signed up for one of OU Cancer Institute’s
pioneering clinical trials that are changing the way
women’s cancer is treated.
OU’s gynecologic oncology program leads the nation in the number of enrollees in these trials through
the national Gynecologic Oncology Group, whether
for ovarian, uterine, endometrial, vulvar or cervical
cancer. Participation by Oklahoma women more than
equals the number of patients enrolled by the GOG
centers ranked 4 through 12.
“We are passionate about clinical trials,” said OUCI
Pioneering Change continued on page 28
[ FALL 2010 ]
PG. 25
RESEARCH
Personal
Finding a Cure
for Research Director
In his January 1971 State of the Union address, President Nixon declared
war on cancer: "I will also ask for an appropriation of an extra $100 million
to launch an intensive campaign to find a cure for cancer, and I will ask later
for whatever additional funds can effectively be used. The time has come
in America when the same kind of concentrated effort that split the atom
and took man to the moon should be turned toward conquering this dread
disease. Let us make a total national commitment to achieve this goal."
Danny N. Dhanasekaran, Ph.D., professor of cell
biology and director of basic science research for
the OU Cancer Institute, stands in front of a poster
showing the intricate web of cell signal transduction pathways implicated in the development of
cancer in humans.
When President Nixon declared war on cancer in 1971,
sequencing the genome for answers to the most arcane questions about how our bodies work was still three decades away.
It was only in 1972 that the term “signal transduction” – the
mechanism now considered key to personalized, targeted
treatment for cancer – first appeared in a scientific paper.
Over the next 38 years, much has been discovered about
the causes of cancer and how to fight it, but a cure for most
forms is still at least a decade or more away, according to
Danny N. Dhanasekaran, Ph.D., professor of cell biology and
deputy director for basic research for the OU Cancer Institute.
“When people ask me how much longer, I say, ‘10 years,’”
he said, smiling with the admission that he’s been saying “10
years” for the past decade.
A cure, or even treatments that extend life until a cure
can be found, can’t come too soon for people with cancer
and their loved ones. Dhanasekaran knows from personal
experience just how they feel.
Two years ago, Dhanasekaran saw his mother die of oropharyngeal cancer, “so I know what one goes through as a
family member. You feel helpless.”
Because of his position then as professor of biochemistry
at Temple University School of Medicine and principal investigator for its Signal Transduction Lab, Dhanasekaran had
the professional connections to know that clinical trials for a
“beautiful” new head and neck cancer drug were just two or
three years away when his mother died.
“I’d kept thinking, ‘If I can just keep her alive until I can
get her into trials.’
“Most of the things that went wrong to lead to her cancer. . . the pathway, the enzymes . . . are what I study in the
lab. And you think, ‘God, I work on this. Why can’t we find
the answers faster?’
“I’m so passionate about this because it’s personal.”
Finding a Cure continued on page 28
[ FALL 2010 ]
PG. 27
RESEARCH
Finding a Cure continued from page 27
Dhanasekaran joined the OU Cancer Institute in
March 2009 as holder of the Samuel Roberts Noble Chair
in Cancer Research with the goal of helping OUCI achieve
a critical mass of basic scientists and clinical researchers.
“The cancer institute here is on the cusp at this point.
There’s a very good clinical research group and very passionate basic laboratory research, but we need to ignite
this interaction more, and in order to do this, we need
more basic scientists.”
In addition to recruiting, Dhanasekaran is building
the research program by encouraging campus scientists
working on other diseases to apply relevant aspects of
their research to cancer as well.
Seed and other grants are being made available
through OUCI to make it financially possible for these
researchers to carve out a niche in their labs for cancer.
Grants are also being awarded to cancer researchers with
proceeds from a birthday party in 2009 honoring Oklahoma City banker, philanthropist and civic leader Gene
Rainbolt. A list of these awards and how the funds are
being used is on Page 29.
Dhanasekaran said most cancer research today is focused
on the development of new drugs and making recent drugs
even better by finding new targets for new therapies.
These targets are within the particular cell signaling
transduction pathway associated with a particular cancer. These pathways are communication routes for transmitting information between and within cells. Like electric
circuits made from molecules, pathways deliver such signals
as those that tell cells whether to multiply or die. Defects in
these pathways can lead to cancer.
Gleevec was the first targeted drug developed for cancer,
and it proved effective against chronic myelogenous leukemia by targeting an enzyme in a certain signaling pathway,
Dhanasekaran said.
But cancer is an elusive enemy, always finding a way to
evolve, perhaps by reemerging through another, still-untargeted pathway. “Now we’re finding genes with mutations
that are Gleevec-resistant, so a second-generation drug is
being developed that’s better than Gleevec.
“We can’t relax after finding a drug because, like in the case
of CML, cancer cells can find some way to survive.”
Dhanasekaran’s own research has been focused on Gprotein mediated pathways where lysophosphatidic acid, or
LPA, is the predominate growth factor driving the progression
of ovarian cancer.
“Our body routinely synthesizes this LPA molecule for
wound healing. It promotes cell growth, and that is what
happens when we have a cut. In ovarian cancer patients, this
growth factor is secreted, cancer cells have receptors for it,
and the cells start multiplying,” he said.
“We now know what can inhibit the signal before the
Cancer Scientists Receive Grants
The OU Cancer Institute has awarded the 2010 Cancer
Research Program Development Awards to five scientists studying prostate and ovarian cancer. The grants are
funded by donations collected during a birthday fundraiser honoring Oklahoma City businessman Gene Rainbolt.
Country music icon Willie Nelson performed.
Recipients are:
Ralf Janknecht, Ph.D.; Hsueh-Kung Lin, Ph.D.; Michael Ihnat, Ph.D., who are studying prostate cancer at
the molecular level to find new drug targets. They will
study in more detail how the interaction between ETV1
and JMJD2 affects prostate cancer cells and whether JMJD2
over-expression is an underlying cause of prostate cancer
development. The OU scientists hope the work will eventually lead to the development of a new drug class that can
be used in the treatment of advanced prostate cancer.
Joan Walker, M.D., and Kathleen Moore, M.D., with
other OUCI researchers will seek to identify biomarkers
for predicting response, prognosis, screening and early
detection of cancer, which can be incorporated into clinical care of women with gynecologic cancers. The proposed
studies will use three complementary approaches to iden-
tify biomarkers in ovarian, cervical and endometrial
cancers.
use. In March, Walker announced a new, three-arm trial
“that incorporates all of the things we know that improve
survival in ovarian cancer.”
Enrollment is under way in Oklahoma and nationwide
under Walker’s direction. She is lead investigator for a randomized trial that compares drugs and delivery methods
against each other to see which can deliver results that
take women beyond the expectation of five-year survival
and with the fewest side effects.
All three arms of the trial include bevacizumab, or
Avastin, to halt tumor angiogenesis, or the creation of the
growth of blood vessels which feed the tumor.
One arm uses IP delivery of both cisplatin and paclitaxel
and IV delivery of paclitaxel, which Walker said has shown
the best survival rate to date for women whose cancer was
totally removed through surgery: 68 months.
The two other arms contrast combinations of drugs –
including carboplatin instead of cisplatin, to reduce
side effects – and chemotherapy delivery techniques.
A second trial is underway for recurrent ovarian
cancer patients that compares a carboplatin-paclitaxel
regimen with the same combination plus Avastin.
The participation by patients like Minks in these
clinical trials is “selfless,” Walker said, as the women don’t
know which drugs they’ll receive. “It says who we are as
Oklahomans – more altruistic and giving to this world.”
Patients can enroll in trials for women’s cancers
through the OU Cancer Institute or with OUCI’s trial
partner in Tulsa, Cancer Care Associates. OUCI has
established a network to enable community oncologists throughout Oklahoma to enroll their patients
in clinical trials such as these and others and give all
Oklahomans access to the latest experimental drugs
and treatment plans.
OUCI Basic Cancer Biology Seed Grant Awards
have been awarded to:
Eric Howard, Ph.D., for a study of reciprocal
tumor-stromal interactions that reglate the mechanical properties of the tumor microenvironment.
Marie Hanigan, Ph.D., to develop inhibitors for a
protein that is expressed in many tumors and makes
them resistant to chemotherapy. The grant will provide funds to crystallize the protein, which will provide valuable information for further development of
the inhibitors. An American Cancer Society Institutional Research Grant Award went to:
Imad Ali, Ph.D., to perform adaptive prostate
brachytherapy, where volume enlargement by edema
and seed migration are considered in the seed implantation of patients with prostate cancer.
Finding a Cure continued on page 31
Pioneering Change continued from page 25
clinical trials director Scott McMeekin, M.D., himself a
gynecologic oncologist.
Among the world’s leading authorities on women’s cancer care is gyn-oncologist Joan Walker, M.D., George Lynn
Cross Research Professor of Obstetrics and Gynecology.
Walker has been a lead researcher in national studies that including optimizing the prevention of cervical
cancer by studying human papilloma virus vaccination
or management of abnormal pap tests of the cervix.
Another study that found laparoscopic surgical staging
for the treatment of uterine cancer is an effective and
safe alternative to open laparoscopy type surgery.
In 2006, she co-authored findings in the New England Journal of Medicine showing that flooding the abdominal cavity through intraperitoneal chemotherapy,
or IP, added 16 months to the lives of participants with
Stage III ovarian cancer.
The National Cancer Institute took the unusual step
of issuing a clinical announcement encouraging doctors
to use this new treatment, the first such announcement
since 1999. The urgency was prompted by the deadliness of
ovarian cancer. In Oklahoma, approximately 300 women
develop the disease annually, and more than half that
number die of recurrent cancer in less than five years. The
disease is dangerous because it often has no symptoms until
it has advanced and spread.
Walker said she assumed that IP chemotherapy with the
drug cisplatin would immediately become come the standard of care, “but it didn’t,” except at centers like OU’s.
Neither medical oncologists nor their patients liked it because of difficulties inherent in delivering IP chemotherapy
and the side effects from cisplatin.
So it was back to the drawing board for a therapy that
women can tolerate and that the medical community will
[ FALL 2010 ]
PG. 29
RESEARCH
Patterns May Lead to Early Detection
The peaks and valleys produced by mass spectocol,” says James Hocker, a researcher and colleague in
trometer analysis of blood drops are revealing
Hanas lab. “We are in the process of streamlining the
patterns that ultimately may offer the first-ever
procedure so it may be useful for hospital clinical labs.”
method for detecting lung cancer in its earliest
The payoff in lives saved by an early-detection
stages. Similarly, patterns also are being found in
method would be incalculable.
the blood of pancreatic cancer patients that could
The American Cancer Society's most recent estiresult in an early screening tool for this deadly
mates for lung cancer – the leading cause of cancer
cancer as well.
deaths in the United
Exhaustive comStates – show that
parisons of sera
about 219,440 new
profiles from cancer
cases were expected in
patients with pro2009 and that about
files of sera from
159,390 lung cancer pacancer-free voluntients would die. And
teers are giving
pancreatic cancer, the
researchers in the
fourth leading cause of
lab of Jay Hanas,
cancer deaths, is rarely
Ph.D., professor of
discovered early and
biochemistry and
has an overall five-year
molecular biology,
survival rate of less
a glimpse of the
than 6 percent.
The tall peaks at left in this graph show the presence of biomolecules
changes in blood
“The
concept
in the sera of people with late-stage pancreatic cancer. These peaks
components when
of
serum
profiling
do not appear in the sera of people without cancer. Identification of
these molecules could lead to detection of pancreatic cancer in its early
cancer is present.
comes from the hystages. A similar test could mean early detection of lung cancer as well.
Each
blood
pothesis that all of our
sample is processed
tissues and organs are
through equipment and computers sensitive
constantly shedding, sloughing off materials into our
enough to detect up to 80,000 “masses” of combloodstream,” Hanas explained. “The idea is that when
ponents in each tiny blood sample and produce
our physiology changes, like when we get a disease, the
a graph with as many peaks. The data obtained
patterns of these biomolecules being shed and secreted
from all samples is compressed to make the painsinto our blood stream are going to change.”
taking comparisons of peaks, valleys and slopes a
The challenge is in making sense out of all those
bit easier. Just one spreadsheet of data may have
tens of thousands of comparisons of the proteins, pepmore than 100 tabs.
tides, lipids, fatty acids, nucleic acids, glycoconjugates,
“At this stage it’s a complex and laborious pronucleotides and other components found in the blood
and then determining which are significant.
dures,” Hanas said.
Close examination of certain peaks reveals the tell “Any screening tool that results from his retale patterns in cancer patients that are different from
search will be especially helpful for such high-risk
those in people who are cancer-free. Hanas believes
populations as smokers and for example those with
the majority of
a family histhose peaks in the
tory of panblood of lung and
creatic cancer.
pancreatic cancer
“It’s not gopatients
repreing to replace
sent peptides, as
the CT scan,
he found in 2008
but a positive
with pancreatic
reading will
cancer patients,
give
physibut
the
molcians a headsecules in question
up on which
have not been
patients need
sequenced
for
to be moniidentification.
tored,
even
Just
being
if the CT scan
able to recogdoesn’t show
nize the patterns
anything.”
has meant 80 to
In perform90 percent efing their reficiency in the
search, Hanas
lab in declaring a
and
Hocker
Jay Hanas, Ph.D., professor of biochemistry and molecular biology, and lab colleague
James Hocker.
particular blood
work closely
sample to be
with surgeons
from a known lung or pancreatic cancer patient. To
Marvin Peyton, M.D., and Russell Postier, M.D.,
help validate their technology, Hanas and Hocker will
chair of the Department of Surgery, and their lung
test blood samples of patients who appear at the puland pancreatic cancer patients, plus Megan Lerner,
monology clinic with a nagging cough or other chest
assistant research professor, and Dan Brackett,
problem but no known lung cancer.
clinical research professor.
“We’ll do our (blood) tests to see whether we think
“These studies would not be possible without
they have early stage lung cancer and compare that
the strong support from the Department of Surto what happens as they go through diagnostic procegery,” Hanas said.
Finding a Cure continued from page 28
cells start multiplying,” Dhanasekaran said, adding that
a drug to do that is likely four or five years away.
Meanwhile, he is working with clinical trials director
Scott McMeekin, a gynecologic oncologist, to use elevated
LPA as a marker for early detection of ovarian cancer.
Ovarian cancer is called the “whisper killer” because its vague
symptoms are often overlooked until the cancer is in its later
stages.
“We don’t want to wait for a stage where it’s incurable,” Dhanasekaran said. “We’re looking for the pre-cancer stage to kill it.”
Forty years ago, when President Nixon announced the effort to find a cure for cancer, the commonly held belief was
that cancer was a single entity. Forty years of discovery have
revealed how mindboggingly complex a single tumor can be.
For Dhanasekaran, the job is to identify all the pieces and
keep the patient alive while the search continues.
“I said to my colleagues that if I could have kept my
mother alive for another three years, maybe I could have
given her a new drug. Until we find that drug, we have
to keep the patient alive.”
[ FALL 2010 ]
PG. 31
RESEARCH
New Drug Development
A Marathon, Not a Sprint
Bringing a new drug from concept to the market
Taking a drug from bench to bedside takes time, lots
takes about 20 years and $900 million. Not to mention
of time, time that many people with cancer – and those
the dead ends, delays and disappointments inherent in
at high risk for the disease – simply don’t have. In recent
the process of developyears, hyped news accounts
ing a drug, even one as
of SHetA2’s success in
promising as SHetA2.
shrinking a wide range of
Fortunately, the drug’s
tumors in test tubes and
developer, Doris Manmouse models reached
giaracina
Benbrook,
the international press
Ph.D., has plenty of paand resulted in a torrent
tience.
of phone calls and letters
Benbrook also has
from desperate cancer
the conviction that a
patients and their frantic
current National Cancer
loved ones. Each of them
Institute testing process
begged Benbrook for doses
will show SHetA2 to be
of her experimental drug,
every bit the cancerregardless that it is still not
preventer she believes
approved for humans and
it will be. Half-way
might be of little or no use
through tests for breast
to these particular patients.
cancer only, she was
“Look at this,” Benbrook
told the drug appeared
said as she removed the
to be effective. Critical
contents of an envelope
Phase I trials in humans
from Scotland that had
could be just a year or
arrived on her desk just
two away.
that morning. “I get so
Through a similar
many of these.” Inside was
NCI testing process, the
a photo of a middle-aged
drug – one in a class of
woman named Vivian, a
compounds called flexsmall landscape painting, a
ible heteroarotinoids, or
handmade chart detailing
Flex-Hets, has already
medical aspects of Vivian’s
Doris M. Benbrook, Ph.D., professor and director of research,
proven itself to be effeclosing battle with ovarian
Department of Obstetrics and Gynecology
tive in reducing growth
cancer and, finally, a plea
of kidney tumors.
for Benbrook’s drug.
Perhaps further tweaking can boost its power to kill
Within days came another plea, this time from a discancer in other organs from the 40 percent shown to
traught husband in France: “Doris, I ask you so much to
beyond the 60 percent level required to demonstrate
save Daniela's life. Please send the medicine! I will pay what
efficacy. Benbrook is hopeful the NCI will approve a
you want for it. I am so much desperated! If Daniela has to
new round of testing on a revised version of the drug.
die I will also finish my life.”
“It’s heartbreaking,” says Benbrook, who has temporarily ceased speaking to the news media about her research.
“Many of the callers are men who want the drug for their
wives. I have to tell them that I can’t give it to them. It
might be years away.”
The years for Benbrook and her drug now total 17. It
was in 1993 that she and K. Darrell Berlin, Ph.D., Oklahoma
State University Regents Professor of Chemistry, began
working to develop a cancer drug involving retinoic acid.
They started with a standard approach of developing a
drug that would target a particular molecule and inhibit its
contribution to cancer. In this case, the target was retinoic
acid receptors. Two problems with this strategy became obvious fairly early: making the compounds (by Berlin) and testing
each of them (by Benbrook) was too expensive, and targeting
just one molecule would be ineffective against cancer’s ability
to mutate and use other signaling pathways to grow.
So instead of focusing on a molecule she thought would
cure cancer, Benbrook looked to the cell itself and used a
cell-based assay to see which modified versions of the drug
had better killing power against cancer. Modifications continued until Benbrook and Berlin found the one they felt was
the most potent against cancer, but did not harm normal
cells. Ironically, the winner didn’t work through the pathway it was designed for. Structural modifications made to
eliminate toxicity meant it was no longer a retinoid.
Eight years had passed, and the Benbrook-Berlin team
was ready to publish their findings in The Journal of the
National Cancer Institute. However, publication required
showing the structure of their drug, and that couldn’t happen until the drug was patented. Another delay ensued
until a patent was applied for and received as a 50/50 partnership between OU and OSU.
Efforts to show not only that the compound worked,
but also why it worked, revealed that within 15 minutes of
treatment, the mitochondria in a cancer cells were swollen
and releasing molecules that prompted cell death. Nothing
similar happened in normal cells, “so we were able to define
that the drug induced an intrinsic apoptosis pathway to kill
cancer cells,” Benbrook said.
“It was very exciting, but I have a realistic point of view.
It’s easy to find evidence you have anti-cancer activity in a test
tube. And it’s easy to kill cancer in mice. I will not have that
‘Oh, my God!’ moment until I see a clinical trial where the
drug is actually working in a human.”
Her hope that this will happen lies with the NCI’s Rapid
Access to Prevention Intervention Development program, or
Marathon continued on page 36
William Hildebrand, Ph.D.,
Robert Glenn Rapp Presidential Professor of Microbiology
and Immunology.
T-Cell Vaccine
for Breast Cancer Possible
Perched on the surface of our cells are molecules that
give T-cells a sampling of what’s going on inside, from bits
of normal proteins to viral ones, if the cell is infected.
This key piece of the complex immunological interaction between T- and other cells is the focus of OU
research that seems likely to produce the first-ever
vaccines for several viral infections, including HIV,
plus tuberculosis and even cancer.
Already, a vaccine that triggers a T-cell assault
against West Nile virus has been created from this
research, and breast cancer cells have been killed in
animal models.
At the center of this study is that cell sampler, the
human leukocyte antigen molecule. HLA has been the
focus of study by microbiology and immunology professor William Hildebrand, Ph.D., for much of his career.
In 2000, Hildebrand developed a precise DNA test
T-Cell Vaccine continued on page 35
[ FALL 2010 ]
PG. 33
RESEARCH
T-Cell Vaccine continued from page 33
Gastroenterologist Courtney Houchen, M.D., has found a link between cancer and nonembryonic stem cells, which appear stained
on the computer monitor at right.
True Believer
A link between cancer and stem cells: religion or science?
One of the most contentious theories in cancer research today is that tumor development, growth and
metastasis can be blamed on cancerous, nonembryonic
stem cells. The fact that cancer recurs when standard
treatment stops is further evidence that stem cells are
behind the process, the theory’s proponents insist.
If this hypothesis is more religion than science, as
skeptics argue, then count physician-scientist Courtney Houchen, M.D., associate professor of medicinegastroenterology, as a true believer.
Houchen’s epiphany came when he was able to grow
new epithelial cells on the backs of nude mice. Here was
proof he had found a stem cell marker that allowed him to
distinguish stem cells from their ordinary offspring, isolate
them and use them to cause growth on those mice.
The link to cancer came when Houchen’s lab found
the same stem cell marker – DCAMKL-1 – expressed in a
variety of malignant tumors. Use of a reagent to block the
expression of RNA for this protein led to the discovery that
blocking DCAMKL-1 appears to reduce tumor growth in
the colon and pancreas.
“These data strongly suggested that this protein is
not only a marker of these stem cells, but likely plays
a key functional role in normal intestinal growth
and tumor progression,” Houchen said.
As a cancer stem cell marker, DCAMKL-1 could
eventually be a novel target for anti-stem cell-based
therapies for certain cancers, he added.
“We have advanced this stem cell research
through a lot of controversy,” Houchen said.
“When we first identified this marker, we thought it
was all pretty straightforward. This was (an area in
the colon) where stem cells are supposed to be, but
we had trouble getting it accepted by the scientific
community.
“We had to do many, many experiments to find
out the function of this protein so we could prove it
was involved in cancer and on normal stem cells.”
Houchen said it appears that the ability of stem
cells to promote several types of cell growth could
explain how cancer metastasizes.
Another characteristic of stem cells – that they
divide slowly – explains how they can avoid chemotherapy and radiation, which target rapidly dividing
cells, and survive to cause cancer to recur.
Houchen’s contribution to a recent increased interest in stem cells’ link to cancer also came in the
discovery by him and longtime former colleague,
Shrikant Anant, Ph.D., now at the University of
Kansas, of a second stem cell protein. This protein
turns off a natural tumor suppressor and turns on
a cancer-causing gene. It was the first evidence of a
stem cell protein’s regulation of a tumor suppressor.
Houchen, who holds the Frances and Malcolm
Robinson Chair in Gastroenterology, has recently
received grants of $192,215 from the Oklahoma
Center for Adult Stem Cell Research and $300,000
over three years from the Oklahoma Center for
the Advancement of Science and Technology to
continue his stem cell research. The OCAST grant
was matched by the VA Medical Center and ADNA
Inc. He and Russell Postier, M.D., chair of the Department of Surgery, have also received a National
Institutes of Health Exploratory/Developmental
Research grant of $382,000 from the National Cancer
Institute to study pancreatic cancer stem cells.
that became the standard method for comparing the
HLA of bone marrow and blood stem cell donors with
the HLA of transplant recipients and identifying the best
possible matches. Labs around the world offer variations
of this test, and Hildebrand’s lab continues to match
recipients with donors for the OU Cancer Institute’s
transplantation program and others.
The research to develop a vaccine also focuses on
HLA, the pieces of protein that HLA brings to the surface from both healthy and virus-infected or cancerous
cells, and how the immune system responds.
“We said, ‘If we find a particular thing that distinguishes the West Nile virus-infected cell or the breast
cancer cell from a healthy cell, can we make the immune system go after and kill the breast cancer or West
Nile virus-infected cells?’
“We took the pieces that distinguish those unhealthy
cells and built them into a vaccine,” Hildebrand said.
“We were able to show that we can indeed get the immune system to respond to that vaccine, then go and
kill the infected cell.
“We’re trying to be very systematic about it – what
target should we focus on and can we get the immune
system to go after that target? It’s very directed.”
Such vaccines would be priceless to people whose immune systems are less successful than other’s in fighting
off infection and cancer, whether the fault is with the
HLA molecule or with the immune system’s ability to
detect the problem.
With a vaccine, “instead of your having to make an immune
response, the immune response would be shot into you.”
Already, Hildebrand and his research colleagues have
shown they can destroy tumors in animal models with
vaccines that target breast cancer epitopes. A vaccine
against the West Nile virus was announced earlier this year.
“Now that we have demonstrated the feasibility of
developing a T-cell-specific vaccine, we intend to use
the same process to discover other reliable targets, validate them and develop additional vaccines.”
And there’s more: a comparison of breast cancer
cells with normal cells by then-graduate student Oriana
Hawkins, Ph.D., revealed that bits of protein in HLA can
also reveal whether the cancer is non-invasive or of an
invasive type that requires additional treatment.
Before a breast cancer vaccine is available, much more
research is needed to identify all of the possible targets
and to ensure that no healthy tissues would be affected.
[ FALL 2010 ]
PG. 35
SUPPORT
Marathon continued from page 33
RAPID, which can actually be quite slow. Nothing at all happened in the first year after Benbrook got word in 2006 that
her drug was accepted for testing as a breast cancer preventer.
RAPID began living up to its name in 2007, although
the process of proving prevention takes much more
time than the process for determining whether a drug
can shrink existing tumors. This preclinical testing
involves using a mouse model that develops breast
cancer. Half are treated with Benbrook’s drug. At a
certain point, the numbers of tumors that developed in
the treated and untreated groups are compared.
If the drug is statistically successful in repeated tests
and is not harmful, a request will go to the FDA for
approval of a Phase I toxicity study in three women per
dose level to determine the maximum tolerated dose.
Later Phase II trials would evaluate efficacy. Eventually,
a randomized Phase III trial would compare the results
with thousands of women receiving SHetA2 or the current
standard of care.
“(The prevention-testing process) is expensive because
you have to treat for a longer period of time and more patients are needed. In prevention, you’re treating someone
who doesn’t have cancer, so you can’t cause any toxicity.”
Meanwhile, Benbrook plans to return to the NCI with a
new proposal, this one to define the effectiveness of combining SHetA2 with a drug that activates cell death receptors in ovarian cancer.
Drug development is not a sprint but a marathon, Benbrook says. “It’s frustrating that it takes so long, but in the
process, I’ve trained a lot of people and there’s a lot of talent
coming out of my lab. If I fail, I’ll have a lot of progeny.”
Pawhuska High School student Ginny Horn accepts an award from First Lady Kim Henry in recognition of the school’s fundraising efforts, led by
members of Oklahoma Students Care. Also pictured are Kacie Bute, Tracey Scott and OU Cancer Institute Director Robert Mannel, M.D.
High School Students Join
Fight Against Cancer
Students at Edmond Memorial High School participated in dozens of crazy stunts and wound up smashing all fundraising records during its annual
Swine Week activities by raising more than $500,000 for the Jimmy Everest Center for Cancer and Blood Disorders in Children. Accepting the check
is Jimmy Everest, front row center, father of the late Jimmy Everest. On the back row are OU Health Science Center Provost Joseph J. Ferretti, Ph.D.,
left; Terrence Stull, M.D., chair of the Department of Pediatrics, center; and William H. Meyer, M.D., director of the Everest Center.
Some of the brightest medical and scientific minds in
the world have worked for decades to reduce the devastating impact of cancer on patients, families and, many
times, entire communities. The challenge may seem
overwhelming to many, but it hasn’t stopped Oklahoma
teenagers from joining the fight to prevent this terrible
disease and help those who have it.
Last year, high school students joined the new
Oklahoma Students Care program, initiated by the
OU Cancer Institute, to establish local cancer prevention programs and raise funds to assist cancer patients
throughout the state.
With youthful enthusiasm, energy and creativity, students from Durant to Pawhuska generated
Fight Against Cancer continued on page 38
[ FALL 2010 ]
PG. 37
RESEARCH
Fight Against Cancer continued from page 37
approximately $30,000 through Oklahoma Students
Care. Oklahoma First Lady Kim Henry, spokesperson
for the program, recognized high schools in Wilson,
Pawhuska, Byng and Oklahoma City in April at a Governor’s Mansion ceremony during which she thanked
the students, teachers and others at the four schools
for their hard work and the passion they brought to
the project.
A former public school teacher herself, Henry said
that many students, both individually and as members
of the various student councils and student bodies, are
eager to become involved and make a difference. Oklahoma Students Care offers them the perfect outlet.
“In its first year, I was impressed with how caring
and compassionate these students were,” Henry said.
“It makes me so proud of the next generation. There
are so many young people out there with big hearts.
Oklahoma Students Care is a great way for kids to
give back, to make a difference in something that has
touched their lives.”
At Pawhuska High School, the face of cancer has
been close and personal. One of their own – freshman
Ginny Horn, 15 – has been battling synovial cell sarcoma, a rare soft-tissue cancer that spread to her bones,
resulting in the amputation of a leg. To raise money
for Oklahoma Students Care, Ginny and her peers at
Pawhuska sold candy, sponsored a community carnival
and organized a rock-paper-scissors tournament.
As a show of solidarity, students held a formal attire day at school where they exchanged their jeans,
T-shirts and sneakers for tuxedos and dazzling dresses.
For Ginny, it was the prom she feared she might never
attend. Happily, she shared the real prom with her
schoolmates later in the semester.
“I was impressed with how a simple thing like
wearing a prom dress to school can have such a lasting
effect,” Henry said.
While Henry cited Ginny’s story as the most poignant, she expressed excitement, though not surprise,
at the enthusiasm with which all of the participating
schools tackled their fundraising goals.
Through their involvement in this project, she
said, the students acquire a better awareness and understanding of cancer. Beyond that, they gain something even greater: a sense of empowerment, an understanding that they can make a difference in society,
even before they pick up their diploma, she said.
Wilson High School, the first school to participate in the
program, hosted a “pink-out” football game against rival
Velma-Alma, and both schools have agreed to make the
program an annual event. Next fall, Velma-Alma will host.
Byng High School students challenged teachers to various
“dares,” like eating a bug, if the students raised certain levels of money.
Oklahoma City’s Heritage Hall raised the largest amount
of funds for the program, $12,000, by auctioning the best
parking spaces at the school, including the principal’s spot;
selling doughnuts and T-shirts; and hosting a date party at
the school.
Henry is excited about the direction the program will
take in the future. With one year of success behind them,
she said, students across the state – with the full-hearted
support of scores of teachers, principals and other school
administrators – are planning a host of exciting projects.
“I am pleased to be asked to continue to work with
Oklahoma Students Care, and I hope that this project will
continue to gain momentum for many years,” Henry said.
What lies in store for this innovative new program?
One new development is a collaboration between Oklahoma Students Care and the Oklahoma Secondary School
Activities Association, which administers athletic and
other competitions across the state. The OSSAA helped
encourage schools to do “pink out” events for all athletic
events during Win-Win Week, Sept. 13 - 17. Football, fall
baseball, volleyball, fast-pitch softball and cross country
teams joined cheerleaders, pom squads, marching bands,
student councils, leadership classes and other student organizations in myriad activities.
OU Heisman Trophy winners Steve Owens, Billy Sims and
Jason White helped the First Lady promote Win-Win Week.
“We are pleased to build on last year’s success with
Oklahoma Students Care. Students are helping to raise a
healthier generation of Oklahomans by reducing the incidences of cancer, and at the same time, they are providing
essential programs to support a variety of patient needs,”
said Robert S. Mannel, M.D., director of the OU Cancer
Institute.
“During Win-Win Week, Oklahoma was the first state in
the nation to galvanize all schools of the state as a way of
improving the lives of cancer patients. We know that this
generation can be the generation that helps win the war on
cancer in our state.”
Leadership Council
The OU Cancer Institute Leadership Council provides counsel to the administration of the institute and
helps open doors to major donors, company boardrooms
and government leaders. Hoping to secure philanthropic
and other funding is a primary function of this group.
Members are also counted on to raise awareness of the
mission of the OU Cancer Institute and encourages others
to support its efforts.
Christy Everst, chairman and CEO of the Oklahoma
Publishing Co., is the first chair of the Leadership Council.
Her fellow founding members are her husband, Jim
Everest, and Gene Rainbolt, Rick and Jennifer Dunning,
Nancy Moore, Rainey Williams, Scott Meacham and
Mike Samis, all of Oklahoma City, and Sandy Kinney,
chair of the Board of Advocates, Norman.
Board of Advocates Members Are
Statewide Ambassadors for OUCI
Clockwise from top right:
Members of the OU Cancer Institute Board of
Advocates come from all walks of life and all
corners of the state, as the map indicates. Members
provide outreach opportunities for OUCI in their
communities and a local connection for those who
might seek treatment.
Sandy Kinney, Norman,
chair of the Board of
Advocates, welcomes participants to a spring kickoff meeting for the group.
OU Cancer Institute Board of Advocates member
Sheppard F. “Mike” Miers of Tulsa, left, and
OUCI deputy director for basic research Danny
Dhanasekaran, Ph.D., share a table at an OUCI Board
of Advocates meeting.
[ FALL 2010 ]
PG. 39
E D U C AT I O N
Oregon Health & Science UPortland, Ore.
Yaohan “Adrienne” Li
OU College of MedicineP Oklahoma City
OU College of MedicineOklahoma City
Todd Mollet
OU College of MedicineP Oklahoma City
OU College of MedicineOklahoma City
EMERGENCY MEDICINE
Brandon BrownOU College of MedicineTulsa
Keith FischbornOU College of MedicineTulsa
Korby PogueOU College of MedicineTulsa
Eric ReddickOU College of MedicineTulsa
Adam Rowe
U of Alabama Medical Center
Birmingham, Ala.
Philip Sloan
Synergy Medical Education Alliance
Saginaw, Mich.
Christine Swenton
U Florida College of Medicine
Jacksonville, Fla.
Kaylan Lawson, left, and her sister, Whitney, couldn’t be more excited about Kaylan’s match with the OU College of Medicine and the Oregon
Health and Science University for her dermatology training. Matches were revealed on the labels of wrapped wine bottles distributed to the Class
of 2010 during a luncheon at Gaillardia Country Club.
Where Is the
Class of 2010 Now?
The following list shows the specialties chosen by members of the Class of 2010 and where their residency training
will be held.
ANESTHESIOLOGY
Raymond Azadgoli
OU College of Medicine
Oklahoma City
Ryan Butterworth
Emory U. School of MedicinePAtlanta
Emory U. School of MedicineAtlanta
Cassandra Duncan-Azadi
OU College of MedicineP Tulsa
U Alabama Medical CenterBirmingham, Ala.
Joshua GoreOU College of MedicineOklahoma City
Jeremy HaneyOU College of MedicineOklahoma City
John Patzkowsky
University Hospitals Case Medical Center
Cleveland, Ohio
Tyler Suchala
Wayne State U/Detroit Medical Center
Detroit
John YoungOU College of MedicineOklahoma City
DERMATOLOGY
Logan D’Souza
U Connecticut Health CenterPFarmington, Conn.
U Connecticut Health CenterFarmington, Conn.
Kaylan Lawson
OU College of MedicineP Oklahoma City
GENERAL SURGERY
Brad Bennett
U of TennesseeP Chattanooga
Luke ElmsOrlando HealthOrlando
Jesicah Gilmore
OU College of MedicineP Tulsa
Jacqueline Teddi Lee
Northwestern McGaw/Memorial Hospital/VA
Chicago
Paul Long
Texas A&M-Scott & White
Temple, Texas
Nathan VaughanBaylor U Medical CenterDallas, Texas
Timothy WeaverOU College of MedicineOklahoma City
Ryan WicksOU College of MedicineOklahoma City
Jessica Zaman
Wayne State U/Detroit Medical Center
Detroit
FAMILY MEDICINE
Serena Anderson
Integris Baptist Medical Center
Oklahoma City
Mary AspyOU College of MedicineOklahoma City
Shikha Bhan
Aurora St. Luke’s Medical Center
Milwaukee
Meagan BradyOU College of MedicineTulsa
Jason Breed
Integris Baptist Medical Center
Oklahoma City
Riana Cooper
Integris Baptist Medical Center
Oklahoma City
Kristie CraigSW Oklahoma Family MedicineLawton
Jason DeckOU College of MedicineOklahoma City
Holly GorackeSt. Anthony HospitalOklahoma City
Aubrey Kavanaugh
Integris Baptist Medical Center
Oklahoma City
Jeffrey LawrenceSt. Anthony HospitalOklahoma City
Melanie Marshall
OU College of Medicine
Oklahoma City
Joseph NguyenOU College of MedicineOklahoma City
David Jordan Paslay
Ventura County Medical Center
Ventura, Calif.
Tanya PutnalOU College of MedicineTulsa
Joshua ReeseProvidence Milwaukie HospitalMilwaukie, Ore.
Jesse SamuelSt. Anthony HospitalOklahoma City
Nicholas SloatSt. Anthony HospitalOklahoma City
Jana Smith
U Arkansas Medical Sciences
Fayetteville, Ark.
Sheleatha Taylor-Bristow
Integris Baptist Medical Center
Oklahoma City
Sean TuckerSt. Anthony HospitalOklahoma City
Catherine TungResearch Medical CenterKansas City, Mo.
Michelle Ward
U Texas Health Sciences Center
Tyler, Texas
INTERNAL MEDICINE
Luke Cunningham
Jacob Doyle
Namali Fernando
Dustin Fravel
Baylor College of Medicine
Houston
OU College of MedicineP Tulsa
OU College of Medicine
Oklahoma City
OU College of MedicineP Tulsa
[ FALL 2010 ]
PG. 41
E D U C AT I O N
Chase Hendrickson
Yale-New Haven Hospital
New Haven, Conn.
Matlock JeffriesOU College of MedicineOklahoma City
Andrew John
OU College of MedicineP Tulsa
Lauren LaBryerOU College of MedicineOklahoma City
Kurian Thomas Maliel
San Antonio Military Medical Center
San Antonio
Ryan Mascarenhas
Washington Hospital Center
Washington, D.C.
Jonathan Miner, Ph.D.Barnes-Jewish HospitalSt. Louis
Patrick NorrisOU College of MedicineTulsa
Sarah RiceNaval Medical CenterSan Diego
Rebecca Stormont
Creighton University Affiliated Hospitals
Omaha, Neb.
Lydia Sutherlun
Texas A&M-Scott & White
Temple, Texas
Horace Tang
U Massachusetts Medical School
Worcester, Mass.
Janice TeOU College of MedicineOklahoma City
MEDICINE-PEDIATRICS
Bradley BurgetOU College of MedicineOklahoma City
Joseph GhataOU College of MedicineOklahoma City
Michael Kleinman
U Tennessee College of Medicine
Memphis, Tenn.
NEUROLOGY
Aaron FarrowOU College of MedicineOklahoma City
Travis GarrettBaylor College of MedicineHouston
Mitch HargisBaylor College of MedicineHouston
Andrew Hong
U Iowa Hosp.& ClinicsPIowa City, Iowa
U Iowa Hosp.& ClinicsIowa City, Iowa
Jobria McCracken
Emory U School of Medicine – transitional
Atlanta
Emory U School of MedicineAtlanta
Brooke McQueen
Methodist Hospital – transitional
Houston
Methodist HospitalHouston
Christi Pendergraft
OU College of Medicine
Oklahoma City
Justin Rousseau
St. Mary Medical CenterPLong Beach, Calif.
UC San Diego Medical CenterSan Diego
NEUROSURGERY
Daniel HarwellUniversity HospitalCincinnati, Ohio
Kristopher Kimmell
U Rochester/Strong Memorial
Rochester, N.Y.
OBSTETRICS-GYNECOLOGY
Autumn ElmsOrlando HealthOrlando, Fla.
Caroline FlintOU College of MedicineOklahoma City
Thomas Lance Lane
Texas A&M-Scott and White
Temple, Texas
Gwendolyn Neel
Louisiana State U. Health Sciences Center
Shreveport, La.
Blake Porter
U Alabama Medical Center
Birmingham, Ala.
Christa ThomasOU College of MedicineOklahoma City
Eric ThomasOU College of MedicineOklahoma City
OPHTHALMOLOGY
Alan Hromas
U Missouri-KC ProgramsPKansas City, Mo.
U Kansas- Kansas CityKansas City, Kan.
Blake Isernhagen
OU College of MedicineP Oklahoma City
OU College of MedicineOklahoma City
ORTHOPEDIC SURGERY
Matthew BauerNaval Medical CenterSan Diego
Jeffrey Belisle
San Antonio Military Medical Center
San Antonio
Kristopher Collins
U South Florida College of Medicine
Tampa, Fla.
Blake Porter and his wife, Kendall, are all smiles about his match with the University of Alabama Medical Center, Birmingham, for his
obstetrics and gynecology training.
Zachariah Logan
U Florida College of Medicine
Jacksonville, Fla.
Ryan Odgers
Banner Good Samaritan Medical Center
Phoenix
OTOLARYNGOLOGY
Tyson Fisher
Wayne State University School of Medicine
Detroit
Brandon PiersonOU College of MedicineOklahoma City
PATHOLOGY
Adam Hoffhines, Ph.D.
U Texas Southwestern Medical School
Dallas, Texas
PEDIATRICS
Allyson BlackOU College of MedicineOklahoma City
Gopal ChandrasekharanOU College of MedicineTulsa
Lauren ChastainOU College of MedicineOklahoma City
Jared CordellOU College of MedicineOklahoma City
Lori CrowOU College of MedicineOklahoma City
Amy D’AngeloChildren’s Mercy HospitalKansas City, Mo.
Sheila Donovan
St. Louis University School of Medicine
St. Louis
Reed EversU Rochester/Strong MemorialRochester, N.Y.
Erica FaulconerOU College of MedicineOklahoma City
Emmy Garber Baird
OU College of Medicine
Tulsa
Amy Gumuliauskas
OU College of Medicine
Oklahoma City
Adam HannaOU College of MedicineOklahoma City
Amanda MartinU ArkansasLittle Rock, Ark.
Brittany Radcliffe
Rush University Medical Center
Chicago
Shawndip Sen
NYP Hosp.-Columbia U Medical Center
New York
Carrie SpielmanChildren’s Mercy HospitalKansas City, Mo.
Julia StoltenbergOU College of MedicineOklahoma City
[ FALL 2010 ]
PG. 43
E D U C AT I O N
TULSA
Jason VanderLugt
Grand Rapids Medical Education
Grand Rapids, Mich.
Misty WoodwardOU College of MedicineTulsa
PLASTIC SURGERY
Aaron Morgan
OU College of MedicineP Oklahoma City
OU College of MedicineOklahoma City
PSYCHIATRY
Melanie Barrett
U North Carolina Hospitals
Chapel Hill, N.C.
Shyvonne Brooke
OU College of Medicine
Oklahoma City
Jordan Cates
U Iowa Hospitals and Clinics
Iowa City, Iowa
Rachel DalthorpOU College of MedicineOklahoma City
Benjamin HidyUC Davis Medical CenterSacramento, Calif.
Jessica JonesOU College of MedicineTulsa
Libby PeekBarnes-Jewish HospitalSt. Louis, Mo.
Laura SmithOU College of MedicineOklahoma City
Mary Turner
Oregon Health & Science U
Portland, Ore.
Zafar ZaidiOU College of MedicineTulsa
PSYCHIATRY-FAMILY MEDICINE
Matthew Morris
U Iowa Hospitals and Clinics
Iowa City, Iowa
RADIOLOGY
Jonathan Chris Cross
OU College of MedicineP Oklahoma City
Integris Baptist Medical CenterOklahoma City
Ryan Hurst
OU College of MedicineP Oklahoma City
Integris Baptist Medical Center Oklahoma City
Newton Neidert
Colorado Health Foundation – transitional
Denver
Mayo School of Graduate Med. Ed.
Rochester, Minn.
Geoffrey PaddackU ArkansasLittle Rock, Ark.
Matthew TowsleyU of MissouriKansas City, Mo.
Lauren Tribbey
Texas A&M-Scott & White
Temple, Texas
Craig White
OU College of MedicineP Oklahoma City
OU College of Medicine
Oklahoma City
SURGERY
Patrice Janell Holmes
U South CarolinaPGreenville, S.C.
Michael Slade Stratton
Navy Medical Center
Portsmouth, Va.
UROLOGY
Kathryn Griffin
U Texas Medical SchoolPHouston
U Texas Medical SchoolHouston
Kirsten Janosek-Albright
Henry Ford HSCPDetroit
Henry Ford HSCDetroit
Mohammad Ramadan
OU College of MedicineP Oklahoma City
OU College of MedicineOklahoma City
Timothy SuttleU of ToledoToledo, Ohio
Eric Wisenbaugh
Mayo School of Graduate Med. Ed.P
Scottsdale, Ariz.
Mayo School of Graduate Med. Ed. Scottsdale, Ariz.
VASCULAR SURGERY
John WeberCleveland Clinic FoundationCleveland, Ohio
P
- Preliminary – 1-2 years of prerequisite training
David Kendrick, M.D., assistant provost for strategic planning and director of medical informatics at the OU School of Community Medicine,
talks with Kim Crosby, Pharm.D., OU-Tulsa, about the planned health information network. Photo by Tom Gilbert courtesy of the Tulsa World.
12 Million
$
for Health Info Network Awarded to Tulsa
A planned health information network linking
11 counties and led by David Kendrick, M.D., MPH,
chief of the Division of Medical Informatics at the
OU School of Community Medicine, has received a
$12 million federal stimulus Beacon Community grant
to to improve health outcomes in the Tulsa region.
Kendrick, coordinator for the Greater Tulsa
Health Access Network, or Greater THAN, said,
”Our community will now have the resources to
build a new infrastructure to support a highly effective health care system we need to improve the
health of our entire community.”
Kendrick said three main areas make up the ef-
fort: a highly secure, confidential information exchange
between hospitals and clinics so data on patients will be
where it is needed, better coordination of health care and
improved decision-support for patients.
By linking health care providers in the 11 counties, duplicate tests and medical errors will be averted and patients
will have instant access to their own medical records.
Tulsa was one of 15 communities selected from a pool
of 137 applicants. In announcing the winners, the Obama
administration cited Oklahoma’s “epidemic” of obesity
and diabetes and its high rate of cardiovascular disease as
indicators of need, as well as the high level of innovation in
$12 Million continued on page 47
[ FALL 2010 ]
PG. 45
TULSA
$12 Million continued on page 45
Ground Broken
for Tisdale
Specialty Center
Right: Regina Tisdale, widow of former Sooner and NBA basketball star
Wayman Tisdale, helps her granddaughter, Bailey Braxton, turn the dirt
at groundbreaking for the OU Wayman Tisdale Specialty Health Center
on Tulsa’s North Side. Wayman Tisdale was 44 when he died in May 2009.
Above: Family members and friends of the late basketball great Wayman Tisdale join OU officials in breaking ground for the OU Wayman
Tisdale Specialty Health Center in North Tulsa. Tisdale’s widow, Regina, is in the center of the photo; at her left is OU President David L.
Boren. OU-Tulsa President Gerard Clancy, M.D., is fifth from left. Wayman Tisdale, who died in May 2009, was an All-American with the
Sooners before joining the National Basketball Association and a jazz musician.
the Tulsa proposal as demonstrating potential success.
“These pioneering communities are going to lead the
way in bringing smarter, lower-cost health care to all
Americans through use of electronic health records,” Vice
President Joe Biden said in a news release.
“Because of their early efforts, doctors across the country
will one day be able to coordinate patient care with the
stroke of a key or pull up life-saving health information
instantly in an emergency – and for the residents of these
communities, that future is about to become a reality.”
Singling out Tulsa for its innovative approach to improving
health outcomes and its broad-based coalition, the announcement said the award will help 1,600 physicians and other providers participate in a new health information system. The
system is expected to save $11 million in costs yearly through
reductions in preventable hospitalizations and emergency
room visits and increases in appropriate screenings and use of
telemedicine, according to administration predictions.
Kendrick has said the savings may be even greater. A 2006
research study conducted in the Tulsa region by the Harvard
Center for IT Leadership has estimated that the system would
save about 420 lives from adverse drug reactions and more than
$200 million a year in costs. The study, sponsored by the George
Kaiser Family Foundation, estimated the savings from avoided
duplication of lab tests, imaging studies and decreased unnecessary hospitalizations.
Paramedics who are dealing with an unconscious person
and emergency departments that are otherwise “flying
blind” in treating severely injured accident victims will
have immediate access to data about these patients’ allergies and other vital medical information.
The Greater THAN project brings together key health
providers in the Tulsa area, many of whom are competitors, to work together to improve health in the region.
Steve Dobbs, chief executive officer of Hillcrest Medical
center, said the grant and resulting health information
network will “catapult us ahead of the nation in quality,
outcomes and lowering prices.”
OU School of Community Medicine Dean Daniel Duffy,
M.D., noted that Kendrick collaborated with about 300 health
care leaders in the area to write the grant application with the assistance of Joe Walker, director of operations for Greater THAN.
This effort is a prime example of the type of work that the
OU School of Community Medicine was intended to do. By
acting as a convening agent, OU served a key role in uniting
competing stakeholders to raise the quality and efficiency of
health care for an entire community,” Duffy said.
Tipton Named Chair
of Family Medicine
OU College of
Medicine alumnus
John W. Tipton, ’72
M.D., is the new chair
of the Department
of Family Medicine
of the OU School of
Community Medicine in Tulsa.
An
Oklahoma
native, Tipton also
earned his underJohn W. Tipton, M.D.
graduate
degree
from OU. He interned in Oklahoma City before completing a family
medicine residency in 1975 at St. Joseph's Hospital in
Wichita, Kan. He then served two years in the Air
Force, where he helped develop a family medicine
clinic and residency program at Carswell Air Force
Base.
“John Tipton is an outstanding teacher, physician
and administrator, and we are delighted he was willing to chair a department with such an important
role in our community care mission,” said thenDean Gerard Clancy, who named Tipton to the post.
Clancy is president of OU-Tulsa.
As one of the first residency-trained family physicians in Tulsa, Tipton had a solo practice until 1994,
when he entered full-time teaching as associate professor in the Department of Family Medicine. In his first
year as a faculty member, his students honored him
with the Aesculapian Award for outstanding teaching.
Tipton was family medicine/emergency medicine
fellowship director from 2006 to 2007 and had been
vice chair of the department since 2004. He has been
chief of the family medicine section at Hillcrest Medical Center since 2007.
Tipton is active in Boy Scouts and his church
and enjoys sailing, snow skiing and scuba diving.
His favorite activity is spending time with his wife
and six children.
[ FALL 2010 ]
PG. 47
F A C U LT Y N E W S
Awards Presented At Spring Meeting
Regents’ Awards for service and teaching were presented by Regent John Bell, M.D., to C. Douglas Folger,
M.D., Sanjay Bidichandani, Ph.D., and David C. Kem,
M.D., at the spring faculty awards meeting in April.
Folger received the award for superior professional and
university service and public outreach. He is associate
dean for clinical affairs and medical director of OU Physicians. Bidichandani, associate professor of biochemistry
and molecular biology, received the award for superior
teaching. He is assistant dean for preclinical curriculum.
Kem, George Lynn Cross Research Professor of Endocrinology, was recognized with a Regents’ Professorship.
OU President David L. Boren announced the awarding
of a David Ross Boyd Professorship to Russell G. Postier,
M.D., chair of the Department of Surgery. Named George
Lynn Cross Research Professor was Judith James, M.D.,
Ph.D., professor of rheumatology, immunology and allergy.
Boren awarded Presbyterian Health Foundation Presidential Professorships to Madeleine Cunningham, Ph.D.,
George Lynn Cross Research Professor of Microbiology and
Immunology, and Daniel J.J. Carr, Ph.D., professor of ophthalmology. Mark Wolraich, M.D., professor of pediatrics
and director of the OU Child Study Center, was presented the
Edith Kinney Gaylord Presidential Professorship by Boren.
OU Health Sciences Center Provost Joseph J. Ferretti,
Ph.D., awarded the Provost’s Research Award to Junior Faculty to Mark L. Lang, Ph.D., assistant professor of microbiology and immunology.
Named by OU Regents to endowed faculty positions are
Martin Allan Turman, M.D., professor of pediatrics, to the
Paul and Ann Milburn Chair in Nephrology; R. Michael
Siatkowski, M.D., professor of ophthalmology, to the James P
Luton Chair in Ophthalmology; and Wayne C. Drevets, M.D.,
professor of psychiatry at the School of Community Medicine,
to the Oxley Foundation Chair in Neuroscience Research.
honored by the Christie
Society for his teaching
contributions in 1994,
with the Brittingham
Award as the outstanding
clinical teacher in 1995,
and named the outstanding physician and role
model by the Department
of Pediatrics in 1996. At
the time of his death, he
was professor emeritus of
Harris D. Riley Jr.
pediatrics.
The Harris D. Riley, Jr.
Pediatric Society sponsors an annual lecture at Children's
Hospital of OU Medical Center in his honor.
28 at his home in Afton. He was 66. A graduate of the Duke
University Physician Assistant Program, he was the first PA
hired by the Mayo Clinic in Rochester, Minn. Godkins also
received a master of public health degree from OU. He was
associate director of the College of Medicine’s PA program
and continued to serve on the PA admissions committee
and to teach the history of the profession after becoming a
university administrator.
Three Department of Family and Preventive Medicine
faculty members were honored by the Oklahoma Academy
of Family Physicians in June. Steven Crawford, M.D., chair
of the department, received the 2010 Family Physician of the
Year Award. He is a past president of OAFP and current co-chair
of its legislative committee. James Brand, M.D., professor of
family medicine, was recognized by OAFP for his commitment
and service to the American Academy of Family Physicians by
the the Accreditation Review Commission on the Education of
the Physician Assistant. He is a past OAFP president. Jackie
Durrett, M.B.A., clinical assistant professor and department
manager, received the OAFP Friend of Family Medicine Award
in recognition of his advocacy of family medicine.
The father-son duo of John F. Tompkins, M.D., associate professor of orthopedic surgery, and S. Fulton
Tompkins, M.D., former clinical professor of orthopedic
surgery, have coauthored the book, An Ounce of Prevention.
Chapters provide basic facts about organ systems and diseases, plus answers to the most asked questions on these
topics. OU faculty members are among the experts who
provide the answers.
Donald R. Stout, M.D., instrumental in developing
the Department of Obstetrics and Gynecology in the college’s Tulsa branch and hiring the school’s first dean, was
awarded a Regents’ Alumni Award at ceremonies in May.
He served as a clinical faculty member for many years.
In Memoriam
Harris D. Riley Jr., chair of the Department of Pediatrics from 1958 until his retirement in 1991 as Regents’
Distinguished Professor of Pediatrics, died March 26 in
Nashville, Tenn. He was 85.
At 32, he became the youngest chair of a major
medical department in the country when appointed
to the OU post. He recruited a talented faculty, attracted national grants and recognition, was a prolific
researcher and writer, trained countless pediatricians
and oversaw a major addition and renovation of what is
now the “old” Children’s Hospital.
Riley grew up in Tupelo, Miss., graduated from
Vanderbilt University in 1945, served in the U.S. Navy
and Air Force and graduated from Vanderbilt Medical
School in 1948. He interned at Johns Hopkins Hospital
and completed his residency at Case Western Reserve
Children’s Hospital. He returned to Vanderbilt where
he served until his appointment to OU.
In 1992, Riley returned to Vanderbilt as a professor
of pediatrics and continued to teach, care for children
and lead the Amos Christie Scholars program. He was
Thomas R. Godkins, former assistant provost, director
of capital planning and associate vice provost for facilities
management for the OU Health Sciences Center, died June
Maternal-fetal medicine specialist Glenn Lee Haswell,
M.D., obstetrics and gynecology faculty at the OU College of Medicine-Tulsa, died June 30 in Tulsa. He was 69.
Haswell established the maternal-fetal program at St. John
Medical Center. He retired in 2005.
Malcolm Robinson, ’68 M.D., former clinical professor
of medicine and founder, president and a medical director
of the Oklahoma Foundation for Digestive Research, died
June 5 at 67. In honor of his parents, he established the
Frances and Malcolm Robinson Chair in Gastroenterology held by Courtney Houchen, M.D. Robinson’s
post-graduate medical training was at the Cleveland
Clinic Foundation, OU College of Medicine and Duke
University with a NIH-funded GI research fellowship.
He also served three years as a research gastroenterologist in the neuropsychiatry division at Walter Reed
Institute of Research. In 1995, he received the Janssen
Award for achievement in clinical gastroenterology.
Robinson lived in Sarasota, Fla.
Theresa Stacy Williams, ’65 M.D., professor emeritus of radiological services, died July 31 at 79. She
lived in Guthrie. Williams worked at the OU Health
Sciences Center as a registered nurse while earning the
educational credits to enter the OU College of Medicine in 1961. The pediatric radiologist was recipient of
the Regents’ Award for Superior Teaching. She retired
in 1992.
[ FALL 2010 ]
PG. 49
F A C U LT Y N E W S
Edgar Young Award
to Chittur Sivaram
CLASS NOTES
Class Notes
50s
Chittur A. Sivaram, M.D., David Ross Boyd Professor of Medicine, received the 2010 Edgar W. Young
Lifetime Achievement Award and the Aesculapian
Award from the Class of 2010 during the annual spring
Aesculapian Banquet.
Sivaram is vice chief of the cardiovascular section and
recipient of numerous teaching awards, including Aesculapian Awards from second-year classes for pre-clinical
training in 2006 and 2007 and the Department of Medicine’s
outstanding physician-teacher award in 1996.
In 2007, he received the Regents’ Award for Superior
Teaching, and he was recognized in 2008 with prestigious
designation as a David Ross Boyd Professor.
Sivaram has served his profession as governor of the
Oklahoma Chapter of the American College of Cardiology.
The Young Award was established in 1987 by the Medical
Student Council in honor of its first recipient to recognize
long-term dedication to medical education.
Recognized with Aesculapian Awards for teaching the
basic sciences were Kennon M. Garrett, Ph.D., associate
professor of physiology, by the Class of 2013, and Michael
A. Ihnat, Ph.D., assistant professor of cell biology, by the
Class of 2012.
Residents recognized with Aesculapian Awards by the
Class of 2011 in Oklahoma City and Tulsa, respectively,
were Michael W. Roberts, M.D., surgery, and Jason Beaman, D.O., Family Medicine.
Full-time
faculty
physicians recognized by
the Class of 2010 in Oklahoma City and Tulsa,
respectively, were Sivaram
and Chandini Sharma,
M.D., assistant professor of
geriatrics. Volunteer faculty members recognized
by the Class of 2010 in
Oklahoma City and Tulsa,
respectively, were Bill
Bondurant, M.D., family medicine, and Edwin
Chittur A. Sivaram, M.D.
Yeary, M.D., surgery.
Robert Engles, ’54 M.D., has retired from his general
surgery practice in Durant. He is the medical director
of four Bryan County nursing homes.
Helen Sue White Hathaway, ’54 M.D., lives in Denver
and is retired from her pediatrics practice.
Jim Blevins, ’55 M.D., is retired and lives in Campbell,
Calif. He practiced addiction psychiatry and was chief
of chemical dependency services at Kaiser Medical Center in Santa Clara.
Orby L. Butcher Jr., ’55 M.D., lives in Shawnee and is
active in disaster relief ministries with the Baptist General Convention of Oklahoma and with the Oklahoma
Disaster Relief Medical Reserve Corps.
David D. Paulus, ’55 M.D., a diagnostic radiologist,
retired in 1992 from the University of Texas M.D. Anderson Cancer Center, where he still consults. He lives
in Houston.
Ernest G. Shadid, ’55 M.D., retired in 2005 from Griffin
Memorial Hospital in Norman, where he served as the
director of the psychiatric residency training program.
His three sons also are psychiatrists, and his daughter is
a psychiatric social worker.
Cranfill Karl Wisdom, ’55 M.D., has retired after practicing radiology for 30 years. He lives in Shawnee.
Ralph G. Sablan, ’59 M.D., lives in Agana, Guam, and
practices dermatology parttime. He is a founding director of the Bank of Guam.
60s
Virgil R. Jobe, Jr., ‘60 M.D., is staff radiologist at Straub
Clinic and Hospital in Honolulu and has been a member
of the clinical faculty at University of Hawaii John A.
Burns School of Medicine in Honolulu since 1975.
Stan Muenzler, ’60 M.D., practices ophthalmology in
Oklahoma City. He is also medical director of Okla-
homa Lions Eye Bank and a clinical professor with the OU
Department of Ophthalmology.
practiced diagnostic radiology at VA Medical Center in
Denver and retired from the U.S. Army in 2008.
Edward A. Shadid, ’60 M.D., specializes in plastic surgery
in Oklahoma City. He is in practice with his son, Derek,
‘99 M.D., and also works with his son, Chris, ’00 M.D., an
anesthesiologist.
Peter Carryer, ’75 M.D., resides in Rochester, Minn.,
where he has been on the gastroenterology staff for 30
years at the Mayo Clinic.
Malcolm Bridwell, ’64 M.D., lives in Hobart and is staff
physician for the Oklahoma Department of Veterans Affairs - Clinton Center.
Robert V. Tate, ’64 M.D., lives in Bellingham, Wash. He
has retired after 31 years of general practice in Hemet, Calif.
Shelba Bethel, ’65 M.D., has practiced obstetrics and
gynecology in Norman for the past 40 years. For the last
14 years, her daughter, Lesa Bethel Mulligan, ’91 M.D., has
practiced with her.
Ildiko M. Sandford, ’65 M.D., practiced pathology for 34
years at the VA Northern California Health Care System.
She lives in Kensington, Calif., and provides laboratory
consulting for the State Commissioner for the College of
American Pathologists.
70s
Jack Beller, ’70 M.D., lives in Norman and, since 2006, has practiced orthopedic surgery in Chickasha. He is a member of the
Council on Legislation with the American Medical Association.
Lynn Harrison Jr., ’70 M.D., clinical director of cardiac
surgery at Baptist Health South Florida, has been named
chief of the division of cardiothoracic surgery and professor of clinical cardiovascular at Florida International
University’s new College of Medicine in Miami.
George H. Thompson, ’70 M.D., is professor of orthopedic surgery and pediatrics and director of the division of
pediatric orthopedics at Rainbow Babies and Children’s
Hospital in Cleveland, Ohio. He also is the co-editor of the
Journal of Pediatric Orthopaedics.
Clint Baisden, ’75 M.D., is director of CT surgery research
and faculty support at the University of Texas Health Sciences Center in San Antonio.
Michael Brantley, ’75 M.D., lives in Centennial, Colo.. He
Wayne Day, ’75 M.D., is retired from his obstetrics and
gynecology practice in Lewiston, Idaho, and now lives
in Clarkston, Wash.
Denise Farleigh, ’75 M.D., is director of breast imaging
at Providence Imaging Center in Anchorage, Alaska.
She is a board member of the Alaska Run for Women.
Janet Rodgers, ’75 M.D., lives in Oklahoma City and
is a full-time medical consultant for the Oklahoma
Department of Rehabilitation Services-Division of Disability Determination. Her training is in emergency and
forensic medicine.
B. Paul Choate, ’79 M.D., lives in Colorado Springs. He
is assistant chief of pediatrics and pediatric education
coordinator at Evans Army Community Hospital.
Debra L. Morgan, ’79 M.D., practices anesthesiology
at Claremore Regional Hospital with two other OU
medical graduates – her brother-in-law, Bill Morgan,
’78 M.D., and Eric Engles, ’83 M.D.
80s
Steven M. Babin, ’80 M.D., has been with the Johns Hopkins University Applied Physics Laboratory since 1983.
Deborah Beeson, ’80 M.D., lives in Tulsa. She practices
emergency room medicine for the Veterans Health Administration and is an active volunteer at local clinics.
J. Michael Lee, ’80 M.D., lives in La Quinta, Calif., where
he is chief physician and surgeon at Ironwood State Prison.
James L. Baker, ’81 M.D., is medical director of VNA
Hospice Care of Boston, having completed a fellowship
in palliative care in 2006 at Harvard Medical School,
Dana-Farber Cancer Institute and Massachusetts General Hospital. He has taught at Harvard Medical School
and Johns Hopkins School of Medicine.
Class Notes continued on page 52
[ FALL 2010 ]
PG. 51
CLASS NOTES
Class Notes continued from page 51
Mary LeBlanc Blumberg, ’84 M.D., lives in Virginia
Beach, Va., and practices surgical pathology with a
group in Norfolk.
John Evans, ’94 M.D., lives in Fort Worth, Texas, and
practices diagnostic radiology at Radiology Associates of
Tarrant County.
Edward Callaway, ’84 M.D., retired from the U.S. Air
Force in Germany and moved to Zurich, Switzerland, to
work for NightHawk Radiology.
Kelly Neaves McDonough, ’94 M.D., is co-owner of Breast
Imaging of Oklahoma in Edmond.
John Brookey, ’85 M.D., practices pediatrics in Pasadena, Calif., where he also is assistant medical director for
quality and risk management for Kaiser Permanente’s
Southern California regional offices.
Bob Nowlin, ’85 M.D., lives in Sallisaw, where he has an
internal medicine practice. He also owns and operates a
cattle ranch.
Robert B. Wilson II, ’95 M.D., practices pain medicine in
Salisbury, N.C.
Daniel R. Stough, ’64 M.D., Oklahoma City
Loren A. Dunton, ’45 M.D., Deland, Fla.
Stanley F. Brunn, ’65 M.D., Slate Hill, N.Y.
Daniel Friedman, ’47 M.D., Lady’s Island, S.C.
Theresa Stacy Williams, ’65 M.D., Guthrie
R. M. Kersten, ’49 M.D., Eugene, Ore.
Garland Leon Parks, ’67 M.D., Longview, Texas
Bill J. Reynolds, ’49 M.D., Norman
Erma Jean Mauch Rickey, ’67 M.D., Russellville, Ark.
M. C. Fuquay, ’52 M.D., Richmond, Va.
Preston A. Bagley, ’68 M.D., Newport Beach, Calif.
J. L. McGovern, ’52 M.D., Wellington, Kan.
Malcolm Robinson, ’68 M.D., Sarasota, Fla.
Robert E. Power, ’53 M.D., Santa Rosa, Calif.
Harold Harvey Haston, ’71 M.D., Peoria, Ill.
Henry L. Wall, ’53 M.D., Artesia, N.M.
Robert John Coffey, ’74 M.D., Tulsa
Troy O. Morgan, Jr., ’56 M.D., Mount Vernon, Mo.
Marshall Francis Stiles III, ’74 M.D., Denver
Marshall Hubbard Ingram, ’58 M.D., Hinton
Bruce W. Rumbaugh, ’76 M.D., Atoka
Helen I.T. Oglesby, ’59 M.D., San Francisco
Jeffrey S. Wheeler, ’76 M.D., Huron, S.D.
Thomas G. Goodwin, ’60 M.D., Hobart, Ind.
Ruth Margaret Carr, ’77 M.D., Los Angeles
Ronald Ray Sanders, ’60 M.D., Stillwater
James Mark Murphy, ’80 M.D., Oklahoma City
Sean A. Cupp, ’00 M.D., lives in Lawrence, Kan., and is
team physician for the University of Kansas Athletics and
Baker University Athletics.
Gerald Beckloff, ’61 M.D., Palm Desert, Calif.
Dwight M. McGlohon, ’81 M.D., Oklahoma City
John Alan Cone, ’64 M.D., Lewisville, Texas
Bradley George Haskell, ’00 M.D., Oklahoma City
Jarrett D. Kruska, ’00 M.D., practices urology in Enid and
is president of the Garfield County Medical Society.
J. Andrew Mulholland, ’64 M.D., Tulsa
Carol Padilla, ’85 M.D., lives in Topeka, Kan., and practices psychiatry at the VA medical center, working with
post-traumatic stress disorder outpatients.
00s
90s
Craig L. Abbott, ’90 M.D., has practiced dermatology
in Oklahoma City since 1994. He is chairman of the
board of visitors for Sam Noble Oklahoma Museum of
Natural History.
Susanti Chowdhury, ’90 M.D., lives in Largo, Fla. He
operates a pain management practice in Clearwater,
Largo and St. Petersburg and is active in the Florida
Academy of Pain Management.
Kathleen Seikel Goetz, ’90 M.D., is medical director of
pediatric emergency services at Swedish Medical Center
in Seattle, Wash. She lives in Graham.
Deaths
James Fitton Hohl, ’44 M.D., Bryan, Texas
N. Paul Ayers, ’99 M.D., practices interventional cardiology in Norman.
Robert (Bob) Overacre, ’85 M.D., is a private practice
anesthesiologist and current chief of the department
and medical director of the operating room at Baptist
Health in Little Rock, Ark.
Craig Cain, ’89 M.D., lives in Tucson, where she is a
partner in Southern Arizona Anesthesiology.
Matthew Paden, ’01 M.D., leads a team that received a
$1 million challenge grant from the National Institutes
of Health to refine a prototype kidney replacement device capable of treating children. He is assistant professor
of pediatrics – critical care at Emory University School
of Medicine and is the grant’s principal investigator.
W. Chris Sutterfield, ’95 M.D., is a partner with Surgical
Associates Inc. in Tulsa.
Lori Chaffin Jordan, ’99 M.D., is assistant professor of
neurology and pediatrics at Johns Hopkins University
School of Medicine and is associate director of the pediatric
neurology residency program. She recently received a
Ph.D. degree in clinical investigation from the Johns Hopkins School of Public Health.
Linda B. Andrews, ’89 M.D., is senior associate dean for
Graduate Medical Education (GME) at Baylor College of
Medicine in Houston.
Diane Hoa Tran, ’00 M.D., has practiced anesthesiology in Portland, Ore., since 2004. Since finishing her
residency, she has completed the Chicago, Marine Corps
and Portland marathons.
Amy Barton, ’00 M.D., is assistant professor of pediatrics
at University of Texas - Southwestern Medical School in
Dallas and is board secretary for the National Center for
Missing and Exploited Children. She resides in Colleyville.
Todd S. Barlow, ’00 M.D., is chief of surgery at Northwest
Medical Center in Bentonville, Ark.
Melinda J. (Mindy) Cail, ’00 M.D., practices family medicine in Edmond and has a weekly call-in radio show.
Chris Cassetty, ’00 M.D., completed his dermatology
residency at New York University as chief resident. He has
opened a solo practice, Hunterdon Dermatology, in Flemington, N.J. He and his family reside in Clinton, N.J.
[ FALL 2010 ]
PG. 53
ALUMNI
2011 Evening of Excellence to Honor
Zarrow, Crosby,
Inasmuch Foundation
The 27th annual Evening of Excellence, set for Jan. 27, 2011, will honor Tulsa businessman and
philanthropist Henry Zarrow; Warren Crosby, M.D., a national leader in protecting the health
of pregnant woman and infants; and the Inasmuch Foundation, dedicated to the betterment of
people, communities and the neighborhoods in which we live.
The gala is sponsored by the OU College of Medicine Alumni Association, with proceeds used
to provide seed grants to outstanding junior investigators and to senior scientists who are
opening a promising new area of discovery.
A record-setting crowd is expected for the event, which will be held at the National Cowboy
and Western Heritage Center.
Henry Zarrow
Warren Crosby, M.D.
Henry Zarrow
The Dean’s Award for Distinguished Community
Service will be presented to Henry Zarrow. A lifelong
Tulsan, Zarrow has led a remarkable life that has always
included a deep commitment to giving to those in need
and ensuring access to social and medical services.
Zarrow was the first son of Sam and Rose Zarrow,
who immigrated to the United States from Russia. He
went to work in the family grocery business at age 6
Edith Kinney Gaylord
and opened his own grocery store at age 13, working before
and after school. At age 22, he started Sooner Pipe and Iron,
which later became Sooner Pipe and Supply, the largest independent pipe and supply business of its kind in the world.
He began making charitable donations even before he had
fully paid for his first truck for the business. He sold the
business in 1998.
The Zarrow family and the Anne and Henry Zarrow
Foundation have been exceptionally generous donors to
programs and projects on OU’s campuses in Norman, at
the OU Health Sciences Center in Oklahoma City and at
OU-Tulsa. Their philanthropy has benefited a range of important areas from scholarships (including nursing scholarships) to faculty endowments, from the Harold Hamm
Oklahoma Diabetes Center to the Sam Noble Oklahoma
Museum of Natural History and from campus beautification to the OU Wayman Tisdale Specialty Health Clinic in
north Tulsa
In 2008, the first Henry Zarrow Presidential Professorships were awarded to H. Anne Pereira, Ph.D., associate
professor of pathology in the College of Medicine, and
Tyrell Conway, professor of botany and microbiology in
the College of Arts and Sciences.
In 2009, shortly after Henry Zarrow celebrated his 93rd
birthday, the OU School of Social Work received a present from his family – a $5 million gift from the Anne and
Henry Zarrow Foundation to help build a new home for
social work. His children, Judy Kishner and Stuart Zarrow,
and grandchildren, Julie Cohen, Dr. Jay Wohlgemuth and
Dr. Edward Zarrow, all of whom are trustees of the Anne
and Henry Zarrow Foundation, agreed that a major gift to
the School of Social Work would be an exceptionally fitting
way to honor Zarrow and his late wife, Anne, his partner
in life and in giving for 65 years. The school and its new
home – currently under construction – have been named
for Anne and Henry Zarrow.
Additionally, the Anne and Henry Zarrow Foundation
has made gifts to many other programs throughout the
state, with a special interest in children’s issues, the homeless and the poor. Together, Anne and Henry Zarrow
dreamed of a Tulsa Center for the Homeless and worked
and gave the funds to make it a reality. They have played
leading roles in helping the public schools, in developing
a senior citizens center in Tulsa, in building libraries in
the Tulsa area, and in establishing a center to help those
with mental health needs. During his life, Henry Zarrow
has chaired or led the boards of more than 50 charitable
organizations in Oklahoma.
Warren M. Crosby, M.D.
The Dean’s Award for Distinguished Medical Service
will be awarded to Warren M. Crosby, M.D., retired vice
chair of the Department of Obstetrics and Gynecology, who dedicated his career to ensuring that expectant
mothers and their infants throughout rural areas of state
receive excellent medical care. The systems, procedures and programs he initiated in the 1980s to reduce
the rate of infant mortality in Oklahoma continue to
save lives today.
For example, it was through Crosby’s efforts that
Oklahoma hospitals offering delivery services began
banking blood and having it available during childbirth.
Hemorrhage ceased to be the leading cause of death
during childbirth in the state.
The Office of Perinatal Continuing Education,
housed in the College of Medicine, was founded and
directed by Crosby to offer training in the best perinatal
practices for physicians, nurses and other personnel in
rural hospitals offering delivery services.
Crosby established a statewide system to ensure that
uninsured and indigent women with high-risk pregnancies be directed to University Hospital for delivery
of their babies.
An information-sharing system was developed by
Crosby between University Hospital, where many indigent women “dropped in” to have their babies, and the
local charity clinics where these expectant mothers had
been seen. The system gave hospital personnel muchneeded health information about these patients before
they arrived to deliver.
At the national level, it was Crosby’s seminal research in the early 1970s into seatbelt safety for pregnant
women that led to the development and recommended
appropriate use of seatbelts that pregnant women nationwide follow today to protect themselves and their
unborn children.
The Topeka, Kan., native attended Stanford University and received a bachelor’s degree in 1953 from
Washburn University, Topeka, before graduating from
the University of Kansas School of Medicine in 1957.
Crosby interned at St. Luke’s Hospital in Kansas City
before completing residency training in obstetrics and
gynecology at University of California Hospitals, San
Francisco, where he was chief resident.
Crosby joined the OU College of Medicine faculty in
1962 and was vice chair of the Department of Obstetrics
and Gynecology from 1969 to 1994. He remains a clinical professor in the department.
His commitment to the health of women and their
infants is reflected in his service as vice chair of the Oklahoma Committee for Perinatal Health, consultant to
the Oklahoma Improved Pregnancy Outcomes project,
Evening of Excellence continued on page 56
[ FALL 2010 ]
PG. 55
ALUMNI
Evening of Excellence continued from page 55
director of the Oklahoma Rural Infant Care project,
medical adviser to Oklahoma Health Futures and member of the Governor’s Task Force on Perinatal Care.
Inasmuch Foundation
The Dean’s Award in Recognition of a Distinguished Oklahoma Institution will be awarded to the
Inasmuch Foundation.
Edith Kinney Gaylord’s longtime commitment to
education, arts, health and human services, historic
preservation and the environment was formalized with
the creation of the Inasmuch Foundation in 1982. The
name comes from the New Testament passage in Matthew: “Inasmuch as you have done it unto one of the
least of these, my brethren, you have done it unto me.”
Since inception, the Inasmuch Foundation’s gifts of
more than $6 million to the OU Health Sciences Center
represent investment in two research facilities and four endowed chairs, the start-up support for multiple programs
and dissemination of research results.
Gaylord also founded the Ethics and Excellence in Journalism Foundation, reflecting a lifelong devotion to journalistic
excellence. The daughter of Inez and E.K. Gaylord, she grew
up in the newspaper business. In 1943, she joined the Associated Press in Washington, D.C., where she was the only
woman on the general news staff and covered Eleanor Roosevelt’s news conferences, was secretary of Mrs. Roosevelt’s
press conference committee and acted as liaison between the
First Lady and members of the press. In 1944, she was elected
president of the National Women’s Press Club.
She returned to Oklahoma City in 1963 to rejoin the
2011 Alumni Day and
Remembering old times are Marilyn and Martin Hullender, ’65 M.D., Altus, and Sherry and Gary Strebel, ’65 M.D., Oklahoma City.
All attended the 2010 Reunion Banquet sponsored by the OU College of Medicine Alumni Association in May. Next year’s Alumni Day
and Reunion events will be May 6.
family business and began supporting numerous community organizations and projects.
Together, Inasmuch and the Ethics and Excellence in
Journalism Foundation have collectively awarded over
$120 million to nonprofits nationwide.
Inasmuch Foundation’s support on the OU Health
Sciences Center campus includes $2.5 million to the Dean
McGee Eye Institute for a new clinical/research building
housing the Department of Ophthalmology and $2 million to the OU Cancer Institute. The gift to OUCI includes
startup grants of $760,000 for the Family Services Program
and $240,000 for the Oklahoma Cancer Outreach Program,
and $1 million for an endowed faculty chair in cancer
screening, outreach and education.
A $500,000 grant to Children’s Medical Research Institute, now the Children’s Hospital Foundation, established
an endowed faculty chair in the College of Medicine
for the Pediatric Type 2 Diabetes Research Program.
Another $500,000 grant to CMRI established the final
$2 million faculty chair in the Jimmy Everest Center for
Cancer and Blood Disorders in Children.
Inasmuch Foundation also enabled creation of the
Interdisciplinary Training Program in Child Abuse and
Neglect in the OU Child Study Center in the Department of Pediatrics, and it also has supported efforts by
the College of Public Health to protect young people
from risk-taking behaviors.
Reservations for the event may be made by contacting alumni association director Carol Modisette, at
(405) 271-2300 or [email protected].
Reunion Set May 6
Enjoying themselves at the reception preceding the 2010 Reunion Banquet at the Oklahoma History Center are, from left, Ray
von Schlageter and Margo Shultes, ’00 M.D., Edmond; and Erin Richey Frazier, ’00 M.D., and James Frazier, Louisville, Ky.
[ FALL 2010 ]
PG. 57
ALUMNI
PHILANTHROPY
Two New Fundraisers Named for Medicine
Two veteran OU development professionals, Stacey Barry and John Cougher, have
been appointed to new fundraising positions
for the OU College of Medicine.
“Stacey and John are two of the most
successful fundraisers in our Development
organization,” said Vice President Tripp
Hall. “Both are experienced, hard-working
and dedicated to the mission of our university. I am confident they will serve the
College of Medicine and its students well.” Barry, executive director of development,
has been executive director of the highly successful President’s Associates Program since
2007. In that position, she worked closely with
hundreds of alumni and friends to raise significant private funds in support of virtually
every academic area at OU. Prior to joining
the Associates staff in 2006, she was in OU’s
Administrative Affairs division.
A native of Sand Springs, Barry earned
her bachelor’s degree in secondary education with a minor in English in 1992 from
OU, where she was a member of the President’s Leadership Class. She was a language
arts teacher in the Norman Public School
Stacey Barry
John Cougher
System for seven years and in management with the Hal Smith Restaurant
Group for five years. Barry has two children, John and Katie.
Cougher is the new director of development for the college. Most recently, he was
director of development for the Jeannine
Rainbolt College of Education, a position
he had held since March 2008.
Before joining OU, Cougher worked
for various nonprofits in development,
financial, and leadership roles, including serving as development director
for HeartLine, a nonprofit providing
central Oklahomans with information
and social services.
A native of Lawrence, Kan., Cougher
graduated from the University of Kansas,
earning a bachelor’s degree in Germanic
languages in 1997. He also spent two years
studying languages at the University of
Bonn in Germany and is currently enrolled
in OU’s public administration master’s
degree program.
Cougher has two children, Sadie, 3, and
Oliver, 1.
Thank You
for your generosity to the
University of Oklahoma College of Medicine.
The College of Medicine gratefully acknowledges our
alumni and friends who gave so generously between
July 1, 2009 and June 30, 2010, and we are pleased to
list them on the following pages.
Gifts large and small received during the period totaled
$33,224,656.13, each gift demonstrating your commitment
to our mission of providing excellence in education,
research and patient care.
Every effort was made to ensure accuracy in this report. However, should you notice errors,
please report them to the Office of Alumni and Development, OU Health Sciences Center,
1000 Stanton L. Young Blvd., Ste. 162, Oklahoma City, OK 73117-1208.
First-Year Students Receive Stethoscopes
Alumni and development staff hand out stethoscopes to every first-year student at the annual “end of first-week picnic” sponsored by the OU
College of Medicine Alumni Association. The stethoscopes are purchased with special gifts from association members.
[ FALL 2010 ]
PG. 59
$8 Million and Above
$4 Million to $7.9 Million
Oklahoma Grand Chapter
Rein In Cancer
State of Oklahoma
The Williams Foundation
Harold Hamm
George Kaiser Family Foundation
$10,000 to $24,999
Children's Hospital Foundation
$3 Million to $3.9 Million
Wilton W. Webster Jr.
$1 Million to $2.9 Million
Chickasaw Nation
The Samuel Roberts Noble Foundation Inc.
Lynn Schusterman
$750,000 to $999,999
Estate of Elma G Johnson
Charles & Lynn Schusterman Family
Foundation
$400,000 to $749,999
Anonymous Donor
Tulsa Community Foundation
$300,000 to $399,999
The Herman Kaiser Foundation
Donald W. Reynolds Foundation Inc.
St. John Medical Center
William K. Warren Foundation
$200,000 to $299,999
Estate of George S. Bozalis
Founders and Associates Inc.
Hille Family Charitable Foundation
Morningside Health Care Foundation
Tulsa Foundation for
Health Care Services Inc.
Anne & Henry Zarrow Foundation
$100,000 to $199,999
Britani T. Bowman
Health Care Service Corporation
The Helmerich Foundation
Presbyterian Health Foundation
Gene Rainbolt
$50,000 to $99,999
Herbert & Roseline Gussman Foundation
Nelson Hyde
George B. Kaiser
Merkel Family Foundation
NFG Foundation
Oklahoma Gas & Electric Foundation Inc.
W. K. Warren Jr.
The Wisdom Family Foundation Inc.
$25,000 to $49,999
Bank of America Foundation
James A. Crabtree, M.D.
Warren M. Crosby, M.D.
Pam Fleischaker
John E. Fitch
Ford Audio-Video Systems Inc.
Robert Gholston
Hardesty Family Foundation
Dr. Laurence Jones Trust
The Lynn Health Science Institute
Merrick Foundation
National Breast Cancer Foundation Inc.
Oklahoma Foundation for
Digestive Research
7-Eleven Stores
Ally's House Inc.
American Osteopathic Foundation
M. Dewayne Andrews, M.D.
Lloyd G. Austin
John R. Barker
Estate of Travis Dewey Barnett
The Mervin Bovaird Foundation
Emergent Technologies Inc.
Jane C. Fitch, M.D.
William A. Geffen, M.D.
James N. George, M.D.
Laura M. Good
GPK Foundation
Heritage Hall
Walter S. Snodell
Carl Swanson
Tulsa Teachers Credit Union
Michael S. Turner
Anonymous Donor
Elizabeth G. Wall
$5,000 to $9,999
Aflac
American Medical Systems Inc.
AT&T Oklahoma
Pat Blevins
Carl R. Bogardus Jr., M.D.
Christopher M. Boxell, M.D.
Broken Arrow Lady Elks
Robert M. Byers, M.D.
Judy Carter
Roger Cole
Jonathan E. Drummond, M.D.
Fleischaker Family Foundation
Josephine W. Freede
Patricia Peter Gambulos Family Trust
Grand Aerie, Fraternal Order of Eagles
Harris Foundation Inc.
Health Dash
Bretton H. Jameson, M.D.
Greg A. Krempl, M.D.
Walter L. Lamar, M.D.
Modern Wealth Management Inc.
Oklahoma City Community
Foundation Inc.
Oneok Foundation Inc.
OU Cancer Institute
OU Medical Center
Ann D. Paul
Paul-Drennan Family
Charitable Foundation
Physicians Liability Insurance Co.
George J. Records
Sanford C. Bernstein & Co., LLC
Bryan E. Scheer, M.D.
Rose Sharp
Kimberly S. Smith, M.D.
William T. Turner, M.D.
Whistlestop Ranch
Young Living Essential Oils
$1,000 to $4,999
Adams Charitable Foundation
Agar-Ford-Jarmon & Muldrow
Roxie Albrecht, M.D.
Thomas C. Alexander, M.D.
Von E. Allen
Richard J. Allgood, M.D.
Ann S. Alspaugh
American Fidelity Foundation
American Quarter Horse Foundation
Robert E. Anderson, M.D., Ph.D.
Anonymous Donor
Anonymous Donor
A. M. Arky, M.D.
Sinclair W. Armstrong Jr., M.D.
Autism Research Institute
Zaheer U. Baber, M.D.
Dennis D. Baggett
BancFirst
Bank of Oklahoma - OKC
Bank of Oklahoma NA
Todd S. Barlow, M.D.
Duane A. Barnett, M.D.
J. M. Bazih, M.D.
Jack J. Beller, M.D.
Bernhardt Oil Corp.
William G. Bernhardt, M.D.
Peter D. Binstock, M.D.
Biotronik Inc.
Elizabeth W. Blankenship
Kenneth E. Blick, Ph.D.
Robert W. Block, M.D.
Harvey J. Blumenthal, M.D.
Elaine P. Boatsman
David W. Bobb, M.D.
Betty Borelli
Terrence H. Boring, M.D.
John R. Bozalis, M.D.
Bricktown Rotary Foundation
Jerry D. Brindley Jr., M.D.
Michael S. Bronze, M.D.
Ronnie D. Brownsworth, M.D.
Mary C. Bruce
Byng Public School
Jay P. Cannon, M.D.
Cardionet Inc.
J. Christopher Carey, M.D.
Bradley D. Carter, M.D.
Donald R. Carter, M.D.
John N. Carter, M.D.
Sandra K. Cesario, Ph.D.
Larry K. Chase, M.D.
Chesapeake Operating Inc.
Gerard Clancy, M.D.
Robert M. Clark, M.D.
Lisa K. Clayton, M.D.
Marna Clippinger
Heath Coleman
College of Nursing Student Association
Kenneth H. Cooper, M.D.
James R. Couch Jr., M.D.
Harriet W. Coussons, M.D.
R. Timothy Coussons, M.D.
Christopher G. Covington, M.D.
Benjamin D. Cowley Jr., M.D.
Crowe & Dunlevy
S. Edward Dakil II, M.D.
Steven G. Danley
Deaconess Healthcare Corp.
Dean A. McGee Eye Institute
The Honorable Lee Denney
Devon Energy Corporation
William E. Dickey Jr.
Dillard Charitable Trust
William C. Dooley, M.D.
F. Daniel Duffy, M.D.
Kay F. Duffy
Sherri S. Durica, M.D.
Dr. John W. Dyer
James R. Earley, M.D.
Susan M. Edwards, M.D.
Barry R. Eisen, M.D.
Ronald C. Elkins, M.D.
Charles C. Elliott, M.D.
Edwin F. Ellis, M.D.
Energy Financial Solutions LLC
Phyllis P. Engles, M.D.
Robert E. Engles, M.D.
Marilyn Escobedo, M.D.
Dr. Frank J. Evans
Christy Everest
James H. Everest
Evergreen Foundation
Excell Home Care and Hospice Inc.
Stephen A. Feuerborn, M.D.
First Capital Bank
John I. Fishburne Jr., M.D.
John M. Flack, M.D., M.P.H.
David A. Flesher, M.D.
David J. Flesher, M.D.
Flintco Inc.
C. Douglas Folger, M.D.
Charles J. Foulks, M.D.
Foundation for Anesthesia Education
& Research
Stephanie L. Franklin
G. Rainey Williams
Surgical Symposium
Dee Gammill
John H. Gardner, M.D.
Michael O. Gardner, M.D.
Donald H. Garrett, M.D.
Elizabeth A. Jett, M.D.
Keith E. Gawith, M.D.
Gelvin Foundation
Genzyme Corporation
James R. Geyer, M.D.
Mark H. Gillie, M.D.
Ronald L. Gillum, M.D.
Thomas R. Godkins
R. Nathan Grantham, M.D.
Charles S. Graybill, M.D.
Greater OKC Chamber of Commerce
Peter Gries
John D. Groendyke
Michael J. Hahl, M.D.
Nancy K. Hall, Ph.D.
Donald B. Halverstadt, M.D.
Joe B. Harbison, M.D.
Betty M. Harding
Thomas D. Harris, M.D.
Lynn H. Harrison Jr. M.D.
Joseph Harroz, M.D.
Kim R. Hauger, M.D.
Michael H. Hennessey, M.D.
Glen A. Henry, M.D.
Jeffrey G. Hirsch, M.D.
The Hobbes Foundation
Sarah C. Hogan
John H. Holliman, M.D.
Harry C. Holloway Jr., M.D.
Gayle Holmes
Sonya Holmquist, M.D.
Brooke L. Honey
Carl T. Hook, M.D.
Courtney W. Houchen, M.D.
Douglas H. Huber, M. D.
Laurie M. Hyde
Mercy M. Hylton, M.D.
John J. Iandolo, Ph.D.
Norman K. Imes Jr., M.D.
In His Image International Inc.
Rhett L. Jackson, M.D.
Richard H. Jackson, M.D.
Robert N. Jarman, M.D.
David H. Jelley, M.D.
Barbara E. Jett
Kirk Johnson
Robert G. Johnson, M.D.
Kristy L. Jones, M.D.
Oliver W. Jones Jr., M.D.
George Kammerlocher
Don Karns, M.D.
Donald J Kastens, M.D.
David C. Kem, M.D.
John M. Kennedy Jr.
William F. Kern III, M.D.
Branson R. Kester, M.D.
Knapheide Manufacturing Co.
Scott Knappenberger, M.D.
Sammy H. Kouri, M.D.
Luiz P. Kowalski, M.D.
Kennon L. Kuykendall, M.D.
LaGrange Leather
M. Stanley Lee
Sarah T. Lepak
The Timothy D. Letter
Memorial Foundation
Robert J. Livingston, DDS Inc.
Shirley L. Livingston
Robert J. Lockwood, M.D.
John S. Long Jr., M.D.
Lost Creek United Methodist Church
Tom E. Love
Craig H. Lubin, M.D.
Jeffrey D. Lynch
Timothy J. Lyons, M.D.
Macklanburg-Hulsey Foundation
Brian Maddy
W. E. Maldonado, M.D.
Virginia A. Manchester
Thomas A. Marberry, M.D.
Marvin K. Margo, M.D.
Robert W. Maxwell, M.D.
Gerry Mayes
McAfee & Taft PC
McAlester Regional Health Center
Andrea C. McCartney
Stacy C. McDaniel
Tom J. McDaniel
John A. McIntyre, M.D.
Emily McLaurin
Erin McLemore, M.D.
D. Anthony Melman
Nancy Mercer
Frank Merrick
Miles Associates Incorporated
Douglas C. Miller, M.D.
Floyd F. Miller, M.D.
J. Steve Miller, M.D.
Kevin W. Miller, M.D.
Mark R. Miller, M.D.
Mojtaba Moghadam, M.D.
J. Charles Monnet, M.D.
Nancy W. Moore
Robert J. Morgan, M.D.
Morningstar Emergency Physicians PLLC
Misti D. Mosley
Mark R. Mueller, M.D.
Regina Murphy
Michael Murray, M.D.
Mustang Fuel Corporation
R. Z. Naifeh
Sumit K. Nanda, M.D.
Bruce A. Naylor, M.D.
Victor R. Neal, M.D.
John B. Nettles, M.D.
Robert C. Newman, M.D.
Nadim F. Nimeh, M.D.
Nancy E. O'Dell, M.D.
Martha K. Ogilvie, Ph.D.
OK State Aerie
Oklahoma Allergy & Asthma Clinic
Oklahoma Cardiovascular Association
Oklahoma City Clinic
Oklahoma Publishing Company
Oklahoma State Medical Association
Robert L. Overacre, M.D.
Margaret Freede Owens
Lynne V. Ozinga, M.D.
Nicholas J. Pappas, M.D.
David T. Parker
K. Michael Parker, Ph.D.
Christopher A. Paskowski, M.D.
David Paslay
Pawhuska Public Schools
Larry R. Pennington, M.D.
Betty J. Pfefferbaum, M.D., J.D.
Pinto Heritage Foundation Inc.
Frances M. Power
Ford Price III
Victor W. Pryor Jr.
Lorenz T. Ramseyer, M.D.
J. Randall Rauh, M.D.
Dr. Nancy E. Ray
Ghazi M. Rayan, M.D.
A. J. Reed, M.D.
J. R. Reichert
William G. Reiner, M.D.
Mark A. Riner, M.D.
Robert E. Ringrose, M.D.
Don A. Rockwell, M.D.
Mary L. Ross
Lawrence I. Rothblum, Ph.D.
Spencer I. Rozin, M.D.
Richard A Ruffin, M.D.
Jeannie Sacra
Janice B. Sandri
John H. Saxon III, M.D.
Frank Schmidt, M.D.
James H. Schmidt, M.D.
Lee E. Schoeffler, M.D.
Thomas P. Schroedter
John F. Schuhmacher, M.D.
Norman J. Schultz, M.D.
Alissa Schumacher
Mahendra S. Shah, M.D.
Donald J. Sheffel, M.D.
Lonnie P. Shell
Shoreline Capital Ltd.
Robert D. Shuttee, M.D.
Jeannette F. Sias
R. L. Sias
Shelly L. Singleton
Patsy L. Sloat
Smith & Pickel Construction Inc.
Kristen R. Smith
Lisa A. Smith
Lisa Smith
R. Brent Smith, M.D.
Sarah M. Smith, M.D.
David J. Sokatch
Southwest Center for Dentistry
Splash for CF
Kristen V. Squires
Nabil E. Srouji, M.D.
David O. Staats
H. Keith Stonecipher, M.D.
L. Clarke Stout Jr., M.D.
Michael L. Stratton, M.D.
Gary F. Strebel, M.D.
Daron G. Street, M.D.
Stephen L. Styron, M.D.
Eleatha L. Surratt, M.D.
Laurie S. Swaim, M.D.
Charles M. Swaney, M.D.
Rebecca J. Swaney, M.D.
Sylvan N. Goldman Center
Michael L. Talbert, M.D.
John W. Tipton, M.D.
J. Harold Tisdal, M.D.
Christine E. Tormey
Valliance Bank
Marilyn W. Vandever
Jerry B. Vannatta, M.D.
Connie Vansickle
Charles A. Vose Jr.
Douglas W. Voth, M.D.
Thienkhai H. Vu, M.D., Ph.D.
Joseph L. Waner, Ph.D.
Douglas Warner III
Watonga Christian Church
F. E. Webb Jr., M.D.
James G. Webb, M.D.
Ted E. Webb, M.D.
Diana M. Webber
Randal S. Weber, M.D.
Robert J. Weedn, M.D.
Paul H. Weigel, Ph.D.
William G. Weppner
Michael H. Whalen, M.D.
Robert G. White, M.D.
Thomas L. Whitsett, M.D.
Kenneth W. Whittington, M.D.
Martha V. Williams Revocable Trust
Valerie N. Williams, Ph.D.
Randall J. Willis, M.D.
Robert B. Wilson II, M.D.
Arthur F. Windholz, M.D.
Michael L. Winzenread, M.D.
Ervin S. Yen, M.D.
Laura M. Young, M.D.
John J. Zavoshy, M.D.
John P. Zubialde,M.D.
Gifts to $999
Mary Acree
Frances L. Adams
Adriaan Hair Design Inc.
Leeland N. Alexander
Gordon E. Alldrin, M.D.
Tate B. Allen, M.D.
Kimberly A. Allen
Otella Allen
Scott Allen
E. W. Allensworth, M.D.
Heather J. Allphin
Whitney R. Alvis
American Academy of Pediatrics
American College of Physicians
American Morgan Horse Association
Brent Anderson
Carl B. Anderson III
Dean N Anderson
Elaine Anderson
Ron J. Anderson, M.D.
Sarah J. Anderson
Steven R. Anderson
Tracie S. Anderson
Anonymous Donor
Michael J. Anton
Robin Antonio
Sandra L. Arnett
C. W. Arrendell Jr., M.D.
Arvest Bank Operations, Inc.
Judith S. Asher, M.D.
John R. Ashley, M.D.
Gerald S. Asin, M.D.
Mary K. Audd
Paul D. Austin
AVL Systems Design
AWHONN Oklahoma Section
William A. Aylesworth
Samina Baber
Guy Bacon
David M. Bailey, M.D.
Jerry Baird
C. Paul Baker Jr.
James M. Baker, M.D.
M. Baker
R. S. Baker Jr.
David W. Bank, M.D.
Bank of America Foundation
Bank of Oklahoma
James T. Banta, M.D.
Sharon L. Barber, M.D.
Joan K. Barnes
Debra K. Barns, M.D.
Jon Barry
J. Edward Barth
Jennifer Bartley
Jo Bassett
Janet Bates
John L. Baumert
Janice L. Bazarian, M.D.
Gail Kendall Beals
The Beard Company
James H Bearden, M.D.
Christopher Bearss
Rachel Beasley
Sherry L. Beasley
Sheral Becerra
Charles E. Beck, M.D.
Karen J. Beckman, M.D.
James H. Beeson, M.D.
Heather Belanger
Tracey Bell
Hilary Belter
Melissa I. Bennett
Sherry Bennett
Sally F. Bentley
Sally Berger, M.D.
Gloria L. Beriones
Dr. Judy O. Berry
Charles F. Bethea, M.D.
Rev. Lander L. Bethel Jr.
Cathryn Bias
Paul C. Bierig, M.D.
Big 12 Conference
In bold-face type are names of OU President’s Associates who designate the College of Medicine as beneficiary of their annual membership gifts.
[ FALL 2010 ]
PG. 61
Big Red Sports/Imports
Biosite
Philip C. Bird, M.D.
Dr. David J. Birdwell
David W. Bishop, M.D.
Bishop McGuinness High School
Janice M. Bisson
Jennifer Blackburn
William C. Blackledge, M.D.
Carol Ann Blackwood
Greg L. Blair
Deborah S. Blalock, M.D.
James M. Blalock, M.D.
Diane M. Blanchard
Hilarie H. Blaney
G. T. Blankenship
Pollie Blanton
Susan Blinten
Bruce L. Bockus
Michelle A. Boice, M.D.
Frank M. Bolen
Barbara L. Bonner, Ph.D.
Molly S. Boren
Adam Borowski, M.D.
Sylvia S. Bottomley, M.D.
Andrea Boutwell
Robert P. Bowles
Charles B. Bowman, M.D.
Bobby L. Boyanton, M.D.
Deborah S. Boyer, M.D.
David Bozalis
Donna W. Bozalis
Cheryl K. Bradford
Reagan H. Bradford Jr., M.D.
Rita M. Bradley
Martha F. Bradshaw
Lance M. Bradt
M. Edmund Braly, D.D.S.
Michael J. Brantley, M.D.
Steven P. Brantley, M.D.
Mrs. Phyllis T. Brawley
Travis Brawner, M.D.
Vincent M. Brigham
John M. Brookey, M.D.
J. T. Brooks, M.D.
Mrs. Paul C. Brou
Deborah D. Broughan
Vivian F. Brower
Brandon Brown
David R. Brown, M.D.
Janet M. Brown
Nancy H. Brown
Robert C. Brown, M.D.
Terry N. Brown, M.D.
Robert H. Broyles, Ph.D.
Tracie Bruce
Stephanie Bruinooge
Dixie Bryant
Richard J. Bryce
Rebecca A. Buchanan
Barbara L. Burdick
Virginia D. Burdine, M.D.
William C. Burnett, M.D.
Mark C. Burr, M.D.
Otis F. Burris, M.D.
Duane A. Burroughs, M.D.
Frank R. Burton, M.D.
Mary S. Burton, M.D.
Arthur W. Buswell, Col., M.D.
Harrison G. Butler III, M.D.
Benjamin J. Butts
Cosme R. Cagas, M.D.
Gail G. Cahill
Joan P. Cain, M.D.
Christine Caines
Tim S. Caldwell, M.D.
Hilary P. Califano
CAM Energy LLC
Mrs. C. B. Cameron
Gregory R. Campbell, M.D.
Nancy E. Campbell
Stephen B. Campbell, M.D.
Christopher S. Candler, M.D.
Vikki A. Canfield, M.D.
J. Donald Capra, M.D.
Carbondale Assembly of God
Sam D. Carnahan
Amy Carothers
Carr & Carr
Terry Carris
Miles Carslisle
Ruth Carson
Beverly A. Carter
Maureen C. Carter
Merle D. Carter, M.D.
R. T. Carter
Robert G. Case, M.D.
Virginia F. Casey, M.D.
Alvah R. Cass, M.D.
Kathaleen Cassidy
Ester Cater, M.D.
Michael A. Cawley
Cynthia E. Cessant
Shouvik Chakrabarty, M.D.
Susan L. Chambers, M.D.
Joanna M. Champlin Revocable Trust
Joanna M Champlin
Kitty J. Champlin
Judith F. Chant
John P. Cheatham, M.D.
Cheek & Falcone, PLLC
Christopher Y. Chow
Marion D. Christensen, M.D.
Julia Christman
Steven Chrysant, M.D.
Warren C. Churchill
City of Fairbanks FCU
Kerry R. Clark, M.D.
Roger C. Clark
Rose Clark
Donald Clem
Ted Clemens Jr., M.D.
John P. Clemons, M.D.
Michael L. Clifton Jr.
Kelsey J. Cline
Frank A. Clingan Society
Barbara E. Cluck
Tiajuana K. Cochnauer
Paul C. Cochran, M.D.
Dennis W. Coffman, M.D.
Mr. John Cohlmia
James G. Coldwell, M.D.
B. Ann Cole
Steven P. Cole
Tammy Cole
David M. Collins
Debra C. Collins
Peggy G. Collins
Stephanie K. Collison Rev. Trust
Ms. Mary J. Colomb
Communities Foundation of
Oklahoma Inc.
David J. Confer, M.D.
Stephen D. Confer, M.D.
ConocoPhillips Co.
Jason E. Constable
Cynthia E. Cook
Debra C. Cook
Robert L. Cooksey
Tina Marie Cooper, M.D.
Norvell V. Coots, M.D.
Kenneth C. Copeland, M.D.
Helen L. Corcoran, M.D.
Mark S. Cotner, M.D.
Couch Pharmacy
Anne C. Courtright, M.D.
Jereme Cowan
Patrick Cowan
Douglas G. Cox, M.D.
CPI Wirecloth & Screens Inc.
Richard B. Crabb, M.D.
Jane H. Crain
Russell D. Crain, M.D.
Michael A. Crews, M.D.
David A. Cross, M.D.
Lee R. Crouch
Crowe & Dunlevy Foundation Inc.
Thomas E. Crump
Douglas R. Cummings
Glenn R. Cunningham, M.D.
Cuppies & Joe LLC
Ray E. Curle, M.D.
Luke M. Curley
Curtis and Company PLC
Cushing High School
DeJean L. Dace, M.D.
Alice R. Dahlgren
Anita Dahlgren
Sami S. Dahr, M.D.
Kathy L. Daigle
Pam Dalton
Walter C. Dandridge Jr., M.D.
Patricia Dandrow
Julie Jacobs Daniels
David L. Dautenhahn, M.D.
Justine C. Dautenhahn, M.D.
Charles Davis
Karen L. Davis
Mark A. Dawkins, M.D.
DCP Midstream
Rita G. Dearmon
Wilbert H. Deering
Julian V. Deese, M.D.
Chris Degner Trust
E. Julia De Hart
Roy L. De Hart, M.D.
Amanda D. Delahay, M.D.
David M. Delahay, M.D.
Maxcine Denton
Jordan C. Deschamps-Braly, M.D.
J. Allen Dick Jr.
Stephen J. Dick, M.D.
Mrs. David R. Dickey
Tuan-A D. Diep, M.D.
Dr. Melissa Dietz
Justin D. Digby, M.D.
Peter Dillingham
Joseph Dina
Linda Dindzans
Carol T. Dixon
Jason M. Dixon
Jeff Dixon, M.D.
James D. Dixson, M.D.
Lisa Dobberteen, M.D.
Brenda L. Dobbs
Stephen T. Dobson
Andrew J. Dodge, M.D.
Phillip G. Doerner, M.D.
Kay T. Heimlich
DeNiece Donalson
Deborah Donnor
G. Kevin Donovan, M.D.
Lisa d'Orio
Thomas E. Douthit Jr., M.D.
Mr. Gordon Downey
William H. Downham, M.D.
John K. Doyle, M.D.
John P. Drake
S. A. D. Drooby, M.D.
Marlana A. Drumwright
Aimee D. Duboise
Jim G. Duckett, M.D.
Dulaney Bros. Investments
J. L. Dunagin Jr., M.D.
Barbara Dunai
Duncan Family Partnership
Robert C. Duncan
David E. Dunlap
Marianne E. Dunlap, M.D.
Vincent B. Dunlap
Betty M. Dunning
Mary Durbin
Clinton E. Duval, M.D.
James W. Dyer, M.D.
Kerry Ebersole
Linda L. Edmondson
Janet Edwards
Phil L. Edwards
Susan A. Edwards
Pete Eischen
Arthur F. Elliott
Irma B. Elliott
R. C. Elliott, M.D., PC
Nancy P. Ellis
Robert S. Ellis, M.D.
Michael Ellis
David L. Emanuel, M.D.
Ralph C. Emmott, M.D.
Heidi Engel
John C. England, M.D.
Mary England
Robert B. Epstein, M.D.
Joe Esco
Esinel Energy
Eurand Pharmaceuticals Inc.
J. Patrick Evans, M.D.
James M. Evans, M.D.
Bruce L. Evatt, M.D.
Dan A. Evatt
Janell G. Everest
William P. Fagala
Barbara H. Farber
Ranee M. Fear
Toby Fell
Warren L. Felton III, M.D.
Patricia G. Fenderson, M.D., Ph.D.
Nancy L. Fennell
Terry H. Fenner
Mark A. Fergeson, M.D.
Joseph J. Ferretti, Ph.D.
David Ficca
Bobbie D. Fine, M.D.
Paul M. Finer, M.D.
First National Bank
In bold-face type are names of OU President’s Associates who designate the College of Medicine as beneficiary of their annual membership gifts.
First Signs Inc.
Paul L. Firth, M.D.
Joy D. Fischer
Dr. Paul Fishkin
Mark K. Fitch
Jay L. Fitzgerald
SoRelle Fitzgerald
Mary E. FitzSimons
Heidi Flanga
Janis Flatt
Dolly Flesher
Flexible Marketing LLC
Donald R. Flinn
Robert W. Florence, M.D.
Kim D. Followwill
Beth Ford
Claire M. Ford
Laura L. Fortado
Donald L. Foster, M.D.
Rick Fowler
Margaret W. Fowles
Drs. E.M. Fox & J.E. Fields LLP
G. Douglas Fox
Eileen M. Fox-Biswell, M.D.
Robert A. Frampton, M.D.
Michael O. Frank, M.D.
Kristin R. Frankfurt
Frankfurt-Short-Bruza Associates P.C.
Janet L. Franks
Robert R. Frantz Jr., M.D.
Roger A. Franz, M.D.
James R. Fraser, M.D.
Rodman A. Frates
Derrick C. Frazier
Lester Frazier
Coleen Frederick
Fried Kilpatrick Guinn LLC
Edward M. Fugate, M.D.
Jennifer C. Fugazzi
Thomas Fulbright
Charles G. Fullenwider, M.D.
Bennett E. Fuller, M.D.
Randy C. Fullerton, M.D.
Nedra R. Funk
Beverly W. Funke
Drs. Funnell & Strebel Inc.
Betty A. Furseth
Troy Fussell
Patricia A Gallagher
Reba Gallaspy
Tiffany Gallegos
The Galway Co.
Garber School District
Board of Education
Julie A. Garceau
Linda Gardner
Tricia D. Gardner
Ann T. Garrett
Linda D. Garrett
Nicholas D. Garrett
Vonna E. Garrett
Nina P. Gaugler
Nancy N. Gee
Timothy M. Geib, M.D.
Gerald I. Geiszler, M.D.
Kelly J. Geldmacher, M.D.
Gemini Industries Inc. Foundation
Genentech Foudation for Growth
Generali USA Life
Reassurance Company
Christine Gerdes
John W. Geurkink, M.D.
Richard T. Gieryn
Teri D. Gilbert
Judy M. Gilbreth, M.D.
Laurie Givens
Ondria C. Gleason, M.D.
Fabio Gobbo
Milton L. Godley, M.D.
Darren W. Goff, M.D.
Marilyn Goines
J. Michael Gold, M.D., P.A.
Karen Gold, M.D.
Marlene E. Gomes
Robert E. Gonce Jr.
Andrea R. Gonterman
Robin K. Gonzalez, M.D.
Jeffrey M. Goodloe, M.D.
Sean P. Goolsby
Vicki C. Gourley
Tom Grabe
Hugh C. Graham Jr., M.D.
Treva J. Graham, M.D.
Jerry H. Grant, M.D.
Jeffrey M. Grant, M.D.
Beverly J. Gray
John R. Gray Jr., M.D.
Patrick W. Gray, M.D.
Susan Q. Gray
David K. Green
Patricia N. Green
Virginia H. Greenberg
C. Fish Greenfield, M.D.
Anderson F. Greenhaw, M.D.
Lawrence J. Gregg, M.D.
Patricia A. Griffin
David W. Griffiths, M.D.
Gloria A. Grim, M.D.
Ziegfeld Dancer Medicine Donor Dies
Former Ziegfeld dancer Doris Eaton Travis dances with husband Paul H. Travis
at their home in Michigan. The couple established two endowed chairs
in the OU College of Medicine, one in surgery and the other in medicineendocrinology. Paul Travis died in 2000; Doris Travis died last spring at the
age of 106.
Doris Eaton Travis, the last surviving member of the legendary Ziegfeld Follies and co-creator of two endowed faculty
positions within the OU College of Medicine, died May 11 at
age 106 in Michigan.
The Paul H. and Doris Eaton Travis Chair in Thoracic Surgery
is held by Marvin Peyton, M.D., professor of surgery, and the
Paul H. and Doris Eaton Travis Chair in Endocrinology was held
by Ming-Hui Zou, M.D., Ph.D., professor of endocrinology.
Travis performed with the famous dance troupe from 1918,
when she was just 14, until 1920 and went on to star in musical
revues, Broadway comedies and silent films. She was the first
to perform the song, “Singin’ In the Rain,” written by Nacio
Herb Brown, with whom she had a long relationship.
In 1949, while operating an Arthur Murray dance studio in
Michigan, Travis met and married one of her dance pupils, Paul
Travis, an engineer who became wealthy from a doorjamb he
invented and used on many cars. They moved to Oklahoma
in 1970 and oversaw an 800-acre horse ranch. In her spare
time, Doris Travis earned a high school diploma, and at 88, a
bachelor’s degree from OU. Paul Travis died in 2000.
Doris Travis never retired. In recent years, she was regularly
featured in an annual Broadway AIDS benefit, most recently
in April, when she danced a few steps with the help of two
young and shirtless male dancers. After receiving rapturous
applause, she walked on her own off the stage.
The lights on Broadway dimmed in her honor when she
died a few weeks later.
[ FALL 2010 ]
PG. 63
Timothy L. Grode, M.D.
Louis J. Grosso
John W. Grudis, M.D.
Joseph B. Guarnaccia, M.D.
Bill Gumerson & Associates
Sheila K. Gunn, M.D.
Shannon H. Guss
Michael P. Gwartney, M.D.
H S B C - North America
Michele C. Hagan
Nelden W. Hagbom, M.D.
Dr. Brenda L. Haile
Carol R. Hall
Haley A. Hall
Julia L. Hall
Evelyn F. Halstied
John K. Hamilton, M.D.
Murray O. Hamilton, M.D.
Patti Hamilton
William C. Hamilton Jr., M.D.
Deborah E. Hammond, M.D.
Debra V. Hampton
Debra J. Handy
Linda C. Haneborg
Karl R. Hansen, M.D.
Mary A. Hansen
Kyle Hanser
Harold H. Haralson II, M.D.
Jean Harbison
Terri S. Hare
Joseph S. Hargis, M.D.
Ken Hargrove Jr.
Jane B. Harlow
Joe L. Harmon
The Harris Family Trust
Orlando C. Harris
Harrison Associates PC
H. Allen Harrison, M.D.
William S. Harrison, M.D.
David K. Harry, M.D.
David M. Harsha, M.D.
Keller Harvey
Cecil J. Hash, M.D.
Bradley G. Haskell, M.D.
Don W. Haskins, D.D.S.
Craig A. Haslam, M.D.
Ferdinand R. Hassler, M.D.
Karen L. Hauser
Josine Haustermanns
Winnie Hawkins
Dana A. Hayes
Jon T. Hayes
Terry Hayes, M.D.
Michael S. Haynes, M.D.
Dorothy R. Hearn
Reid D. Hebert
Gregory W. Heidrick, M.D.
Rona G. Heiliger
Robert L. Hemphill, M.D.
William M. Henderson, M.D.
Russell L. Hendrickson
James L. Hendrix, M.D.
Leslie B. Henegar
Steven L. Henslee, M.D.
Michael C. Hensley, M.D.
Brian H. Henson
Liane Herbst
Heritage Baptist
Robert E. Herndon, M.D.
Bob J. Herrin, M.D.
Richard J. Hess, M.D.
Cheryl A. Hewett
Kenneth A. Hieke, M.D.
William H. Hildebrand, Ph.D.
Bette J. Hill
Frank D. Hill
Lori W. Hill
Dr. Molly R. Hill
Timothy J. Hill, M.D.
Debby Hinrichs
Jerry Hire
Justin M. Hire
Deborah T. Hite
Cathleen Hodnett
Larry F. Hoefar
James C. Hoffman, M.D.
E. Peter Hoffman Jr.
Susan Hoffman
D. Randolph Hogan
Bob Hoke, M.D.
Ed Holcomb, D.D.S.
John H. Holcombe, M.D.
Holiday in the Heartland
James P. Holland, M.D.
LaVera A. Holland
MIchelle J. Holsclaw
Joyce Honey
J. William Hood, M.D.
Debra Hooper
Kimberly A. Horn
T. Karl Hoskison, M.D.
George J. Hotchko Jr., M.D.
John Houck, M.D.
Campbell P. Howard, M.D.
Dorothy F. Howell
Tay S. Howell, M.D.
Karen Howington
Rose M. Hoyt-Steele
Kristopher Hsu
Emily Y. Huang, M.D.
Terrie L. Hubbard
Joel B. Huber, M.D.
Hudiburg Auto Group
Lisa A. Hudson, M.D.
Robert J. Hudson
James C. Hudson
Huston Huffman Jr.
Shona Huffman
Lynn Hufnagel, M.D.
Kenneth V. Hughes III, M.D.
Sarah R. Hughes, M.D.
Martin R. Hullender Jr., M.D.
Terrill D. Hulson, M.D.
Francee A. Hume
John W. Hunt Living Trust
Elizabeth D. Hunter, M.D.
Kay A. Hurley
John R. Hurt
Carrie A. Hybels
Hannah Illig
International Lactation
Consultant Association
International Society of
Oncology Pharmacy Practio
Milagros G. Ireland
Winnie D. Jabara
R. Kern Jackson, M.D.
Lawrence A. Jacobs, M.D.
Mitch Jacobs
Chet H. Jameson III, M.D.
Carolyn R. Janney
Junie C. Janzen
Sandra Jarman
Charles A. Jennings, M.D.
Jodie L. Jerzyk
Mason P. Jett, M.D.
Sharon C. Jett
Ben A. Johnson
Doyle E. Johnson, M.D.
Kurt N. Johnson, M.D.
Lynn M. Johnson
Sarah Johnston
Shirley A. Johnson
Jason C. Joice, M.D.
Kevin L. Jolliff, M.D.
Brandon T. Jones
Calvin Jones
David I. Jones, M.D.
Kelly E. Jones, M.D.
JR Expressions LLC
Randall Juengel, M.D.
Jane Juergens
Peter S. Jungwirth, M.D.
Mark I. Jurras
Christine A. Kahr
David A Kallenberger, M.D.
John N. Kamphaus, M.D.
Paul J. Kanaly, M.D.
William E. Karnes, M.D.
Carol E. Kaspereit
Morris E. Katz, M.D.
Christian E. Kaufman Jr., M.D.
E. Chris Kauffman
Lee Ann Kaufman
John E. Kauth, M.D.
Vic Kearney
Debra L. Keefer
Judy A. Keeton
Jean R. Kelley
Judy Kelley
Kathleen C. Kelly
John W. Kemp
Christina E. Kendrick, M.D.
Marcy Kenney
Karen Kenworthy
Dr. Frank J. Kern
Joseph C. Kernke Jr.
Barbara L. Kerrick
Michael B. Kertok
John M. Kessinger, M.D.
George N. Keyser
Larry K. Killebrew, M.D.
Thomas E. Kimball, M.D.
Nellie Kimler
Bill King
Everett G. King, M.D.
Jeanne A. King, M.D.
Robert W. King Sr., M.D.
Eileen L. Kippen
Thomas J. Kirby
Stephen A. Kirkpatrick, M.D.
Abbas E. Kitabchi, M.D.
James B. Kite Jr.
Debbie Kline
Pamela A. Kline
Kelly H. Knecht
Mandy Knowles
Knutson Irrigation Design LLC
Joe Kobs
Margaret A. Kochenower
Norman S. Koehn, M.D.
Frederick P. Koontz
Jeanne L. Kopacka
Joseph A. Kopta, M.D.
Karen Kosel
Paul Kouri, M.D.
Roxann Krautkramer
Paul M. Krautter, M.D.
Rebecca Krepper
Michael D. Krieger, M.D.
Satish Kumar, M.D.
Thomas C. Kupiec, Ph.D.
H. T. Kurkjian, M.D.
Carol C. Kutteh, M.D.
L.L.F. Inc.
William F. La Fon, M.D.
Cheryl A. Lacey
Charles L. Lackey, M.D.
Tracey L. Lakin, M.D.
Kathy B. Lamprecht, M.D.
Michael L. Lanata
Rebecca Lane
Angela M. Langer-Heltzel
Brick A. Lantz, M.D.
Lawrence S. Lape
Gary L. Larson, M.D.
James E. Larson, M.D.
Sharon R. Latimer
Gideon T. Lau, M.D.
Charlette Laughlin
Elizabeth Laughlin
Gerald D. Laughlin
Dr. Monique M. Laughlin
Courtnay S. Leach
Joseph V. LeBlanc, M.D.
Marjorie A. Lee
James L. Leenstra, M.D.
Jason S. Lees, M.D.
Julie W. Lees, M.D.
Carol Janell Legg Trust
Elton W. LeHew Jr., M.D.
Mark Lere
Robert K. Lerner, M.D.
Charles A. Lester, M.D.
Mitchell W. Leventhal, M.D.
Martin Levine, M.D.
Mrs. Elaine Levy
Samantha J. Lewellen-Jackson, M.D.
Billie Lewis, M.D.
William K. Lieb
MaryAnn Lindberg
J. M. Lindsey, M.D.
Raymond A. List
Little River Energy Co.
Robert J. Livingston, D.D.S.
Rajko Ljutica
Franz A. Lobo
Deborah R. Loeffler
Ronald V. Loge, M.D.
Elizabeth London
William R. Loney, M.D.
Jeffrey L. Longwell
Lana L. Lopez
Ann Loudermilk, M.D.
Mrs. Jocelyn J. Love
Melissa Love
Rebecca Love
John M. Luber Jr.
Suzi M. Luckett
R. F. Lucy
Rebecca A. Luper, M.D.
George B. Lynch
The Doss and Kathryn Lynn Trust
Donna M. MacDonald
Katherine L. MacKellar
Macori, Inc.
Ashley A. Magness, M.D.
Marlene Magrini-Greyson, M.D.
Monty Magruder
Brennen Maki
Navara Malayaman, M.D.
Ann T. Malecha
Douglas K. Mandel, M.D.
Lawrence E. Mann, M.D.
Albert F. Mannel
Robert Mannel, M.D.
Badie S. Mansour, M.D.
Timothy B. Mapstone, M.D.
George C. Markert, M.D.
John W. Marks, M.D.
Melvin I. Marks, M.D.
Elwina A. Marlow
Marple Petroleum, LLC
Charles E. Marsh, M.D.
Donald W. Marsh, M.D.
Joseph L. Martin, M.D.
Mrs. Tracey J. Martin
Timothy L. Martin
Martindale Consultants Inc.
Mary K. Marvel
Dennis R. Mask, M.D.
Steve Mason
Stephen S. Matter, M.D.
Leslie L. Maxwell
Scott W. Maxwell, M.D.
Ronda May
James E. Mays Jr., M.D.
Robert A. McCabe Jr.
Mary E. McCaffrey-Duncan
Penny M. McCaleb
Charles A. McCall III
Cindy McCharen
Joni L. McClain, M.D.
Lottie F. McCormack
Kay McCracken
Gerald W. McCullough, M.D.
McCurdy Real Estate, Inc
James R. McCurdy, M.D.
Nancy N. McDonald
J. W. McDoniel, M.D.
Stacy D. McGinnis
William L. McHenry, M.D.
Susan P. McHugh
Kamryn McKeithen
Janet McLain
David L. McLaren, M.D.
John R. McMahan III, M.D.
Sherry G. McMasters
Dorothy G. McMurray, M.D.
John W. McReynolds, M.D.
Charles A. McWilliams
Cynthia C. McWilliams
M-D Building Products, Inc.
Denver W. Meacham II
Marc A. Meacham, M.D.
Marilyn M. Meade
Neva Meadows
Aneesh K. Mehta, M.D.
Mitchell S. Meier, M.D.
Herman Meinders
Steven A. Meixel, M.D.
Adrian S. Melissinos
Charles M. Mendenhall
Donna Meredith
Cindy H. Merrick
James A. Merrill, M.D.
Martha Merrill
Mrs. Harry Merson
Ron Merts
Joseph F. Messenbaugh III, M.D.
William H. Meyer, M.D.
Peter V. Meyers
Sandra K. Meyers
Mike Miers
Thomas D. Mihelich, M.D.
James C. Miles Jr., M.D.
Dan E. Miller, M.D.
Elnora G. Miller, M.D.
Karen L. Miller, M.D.
Kelly J. Miller
Marcia B. Pierce
Mary C. Miller
Ronald G. Miller
Ross H. Miller, M.D.
Sonya R. Miller, M.D.
Donna K. Milligan
Stephen C. Mills, M.D.
Jane Milsten
Marc S. Milsten, M.D.
Beatrice Miranda Vargas
Mary K. Mitchell
Joseph Mitro, M.D.
Mock Foundation
A. A. Mohammad, M.D.
Marian C. Monahan
Dorothy B. Monnet Living Trust
Kelly K. Moody
Marian J. Moon
John B. Moore Jr.
Troy O. Morgan Jr., M.D.
Richard E. Morris, M.D.
Astrid E. Morrison, M.D.
Doris A. Morrison
Shirley M. Morrison
Gary B. Morsch, M.D.
Martha R. Morse, M.D.
Jack W. Morton
Cheryl A. Moseley
Aaron Motola
Robert W. Moyer
Steven Mueller
Karen A. Mulkey
John J. Mulvihill, M.D.
Elizabeth W. Murphy
Thomas M. Murphy, M.D.
R. Clayton Musser, M.D.
William T. Myers
Naifco Realty Co.
Cindy Nami
Raja R. Nandyal, M.D.
NAPA of Kingfisher Inc.
N. Denise Nash
Robert O. Nathan, M.D.
Mary E. Nelson
Sharon F. Neuwald, Ph.D.
Mrs. Edward E. Newcomer
Harold J. Newman
Russ Newman
Trung B. Nguyen, M.D.
Jerry Nichols
Maurice C. Nickell, D.D.S.
Jeremy B. Nicoll
Margaret Norick
North Church
Leonard Northcutt
Sara Northwood
Ruth Norton
Elisa R. Norwood
Judy Oehlschlager
Aletha C. Oglesby, M.D.
OKC First Church of the Nazarene
Oklahoma Bankers Association
Oklahoma Electrical Supply Co.
The Oklahoma Horsemen's
Benevolent Trust
Oklahoma Medical Research Foundation
Oklahoma Racquetball Association
Milton C. Olsen, Ph.D.
Becky Olson
Darwin D. Olson, M.D.
Benton M. O'Neal Sr.
The Hon. Marian P. Opala
Robert D. Ornitz, M.D.
Orr Insurance
Clark Osborn
Edward W. Osborn, M.D.
Peyton E. Osborne, M.D.
Nancy C. Oster
Karla J. Oty
OU at San Diego Student
Nurses Association
OU IT Field Services
Mrs. Robin T. Owens
Gary L. Paddack, M.D.
Carol D. Padilla, M.D.
Amanda M. Paliotta
Andrea B. Palmer, M.D.
Blake W. Palmer, M.D.
Karl T. Palomino
Karen K. Pancheri
Kristen G. Pangburn
Alexander Pantaz
Papo d'Anjo Group Inc.
Jeffrey P. Pardee, M.D.
Mukesh T. Parekh, M.D.
David M. Parham, M.D.
David Park
Georgeann Park
Richard M. Parker
Reagan R. Parr, M.D.
Dr. Pamela P. Parrish
Barbara L. Parry, M.D.
Morgan W. Parry, M.D.
William L. Parry, M.D.
James L. Patterson Jr., M.D.
Kathleen B. Pattillo
Travis H. Patty
Robert R. Pavlu, M.D.
James C. Peck
Montgomery C. Peden, M.D.
William F. Peel III
Eliseo D. Perez
Elizabeth M. Perius
Wendy C. Perryman
Bea Persinger
Robert Petrick
Marvin D. Peyton, M.D.
Sandra J. Peyton
Phuong Pham
Physicians Relocation Services Inc.
James A. Pickens, M.D.
Lisa D. Pierce
William M. Pierce
Gary C. Pierson
Joseph P. Pineau, M.D.
Lynne Piper
John R. Pittman, M.D.
H. Craig Pitts, M.D
Loren Plotkin
Diana M. Pohlman
Edwin L. Pointer, M.D.
Barry H. Pollack, M.D.
Carol A. Poole
Trudy E. Posner
Russell G. Postier, M.D.
Ruthann Postier
David W. Potts, M.D.
Kent H. Potts, M.D.
Jan E. Powell
Kiran Prabhu, M.D.
Santosh T. Prabhu, M.D.
Precision Administrators Inc.
Janet B. Price
John E. Prichard, M.D.
Bob Priest, M.D.
Martin Propp
Tony G. Puckett, M.D.
William R. Puffinbarger, M.D.
Catherine Quinlan
Mark F. Quinn
Roger D Quinn, M.D.
Craig H. Rabb, M.D.
Susan K. Radike
Kristen Radka
Rosalie Rahe
Leslie J. Rainbolt-Forbes, M.D.
Vadakepat Ramgopal, M.D.
Sherri L. Ranson
Jerry K. Rasmussen
Geraldine Raupe
Raytheon
Larry V. Reavis
Harold R. Reed
Michelle M. Reid
Robert E. Remis, M.D.
Diana K. Renouard
Philip J. Rettig, M.D.
Jenni M. Reuter
John F. Revelis, M.D.
Berta F. Rex
Robert Rhoads
Michaelene R. Ribbeck, Ph.D.
Apple N. Rice, M.D.
Sam Rice, M.D.
Alfonso Richards, M.D.
Charles C. Richards
Karen L. Richards
Vicki Richards
Renee Richardson
Charlotte Richels
Brian J. Richmand
Carol Ricks
Harold S. Riggs
William G. Riley Life Estate
Audray M. Riva
Brenda Roach
Bill D. Roberts
David N. Roberts, M.D.
John P. Roberts, M.D.
Pamela R. Roberts. M.D.
Claudia B. Robertson
Ann Robinson
Linda J. Robinson
Patrick A. Robinson, M.D.
Gordon Robson, D.O.
Suzanne K. Rodgers
Roess, LLC
Nancy Rooks
In bold-face type are names of OU President’s Associates who designate the College of Medicine as beneficiary of their annual membership gifts.
[ FALL 2010 ]
PG. 65
RoseRock Bank
Linda E. Ross
Russell B. Roth, M.D.
Kerry Rothschild
Arthur W. Rousseau, M.D.
Adam E. Rowe
Donna R. Rowlan
Elizabeth Rowland
Larry J. Roy, M.D.
RST Restaurant LLC
Glenn J. Rubin, M.D.
Theodore A. Ruff, M.D.
Patricia S. Ruffin
David S. Russell, M.D.
Lana G. Russell
Rutherfurd Children's Trust
Teresa Rutledge, M.D.
Karen L. Ryan
Ronald B. Saizow, M.D.
Alix Samara
E. N. Scott Samara, M.D.
James M. Samis
Lynn Y. Samis
Michael Samis
Venusto H. San Joaquin, M.D.
Larry J. Sanders, M.D.
Mike Sanders
Ildiko M. Sandford, M.D.
Isabel Sanditen
Vivian F. Sangunett
William W. Savage III
Anita K. Schell
Catherine C. Schmidt, M.D.
Herb R. Schmidt
Pattie K. Schrader
Kimberly A. Schrage, M.D.
Linda S. Schulz
Steven C. Schultz Jr., M.D.
Heidi M. Schuster
Timothy P. Schweitzer, M.D.
Gloria F. Scott
Susie Scott
Rachel M. Seaman, M.D.
John R. Seelye
Goz Segars
Kathy N. Seibold
Jeary Seikel
Angela L. Selmon, M.D.
Janet Selvidge
Kent A. Sepkowitz, M.D.
Vanessa Sepulveda-Catinchi, M.D.
Christopher C. Shadid, M.D.
Derek J. Shadid, M.D.
James T. Shaeffer, M.D.
James G. Shafer
Johanna Shapiro, PhD
Jo Ann Sharp
R. Douglas Shaw, M.D.
Dr. Roger E. Sheldon
Shell Oil Company Foundation
R. M. Shepard Jr., M.D.
Cynthia J. Shepherd
Lauren Sherman
Milton B. Shields, M.D.
Beverly K. Shipman
Richard W. Shoffner, M.D.
Shook, Hardy & Bacon LLP
Shorty's Caboy Hattery Inc.
Shelley D. Shoun
Ronald W. Shreck, M.D.
Mary S. Shuman, M.D.
Philip S. Shurley, P.A.
Sickle Cell Cure Foundation
Ami L. Siems, M.D.
Sanjay K. Sikka, M.D.
Francine Silver
Donald R. Simmons, M.D.
Barbara Simons
Rachael Singer
Richard A. Singer
Patricia K. Singley
Stefanus Siswanto, D.D.S.
Mrs. Floyd E. Skarky
J. Craig Skinner
Gregory L. Skuta, M.D.
Stanley Slater, M.D.
Tim K. Smalley, M.D.
Charles G. Smart
Bobby Smith
Christopher J. Smith
Connie Smith
Elmer Smith Trust
Dr. Harrison M. Smith II
James W. Smith, M.D.
Justine D. Smith
Karen M. Smith
Katherine M. Smith, M.D.
Kelly A. Smith
Lee Allan Smith
Mike T. Smith
Richard H. Smith
Steven O. Smith, M.D.
Cheryl A. Snyder
Southwestern Christian Church
Amy L. Sparkman
Linda L. Speegle
Robert T. Spencer, M.D.
Garth L. Splinter, M.D.
Sports Imports
Christine S. Spradling Trust
St. Joseph's Church
Carl C. Stacy, M.D.
Joseph W. Stafford Jr., M.D.
Joseph W. Stafford Sr., M.D.
Gregory S. Stamps, M.D.
Phil Stamps, M.D.
James E. Stanfield, M.D.
Bryan E. Stanhouse, Ph.D.
Myrtle Statton
Elizabeth A. Steakley
Stealth Volleyball Club Inc.
Robert D. Steele
Judith C. Steelman
Keely G. Steger
Annie Steiger
Elsie J. Stewart
Jane M. Stewart
Stillwater National Bank
Michael J. Stirling, M.D.
Lilly A. Stone
Sarah Stone
Stringer Family Foundation
Stubbs Resources Account
Walter S. Stullman, M.D.
Anthony L. Suchman
Samer Suleiman, M.D.
Helen Sullivan
J. Andy Sullivan, M.D.
Erin Sullivan-Theisen
Michael L. Suminski, M.D.
Joy E. Summers-Ables
Robert E. Swatek
William W. Symes
Thomas E. Talley, M.D.
Glenna Tanenbaum
Juliana Tanenbaum
John R. Tassey, PhD
Judy Tatman
Taylor, Burrage, Foster et al
Betsy J. Taylor, M.D.
Clayton Taylor
Maria Taylor
Richard G. Taylor
Robert A. Taylor, M.D.
Christina M. Teague
Patrick Teer, M.D.
Temtrol
Ms. Jennifer L. Thielen
Third Degree Advertising
Cathrine S. Thomas
John A. Thomas, M.D.
Adriana A. Thompson
Allison Heather M. Thompson, M.D.
Donald C. Thompson, M.D.
Jane Thompson
Roger A. Thompson, M.D.
Roy L. Thompson, M.D.
Stephen Thompson
Kathleen Thornton
THS Class of 1957
Becky Tidwell
Thomas D. Tinker, M.D.
Ragu S. Tirukonda
Susan Titus
Kimberly A. Tkach
Stephen Tkach, M.D.
Thomas K. Tkach, M.D.
Galen B. Toews, M.D.
James R. Tolbert
Theodore A. Tolentino, M.D.
Michael B. Tolson
Janice Tona
James A. Totoro, M.D.
Tower Cafe Inc.
Larry Trachtenberg
Breca S. Tracy, Ph.D.
Michael C. Tramontana
Khanh P. Tran, M.D.
Richard P. Trautman, M.D.
Dr. Jess M. Trevino
Chris Tribble
Debra D. Trimble
William E. Trousdale, M.D.
N. Phillip Truss III
Sydney S. Tucker
Tulsa Chinese Christian Church
Jennifer R. Turner
Susan Turner
Stephen Twyman
Lori B. Tyler
Shelly S. Ulm
UMB Bank
United Way
Bret A. Unterschuetz
Ashwini K. Vaidya, M.D.
Atul M. Vaidya, M.D.
Sarah E. Van Stone
Vantage Open MRI LLC
Rene Vassar
Susan M. Vater
Virginia Vaughan, M.D.
Daniel L. Vaughn, M.D.
Wanda J. Venters, M.D.
Margo S. Von Schlageter, M.D.
Sarah Waite Scutt
Jackie Waldron
Joan L. Walker, M.D.
Roger D. Walker, M.D.
Mrs. Helen F. Wallace
Ms. Jennifer L. Wallace
Ms. Victoria C. Wallace
Mr. Steven C. Walling
Mr. Patrick Walsh
Daniel G. Walters, M.D.
Ann L. Ward, M.D.
Dr. Thomas A. Warm
Clarence E. Warner
Anthony G. Warren
Bradley V. Watts, M.D.
Weaver & Woodbery Co.
Dale I. Webb, M.D.
Jean Webb
Robert A. Webber
David B. Wechsler
Roger E. Wehrs, M.D.
Larry W. Weidner, M.D.
Harriet V. Weil
Michael A. Weisz, M.D.
A. Max Weitzenhoffer Jr.
James H. Wells, M.D.
Amy R. Westbrock, M.D.
Ellen J. Wheeler
Nancy J. Wheeler
Thomas W. White, M.D.
Denise Whitly
Daphne T. Whitman
Robert J. Wienecke, M.D.
Don L. Wilber, M.D.
Wild Card Commercial Realty LLC
Susan H. Wiley
Elaine M. Wilkerson
Matha Wilkerson
Karen Wilks, M.D.
Elwood F. Williams Jr., M.D.
Gregory P. Williams, M.D.
Martha V. Williams
Wilmes Super Store, Inc.
Janice L. Wilner
Carla E. Wilsey, M.D.
Wilson Public School
Bethany A. Wilson
Donna R. Wilson
Michael R. Wilson, M.D.
Peter Winn, M.D.
Gary W. Winsett
Cranfill K. Wisdom, M.D.
Peggy J. Wisdom, M.D.
Richard E. Witt, M.D.
Brute Wolf
Mark Wolraich, M.D.
Womens Professional
Rodeo Association Inc.
David K. Wong, M.D.
C. David Wood, M.D.
Mark W. Wood, M.D.
Kay H. Woods
Mrs. Leigh Woody
Anne W. Workman
Kristine D. Wyatt
Janice L. Yancey
William H. Yarborough, M.D.
Pamela Yates
Nancy P. Yoch
Harold Yocum, M.D.
Debbie L. Yoeckel
C. Dean York
Richard M. Young, M.D.
Stanton L. Young
Don T. Zachritz
Daniel Zeligson
Ronald A. Zent, M.D.
Alumni Donors by Class
1937
William F. La Fon, M.D.
1941
Robert W. Florence, M.D.
Morris E. Katz, M.D.
Richard E. Witt, M.D.
1943
Charles S. Graybill, M.D.
John A. McIntyre, M.D.
1944
Robert J. Morgan, M.D.
Dr. Pamela P. Parrish
Robert D. Shuttee, M.D.
1945
C. W. Arrendell Jr., M.D.
J. T. Brooks, M.D.
Paul Kouri, M.D.
Dorothy G. McMurray, M.D.
J. Harold Tisdal, M.D.
1946
Elnora G. Miller, M.D.
Ross H. Miller, M.D.
1947
Edward M. Fugate, M.D.
William J. Hemphill, M.D.
James L. Patterson Jr., M.D.
Darwin L. Richardson, M.D.
1948
Robert E. Herndon, M.D.
Marvin K. Margo, M.D.
1949
David R. Brown, M.D.
1950
Robert W. King Sr., M.D.
1951
Anne C. Courtright, M.D.
1952
Duane A. Barnett, M.D.
Charles E. Beck, M.D.
Col. Arthur W. Buswell, M.D.
Marion D. Christensen, M.D.
Ted Clemens Jr., M.D.
Milton L. Godley, M.D.
1953
William S. Harrison, M.D.
Clarence B. Pinkerton, M.D.
Donald J. Sheffel, M.D.
1954
Thomas E. Douthit Jr., M.D.
Robert E. Engles, M.D.
Lawrence E. Mann, M.D.
John W. Marks, M.D.
Charles E. Marsh, M.D.
Gerald W. McCullough, M.D.
Joseph W. Stafford Sr., M.D.
1955
A. M. Arky, M.D.
Otis F. Burris, M.D.
James G. Coldwell, M.D.
Jim G. Duckett, M.D.
Ferdinand R. Hassler, M.D.
Bob J. Herrin, M.D.
William E. Karnes, M.D.
Norman J. Schultz, M.D.
Daniel L. Vaughn, M.D.
Cranfill K. Wisdom, M.D.
1956
Kenneth H. Cooper, M.D.
Joseph Harroz, M.D.
J. W. McDoniel, M.D.
Floyd F. Miller, M.D.
J. Charles Monnet, M.D.
Troy O. Morgan Jr., M.D.
Edwin L. Pointer, M.D.
David L. Sockler, M.D.
Theodore W. Violett, M.D.
Robert G. White, M.D.
1957
James A. Crabtree, M.D.
J. William Hood, M.D.
Oliver W. Jones Jr., M.D.
Sammy H. Kouri, M.D.
Victor R. Neal, M.D.
F. E. Webb Jr., M.D.
1958
William G. Bernhardt, M.D.
David W. Bishop, M.D.
Sylvia S. Bottomley, M.D.
C. Maurice Coffey, M.D.
Bob Hoke, M.D.
Harry C. Holloway Jr., M.D.
W. E. Maldonado, M.D.
Donald W. Marsh, M.D.
Joseph F. Messenbaugh III, M.D.
1959
Merle D. Carter, M.D.
B. D. Dotter, M.D.
James W. Dyer, M.D.
John H. Gardner, M.D.
Doyle E. Johnson, M.D.
Billie Lewis, M.D.
1960
Donald R. Carter, M.D.
Thomas J. Honea, M.D.
Don Karns, M.D.
George C. Markert, M.D.
1961
E. W. Allensworth, M.D.
Roger A. Franz, M.D.
1962
Jerry B. Blankenship, M.D.
Ronald C. Elkins, M.D.
Charles C. Elliott, M.D.
David A. Flesher, M.D.
Everett G. King, M.D.
Joseph A. Kopta, M.D.
H. Craig Pitts, M.D
Tony G. Puckett, M.D.
Michael H. Whalen, M.D.
Thomas L. Whitsett, M.D.
1963
Thomas C. Alexander, M.D.
R. Timothy Coussons, M.D.
J. Patrick Evans, M.D.
Richard E. Morris, M.D.
Robert E. Ringrose, M.D.
Don A. Rockwell, M.D.
David S. Russell, M.D.
Phil Stamps, M.D.
H. Keith Stonecipher, M.D.
Larry W. Weidner, M.D.
1964
Richard J. Allgood, M.D.
Bruce L. Evatt, M.D.
Bruce A. Naylor, M.D.
Bob Priest, M.D.
Ronald R. Sheets, M.D.
Tim K. Smalley, M.D.
Daniel R. Stough, M.D.
Walter S. Stullman, M.D.
Thomas E. Talley, M.D.
Robert A. Taylor, M.D.
Dale I. Webb, M.D.
1965
Chuck Blair, M.D.
John R. Bozalis, M.D.
Martin R. Hullender Jr., M.D.
Abbas E. Kitabchi, M.D.
Robert R. Pavlu, M.D.
Kent H. Potts, M.D.
A. J. Reed, M.D.
Sam Rice, M.D.
Ildiko M. Sandford, M.D.
Gary F. Strebel, M.D.
1966
Roy E. Camp, M.D.
Robert G. Case, M.D.
Glenn R. Cunningham, M.D.
John W. Geurkink, M.D.
Robert L. Hemphill, M.D.
James R. Lucas, M.D.
Happy Mullican, M.D.
John F. Schuhmacher, M.D.
James T. Shaeffer, M.D.
Milton B. Shields, M.D.
Jan T. Turley, M.D.
1967
Judith S. Asher, M.D.
Edwin F. Ellis, M.D.
Joe B. Harbison, M.D.
Christian E. Kaufman Jr., M.D.
Robert J. Weedn, M.D.
1968
Harrison G. Butler III, M.D.
Stephen B. Campbell, M.D.
David A. Cross, M.D.
Phyllis P. Engles, M.D.
Donald H. Garrett, M.D.
Thomas D. Harris, M.D.
Elton W. LeHew Jr., M.D.
Thomas M. Murphy, M.D.
E. N. Scott Samara, M.D.
Hal B. Vorse, M.D.
Kenneth W. Whittington, M.D.
1969
Dennis W. Coffman, M.D.
Walter C. Dandridge Jr., M.D.
William M. Henderson, M.D.
Lawrence A. Jacobs, M.D.
Larry K. Killebrew, M.D.
Dennis R. Mask, M.D.
James R. McCurdy, M.D.
Dan E. Miller, M.D.
Gabriel A. Shapiro, M.D.
1970
M. Dewayne Andrews, M.D.
Sinclair W. Armstrong Jr., M.D.
Jack J. Beller, M.D.
Jay P. Cannon, M.D.
James D. Dixson, M.D.
R. Nathan Grantham, M.D.
Lawrence J. Gregg, M.D.
Lynn H. Harrison Jr., M.D.
Stephen W. Haskew, M.D.
Carl T. Hook, M.D.
Fred M. Hurst Jr., M.D.
Norman K. Imes Jr., M.D.
Stephen C. Mills, M.D.
Lee E. Schoeffler, M.D.
R. Douglas Shaw, M.D.
Michael L. Stratton, M.D.
1971
David W. Bank, M.D.
Charles F. Bethea, M.D.
Philip C. Bird, M.D.
David J. Confer, M.D.
J. L. Dunagin Jr., M.D.
Robert A. Frampton, M.D.
John K. Hamilton, M.D.
Mitchell W. Leventhal, M.D.
Robert D. Ornitz, M.D.
Marvin D. Peyton, M.D.
Galen B. Toews, M.D.
Richard P. Trautman, M.D.
1972
Duane A. Burroughs, M.D.
William H. Downham, M.D.
Michael O. Frank, M.D.
William C. Hamilton Jr., M.D.
Joseph S. Hargis, M.D.
R. Kern Jackson, M.D.
Zev M. Kahn, M.D.
John M. Kessinger, M.D.
Dr. John W. McReynolds, M.D.
Peyton E. Osborne, M.D.
John W. Tipton, M.D.
Roger D. Walker, M.D.
Daniel G. Walters, M.D.
Peggy J. Wisdom, M.D.
John J. Zavoshy, M.D.
In bold-face type are names of OU President’s Associates who designate the College of Medicine as beneficiary of their annual membership gifts.
[ FALL 2010 ]
PG. 67
1973
Ron J. Anderson, M.D.
William C. Burnett, M.D.
Ralph C. Emmott, M.D.
John H. Holcombe, M.D.
Thomas E. Kimball, M.D.
Walter L. Lamar, M.D.
Edward W. Osborn, M.D.
J. Randall Rauh, M.D.
James H. Schmidt, M.D.
1974
Dian Y. Denney, M.D.
G. Kevin Donovan, M.D.
C. Douglas Folger, M.D.
Michael S. Haynes, M.D.
Campbell P. Howard, M.D.
Paul J. Kanaly, M.D.
Larry J. Sanders, M.D.
William E. Trousdale, M.D.
James G. Webb, M.D.
Gregory P. Williams, M.D.
Carla E. Wilsey, M.D.
1975
Phillip Barrett, M.D.
Michael J. Brantley, M.D.
Julian V. Deese, M.D.
Jeffrey G. Hirsch, M.D.
James C. Hoffman, M.D.
James P. Holland, M.D.
John H. Holliman, M.D.
David A Kallenberger, M.D.
Gideon T. Lau, M.D.
Thomas A. Marberry, M.D.
Dr. Jeffrey P. Pardee
Larry R. Pennington, M.D.
Russell G. Postier, M.D.
David W. Potts, M.D.
Michael J. Stirling, M.D.
James A. Totoro, M.D.
Jerry B. Vannatta, M.D.
Michael L. Winzenread, M.D.
1976
Patricia A. Barnes, M.D.
John P. Cheatham, M.D.
Glenn P. Dewberry Jr., M.D.
John C. England, M.D.
Jo Ann Spiegel Harris, M.D.
George J. Hotchko Jr., M.D.
Terrill D. Hulson, M.D.
Richard H. Jackson, M.D.
Kennon L. Kuykendall, M.D.
Ronald V. Loge, M.D.
Robert C. Newman, M.D.
Ronald W. Shreck, M.D.
Ann L. Ward, M.D.
Randal S. Weber, M.D.
1977
Dr. Jeffrey A. Cohen
John J. Coyle Jr., M.D.
Michael A. Crews, M.D.
Lynda M. Dickerson-Khouzam, M.D.
James R. Fraser, M.D.
Glen R. Fuller, M.D.
Gerald I. Geiszler, M.D.
Deborah E. Hammond, M.D.
Joel B. Huber, M.D.
Craig H. Lubin, M.D.
J. Steve Miller, M.D.
Robert O. Nathan, M.D.
Morgan W. Parry, M.D.
Eugene A. Steinberg, M.D.
Ted E. Webb, M.D.
William H. Yarborough, M.D.
1978
James M. Blalock, M.D.
Jerry D. Brindley Jr., M.D.
Robert M. Clark, M.D.
Paul C. Cochran, M.D.
Mark S. Cotner, M.D.
Douglas G. Cox, M.D.
Franklin C. Davis, M.D.
Paul M. Finer, M.D.
John R. Gray Jr., M.D.
Timothy L. Grode, M.D.
Chet H. Jameson III, M.D.
Robert G. Johnson, M.D.
Jeanne A. King, M.D.
Charles L. Lackey, M.D.
Aletha C. Oglesby, M.D.
Barbara L. Parry, M.D.
Arthur W. Rousseau, M.D.
Glenn J. Rubin, M.D.
Don L. Wilber, M.D.
1979
Gordon E. Alldrin, M.D.
Debra K. Barns, M.D.
Steven L. Henslee, M.D.
Timothy J. Hill, M.D.
Marc F. Inciardi, M.D.
James E. Larson, M.D.
William L. McHenry, M.D.
Richard W. Shoffner, M.D.
Randall J. Willis, M.D.
Richard M. Young, M.D.
1980
Steven M. Babin, M.D.
Peter D. Binstock, M.D.
Christopher M. Boxell, M.D.
Reagan H. Bradford Jr., M.D.
Terry N. Brown, M.D.
Frank R. Burton, M.D.
Mary S. Burton, M.D.
J. Christopher Carey, M.D.
Helen L. Corcoran, M.D.
Christopher G. Covington, M.D.
David L. Dautenhahn, M.D.
Justine C. Dautenhahn, M.D.
Barry R. Eisen, M.D.
Warren L. Felton III, M.D.
Harold H. Haralson II, M.D.
Terry Hayes, M.D.
Michael D. Krieger, M.D.
Kathy B. Lamprecht, M.D.
David L. McLaren, M.D.
Mojtaba Moghadam, M.D.
Gary B. Morsch, M.D.
Martha R. Morse, M.D.
John R. Pittman, M.D.
Barry H. Pollack, M.D.
Ronald B. Saizow, M.D.
Kent A. Sepkowitz, M.D.
R. Brent Smith, M.D.
Carl C. Stacy, M.D.
Joseph W. Stafford Jr., M.D.
Charles M. Swaney, M.D.
Wanda J. Venters, M.D.
Ronald A. Zent, M.D.
1981
John R. Ashley, M.D.
David M. Bailey, M.D.
Brian G. Birdwell, M.D.
Gregory R. Campbell, M.D.
Andrew J. Dodge, M.D.
Kathleen A. Glaze, M.D.
Kim R. Hauger, M.D.
Peter S. Jungwirth, M.D.
Donald J Kastens, M.D.
Gary L. Larson, M.D.
Lora J. Larson, M.D.
Robert K. Lerner, M.D.
Ann Loudermilk, M.D.
Marlene Magrini-Greyson, M.D.
John R. McMahan III, M.D.
Thomas D. Mihelich, M.D.
John H. Saxon III, M.D.
Thomas W. White, M.D.
Ervin S. Yen, M.D.
1982
Ronnie D. Brownsworth, M.D.
Mark C. Burr, M.D.
Susan L. Chambers, M.D.
Larry K. Chase, M.D.
John P. Clemons, M.D.
Russell D. Crain, M.D.
S. Edward Dakil II, M.D.
John K. Doyle, M.D.
John M. Flack, M.D., M.P.H.
Patrick W. Gray, M.D.
Michael P. Gwartney, M.D.
Charles A. Jennings, M.D.
David I. Jones, M.D.
Stephen A. Kirkpatrick, M.D.
Mary S. Maxwell, M.D.
Marc A. Meacham, M.D.
Karen L. Miller, M.D.
Montgomery C. Peden, M.D.
Robert E. Remis, M.D.
Mark A. Riner, M.D.
Stephen L. Styron, M.D.
Rebecca J. Swaney, M.D.
1983
Phillip G. Doerner, M.D.
William K. Drell, M.D.
Gene R. Fuller, M.D.
Lynn Hufnagel, M.D.
Stephen S. Matter, M.D.
Joni L. McClain, M.D.
Larry J. Roy, M.D.
William T. Turner, M.D.
1984
Mary L. Blumberg, M.D.
Deborah S. Boyer, M.D.
Randy C. Fullerton, M.D.
Sheila K. Gunn, M.D.
Don L. Henslee, M.D.
Garth L. Splinter, M.D.
Thomas D. Tinker, M.D.
Elwood F. Williams Jr., M.D.
1985
John M. Brookey, M.D.
Richard G. Chesler, M.D.
Kerry R. Clark, M.D.
David J. Flesher, M.D.
Dr. David W. Griffiths
Susan M. Harmon, M.D.
David K. Harry, M.D.
Elizabeth D. Hunter, M.D.
John N. Kamphaus, M.D.
Norman S. Koehn, M.D.
Brick A. Lantz, M.D.
Robert L. Overacre, M.D.
John A. Owen, M.D.
Carol D. Padilla, M.D.
Richard A Ruffin, M.D.
Brian D. Ryals, M.D.
Phebe M. Tucker, M.D.
Virginia Vaughan, M.D.
1986
James M. Baker, M.D.
Joan P. Cain, M.D.
Lisa Dobberteen, M.D.
Bennett E. Fuller, M.D.
Keith E. Gawith, M.D.
Mark H. Gillie, M.D.
James L. Hendrix, M.D.
David H. Jelley, M.D.
Garlanda L. Parker-Hughey, M.D.
Robert T. Spencer, M.D.
Arthur F. Windholz, M.D.
David K. Wong, M.D.
1987
Gerald S. Asin, M.D.
Stephen A. Feuerborn, M.D.
Joseph B. Guarnaccia, M.D.
David M. Harsha, M.D.
Carol C. Kutteh, M.D.
Scott W. Maxwell, M.D.
David J. Mullen, M.D.
Spencer I. Rozin, M.D.
Eleatha L. Surratt, M.D.
1988
Deborah S. Blalock, M.D.
Lisa A. Hudson, M.D.
Douglas K. Mandel, M.D.
Mitchell S. Meier, M.D.
Nancy E. O'Dell, M.D.
Craig H. Rabb, M.D.
Angela L. Selmon, M.D.
Ami L. Siems, M.D.
Roger A. Thompson, M.D.
Michael A. Weisz, M.D.
C. David Wood, M.D.
Mark W. Wood, M.D.
1989
Linda B. Andrews, M.D.
Sally Berger, M.D.
Charles B. Bowman, M.D.
Timothy J. Brennan, M.D.
Norvell V. Coots, M.D.
Kenneth V. Hughes III, M.D.
Rhett L. Jackson, M.D.
Robert N. Jarman, M.D.
Charles A. Lester, M.D.
Mark R. Miller, M.D.
Marc S. Milsten, M.D.
Lorenz T. Ramseyer, M.D.
Nabil E. Srouji, M.D.
Laurie S. Swaim, M.D.
Thomas K. Tkach, M.D.
1990
Paul C. Bierig, M.D.
Michelle A. Boice, M.D.
C. Fish Greenfield, M.D.
James C. Miles Jr., M.D.
Joseph P. Pineau, M.D.
Denise D. Shaw, M.D.
Kirk D. Stites, M.D.
Daron G. Street, M.D.
Donald C. Thompson, M.D.
1991
Judy M. Gilbreth, M.D.
Astrid E. Morrison, M.D.
Lynne V. Ozinga, M.D.
William R. Puffinbarger, M.D.
John P. Roberts, M.D.
Gregory S. Stamps, M.D.
1992
Jonathan E. Drummond, M.D.
Patricia G. Fenderson, M.D., Ph.D.
Greg A. Krempl, M.D.
Thomas W. Tryon, M.D.
Bradley V. Watts, M.D.
1993
Sharon L. Barber, M.D.
Tuan-A D. Diep, M.D.
Jerry H. Grant, M.D.
Gloria A. Grim, M.D.
Tay S. Howell, M.D.
Kevin W. Miller, M.D.
Vanessa Sepulveda-Catinchi, M.D.
William E. Stringer, M.D.
Khanh P. Tran, M.D.
1994
Tate B. Allen, M.D.
Mark A. Dawkins, M.D.
Karen Gold, M.D.
Sonya R. Miller, M.D.
Reagan R. Parr, M.D.
Nestor F. Pinaroc, M.D.
Leslie J. Rainbolt-Forbes, M.D.
Gina L. Ressler, M.D.
Steven O. Smith, M.D.
Laura M. Young, M.D.
1995
Bradley D. Carter, M.D.
Tina Marie Cooper, M.D.
Paul L. Firth, M.D.
Samantha J. Lewellen-Jackson, M.D.
Robert W. Maxwell, M.D.
Michael L. Suminski, M.D.
W. Chris Sutterfield, M.D.
Karen E. Wilks, M.D.
Robert B. Wilson II, M.D.
1996
Janice L. Bazarian, M.D.
David W. Bobb, M.D.
Christopher S. Candler, M.D.
Robert R. Frantz Jr., M.D.
Michael J. Hahl, M.D.
Dr. Murray O. Hamilton, M.D.
Glen A. Henry, M.D.
Emily Y. Huang, M.D.
Christopher A. Paskowski, M.D.
John F. Revelis, M.D.
Mary S. Shuman, M.D.
1997
Virginia D. Burdine, M.D.
Justin D. Digby, M.D.
Marianne E. Dunlap, M.D.
Mark A. Fergeson, M.D.
Karl R. Hansen, M.D.
Daniel P. Hill, M.D.
Jonathan A. Tarpley, M.D.
1998
H. Allen Harrison, M.D.
Michael H. Hennessey, M.D.
Michael C. Hensley, M.D.
Bretton H. Jameson, M.D.
Jason S. Lees, M.D.
Rebecca A. Luper, M.D.
Ashley A. Magness, M.D.
Apple N. Rice, M.D.
Steven V. Richards, M.D.
Steven C. Schultz Jr., M.D.
Michael S. Smith, M.D.
Sidney D. Treat, M.D.
Atul M. Vaidya, M.D.
Robert J. Wienecke, M.D.
1999
James T. Banta, M.D.
Virginia F. Casey, M.D.
Shouvik Chakrabarty, M.D.
Sami S. Dahr, M.D.
Treva J. Graham, M.D.
Elizabeth A. Jett, M.D.
Kurt N. Johnson, M.D.
Robert J. Lockwood, M.D.
Kimberly A. Schrage, M.D.
Timothy P. Schweitzer, M.D.
Derek J. Shadid, M.D.
Donald R. Simmons, M.D.
Ashwini K. Vaidya, M.D.
Todd C. Villines, M.D.
Thienkhai H. Vu, Ph.D., M.D.
2000
Todd S. Barlow, M.D.
DeJean L. Dace, M.D.
Amanda D. Delahay, M.D.
David M. Delahay, M.D.
Jason C. Graff, M.D.
Bradley G. Haskell, M.D.
Christina E. Kendrick, M.D.
Stacie R. Lane, M.D.
Julie W. Lees, M.D.
R. Clayton Musser, M.D.
Julie A. Schaufele, M.D.
Christopher C. Shadid, M.D.
Sanjay K. Sikka, M.D.
Amy R. Westbrock, M.D.
2001
William C. Blackledge, M.D.
Robin K. Gonzalez, M.D.
Mercy M. Hylton, M.D.
Kelly E. Jones, M.D.
Trang D. Nguyen, M.D.
Betsy J. Taylor, M.D.
Allison Heather M. Thompson, M.D.
Roy L. Thompson, M.D.
2002
Chad L. Betts, M.D.
Bobby L. Boyanton, M.D.
James M. Evans, M.D.
Timothy M. Geib, M.D.
Kelly J. Geldmacher, M.D.
Stephanie C. Grim, M.D.
Jason C. Joice, M.D.
James L. Leenstra, M.D.
Douglas C. Miller, M.D.
David A. Salikof, M.D.
2003
Sharon E. Carswell, M.D.
James R. Earley, M.D.
Kristy L. Jones, M.D.
Edgar L. LeClaire, M.D.
Aneesh K. Mehta, M.D.
David N. Roberts, M.D.
James E. Stanfield, M.D.
2004
Stephen D. Confer, M.D.
Anderson F. Greenhaw, M.D.
Jason G. Holman, M.D.
Sarah R. Hughes, M.D.
Kevin L. Jolliff, M.D.
Eric W. Raasch, M.D.
Stephanie D. Schniederjan, M.D.
Rachel M. Seaman, M.D.
David W. Shepherd, M.D.
Katherine M. Smith, M.D.
2005
Dianne M. Augelli, M.D.
Steven P. Brantley, M.D.
Jordan C. Deschamps-Braly, M.D.
Craig A. Haslam, M.D.
Laura G. Hensley, M.D.
Navara Malayaman, M.D.
Andrea B. Palmer, M.D.
Blake W. Palmer, M.D.
Ryan T. Skinner, M.D.
John A. Thomas, M.D.
2006
Branson R. Kester, M.D.
2008
John S. Long Jr., M.D.
Janet H. Pollard, M.D.
Sarah M. Smith, M.D.
To discuss ways to support the OU College of Medicine
today − or in the future through your planned gift −
please contact the Office of Alumni and Development,
(405) 271-2300.
In bold-face type are names of OU President’s Associates who designate the College of Medicine as beneficiary of their annual membership gifts.
[ FALL 2010 ]
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Nearly one-third of Oklahoma high schools kicked off the school year with Win-Win Week, an initiative of the OU Cancer Institute to encourage student-led
cancer prevention and fundraising programs. Announcing the program at Norman High School are, from left, OU Heisman Trophy winner Steve Owens, Duncan
High School cheerleader Chandler Hudson, Norman High School Student Congress President Sarah Hartley, Pawhuska High School Student Council President
Logan Shuping and OU Heisman Trophy winners Billy Sims and Jason White. Oklahoma's First Lady Kim Henry also promoted Win-Win Week, a component of
OUCI's Oklahoma Students Care program.