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Information on ZOPICLONE for Service Users and their Families This leaflet provides general information about your medication. Manufacturer patient information leaflets are also provided with all medicines. If you require further information, speak to your doctor, pharmacist or nurse. Zopiclone is also known as Zimovane®. It is available as: tablets called Zimovane ® tablets, Zimovane ® LS tablets or just zopiclone tablets Zopiclone is pronounced Zo - pee - clone Reviewed by: DTC On: January 2014 Next Review: January 2017 The Mersey Care Medicines Information Service1 regularly updates this information sheet. 1 Medicines Information, Pharmacy, Mossley Hill Hospital, Park Avenue, Liverpool L18 8BU What is Zopiclone for? Zopiclone is part of a group of medications called hypnotics (sleeping tablets) which are used to treat people with severe difficulty sleeping (insomnia) that is causing severe distress. Hypnotics may be helpful for people who have difficulty going to sleep, who sleep for short periods or who awaken very early or many times during the night. How should I take Zopiclone? Before taking zopiclone, tell your doctor if: you are allergic to zopiclone of any of its ingredients you suffer from any other conditions especially kidney or liver disease, breathing problems like severe sleep apnoea, a condition called myasthenia gravis (muscle weakness) or history of drug and alcohol misuse you take any other medication including any medicines or supplements or herbal remedies that you bought yourself you are pregnant (or planning pregnancy) or breastfeeding Your doctor will decide how much zopiclone is right for you to take. Zopiclone tablets are normally prescribed for short periods only. Others methods of dealing with insomnia should also be tried. Swallow your tablets whole, with a small glass of water, at bedtime. Never take more than the prescribed dose. If you accidentally take more than the prescribed dose or an overdose of zopiclone, contact your doctor or your local hospital. Ask your pharmacist or nurse if you are not sure of anything. Can I stop taking Zopiclone if I feel better? Zopiclone is usually used for a short time only, usually four weeks or less. However, it is best to discuss with your doctor how long you will need to be on this medication. If you want to stop zopiclone, it is better to do this in discussion with your doctor. You may have to stop slowly to prevent any unpleasant withdrawal effects. What if I forget a dose of Zopiclone? If you forget to take a dose of zopiclone, take your next dose at the usual time. Do not try to make up for the missed dose. Remember, if you take zopiclone too late at night you may feel more drowsy the next morning. When will Zopiclone start to work? Zopiclone should start to work about half an hour to an hour after you take them. Are there any side effects? Zopiclone can cause side effects in some people, but these may vary from person to person. Many side effects wear off over time. Known side effects include: bitter taste in the mouth forgetfulness feeling or being sick drowsiness dry mouth confusion nausea headache lightheadedness stomach problems dizziness feeling irritable or restless Some people can get tolerant to zopiclone and may feel that its benefits have reduced over time. If you feel you are beginning to depend on your medication, speak to your doctor. Occasionally, more serious side effects can occur. These include: allergic reaction: skin rash, swelling or difficulty breathing low mood, changes in behaviour numbness or tingling of hands and feet fast or uneven heartbeat coordination problems breathing difficulties nightmares, sleep walking or sleep driving loss of memory seeing or hearing things that are not real falls (mainly in older adults) If you suffer these or any other side effects, talk to your doctor, pharmacist or nurse. If you think a medicine has caused you an unwanted side effect, please report the problem either on a Yellow Card form available from your doctor, nurse or pharmacist OR online at this website http://yellowcard.mhra.gov.uk/. Can I take other medicines? Zopiclone may interact with other medicines causing unwanted side effects. Medicines you can buy over the counter without a prescription may interact with prescribed medicines. Always ask your doctor or pharmacist before taking any other medicines. Can I drive? Zopiclone can make you feel very sleepy, dizzy and less alert. You may also feel drowsy the next day. If you are affected in this way, do not drive or work with machinery. Can I drink alcohol? Avoid drinking alcohol while taking zopiclone. The combination of alcohol and zopiclone can make you feel more sleepy than usual and even affect your breathing. Can I get pregnant or breast feed? Medicines can have harmful effects at any time during pregnancy. If you are pregnant, or are planning to get pregnant, you should seek advice from your doctor. You and your doctor or specialist will decide if the potential benefits of treatment outweigh the potential risks to the baby. Zopiclone passes into breast milk. If you are breast feeding, you should get your doctor’s advice. What alternative treatments are there? Other medications that can be used for sleeping problems include zolpidem and benzodiazepines prescribed for short periods. Your doctor or pharmacist will be able to provide you with further information about these medications. Ways of treating insomnia that do not involve the use of medicines to help with sleep should always be tried first. IMPORTANT Remember to keep medicines where children cannot see or reach them. Never share medicines with others even if their symptoms appear the same as yours. NEVER EXCEED THE STATED DOSE OF YOUR MEDICINE