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AAPM E-NEWS Plan to attend next year's Annual Meeting in Washington DC, March 24-27, 2011 Pre-meeting activities begin Wednesday, March 23rd Pain Medicine, D.C. The Governing Voices of Pain: Medicine, Science, and Government September 27, 2010 - Your Latest News on the Specialty of Pain Medicine LATEST NEWS from the American Academy of Pain Medicine Pain Research in the News Pain Treatments/Trials in the News Substance Abuse & Addiction Research Practice Management & Coding Updates Join the Discussion AAPM Members in the News AAPM Annual Meeting • Scientific Abstract Submission Deadline is September 30, 2010 American Board of Pain Medicine (ABPM) Pain Resources Pain Abstracts in the News PubMed Pain Abstracts NIH Clinical Studies & Trials Pain Research in the News Most Report too Much Hospital Pain September 22, 2010 [Source: UPI.com] A study by German researchers surveyed over 3,000 hospital patients (2,250 surgical patients and nearly 1,000 non-surgical patients) and found that 56 percent of hospital patients indicated that their pain suffered in the hospital was unbearable. Fifty-five percent of the hospital patients also reported that their pain therapy in the hospital was unsatisfactory. The survey was part of the Pain-Free Hospital Project. Full story... View original article in Deutsches Aerzteblatt International... High-Dose Aspirin Reduces Pain for Severe Headache and Migraine September 21, 2010 [Source: University of California, San Francisco] Researchers at the University of California, San Francisco, found that high-dose intravenous aspirin was effective for the treatment of severe headache and migraine caused by drug withdrawal. Participants reported a significant reduction in pain 25 percent of the time. Full story... View related Cochrane Review... Risk Factors for ER Visits in Chronic Opioid Users Identified September 17, 2010 [Source: Modern Medicine] Seeking a Pain Specialist? A recent study in the Archives of Internal Medicine found that the use of Schedule II opioids, headache, back pain, and substance use disorders were all associated with emergency department visits and alcohol- or drug-related encounters (ADEs). The risk was doubled for ADEs when the daily opioid use was higher than 120 mg/d (morphine-equivalent). Full story... View abstract on Archives of Internal Medicine... Post your position in the AAPM Career Center and reach more than the 2,400 members of AAPM. The network reaches beyond 30,000 professionals in healthcare. AAPM Releases Pain Position Paper Plenary Proceedings of the 24th Annual Meeting Plenary Proceedings of the 24th Annual Meeting contains exciting, forward thinking perspectives currently driving the emerging field of Pain Medicine. Order your copy TODAY Price: $79 UC Davis Scientists Find Link Between Arthritis Pain Reliever and Cardiovascular Events September 13, 2010 [Source: UC Davis Health System] Researchers from the University of California, Davis and Peking University in China, used metabolomic profiling to analyze murine (rodent) plasma to discover that Vioxx caused a dramatic increase in regulatory lipid that could be a major contributor to heart attacks and strokes associated with high-levels of the drug and other selective COX-2 inhibitors. Scientists hope this discovery will lead to the development of safer drugs for those suffering with acute or chronic pain. Full story... View a review at NIH Public Access (Mol. Cell Pharmacol.)... Scripps Research Scientists Identify Molecules Involved in Touch and Other Mechanically Activated Systems September 2, 2010 [Source: The Scripps Research Institute] Researchers at Scripps Research Institute identified two proteins, Piezo1 and Piezo2, which are involved in cellular response to mechanical stimulation. Scientists believe that these proteins may be important targets for research in pain, deafness, and cardiac and kidney dysfunction. Full story... View original abstract at Science... Back to top Pain Treatments/Trials in the News Fuisz Announces Further Advances in Drug Compliance Verification for Opioids September 21, 2010 [Source: PR Newswire] Fuisz Pharma introduces its Closed Loop Diagnostic System that will help physicians identify compliant and non-compliant patients' use of opioids. Full story... Potential First-in-Class Compound, Reveals New Approach to the Treatment of Pain (D3) September 20, 2010 [Source: Business Wire] 4 easy ways to order: Phone: 847-375-4731 Fax: 847-375-6477 Email: [email protected] Mail: AAPM P.O. Box 839 Glenview, IL 60025-0839 ORDER FORM Researchers at the Italian Institute of Technology and the University of California, Irvine, presented results from a preclinical study that show the potential drug URB937, a potent, second-generation inhibitor of the enzyme fatty acid amide hydrolase, controlled pain and inflammation locally at the site. The drug boosted levels of anandamide in peripheral tissues. Full story... View at original article at Nature Neuroscience... EuroPharma Release: BCM-95 Demonstrates Superior AntiInflammatory Effects, Baylor University Medical Center Study September 16,2010 [Source: ClinicaSpace] Researchers at Baylor University Medical Center found that BCM-95, a new patented extract of curcumin, was absorbed up to 10 times better than conventional curcumin, possessing potent anti-inflammatory properties. Full story... View related article at NIH Public Access (Curr Aging Sci.)... Arcion Therapeutics Receives FDA Fast Track Designation for ARC-4558 for the Treatment of Pain Associated with Painful Diabetic Neuropathy September 14, 2010 [Source: BioSpace] PATIENT INFORMATION Arcion Therapeutics’s ARC-4558, a 0.1% gel formulation of clonidine hydrochloride for topical administration for treatment of painful diabetic neuropathy, has been placed in the Fast Track program of the FDA and is now set to enter Phase 3 studies. Full story... Diamyd Medial Issues Positive Phase I Data for Chronic Pain Patient Education Videos Now Available Online Online videos are now available in the Patient Portal section of the AAPM website for your patients to view: View "Finding Relief: Pain Management for Older Adults" video View "Managing Chronic Pain, A Guide for Patients" video Educational Booklet and DVD Copies of the new educational booklet and DVD, Finding Relief: Pain Management for Older Adults are available to members free of charge, with the addition of a modest shipping fee. To request copies of this resource email: [email protected]. UPDATES The AAPM Power Point Presentation on the Federal Regulations for Prescribing has been updated as of 6/01/2010. View this new presentation. Revised AAPM Ethics Charter Includes statement on conflicts of interest. Therapy September 13, 2010 [Source: Trading Markets] Diamyd Medical will begin Phase II clinical trial of its NP2 as a potential therapy for chronic pain. This is the first drug candidate using Diamyd’s proprietary Nerve Targeting Drug Delivery System platform, which focuses on delivery of therapeutic compounds directly to the nervous system. Full story... Back to top Substance Abuse & Addiction Research National Survey Reveals Increases in Substance Use from 2008 to 2009 September 16, 2010 [Source: SAMHSA] A National Survey on Drug Use and Health (NSDUH) by SAMHSA found that the overall rate of current illicit drug use in the U.S. increased from 8.0 percent of the population aged 12 and older in 2008 to 8.7 percent in 2009 and was largely due to increased marijuana use. The study also found that the nonmedical use of prescription drugs rose from 2.5 percent in 2008 to 2.8 percent in 2009 among the population. Full story... View complete survey at SAMHSA... Substance Abuse Admissions Double Among Older Adults September 9, 2010 [Source: Medline Plus] The National Survey on Drug Use and Health also reported that the number of people aged 50 and older admitted for substance abuse treatment rose from 102,700 in 1992 to 231,200 in 2008, with 65.8 percent of the admissions among Caucasians. Full story... Back to top Practice Management & Coding Updates CODING & REIMBURSEMENT UPDATES New ICD-9-CM Codes Effective October 1, 2010 Emily Hill, PA Need Facts on Pain? Updated: Visit AAPM's "Facts on Pain" section in the Patient Center of the AAPM website, which now includes detailed references to each fact. These are helpful to have on hand for media calls. Read more... Affiliate Membership Are the members of your pain team AAPM members? ICD-9-CM changes have been released and become effective October 1, 2010. A complete list of all ICD-9-CM changes can be found in the front of most editions of the manual. The number of annual changes is expected to be minimal over the next several years as we move to ICD-10 on October 1, 2013. Read more... PRACTICE MANAGEMENT The Practice Management section of the AAPM website offers practical tools and resources for you to use in your pain practice, as well as coding updates, reimbursement news, and other information that impacts your practice. Visit this helpful section on the website Back to top Join the Discussion Latest Topic in the AAPM Members' Discussion Forum An AAPM member from Teaneck, New Jersey, asked the question, "Does anyone have experience prescribing Marinol for pain? Despite its schedule 3 Affiliate membership information... The American Board of Pain Medicine (ABPM) is committed to the certification of qualified physicians in the field of Pain Medicine. Visit abpm.org to view ABPM's mission, vision, and objectives. Pain Medicine: September, 2010 Highlights: EDITORIAL Gender Differences in the Affective Processing of Pain: Brain Neuroscience and Training in "Biopsychosocial" Pain Medicine SPINE SECTION Efficacy of Fluoroscopically Guided, Contrast-Enhanced Lumbosacral Interlaminar Epidural Steroid Injections: A Pilot Study PALLIATIVE CARE SECTION Factors Associated with Clinician Intention to Address Diverse Aspects of Pain in Seriously Ill Outpatients PSYCHOLOGY, PSYCHIATRY & BRAIN NEUROSCIENCE Differences in Pain, Psychological Symptoms, and Gender Distribution among Patients with Left- vs RightSided Chronic Spinal Pain ACUTE PAIN SECTION Continuous Transversus Abdominis Plane (TAP) Block Catheters in a Combat Surgical Environment View all topics slated for the next issue of Pain Medicine Journal or go to the Library section of the AAPM website for more information. MEMBERSHIP AAPM Membership Renewals Membership renewals are currently being sent out. Don't miss the opportunity to continue being a part of the primary organization for physicians practicing in the specialty of pain medicine. As a member you will continue to receive the AAPM ENews, Pain Medicine, the official journal of AAPM, as well as representation and advocacy in Washington DC, up-to-date coding information, discounts on AAPM's Annual Meeting, and a host of other status there are obvious stigmas attached. Is there increased risk of DEA scrutiny with occasional prescriptions? With frequent prescriptions?" Visit the Discussion Forum to post your comments (login required) Back to top AAPM Members in the News Small Study Suggests Electrical Stimulation of the Brain Can Ease Migraine Pain September 18, 2010 [Source: Los Angeles Times] AAPM member, Joel Saper MD, is featured in a Los Angeles Times article discussing a small pilot study on the use of electrical stimulation on the occipital nerve to treat chronic migraine. Full story... Washington Legislation Targets Opioid Abuse, But at What Cost? September 2010 [Source: Pain Medicine News] AAPM President, Eduardo Fraifeld MD, and AAPM Co-Chair of the Research Committee, Alex Cahana MD, discuss the impact of the new Washington State legislation, which introduces “measurement-based care” in the field of pain management. Full story...(login required) A Different Kind of Pain September 9, 2010 [Source: msnbc.com] Dr. Alex Cahana discusses phantom pain in an interview featured online on Nightly News with Brian Williams. View video... Back to top AAPM Annual Meeting AAPMedicine's 2011 Call for Scientific Poster Abstracts: DEADLINE: September 30, 2010 The 2011 Program Committee invites you to submit proposals for scientific abstracts to be presented at the AAPM 27th Annual Meeting, March 24-27, 2011, at the Gaylord National Hotel and Convention Center in National Harbor, MD. 2011 - Poster Award The 2011 Scientific Poster Abstract Committee will select up to 5 scientific poster abstract submitters to present their research during a "live" Plenary Research Highlights session held Saturday morning during the 2011 Annual Meeting. This honor includes the recognition of "Faculty" status at the meeting. As faculty of the annual meeting, the presenters' airfare, lodging and Annual Meeting registration are complementary (up to a dollar amount that will be specified at a later date.) If there are questions regarding this amount, please email [email protected]. As an additional reward, each of these presenters will also receive complementary meeting registration for the 2012 AAPM Annual Meeting in Palm Springs, California. member benefits. Pay dues online or for phone assistance, please call customer service at 847/375-4731. Bring in a new, paid, active AAPM member and receive the Plenary Proceedings of the 24th Annual Meeting, which contains exciting, forward thinking perspectives currently driving the emerging field of Pain Medicine. A $79 value. Contact [email protected] to receive your thank you for referring a new AAPM. With membership at an unprecedented level, more than 2,400 physicians and their pain teams are part of this premier medical specialty society, practicing in pain medicine from origins in anesthesiology, neurosurgery, neurology, physiatry, and psychiatry. For more than 25 years, the American Academy of Pain Medicine (AAPM) has provided education, training, advocacy and research in the specialty of pain medicine. Consider joining AAPM today and become part of this growing medical specialty society. Visit www.painmed.org for more information. AAPM on Social Networking Sites Join the AAPM Linked-In Group and become a "fan" of AAPM on Facebook Hurry! AAPM’s Scientific Abstract Submission Deadline is September 30th! Click Here for complete details. For more information, or to apply online, visit: www.painmed.org or call Mary O’Keefe 847-375-4809. Back to top American Board of Pain Medicine (ABPM) ABPM Now Accepting 2011 Examination Applications Deadline: October 1, 2010 There is still time to apply for the American Board of Pain Medicine (ABPM) 2011 certification and recertification examinations. The final filing postmark deadline for both examinations is Friday, October 1, 2010. Both examinations are available in an electronic format, eliminating the need to travel to one location to take a paper and pencil exam. Online testing is offered through ACT testing sites nationwide during the 3-week window of Saturday, April 2, 2011 through Saturday, April 23, 2011. For information on ACT test center locations, visit http://www.act.org/actcenters/locate/index.html. If you are interested in certifying with ABPM, or if you are a Diplomate who needs to recertify, please visit www.abpm.org to download the applicable examination materials, or contact the ABPM office to request a copy of the Examination packet at (847) 375-4726 or [email protected]. Back to top Pain Resources American Pain Foundation Launches PainSAFE™ The American Pain Foundation (APF) launched PainSAFE™ (Pain Safety & Access For Everyone), a new educational initiative designed for people with pain and health care professionals. AAPM treasurer, Lynn Webster MD, initiated the project for the National Pain Foundation (NPF), which was then moved forward and completed after NPF's assets were integrated into the American Pain Foundation this past May. Visit PainSafe™ Back to top Pain Abstracts in the News Botulinum Toxin for Shoulder Pain September 8, 2010 [Source: Cochrane Reviews] Abstract: Background: Recent evidence suggests an anti-nociceptive effect of botulinum toxin. Objectives: To compare the efficacy and safety of botulinum toxin in comparison to placebo or other treatment options for shoulder pain. Read more... View Intervention Review at The Cochrane Library... Golimumab Eases Sleep in Ankylosing Spondylitis September 2010 [Source: Arthritis Care & Research] Abstract: Objective: To evaluate the effect of golimumab on sleep disturbance in patients with active ankylosing spondylitis (AS). Read more... View drug review at the journal of Core Evidence... Identification, Treatment, and Clinical Outcomes of Neuropathic Pain for the Primary Care Physician August 2010 [Source: Journal of Clinical Outcomes Management] Abstract: Objective: To provide an overview of and roadmap to using the options available for the appropriate diagnosis and treatment of neuropathic pain. Read more... Back to top PubMed Pain Abstracts The following abstracts are posted at PubMed.gov Post-Traumatic Stress Disorder, Drug Abuse and Migraine: New Findings from the National Comorbidity Survey Replication (NCSR) Cephalalgia. 2010 Sep 2. [Epub ahead of print] Peterlin BL, Rosso AL, Sheftell FD, Libon DJ, Mossey JM, Merikangas KR., Johns Hopkins University, USA. Abstract: Background: Post-traumatic stress disorder (PTSD) has been shown to be associated with migraine and drug abuse. Methods: This was an analysis of data from the National Comorbidity Survey Replication (NCS-R) to evaluate the association of PTSD in those with episodic migraine (EM) and chronic daily headache (CDH). PMID: 20813779 [PubMed - as supplied by publisher] Read more... View related article at Pediatrics... Milnacipran for Treatment of Fibromyalgia Ann Pharmacother. 2010 Sep;44(9):1422-9. Epub 2010 Aug 17. Kyle JA, Dugan BD, Testerman KK. Samford University, Birmingham, AL, USA. Abstract: OBJECTIVE: To review the pharmacology, pharmacokinetics, efficacy, and safety of milnacipran and evaluate relevant clinical trial data. PMID: 20716692 [PubMed - in process] Read more... View abstract at The Annals of Pharmacotherapy... View related article at Arthritis & Rheumatism... Clinical Characteristics of Veterans Prescribed High Doses of Opioid Medications for Chronic Non-Cancer Pain Pain. 2010 Aug 27. [Epub ahead of print] Morasco BJ, Duckart JP, Carr TP, Deyo RA, Dobscha SK. Mental Health and Clinical Neurosciences Division, Portland VA Medical Center, Department of Psychiatry, Oregon Health & Science University, USA. Abstract: Little is known about patients prescribed high doses of opioids to treat chronic non-cancer pain, though these patients may be at higher risk for medication-related complications. We describe the prevalence of high-dose opioid use and associated demographic and clinical characteristics among veterans treated in a VA regional healthcare network. PMID: 20801580 [PubMed - as supplied by publisher] Read more... A Multicenter, Placebo-Controlled, Double-Blind, MultipleCrossover Study of Fentanyl Pectin Nasal Spray (FPNS) in the Treatment of Breakthrough Cancer Pain Pain. 2010 Aug 25. [Epub ahead of print] Portenoy RK, Burton AW, Gabrail N, Taylor D; on behalf of the Fentanyl Pectin Nasal Spray 043 Study Group. Beth Israel Medical Center, New York, NY, USA. Abstract: This randomized, double-blind, crossover study assessed the efficacy and tolerability of a new rapid onset nasal fentanyl formulation (Fentanyl Pectin Nasal Spray; FPNS) for breakthrough cancer pain (BTCP). Eighty-three of 114 patients experiencing one to four BTCP episodes/day while taking 60mg/day of oral morphine or equivalent successfully identified an effective dose of FPNS during a titration phase and entered a double-blind phase in which 10 BTCP episodes were treated with this effective dose (7) or placebo (3). Compared with placebo, FPNS significantly improved mean summed pain intensity difference (SPID) from 10min (P<0.05) until 60min (P<0.0001), including the primary endpoint at 30min (P<0.0001). PMID: 20800358 [PubMed - as supplied by publisher] Read more... Pharmacologic Management of Chronic Pain Korean J Pain. 2010 Jun;23(2):99-108. Epub 2010 May 31. Park HJ, Moon DE. Department of Anesthesiology and Pain Medicine, School of Medicine, The Catholic University of Korea, Seoul, Korea. Abstract: Chronic pain is a multifactorial condition with both physical and psychological symptoms, and it affects around 20% of the population in the developed world. In spite of outstanding advances in pain management over the past decades, chronic pain remains a significant problem. This article provides a mechanism- and evidence-based approach to improve the outcome for pharmacologic management of chronic pain. PMID: 20556211 [PubMed - in process] Read more... PMCID: PMC2886242 Free article available on PubMed Central... Back to top NIH Clinical Studies & Trials The following studies and trials are posted at ClinicalTrials.gov Methadone in Neuropathic Pain This study is not yet open for participant recruitment. First Received: September 17, 2010 Sponsor: Capital District Health Authority, Canada Collaborators: Canadian Institutes of Health Research (CIHR), Nova Scotia Health Research Foundation, Dalhousie University Information provided by: Capital District Health Authority, Canada ClinicalTrials.gov Identifier: NCT01205516 Stated Purpose: There is an important need for inexpensive drugs that treat neuropathic pain. Early research suggests that methadone may be a good, inexpensive drug to treat neuropathic pain. Methadone is available in a low cost powder that is easily prepared for different routes of administration. This study will look at the effect and safety of methadone compared to the regular treatment of morphine for the treatment of chronic neuropathic pain. Read more... IRB-HSR# 13957: IV Lidocaine for Patients Undergoing Primary Breast Cancer Surgery: Effects on Postoperative Recovery and Cancer Recurrence This study is enrolling participants by invitation only. First Received: September 15, 2010 Last Updated: September 16, 2010 Sponsor: University of Virginia Principal Investigator: Mohammed Tiouririne, MD, UVA Dept of Anesthesiology Information provided by: University of Virginia ClinicalTrials.gov Identifier: NCT01204242 Stated Purpose: The purpose of this study is to determine whether a local anesthetic drug (lidocaine) given during anesthesia intravenously (IV) through a needle in your vein,), can, 1.) Help decrease pain after surgery, 2.) Have you need less pain medication, 3.) Have less side effects like nausea and vomiting following your surgery. 4.) Help to prevent chronic pain, and 5.) Affect recurrence of cancer after surgery. Read more... Read related article at Revista Brasileira de Anestesiologia (Scroll down for English Version)... A Study to Investigate the Analgesic Efficacy of AZD2423 Compared With Placebo After 28 Days Treatment in Patients With Painful Diabetic Polyneuropathy This study is not yet open for participant recruitment. First Received: September 13, 2010 Sponsor: AstraZeneca Study Director: Bror Jonzon, AstraZeneca R&D Södertälje Information provided by: AstraZeneca ClinicalTrials.gov Identifier: NCT01201317 Stated Purpose: A study to investigate the analgesic efficacy of AZD2423 compared with placebo after 28 days treatment in patients with painful diabetic polyneuropathy. Read more... A Rheumatoid Arthritis Study in Patients on a Background Treatment of Methotrexate This study is not yet open for participant recruitment. First Received: September 8, 2010 Sponsor: Eli Lilly and Company Information provided by: Eli Lilly and Company ClinicalTrials.gov Identifier: NCT01198002 Stated Purpose: The primary purpose of this study is to help answer if LY2127399 is safe and effective in the treatment of rheumatoid arthritis while on a background treatment of methotrexate. Read more... OXN PR vs Placebo in Opioid-naive Subjects Suffering From Severe Pain Due to Bladder Pain Syndrome (BPS) This study is not yet open for participant recruitment. First Received: September 7, 2010 Last Updated: September 8, 2010 Sponsor: Mundipharma Research GmbH & Co KG Information provided by: Mundipharma Research GmbH & Co KG ClinicalTrials.gov Identifier: NCT01197261 Stated Purpose: The study compares the analgesic efficacy of OXN PR vs placebo in opioid-naive subjects suffering from severe pain due to Bladder Pain Syndrome. Read more... View related article at NIH Public Access at J Urol... View related article at NIH Public Access at Neurourol Urodyn... View related article at Reviews in Obstetrics & Gynecology... Back to top Click here to unsubscribe. American Academy of Pain Medicine 8735 W. Higgins Road, Suite 300, Chicago, IL 60631 847/375-4731 847/375-6477 Fax [email protected] www.painmed.org