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Parathyroid
Hormone
Forteo
(Teriparatide)
Reclast OR Zometa
(Zolendronic Acid) Bisphosphonate
Calcitonin
Bisphosphonate
Aredia
(Pamidronate)
Miacalcin
Bisphosphonate
Boniva
(Ibandronate)
SERM
Spine & Hip
Cortical (surface) Bone
Bisphosphonate
Actonel
(Risedronate)
Evista
(Raloxifene)
Spine & Hip
Cortical (surface) Bone
Bisphosphonate
Fosamax
(Alendronate)
Spine & Non-vertebral Sites in
Cortical & Trabecular
(inner/structural) Bone
Spine
Cortical (surface) Bone
Mostly Spine
Cortical (surface) Bone
Spine
Cortical (surface) Bone
Spine & Hip
Cortical (surface) Bone
Spine & Hip
Cortical (surface) Bone
Type of Drug
Drug
Type of Bone Showing
Increase of BMD/Reduction
of Fracture Risk
■
Increases Osteoblast
(Bone Building Cells)
■
■
■
■
■
■
■
Suppresses Osteoclast
(Bone Break Down)
Available in weekly dose or
once a month
Available in weekly dose,
Liquid form or w/ Vitamin D
Misc. Info.
Reclast / Zometa--IV Infusion
1 time per year. Must take
calcium and Vitamin D
following infusions
Reclast Approved / Zometa Not
FDA Approved for Treatment Of
Osteoporosis
Daily Subcutaneous injection,
2 year limit
Nasal spray, must be kept
refrigerated
S/Forms/DEXA/Comparing bone Strengtheners.xls
Revised 01-01-2008
Page 1 of 1
High Risk Men and Women
Treatment for Post-Menopausal
Women Only
Treatment for Post-Menopausal Sometimes confused w/ HRT,
Women Only
yet is NON-Hormonal
IV Infusion 1 time every 3
months
Not FDA Approved for Treatment
Of Osteoporosis
Prevention & Treatment in Men Available in monthly dose or IV
and Women
Push every 3 mo.
Prevention & Treatment in Men
and Women
Prevention & Treatment in Men
and Women
Approved For
Comparing Brand-Name Bone Strengtheners
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