Download One heartbeat at a time.

2010
| Annual
Report
One heartbeat at a time.
It is time.
Time matters. Time with our loved ones. Time to accomplish the work and relish the joys of the
world. Time truly matters when you are having a heart attack…when your child is living with
cardiovascular disease…when someone you love is waiting for a heart transplant.
Time matters because risk factors for heart disease — obesity and diabetes — are rising swiftly in
the United States and globally. Time matters because heart disease is now
the number one cause of death around the world.
The Minneapolis Heart Institute Foundation is committed to stopping this disease,
and we are making significant progress. Through innovative education programs and
groundbreaking research, we are discovering how to prevent and treat heart
disease at ever-earlier stages.
Established in 1982 by a group of Minneapolis Heart Institute® physicians, we
have a vitally important mission: To promote and improve cardiovascular
health, quality of life and longevity for all.
The community supports this mission through philanthropic
giving. We are indebted to all of you and we look forward to
sharing our achievements with you as we move forward
in new directions.
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One heartbeat at a time.
The Minneapolis Heart Institute
Foundation’s mission is to promote and
improve cardiovascular health, quality
of life and longevity for all.
Creating a world without heart disease®
S c i e n t i f i c I n n o vat i o n & R e s e a r c h
The Minneapolis Heart Institute Foundation is one of the nation’s top ten centers for
cardiovascular research and education. Publishing more than 120 peer-reviewed studies
annually, MHIF is a recognized research leader in the broadest range of cardiovascular
medicine including: hypertrophic cardiomyopathy, adult stem cell therapy, acute myocardial
infarction, electrophysiology, heart failure, imaging, peripheral artery disease and prevention.
Each year, cardiologists and hospitals around the
world adopt MHIF protocols to save lives and
improve patient care.
E d u c at i o n & O u t r e a c h
Research shows that modifying specific health behaviors can significantly reduce
the risk of developing heart disease. Through our community programs, screenings
and presentations, we educate people of all walks of life about heart health.
The goal of our community outreach is to increase
personal awareness of risk factors and provide the tools
necessary to help people pursue heart-healthy lifestyles.
Time to reflect.
In 2010, MHIF made headlines with its significant outcomes in cardiovascular research and
education. Our work is consistently featured in highly respected journals and media outlets
including the Journal of the American Medical Association, Circulation, the New York Times,
Wall Street Journal, and the New England Journal of Medicine. A quick glance at some of
the headlines…
A dvan cin g A d u lt S t e m C e l l T he r apy
Making Advances
in Adult Stem
Cell Therapy
MHIF researcher Jay H. Traverse, MD, published a study
in the September issue of the American Heart Journal
demonstrating that adult bone-marrow stem cells are safe
in treating acute myocardial infarction (heart attack).
MHIF is a member of the National Institutes of Healthfunded Cardiovascular Cell Therapy Research Network. This
consortium of five centers across the United States is dedicated
to studying stem cell therapy in the treatment of heart disease.
MHIF is treating the largest number of heart patients
using adult stem cell therapy in the United States.
Tackling the Leading Killer of Women
HEALTH NEWS
Tackling the Leading Killer of Women
Science Review
Kim’s Story
Atrial Fibrillation in Infants
MHIF co-hosted a two-day summit for medical professionals
and thought leaders in April 2010 entitled Women and Heart
Disease: A Summit to Eliminate Untimely Deaths in Women.
The conference highlighted and explored gender disparities
in heart attack symptoms, diagnosis and treatment, and
examined efforts to raise community awareness of women’s
risk for heart disease.
Given her young age and healthy lifestyle, Kim never thought she would have a heart attack.
Read Kim’s story at mplsheart.org/2010annualreport.
I m p rov in g Tr e at m e n t fo r
Irr e g u l ar H e art be ats
Atrial fibrillation is a heart rhythm problem often treated
with ablation, a procedure that interrupts abnormal electrical
pathways in the heart muscle. Ablation is an effective treatment
for the disorder, but can cause post-treatment pain. Preliminary
results from an MHIF pilot study by Daniel Melby, MD,
show that using a steroid after ablation can reduce pain and
may even keep atrial fibrillation from recurring.
Pr ev e n t in g H e art At tack s
B e fo r e T hey O ccu r
MHIF conducted one of the first studies to
look at patients before they have a heart attack.
The study, led by Kevin J. Graham, MD, demonstrates that
most first-time heart attacks can be prevented. Evidence from
this study suggests that high-risk patients often disregard medical
advice and are not identified and treated for the early onset of
their disease. These findings should help in earlier identification
of these patients, decreasing their risk of heart attack.
Br e ak in g T hro u g h
B lo ck e d Art e r ie s
An MHIF trial led by M. Nicholas Burke, MD, is looking at a
novel approach to opening totally blocked arteries — the most
challenging to treat. The study demonstrates the safety and
effectiveness of a new system to prepare a blocked artery for
angioplasty, which opens the artery with an inflated balloon,
and for placement of a stent, which keeps the artery open.
Saving lives and improving health.
With every heartbeat.
The Minneapolis Heart Institute Foundation follows your heart and the hearts of
those you love through every life stage. We educate your children and grandchildren
on heart-healthy lifestyle choices. We are here for you with the most innovative therapies
when you or a loved one has a heart attack. And we provide options to improve your
quality of life even when your heart is failing.
Following Your Heart Through Every Life Stage
Pre-Birth
Birth
Childhood
Genetic Arrhythmia
Hypertrophic Cardiomyopathy (HCM)
Imaging
Girls and Moms on the Move
A n sw e rs f o r a n I n h e r i t e d H e a rt D i s e a s e
Pre-Birth
Late Adulthood
Led by William T. Katsiyiannis, MD, MHIF established the Genetic Arrhythmia Center in 2008.
It serves patients and families affected by rare genetic arrhythmias – altered heart rhythms and
heart rates that carry serious health risks, including cardiac arrest and death. The center gives hope
to families asking, “Who’s next?”. Through genetic testing and counseling, family members are
given access to the latest treatment, diagnosis and monitoring options.
Dostal’s Story
The Genetic Arrhythmia Center has given hope to countless families. Read the Dostal family’s story
at mplsheart.org/2010annualreport.
H e a lt h y C o n n e c t i o n s : G i r l s a n d M o m s o n t h e M o v e
Childhood
The preteen years are tough on young girls. Societal pressures along with emotional and physical
changes make it especially important to encourage healthy behaviors. Girls and Moms on the
Move is a six-week program designed to do just that. The program gives mothers and daughters
(aged 8-12 years) the opportunity to get healthy, be active and have fun together. It combines
educational presentations and experiences with group physical activity sessions and culminates
in a 5K walk or run. Piloted in 2009, workshops were offered this year in communities throughout
the Twin Cities, outstate Minnesota and Iowa.
Early
Adulthood
Middle-Age
Lead Safety
The Heart of New Ulm Project
Women on the Move
OPTIMIST Program
Vascular/Endovascular Therapies
Heart Attack Treatment
Systems of Care
Late
Adulthood
Heart Failure Therapies
Valvular Heart Therapies
c lo s i n g i n o n t h e n u m b e r o n e c au s e o f
s u d d e n d e at h i n y o u n g p e o p l e
Pre-Birth
Late Adulthood
Hypertrophic cardiomyopathy (HCM) is a thickening of the heart muscle that inhibits the
outflow of blood. HCM affects approximately one in 500 people. Thanks to the pioneering work
of Barry J. Maron, MD, director of the MHIF Hypertrophic Cardiomyopathy Center, HCM is
now a treatable condition that can be managed with drugs, implantable defibrillators, pacemakers,
surgery and ablation, as well as genetic counseling. Dr. Maron has published more than 800
articles on this condition (31 in 2010 alone) in prestigious journals such as Circulation, the
New England Journal of Medicine and the Journal of the American Medical Association.
Hearts B e at B ac k : The Heart of New Ulm Project
Early Adulthood
Late Adulthood
2011 marks the third year of MHIF’s ambitious pilot program that continues to receive national
attention for its innovative strategies to reduce heart attacks in an entire town. Partnering with
Allina Hospitals & Clinics, New Ulm Medical Center and the entire city of New Ulm, we teach
heart-healthy behaviors that improve nutrition, increase exercise and stop tobacco use.
• In 2010, we launched our first Community Health Challenge, dividing the city into
districts and recruiting volunteer health leaders in each neighborhood. The result has
been a surge in activity levels, with districts hosting dance events, walking clubs and more.
• We also launched the HeartBeat Connections program that targets the 1,500 people
at highest risk for a heart attack. The program provides aggressive medical intervention
to manage blood pressure and cholesterol levels.
In 2011, our focus is on reducing New Ulm’s 73% obesity
rate, with the Take Five Challenge that promotes five easy
actions community members can take to reduce or
maintain weight.
94% of New Ulm community adults say they believe that
the Heart of New Ulm Project will be successful in its
mission to reduce heart attacks.
Taking the “Lead” on Patient Safety: Electrophysiology
Early Adulthood
Late Adulthood
MHIF researcher Robert G. Hauser, MD, is a strong advocate for patient safety. In 2010,
Dr. Hauser published a study looking at the safety of two common leads, which are the electrodes
in implanted cardioverter defibrillators (ICDs) that correct faulty heart rhythms. His highly
publicized work is helping physicians across the country make tough decisions for patients
with these leads.
Sav i ng H e a rt M us c le : I n n ovat iv e H e art At tack Tr e at m e n t
Middle Age
Late Adulthood
Research demonstrates that the rapid return of blood to the heart after opening a clogged artery
may cause damage to heart muscle. In a study funded by the National Institutes of Health, MHIF
researcher Jay H. Traverse, MD, is testing a technique called postconditioning which slows down
this rapid flow. This therapy has great potential to lessen the damage to the heart, reducing
a patient’s risk of heart failure.
I m a g i n g : A dva n c i n g t h e S c i e n c e o f C a r d i o va s c u l a r
Disease Diagnosis
Pre-Birth
Late Adulthood
MHIF houses the world’s largest database of MRI-CT images. These images help physicians
define and understand different types of vessel blockages, among many other applications,
and are instrumental in guiding patient care. MHIF researcher and Director of Education
Robert S. Schwartz, MD, is using imaging to study the effects of marathon running on
men’s and women’s coronary arteries.
210 Miles
100 Miles
50 Miles
Sy ste m s o f C a r e : Acc e l e r at in g
Tr e atm e nt, S avi ng L i ve s
Middle Age
Late Adulthood
MHIF develops protocols that significantly accelerate and improve emergency care.
These include:
Sarah’s Story
• Level 1– Patients with certain types of heart attacks are much more likely to recover if treated with
angioplasty within 90 minutes. This procedure is easily accessible in a large metro area hospital, but not in
outlying rural areas. MHIF’s Level 1 program, developed by MHIF Director of Research Timothy D.
Henry, MD, creates a standardized system that quickly and efficiently moves the patient from their local
hospital to a Level 1 hospital for fast intervention. The result: people who live within a 210-mile radius
of a Level 1 catheterization lab can now experience the same care as those who live right next door.
• Cool It – Quickly cooling body temperature through therapeutic hypothermia can help reduce the risk
of neurological damage in cardiac arrest patients. MHIF researchers led by Michael R. Mooney, MD,
have developed the Cool It protocol which ensures that this therapy happens immediately when a patient
presents with cardiac arrest. In 2010, MHIF hosted the conference, Miracle on Ice, to educate medical
professionals and to advocate for the use of the therapy in hospitals across the country.
Sarah feels blessed to live in a community where advanced therapies like Cool It are available.
Read her story at mplsheart.org/2010annualreport.
• Aortic Dissection – Aortic dissection, a tear in the inner lining of the aorta, is a rare but deadly medical
emergency. Accelerating the time between the patient’s arrival in the hospital and intervention is critical
because every second counts. An MHIF study led by Kevin M. Harris, MD, resulted in a 43% reduction
in the time from diagnosis to intervention, which potentially will save countless lives. MHIF
researcher Timothy M. Sullivan, MD, is also looking at less invasive methods for treating another
potentially dangerous condition called an abdominal aortic aneurysm. These new techniques can
greatly reduce the risk of more invasive surgery.
OPTION S FOR A FAILING HEA RT:
ADVANCED HEA RT FAILUR E THE R APIE S
Late Adulthood
More than 3,100 patients are on the heart transplant list. Of these, only 2,200 will receive hearts.
To help those patients waiting for a transplant, MHIF is researching mechanical pumps called left
ventricular assist devices (LVADs) that improve the heart’s own pumping function. Current research
led by David S. Feldman, MD, PhD, and Benjamin Sun, MD, is also looking at the potential for
making LVADs a long term option for patients who are not eligible for a heart transplant.
Marrel’s Story
An LVAD greatly improved Marrel’s quality of life as he waited for a heart transplant.
Read his story at mplsheart.org/2010annualreport.
VALVE CLINIC : R E S TO R ING HOPE , IMP ROVING Q UALITY OF LIFE
Late Adulthood
MHIF is at the forefront of innovative therapies for complex valve disorders. Under the leadership
of MHIF researcher Wesley R. Pedersen, MD, a team of caregivers has created the Valve Clinic
to provide an integrated approach to patient care and research. We are currently involved in a
pioneering study that could greatly improve the outlook for older, less healthy patients who are
not good candidates for open heart surgery.
Financial Highlights
Au d i t e d S u m m a r y o f R e v e n u e & E x p e n s e s 2 0 1 0
Revenues
Operations
Time or Purpose
Restricted Funds
Endowments
Contributions, 40%
Sponsorships, and Grants
$4,308,348
$681,086
$41,177
$3,408,338
-
-
2,512
$ 1,762,830
Research Study Revenues 31%
Investments/Trusts Change in Value
Licensing Fees
0%
$
6,990
7%
$
746,280
-
-
Income from Services
2%
$213,600
-
-
Payout from Endowments
5%
$
545,565
-
$ (545,565)
$1,618,112
$ (1,618,112)
-
Release of Time and 15%
Purpose Restricted Funds
Sources of Revenue
$10,847,233
$
$
(934,514)
$
1,258,442
Expenses
Program Services
$ ,2,220,541
Education
22%
-
-
$ 5,969,898
Research
60%
-
-
-
-
$ 930,738
Fundraising
9%
-
-
866,610
-
-
Total Supporting
$ 1,797,348
-
-
Board Designated Fund
$ (450,000)
$ 450,000
-
Total Program
$ 8,190,439
Supporting Services
Administration9%
Change in Net Assets
$
$
409,446
$
(484,514)
$
1,258,442
Au d i t e d b a l a n c e s h e e t, d e c e m b e r 3 1 , 2 0 1 0
Assets
Liabilities
Net Assets
Cash & Equivalents
$ 3,719,770
Accounts Payable
$
444,290
Unrestricted
$ 1,661,876
Investments
$ 16,776,860
Accrued Payroll
$
431,380
$ 3,485,914
Contributions Receivable $
Accrued Pension $
351,120
Unrestricted - Board
Designated Endowment
Pledges Receivable
$ 1,365,158
Other Accrued Expenses
$
390,060
Temporarily Restricted $ 3,938,615
Other Receivables
$ 1,304,860
Annuity Payment Liability
$
157,370
Restricted
$ 12,495,284
Other Assets
$
23,396
Accrued Rent
$
198,810
Total Net Assets
$ 21,581,689
Fixed Assets (net)
$
401,265
Deferred Revenue
$
102,650
TOTAL ASSETS
$23,657, 369
TOTAL LIABILITIES
$2,075,680
TOTAL LIABILITIES & NET ASSETS
$23,657, 369
66,060
Board of Directors
Phil Ankeny
Ann Bentdahl, Vice Chair
Forrest Burke
M. Nicholas Burke, MD, Chair
Barbara Burwell
Bradley Chapin
Deborah Dixson
Barbara Spell Dovolis
Marna Fullerton
Tamarra Giertz, Secretary
Morris Goodwin, Jr
Kevin J. Graham, MD
Elizabeth Z. Grey, MD
Robert G. Hauser, MD
Morrison Hodges, MD
Benjamin Jaffray
Jerry Johnson, Treasurer
William T. Katsiyiannis, MD
D. William Kaufman
Thomas A. Keller, III
Maureen Kucera-Walsh
Casey M. Lawler, MD
Rick Leggott
Richard Meyer, Ex-Officio
Michael R. Mooney, MD
Stuart Nolan, Past Chair
Cindy Piper
Colleen Sargent
Robert Scott, MD
John Seaberg
Steve Sjoblad
Archie Smith
Timothy M. Sullivan, MD
James V. Toscano, President
Emily Anne Tuttle
Sheldon Z. Wert
Minneapolis Heart Institute® and
Minneapolis Heart Institute Foundation Physicians
A special thanks to these physicians who have made significant contributions to philanthropy,
research and education at MHIF.
Raed H. Abdelhadi, MD
Peter B. Alden, MD
Jason Q. Alexander, MD
Adrian K. Almquist, MD
Richard Y. Bae, MD
John E. Bernhardson, MD
Shalini Bobra, MD
M. Nicholas Burke, MD
Durand E. Burns, MD
Barry M. Cabuay, MD
Ivan J. Chavez, MD
Andrew H. Cragg, MD
James A. Daniel, MD
Timothy G. Dirks, MD
Frazier Eales, MD
David S. Feldman, MD, PhD
Thomas F. Flavin, MD
Björn P. Flygenring, MD
James A. Furda, MD
Charles C. Gornick, MD
John N. Graber, MD
Kevin J. Graham, MD
Elizabeth Z. Grey, MD
Kevin M. Harris, MD
Robert G. Hauser, MD
Timothy D. Henry, MD
William T. Hession, MD
Mark A. Houghland, MD
Kasia Hryniewicz, MD
David G. Hurrell, MD
Desmond B. Jay, MD
Randall K. Johnson, MD
William T. Katsiyiannis, MD
Thomas Knickelbine, MD
Vibhu R. Kshettry, MD
Casey M. Lawler, MD
John R. Lesser, MD
David Lin, MD
Daniel L. Lips, MD
Terrence F. Longe, MD
James D. Madison, MD
Barry J. Maron, MD
Daniel Melby, MD
Nader Moazami, MD
Michael R. Mooney, MD
Richard R. Nelson, MD
Marc C. Newell, MD
Quirino G. Orlandi, MD
Luis A. Pagan-Carlo, MD
Wesley R. Pedersen, MD
Anil K. Poulose, MD
Adnan Z. Rizvi, MD
Robert S. Schwartz, MD
Esther Shao, MD
Scott W. Sharkey, MD
Peter J. Stokman, MD
Timothy M. Sullivan, MD
Benjamin Sun, MD
Chuen Y. Tang, MD
Norma L. Thiessen, MD
Jay H. Traverse, MD
Alexander S. Tretinyak, MD
Robert A. Van Tassel, MD
Yale L. Wang, MD
Contributors
m a k i n g a d i f f e r e n c e . o n e s u p p o rt e r at a t i m e .
MHIF is profoundly grateful for the financial contributions made
by individuals and organizations who share our commitment
to creating a world without heart disease.®
This year, in an effort to conserve paper and valuable donor resources, we are pleased to recognize
each donor on our website at www.mplsheart.org/2010annualreport
It is time.
920 E 28th St Ste 100 • Minneapolis, MN 55407
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