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Hajar Ashraf Gad – 12G
Virtual Pathology Lab
Step 1: Choose Case
Step 2: Examine Smear under Microscope
Hajar Ashraf Gad – 12G
Step 3: Find a Similar Diagram in Hematopathology Manual
Step 4: Make Diagnosis
Hajar Ashraf Gad – 12G
Journal Questions
1. In what ways do normal red and white blood cells
differ?
- Function: Red blood cells carry oxygen to the whole
body, and white blood cells defend the body against
viruses and infections.
- Amount: There are far more RBCs than WBCs in a
human body.
- Structure: WBCs are larger than RBCs and are
translucent because they lack hemoglobin and
contain nuclei unlike RBCs (they do not have nuclei).
2. Which type of white blood cell would you expect to be
most common in a normal blood smear?
- I would expect to find neutrophil cells.
3. A differential count of white blood cells from a patient
gave the absolute number of lymphocytes as 8000 per
mm3 and the total number of white blood cells as
12,000 per mm3. Calculate the percentage of
lymphocytes in this sample of white blood cells. Is this a
normal or abnormal percentage? Explain your answer.
- Percentage of lymphocytes = 8000/12000
100=66.67%.
- The normal value of lymphocytes in the blood is 20%40%, so this would be an abnormal percentage.
Hajar Ashraf Gad – 12G
4. Describe the difference between a communicable
disease and an inherited disease. Use examples you
have studied in this exploration to support your
description.
- A communicable disease is a disease that is
transmitted from person to person. Ex: malaria
- An inherited disease is a disease that is passed
through genetics. Ex: sickle cell anemia
5. Why are white blood cells in stained blood smears
usually counted at low power under a microscope?
Explain your answer.
- WBCs are bigger than all other blood cells, so on low
power, WBCs are visible while the other cells are
much less visible.
6. Why is the presence of a larger than normal number of
neutrophils indicative of an infection? Explain your
answer.
- Neutrophil cells are responsible for destroying
infectious agents in the body. The body produces
neutrophils to combat infections; therefore, a large
presence of neutrophils indicates that there is an
infection being fought against.
Hajar Ashraf Gad – 12G
7. Why would you not expect to see tissue macrophages in
blood smears? Explain your answer.
- Macrophages are not visible in blood smears because
tissue macrophages are not in the blood (they move
in tissues), and blood smears are a snapshot of what is
going on in the bloodstream.