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Rise in blood glucose levels Fall in blood glucose levels Detected by α cells in the islets of Langerhans in the pancreas This raises the glucose concentration in the blood Glucagon binds to specific target cells / receptors on the liver cell membranes Detected by β cells in the islets of Langerhans in the pancreas Also, glucagon promotes the formation of new glucose (gluconeogenesis) from fatty acids and amino acids α cells release glucagon which travels in the blood Rise in blood glucose levels Fall in blood glucose levels Detected by α cells in the islets of Langerhans in the pancreas Glucagon binds to specific target cells / receptors on the liver cell membranes Detected by β cells in the islets of Langerhans in the pancreas Also, glucagon promotes the formation of new glucose (gluconeogenesis) from fatty acids and amino acids α cells release glucagon which travels in the blood This lowers the glucose concentration in the blood The membrane of liver and muscle cells become more permeable to glucose, so glucose is absorbed This lowers the glucose concentration in the blood The membrane of liver and muscle cells become more permeable to glucose, so glucose is absorbed This raises the glucose concentration in the blood β cells release insulin which travels in the blood An enzyme converts glycogen to glucose (glycogenolysis) Also, an enzyme converts glucose to glycogen (glycogenesis) Insulin binds to specific target cells / receptors on the liver and muscle cell membranes β cells release insulin which travels in the blood An enzyme converts glycogen to glucose (glycogenolysis) Also, an enzyme converts glucose to glycogen (glycogenesis) Insulin binds to specific target cells / receptors on the liver and muscle cell membranes