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MASTER TEACHING NOTES Detailed Lesson Plan Chapter 21 Anaphylactic Reactions 50–65 minutes Case Study Discussion Teaching Tips Discussion Questions Class Activities Media Links Knowledge Application Critical Thinking Discussion Chapter 21 objectives can be found in an accompanying folder. These objectives, which form the basis of each chapter, were developed from the new Education Standards and Instructional Guidelines. Minutes Content Outline I. 5 15 Master Teaching Notes Introduction Case Study Discussion A. During this lesson, students will learn about assessment and emergency care for patients suffering from allergic reaction. B. Case Study 1. Present The Dispatch and Upon Arrival information from the chapter. 2. Discuss with students how they would proceed. II. Anaphylactic Reaction—Pathophysiology of Anaphylactic Reaction A. The immune system is a defense mechanism to fight off invasion by foreign substances. B. Antigens are foreign substances that are recognized by the cells of the immune system and eventually destroyed. C. When an antigen enters the body, it sets off an immune response, and the immune system produces antibodies, proteins that search for the antigen, combine with it, and help to destroy it. D. If an allergen, a type of antigen, enters the body, it can cause an abnormal response by the immune system known as an allergic reaction. E. An allergic reaction is a misdirected and excessive response by the immune system to an allergen. The response can be local or systemic. F. A life-threatening allergic reaction is known as an anaphylactic reaction (also anaphylaxis or anaphylactic shock). 1. Swelling in the upper and lower airways can cause breathing difficulties and hypoxia. 2. Dilated blood vessels and capillaries can decrease blood pressure and cause shock. G. Sensitization 1. An allergic reaction usually does not occur the first time the body is exposed to and produces antibodies against a particular antigen. 2. Hypersensitivity can develop upon first exposure, meaning if the person PREHOSPITAL EMERGENCY CARE, 9TH EDITION DETAILED LESSON PLAN 21 What is your general impression of the patient? What is the first action you should take? Weblink Go to www.bradybooks.com and click on the mykit link for Prehospital Emergency Care, 9th edition to access a web resource on the immune system and allergic reactions. Discussion Question What is the relationship between an allergic reaction and anaphylaxis? Video Clip Go to www.bradybooks.com and click on the mykit link for Prehospital Emergency Care, 9th edition to access a video on allergic rhinitis. PAGE 1 Chapter 21 objectives can be found in an accompanying folder. These objectives, which form the basis of each chapter, were developed from the new Education Standards and Instructional Guidelines. Minutes Content Outline Master Teaching Notes is again exposed to the antigen, an allergic reaction will occur. 3. The process of developing hypersensitivity on first exposure to an antigen is known as sensitization and primes the patient for a possible anaphylactic reaction. 4. During sensitization, antibodies attach to mast cells and basophils. When the antigen is reintroduced into the body, the cell membranes break down and release chemical mediators (such as histamine) that cause the signs and symptoms of anaphylaxis. 5. Life-threatening responses from the chemical mediators include bronchoconstriction, increase in capillary permeability, and vasodilation. H. Anaphylactoid reaction 1. Sometimes mast cells and basophils can release chemical mediators the first time the antigen is introduced into the body without the patient ever being sensitized. This is referred to as an anaphylactoid reaction. 2. Signs, symptoms, and treatment are exactly the same as for anaphylactic reaction. 3. See Table 21-1 for substances that commonly cause anaphylactoid reactions. I. Causes of anaphylactic reaction 1. Some causes of anaphylactic reaction are idiopathic (cannot be identified). 2. How antigens enter the body a. Injection b. Ingestion c. Inhalation d. Contact (absorption) 3. Common causes of anaphylactic reaction a. Venom b. Foods c. Pollen d. Medications (penicillin) e. Other substances (glue) f. Exercise g. Latex PREHOSPITAL EMERGENCY CARE, 9TH EDITION DETAILED LESSON PLAN 21 Critical Thinking Discussion How does the body’s response to an allergen result in signs and symptoms of anaphylaxis? Discussion Question What are some common causes of anaphylaxis? Animation Go to www.bradybooks.com and click on the mykit link for Prehospital Emergency Care, 9th edition to access an animation on anaphylactic reaction. PAGE 2 Chapter 21 objectives can be found in an accompanying folder. These objectives, which form the basis of each chapter, were developed from the new Education Standards and Instructional Guidelines. Minutes Content Outline Master Teaching Notes III. Anaphylactic Reaction—Assessment-Based Approach to 20 Anaphylactic Reaction A. Scene size-up 1. Be certain your own safety is not in jeopardy (especially if anaphylactic reaction is the result of a bite or sting). 2. Look for clues at the scene such as medications. B. Primary assessment 1. Patient may complain of not feeling well or malaise, generalized feeling of weakness or discomfort. 2. Closely assess the airway for signs of obstruction (stidor or crowing sounds). 3. Positive pressure ventilation may be necessary to force the air past the swollen upper airway. 4. If breathing is adequate, place the patient on a nonrebreather mask with an oxygen flow of 15 lpm. 5. Management of the airway may require endotracheal intubation, placement of a tube in the trachea to facilitate breathing. In most jurisdictions, this is performed by ALS. 6. Common signs of allergic reaction a. Rapid and weak pulse (fluid loss) b. Warm, flushed skin (vasodilation) c. Hives (capillary permeability and leaking in the epidermis) d. Edema (capillary permeability and leaking in the dermis) 7. Patient with an anaphylactic reaction is considered priority; consider calling ALS. 8. Determine if the patient has an epinephrine auto-injector and locate it immediately. C. Secondary assessment 1. If the patient is experiencing a severe reaction, conduct the secondary assessment en route to the hospital. 2. History a. Use the OPQRST line of questioning, with emphasis on the onset of the reaction. b. The faster the onset of signs and symptoms of an anaphylactic reaction, the more severe and prolonged the reaction will probably be. c. Take the patient’s SAMPLE history. PREHOSPITAL EMERGENCY CARE, 9TH EDITION DETAILED LESSON PLAN 21 Class Activity Provide ample opportunity for students to practice skills. PAGE 3 Chapter 21 objectives can be found in an accompanying folder. These objectives, which form the basis of each chapter, were developed from the new Education Standards and Instructional Guidelines. Minutes Content Outline Master Teaching Notes 3. Signs and symptoms a. Skin i. Warm, tingling feeling in face, mouth, chest, feet, and hands ii. Intense itching iii. Hives iv. Flushed or red skin v. Swelling to the face, lips, neck, hands, feet, and tongue b. Respiratory system i. “Lump in the throat” ii. Tightness in the chest iii. High-pitched cough iv. Tachypnea v. Labored breathing vi. Noisy breathing vii. Impaired ability to talk or hoarseness viii. Excessive amounts of coughed-up mucus ix. Partially or completely occluded airway x. Difficulty in breathing c. Cardiovascular system i. Tachycardia ii. Hypotension iii. Irregular pulse iv. Absent radial pulse d. Central nervous system i. Increased anxiety ii. Lightheadedness iii. Unresponsiveness iv. Disorientation v. Restlessness vi. Seizures vii. Headache e. Gastrointestinal system i. Naseau/vomiting ii. Abdominal cramping iii. Diarrhea iv. Difficulty in swallowing v. Loss of bowel control f. Genitourinary system PREHOSPITAL EMERGENCY CARE, 9TH EDITION DETAILED LESSON PLAN 21 Discussion Question What are signs and symptoms of anaphylaxis? Weblink Go to www.bradybooks.com and click on the mykit link for Prehospital Emergency Care, 9th edition to access a web resource on urticaria. PAGE 4 Chapter 21 objectives can be found in an accompanying folder. These objectives, which form the basis of each chapter, were developed from the new Education Standards and Instructional Guidelines. Minutes Content Outline Master Teaching Notes i. Urgent need to urinate ii. Cramping of the uterus g. Generalized signs and symptoms i. Itchy, watery eyes ii. Runny or stuffy nose iii. Sense of impending doom iv. Complaints of “not feeling well” v. General weakness or discomfort vi. Physical exam vii. Baseline vital signs h. Two key categories of signs and symptoms i. Airway and respiratory compromise—Airway occlusion; respiratory distress or respiratory failure with possible wheezing or stridor ii. Shock (hypoperfusion—Absent or weak pulses; rapid heartbeat; decreased blood pressure; deteriorating mental status 4. Physical exam a. Focus the physical exam on the patient’s complains involving the airway, breathing, and circulation. b. The EMT’s major concerns are a compromised airway, inadequate breathing, and shock (hypoperfusion). c. Check the face for swelling and extremities for bites, stings, or injection marks. d. Check pulses and skin temperature, color, and condition for indications of shock. 5. Baseline vital signs—Pay particular attention to the breathing, pulse, and blood pressure. 6. Remember that what appears to be a mild allergic reaction can progress to a severe, life-threatening reaction within minutes. Do not mistake anaphylaxis for other conditions with similar signs and symptoms. D. Emergency medical care 1. Distinguish between a mild and a moderate-to-severe reaction. 2. The mild reaction typically does not require aggressive intervention or administration of medication. Maintain an open airway, provide oxygen, and transport as soon as possible. 3. Emergency care for a moderate to severe reaction. a. Maintain a patent airway. b. Suction any secretions. PREHOSPITAL EMERGENCY CARE, 9TH EDITION DETAILED LESSON PLAN 21 PAGE 5 Chapter 21 objectives can be found in an accompanying folder. These objectives, which form the basis of each chapter, were developed from the new Education Standards and Instructional Guidelines. Minutes Content Outline Master Teaching Notes c. Maintain oxygen therapy. d. Be prepared to assist ventilation. e. Administer epinephrine by a prescribed auto-injector (on-line or offline order). f. Consider calling for advanced life support. g. Initiate early transport. E. Reassessment 1. Patient with a mild reaction should be constantly monitored for indications that the reaction is worsening and that further intervention may be needed. 2. Patient with moderate-to-severe reaction who has received an epinephrine injection should be reassessed to determine if the injection has been effective (after two minutes). 3. Closely reassess the airway, breathing, and circulation status and looks for signs of deterioration. 5 15 Discussion Question What are the treatment priorities for patients with anaphylaxis? IV. Anaphylactic Reaction—Summary: Assessment and Care A. Review assessment findings that may be associated with allergic reaction and emergency care for allergic reaction. B. See Figures 21-3 and 21-4. Knowledge Application V. Anaphylactic Reaction—Epinephrine Auto-Injector A. Epinephrine is the drug of choice for the emergency treatment of moderateto-severe allergic reactions. B. Epinephrine’s alpha1 and alpha2 properties cause vasoconstriction and tighten the capillaries, reversing the increased capillary permeability experienced by the anaphylactic patient. C. The beta2 properties cause bronchodilation, reversing the bronchoconstriction. D. The beta1 properties are responsible for side effects from administration. E. Epinephrine also reduces the effects of antihistamine. F. Body’s response to epinephrine is rapid; however, it only lasts ten to 20 minutse. G. Epinephrine comes packaged in a disposable delivery system for selfadministration (EpiPen® and Twinject®) 1. Autojectors with spring-loaded, concealed needle designed to deliver a precise dose of epinephrine Teaching Tip PREHOSPITAL EMERGENCY CARE, 9TH EDITION DETAILED LESSON PLAN 21 Given a scenario involving exposure to an allergen, students should be able to determine treatment priorities for the patient. Pass around examples of epinephrine autoinjectors for students to see and handle. Critical Thinking Discussion What are the actions of epinephrine that are beneficial to the patient with anaphylaxis? Weblink Go to www.bradybooks.com and click on the mykit link for Prehospital Emergency Care, 9th edition to access a web resource on the epinephrine autoinjector and anaphylaxis. PAGE 6 Chapter 21 objectives can be found in an accompanying folder. These objectives, which form the basis of each chapter, were developed from the new Education Standards and Instructional Guidelines. Minutes Content Outline Master Teaching Notes 2. Twinject® is unique because it carries two doses of epinephrine. 3. Both epinephrine auto-injectors carry a 0.3 mg dose for patients 66 pounds or greater and 0.15 mg for infants and children up to 66 pounds. 4. Activated by pressing it against the patient’s thigh (lateral portion, midway between the hip and knee preferred); second dose of Twinject® requires additional steps 5. Preferable to move clothing from the injection site but not necessary. VI. 5 Follow-Up Animation Go to www.bradybooks.com and click on the mykit link for Prehospital Emergency Care, 9th edition to access an animation on allergic reactions and epinephrine. Case Study Follow-Up Discussion A. Answer student questions. B. Case Study Follow-Up 1. Review the case study from the beginning of the chapter. 2. Remind students of some of the answers that were given to the discussion questions. 3. Ask students if they would respond the same way after discussing the chapter material. Follow up with questions to determine why students would or would not change their answers. C. Follow-Up Assignments 1. Review Chapter 21 Summary. 2. Complete Chapter 21 In Review questions. 3. Complete Chapter 21 Critical Thinking. D. Assessments 1. Handouts 2. Chapter 21 quiz Why is the immediate application of oxygen an important aspect of Mrs. Stein’s treatment? What is the significance to Mrs. Steins’ treatment and recovery of the inability to pinpoint the exact time the symptoms began? Class Activity Alternatively, assign each question to a group of students and give them several minutes to generate answers to present to the rest of the class for discussion. Teaching Tips Answers to In Review and Critical Thinking questions are in the appendix to the Instructor’s Wraparound Edition. Advise students to review the questions again as they study the chapter. The Instructor’s Resource Package contains handouts that assess student learning and reinforce important information in each chapter. This can be found under mykit at www.bradybooks.com. PREHOSPITAL EMERGENCY CARE, 9TH EDITION DETAILED LESSON PLAN 21 PAGE 7