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COVENANT UNIVERSITY
COLLEGE OF SCIENCE AND TECHNOLOGY
DEPARTMENT OF BIOLOGICAL SCIENCES
MICROBIOLOGY PROGRAMME
COURSE COMPACT
COURSE CODE:
MCB 311
COURSE TITLE:
MICROBIAL PHYSIOLOGY AND METABOLISM
UNITS:
3
SEMESTER/ SESSION:
ALPHA SEMESTER 2014/2015
COURSE LECTURERS: Dr. A.A. Ajayi and Miss M.O. Adedeji
COURSE CO-ORDINATOR: Dr. A.A. Ajayi
TIME:
THURSDAYS 8-10AM
LOCATION:
HALL 107
A.
B.
BRIEF OVERVIEW OF COURSE:
Microbial nutrition and growth. Generation of energy for metabolism,
transport system, thermodynamics and enzyme- catalyzed reactions.
Fermentation and biosynthesis.
COURSE OBJECTIVE/ GOAL:
At the end of the course students are expected to:
 Classify microorganisms based on nutrient requirements.
 Formulate growth media from the knowledge of microbial growth
Requirements
 Apply the principle of thermodynamics in microbial growth and metabolism
 Know the role of enzyme in biosynthesis
 Explain the energy cycle and why energy is essential in biosynthesis
 Explore the application of microbial metabolism in pharmaceuticals, food,
environment and fermentation based industries
C.
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METHOD OF LECTURE DELIVERY/ TEACHING AID:
Guided instruction.
Interactive classroom session.
Multimedia
Laboratory session.
D.
COURSE OUTLINE
Module 1
Microbial Nutrition and growth
Week 1
Week 2
Week 3
Module 2
Week 4
Week 5
Week 6
Nutritional requirements of microorganisms and growth
factors.
Transport of nutrients in microorganisms based on nutrient
requirement
Microbial growth and conditions necessary for growth
Generation of Energy
An overview of metabolisms, the break down of glucose to
Pyruvate
Tricarboxylic acid cycle, electron transport and oxidative
phosphorylation.
Fermentation and Biosynthesis
Dr. A.A. Ajayi
Week 7
Module 3
Mid semester Test
Energy and enzymes
Week 8
The energy cycle and the laws of thermodynamics. How
free energy is used in reaction. The role of ATP in
metabolism
Week 9
Oxidation reduction reaction and electron carriers
Week 10
Enzymes- Structure and classification mechanisms of
enzymes reaction
Factors affecting enzymes activities
Miss. M.O. Adedeji
Week 11
Week 12
Week 13
Revision
Examination week
E.
STRUCTURE OF THE PROGRAMME/ METHOD OF READING
1. Continuous Assessment
30 Marks
- Class assignments 10 marks
- Mid semester Test 20 marks
2. Semester Examination
70 Marks
F.
GROUND RULES AND REGULATIONS
 Student must make at least 80% attendance in lecture and laboratory
session
 There must be no eating or drinking in classrooms or laboratory
 Student must participate actively when placed to work in groups.
 All assignment must be submitted within the stipulated time.
G.
TOPICS FOR TERM PAPERS/ ASSIGNMENTS/ STUDENTS
ACTIVITIES
 Factors affecting enzyme activity
 The growth of unicellular bacteria in a liquid medium
H.
ALIGNMENT WITH UNIVERSITY VISION AND GOALS
Training in Microbial physiology will give students an overview of what is all
about and it will equip them for good performance in other courses in
microbiology as they move on in their pursuit of a degree in microbiology.
I.
INDUSTRIAL RELEVANCE
- A well-grounded knowledge of the basics of Microbial physiology is a
prerequisite for leadership position in pharmaceuticals, food companies,
oil companies, hospitals, diagnostic laboratory and research institutes.
J.
RECOMMENDED READING
- Microbiology: Michael j. Pelczar jr. Ecs Chan, Noel R, Krieg
- Enzymes: Dixon and Webb
- Principles of Biochemistry: Geoffrey L. Zubay, William W. Parson,
Dennis E. Vance