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Creation of a new Barrett esophageal cancer cell line at Hopkins – JHU-EsoAd1. Previous cell lines designated as “esophagus cancer” have been frequently from other types of cancer!!!! Identification of Mesothelin as a new biomarker for Barrett esophagus and cancer A B C D Targeting mesothelin with antibody-conjugated nanoparticles for imaging A B C Nanoparticles of curcumin (“nanocurcumin”) for chemoprevention of Barrett esophagus Curcumin is the major yellow pigment found in ordinary turmeric and curry! Free curcumin in water Nanocurcumin Nano-polypill (Doxorubicin plus curcumin nanoparticles) for therapy of Barrett esophagus Cancer cells exposed to novel nano-polypill Red = doxorubicin Green - curcumin Merged
