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Information for patients colonised / infected with Carbapenem Resistant Enterobacteriaceae (CRE) What are Carbapenem Resistant Enterobacteriaceae? There are many bacteria that live naturally and harmlessly in the gut of humans; however, if the bacteria get into the wrong place, such as the bladder or bloodstream they can cause infection. Carbapenems are one of the most powerful types of antibiotics. Carbapenemase enzymes (chemicals), made by some strains of bacteria, allow the bacteria to destroy the carbapenem antibiotics. These bacteria are said to be resistant to antibiotics. Carbapenem resistant organisms can live harmlessly in the gut; it is referred to as colonisation if these are found during screening. Why does Carbapenem resistance matter? Carbapenem antibiotics can only be given in hospital directly into the bloodstream. Until now, doctors have relied on them to successfully treat certain infections when other antibiotics have failed to do so. In a hospital there are many vulnerable patients and the spread of resistant bacteria can cause problems. Does colonisation with Carbapenem Resistant Enterobacteriaceae need treating? If a person is colonised with Carbapenem resistant Enterobacteriaceae (called CRE), they do not need to be treated. However, if the bacteria have caused an infection then antibiotics will be required. How did I ‘pick up’ a Carbapenem Resistant Enterobacteriaceae? Sometimes these bacteria can be found living harmlessly living in the gut and so it can be difficult to say when or where you picked it up. However, there is an increased chance of picking up these bacteria if you have been a patient in a hospital abroad or in a UK hospital that has had patients carrying the bacteria, or if you have been in contact with a carrier elsewhere. How will I be cared for in hospital? You will be cared for in a single room with your own toilet facilities whilst in hospital. You made be asked to provide a number of samples, depending on your length of stay, to check if you are still carrying the bacteria. These will be taken on a weekly basis if you remain in hospital. Samples can either be a taking a rectal swab inserted just inside your rectum (bottom) or by a sample of faeces; it may also include swabs from other areas, such as drip sites (if you have one). You will normally be informed of the result with 3 days. How can the spread of Carbapenem Resistant Enterobacteriaceae be prevented? Caring for you in a single room helps to prevent the spread of the bacteria. Healthcare workers will decontaminate their hands regularly. They will use long sleeved gowns and gloves when caring for you. The most important measure for you to take is to wash your hands well with soap and water, especially after going to the toilet. Visitors will be asked to wash their hands on entering and leaving the room and will be asked to wear gloves and apron. What about when I go home? Whilst there is a chance that you may still be colonised when you go home quite often this will go away with time. No special measures or treatment are required; any infection will have been treated prior to your discharge. You should carry on as normal, maintaining good hand hygiene. Whenever you come into contact with a healthcare professional, e.g. GP, Hospital staff, ambulance staff, district nurses, it is important that you make them aware of the CRE result. Should you or a member of your household be admitted to hospital, you should let the hospital staff know that you are, or have been colonised with CRE previously Where can I find more information? If you would like further information please speak to a member of your care staff, who will contact the Infection Prevention and Control Team for you. The Public Health England website is another source of information: www.hpa.org.uk/Topics/InfectiousDiseases/InfectionsAZ/CarbapenemResistance/ September 2014 © Copyright 2014 All rights reserved. No part of this publication may be reproduced in any form or by any means without prior permission in writing from Infection Control, Derby Hospitals NHS Foundation Trust.