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Transcript
SEMINAR ON WORLD WIDE
DANGER OF ARSENIC POISONING
IN WATER AND SUSTAINABLE
SOLUTIONS
ORGANIZED BY
ACADEMY OF HEALTHY WATER,
ECOSYSTEM AND ENVIRONMENT
DERBY, KANSAS, USA
CANCER RISKS
FROM ARSENIC
IN DRINKING
WATER
Environmental exposures
 Cancer risks:
 Tobacco smoke
 Radon in homes
 Arsenic
Lifetime risks of dying from cancer due
to environmental exposures
 Tobacco smoke:
 Low exposure = 4/1000
 High exposure = 10/1000
 Radon in homes:
 Average exposure = 3/1000
 High exposure = 20/1000
 Arsenic in drinking water:
 U.S. estimated average = 1/1000
 U.S. water standard = 21/1000
ARSINIC
 Organic form
 Inorganic forms
 More toxic
Drinking water
contaminated with Arsenic





Skin
Lung
Liver
Kidney
Other organs
SKIN CANCER
 First described in 1888 in patients treated
with arsenical mixtures for skin conditions
 Arsenic from water supplies and drugs is
known to cause skin cancer
 Prevalence among highly exposed males
aged >60 reached 25%
Liver cancer
 Liver Cancer
 Angiosarcoma
 Supported by a series of case reports
 Winegrowers in Germany
 Taiwan
Lung Cancer
 Ingestion:
 Water supplies
 Comparable to tobacco smoke and radon
 Inhalation:
 Smelters
Kidney and Bladder
Cancer
 There is a clear relationship
between arsenic water levels and
bladder and kidney cancer
CONCLUSION
 Results from epidemiological studies, showed
persuasive evidence that inorganic arsenic is a
cause of human cancer at several sites.
 There is strong evidence supporting a causal
relationship between ingested arsenic and cancer
of skin, liver, lung cancer.
 There is some evidence from Taiwan supporting a
causal relationship between ingested arsenic and
cancer of kidney and bladder cancer.
Is Arsenic Useful?
 Industry
 Medicine
 Leukemia (Arsenic Trioxide, Trisenox)
 Autoimmune diseases