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UVa BME LABS GUIDE for Undergraduate Students. Last Updated 10/10/2012.
Director
Acton, Scott
[email protected]
Student Contact
Projects
(434) 982-2003
Emmanuel Denloye-Ito
[email protected]
Biomedical image analysis, image processing.
Website: http://viva.ee.virginia.edu.
Director
Berr, Stuart
[email protected]
Projects
Students/Yr 2 per year
Academic Year: 5-10 hours/week.
Hours/Wk
How to find out about current needs
Talk to Dr. Acton.
Paid, Volunteer, or For Credit?
Paid (sometimes), volunteer or for credit.
Tracking cells, classifying MR images, analyzing imagery. Recommended that students take ECE 323/324 or equivalent.
Research
Student Contact
Lab VIVA: Virginia Image and Video Analysis
Thornton E-309
434 924-5096
Landon Locke
[email protected]
Lab Small Animal MRI Lab
MR4, Room 1192
Students/Yr 2 per year
10 hours/week.
Hours/Wk
How to find out about current needs
Talk to Dr. Berr.
Paid, Volunteer, or For Credit?
Mostly volunteer or for credit. Occasional paid position.
Develop high resolution MR imaging techniques for phenotyping mice.
Research
Cardiovascular and cancer research in mice. In vivo magnetic resonance, bioluminescence, and flourescence imaging.
Director
Blemker, Silvia
[email protected]
Student Contact
Projects
434-924-6291
Handsfield, Geoffrey
[email protected]
Lab 'M3: Multiscale Muscle Mechanics Lab'
MR5 2313
Students/Yr 1-3
10 hours/week
Hours/Wk
How to find out about current needs
Contact Dr. Blemker.
Paid, Volunteer, or For Credit?
Volunteer or for credit.
'Image processing of MRI images for creating 3D datasets of in vivo muscle, mechanical modeling, MRI image acquisition'
Research
We characterize the relationships between muscle structure, mechanical properties, biology, and function. We are applying these findings to understanding and improving the treatments for
musculoskeletal impairments associated with movement disorders, such as cerebral palsy. We are integrating a variety of computational and experimental approaches, including
computational models, MRI techniques, and anatomical measurements and tissue testing.
Website: http://www.mae.virginia.edu/muscle/
Director
Crandall, Jeff & Kent, Rich
[email protected]
Student Contact
Projects
Research
Director
Sabrina Lau, [email protected]
Projects
Research
Lab Automobile Safety Lab
North of the airport!
Students/Yr 2-3 per year
How to find out about current needs
Contact Rich Kent or Jeff Crandall.
Paid, Volunteer, or For Credit?
Paid, volunteer, and for credit.
Hours/Wk
Development of constitutive models for biological materials, development of injury criteria/thresholds, assessment of crash test dummies, design of test apparatus/methods. Note: Lab is offgrounds, north of the airport!
Biomechanics, Injury Biomechanics, Trauma Prevention, Automobile Safety. http://auto-safety.mech.virginia.edu
Website: http://www.centerforappliedbiomechanics.org/
Epstein, Fred H.
[email protected]
Student Contact
434 296-7288
434 982-0563
Naresh, Nivedita
[email protected]
Lab Epstein Lab
MR5 1223
Students/Yr 1 per year
How to find out about current needs
Contact Dr. Epstein.
Paid, Volunteer, or For Credit?
Usually volunteer or for credit.
Develop Matlab software for image analysis.
Use of MRI to image myocardial function and perfusion.
Website: http://www.medicine.virginia.edu/clinical/departments/radiology/research/home.html
Hours/Wk
Director
French, Brent A.
[email protected]
Student Contact
434 924-5728
Bryan Piras
[email protected]
Lab Molecular Bioengineering Laboratory
MR5, Room 1219
Students/Yr 1 per year
10 hours/week.
Hours/Wk
How to find out about current needs
Contact by email: [email protected].
Paid, Volunteer, or For Credit?
Mostly volunteer or for credit.
Research
Depends largely on student's aptitude, experience, and inclination. Projects range from studying gene expression at the mRNA and protein levels to studying cardiac function with magnetic
resonance imaging.
Roles of oxidative stress and inflammation in myocardial infarction and left ventricular remodeling.
Director
Gillies, George T.
Projects
[email protected]
434 924-7634
Student Contact
Lab Bio/Thermal Fluids Lab
MEC 105D
Students/Yr 3 per year
Minimum of 4-6 hours/week.
Hours/Wk
How to find out about current needs
See Dr. Gillies.
Paid, Volunteer, or For Credit?
Volunteer and For credit only.
Projects
Research
Research interests include medical device development and precision measurement technology. More specifically, they include magnetic guidance systems for medical implants, design of
catheters for positive pressure infusion systems, novel methods for delivering therapies into brain tumors, design of instrumentation systems for epicardial electrophysiology, and the
development and testing of neurosurgical instrumentation.
Director
Guilford, William H.
[email protected]
Student Contact
Projects
434 243-2740
Amy Clobes
[email protected]
Lab Molecular Biomechanics Laboratory
MR5, Room 1213
Students/Yr 2 per year
2 afternoons/week minimum.
Hours/Wk
How to find out about current needs
Projects are continually evolving. Contact Dr. Guilford.
Paid, Volunteer, or For Credit?
Volunteer or for credit. Possible to be paid, but only
Projects range from the molecular basis of heart and neural diseases, to the development of computer algorithms for tracking images of single molecules.
Research
The molecular basis of muscle contraction and cell adhesion, and its relationship to cardiovascular disease.
Website: http://faculty.virginia.edu/guilford/
Director
Helmke, Brian P.
[email protected]
Student Contact
434 924-1726
Rachel Evans
[email protected]
Lab Cellular Mechanotransduction
MR5, Room 1207
Students/Yr 1-2 per year
10 hours/week.
Hours/Wk
How to find out about current needs
Contact Dr. Helmke.
Paid, Volunteer, or For Credit?
Depends: mostly volunteer or for credit.
Research
Recent undergraduate projects include imaging nitric oxide production inside endothelial cells, imaging structural deformation inside cells during "tickling" with a micropipette, creating
micropatterned surfaces to control cell adhesion, and investigating how white blood cell migration across the endothelium depends on cell structure.
Our lab is investigating how cells sense mechanical forces. In particular, we're interested in how endothelial cells lining the blood vessels sense changes in frictional shear stress due to blood
flow. This has important clinical implications since endothelial dysfunction plays a crucial role in the development of arterial diseases such as atherosclerosis. We are developing innovative
tools to investigate cell mechanics and control cell behavior, including high-resolution microscopy, 4-D image analysis, and nanotechnology.
Director
Holmes, Jeffrey
Projects
[email protected]
Student Contact
Projects
Research
434 243-6321
Tracy Burcin, Lab Manager
[email protected]
Lab Cardiac Biomechanics Group
MR5, Room 2334
Students/Yr 2
How to find out about current needs
Contact Dr. Holmes.
Paid, Volunteer, or For Credit?
Focuses on the interactions between mechanics, function, and growth and remodeling in the heart.
See faculty web page on BME website for current projects.
Lab website: http://bme.virginia.edu/holmes/
UVa BME Labs Guide for Undergraduate Students. Updated 10/10/2012. Page 2 of 6.
Hours/Wk
Director
Horwitz, Rick
[email protected]
434-243-6812
Student Contact
Projects
Research
Director
Students/Yr 1-2 per year
10 hours/week
Hours/Wk
How to find out about current needs
Contact post doc Alexia Bachir, [email protected]
Paid, Volunteer, or For Credit?
Paid, volunteer or for credit
Digital image analysis, adhesion turnover assays, implementation of computational image analysis tools. Depending on applicant possibility of live cell imaging, tissue culture, and
transfection protocols.
The lab studies cell migration and is interested in the mechanisms that control cell movement via cell-substrate adhesion formation, turnover and disassembly. The project will apply imaging
techniques to further understand the spatial and temporal distribution, dynamics and regulation of these processes during cell migration.
Hossack, John
[email protected]
Student Contact
Lab Cell Adhesion and Migration
Jordan Hall, Room 3226
434 243-5866
Ali Dhanaliwala
[email protected]
Lab Biomedical Ultrasound Laboratory
MR5, Room 2219
Students/Yr 1-2 per year
10 hours/week.
Hours/Wk
How to find out about current needs
www.faculty.virginia.edu/hossack/ & then contact Dr. Hossack
Paid, Volunteer, or For Credit?
Paid, volunteer, or for credit.
Research
Involve supporting some component of one of the active research projects listed below. Projects are best suited to those interested in imaging/mathematical modeling. Some projects are
available that involve assisting in the collection of clinical imaging data and analyzing it. There are openings in mouse heart imaging.
Various projects: quantitative 3D ultrasound imaging of mouse heart chambers, quantification of perfusion in mouse heart after myocardial infarction, breast and prostate cancer detection
using ultrasound-based measurements of elasticity, transducer modeling and design. Simulating the image formation process, finite element simulation of transducers (emphasis on high signal
bandwidth transducers). Collaborations with mouse researchers, Radiology and CV Division.
Website: http://bme.virginia.edu/hossack/
Director
Janes, Kevin
Projects
[email protected]
Student Contact
Projects
434 243-2126
Sameer Bajikar
[email protected]
Lab Cell-Signaling Bioanalysis Laboratory
MR5 2nd floor lab Hallway, Room 2014
Students/Yr 1-2
10 hours/week
Hours/Wk
How to find out about current needs
Email contact preferred. See Note below.
Paid, Volunteer, or For Credit?
Molecular cloning, image analysis Note: I am exclusively looking for long-term commitments (ideally, 2+ years).
Research
Our lab is interested in understanding how cells interpret their environment and respond accordingly. We design biochemical and cell-biological tools for tracking the molecular events that
underlie cell-signal processing.
Website: http://bme.virginia.edu/janes/index.html
Director
Kelly, Kimberly
[email protected]
Student Contact
434-243-9352
Soo Shin
[email protected]
Lab Targeted Molecular Imaging
MR5, Room 1129
Students/Yr
How to find out about current needs
Attend Lab Meeting & Contact Dr. Kelly
Paid, Volunteer, or For Credit?
Hours/Wk
Projects
Research
I am interested in applying powerful combinatorial approaches to the development and design of targeted, multimodal, and amplifiable imaging agents. Using this method of attack, I have
generated imaging agents capable of the early detection in vivo of colon, pancreatic, lung, and prostate cancers as well as specific targets in atherosclerosis and inflammation.
Director
Lawrence, Michael B.
[email protected]
Student Contact
Projects
Research
Caroline Whitaker
[email protected]
434 982-4269
Lab Adhesion Mechanics/Membrane Immunobiolgy
MR5, Room 2111
Students/Yr 2 per year
5 hours/week (one good afternoon).
Hours/Wk
How to find out about current needs
Contact Dr. Lawrence.
Paid, Volunteer, or For Credit?
Paid (summer only), volunteer or for credit.
Students choose a project based on their interests and current lab needs. Examples of previous undergraduate projects include the design of microbubbles and peptide-presenting hydrogels
with possible applications to targeted drug delivery. There are additional opportunities in modeling cell and microbead rolling and investigating the relationship between molecular structure
Role of shear stress in inflammation. Cell recruitment to sites of tissue injury. Targeted drug delivery. Progenitor cell homing.
Website: http://bme.virginia.edu/lawrence/
UVa BME Labs Guide for Undergraduate Students. Updated 10/10/2012. Page 3 of 6.
Director
Meyer, Craig H.
[email protected]
Student Contact
Projects
Research
Director
Student Contact
Projects
434 243-9495
Sam Fielden
[email protected]
Lab Cardiac Imaging Lab
MR5, Room 2228
Students/Yr 1-2 per year
5-10 hours/week.
Hours/Wk
How to find out about current needs
Contact Dr. Meyer.
Paid, Volunteer, or For Credit?
Mostly volunteer or for credit.
One technique we are studying is real-time interactive imaging, which allows images of the beating heart to be acquired, displayed and controlled in real-time.
Non invasive coronary angiography and coronary vessel wall imaging. Developing novel rapid MRI techniques.
[email protected]
Papin, Jason
Lab Computational Systems Biology Lab
MR5 2041
Students/Yr 2-4
More than 4
Hours/Wk
Matthew Biggs
[email protected]
How to find out about current needs
Email interests and resume/CV.
Paid, Volunteer, or For Credit?
Paid, volunteer, or for credit.
Model-building; high throughput data analysis; microbial growth cultures.
Research
Computational analysis of biochemical networks in cancer and infectious disease.
Website: http://bme.virginia.edu/csbl/index.php
Director
Peirce-Cottler, Shayn M.
[email protected]
Student Contact
434 243-5795
Peirce Lab shadowing is coordinated by Kitter
Kitter Bishop - [email protected]
Lab Peirce-Cottler Lab
MR5 2228
Students/Yr 2 during year; 2 during summer
5-20 hours/week, depending on project.
Hours/Wk
How to find out about current needs
Call, email, or visit www.bme.virginia.edu/peirce
Paid, Volunteer, or For Credit?
Paid volunteer, or for-credit
Research
Tissue engineering, cell culture, and assisting with small animal surgeries. Immunohistochemistry benchtop work (staining tissues with antibodies). Image analysis and data acquisition on
tissues. Computational modeling of tissue patterning events. Lab technician work.
Tissue Patterning, Stem Cells in Microvascular Growth, Computational Modeling of Complex Biological Systems. Advice from Dr. Peirce: Don't wait to get started. I recommend looking
Director
Price, Richard
Projects
for a project (or lab experience) in your first or second year, but it's never too late to start! Pick a lab that you are really interested in...do your research to figure out what scientific projects
(or questions) are really interesting to you. If you commit to working in a lab, make sure that you have the time to spend there and do your best work!
[email protected]
Student Contact
434 924-0020
Josh Meisner
[email protected]
Lab Microvascular Remodeling & Ultrasound-Mediated Therapies
MR5, Room 2216
Students/Yr 1-3 per year/per grad student
5-30 hours/week.
Hours/Wk
How to find out about current needs
Contact Dr. Price by email.
Paid, Volunteer, or For Credit?
Paid, volunteer or for credit.
Research
Often, projects involve assisting with small animal surgery, immunofluorescence, and microscopy for analyzing microvascular networks and applied ultrasound techniques. Additional areas
include developing image analysis tools, data processing, cell culture, and molecular biology techniques.
Our research spans multiple disciplines with one focus on determining the mechanisms of microvascular network growth and remodeling during both sprouting of new capillaries
(angiogenesis) and remodeling of existing arteries (arteriogenesis). Our second focus is the application of therapeutic ultrasound for targeted drug delivery, gene transfection, and ablation
therapy.
Director
Saucerman, Jeffrey
Projects
[email protected]
Student Contact
Projects
Research
Karen Ryall
[email protected]
434 924-5095
Lab Cardiac Systems Biology Lab
MR5 1123
Students/Yr 2
10 hours/week
Hours/Wk
How to find out about current needs
Email Dr. Saucerman
Paid, Volunteer, or For Credit?
Isolation and culture of muscle cells from rat hearts. Microscopy to image heart muscle cell contractions and remodeling. Computational modeling of biochemical pathways that lead to heart
disease.
Our lab combines experimental studies and computational modeling to understand how biochemical networks make decisions impacting the development of heart disease. This basic
research is helping us identify new therapeutic targets to prevent or reverse disease.
Website: http://bme.virginia.edu/saucerman/
UVa BME Labs Guide for Undergraduate Students. Updated 10/10/2012. Page 4 of 6.
Director
Williams, Mark B.
[email protected]
Student Contact
Projects
Research
Judy, Patty
[email protected]
434 982-4422
Lab Detector Lab
MR4 Room 1174
Students/Yr 3 - 5 per year
10 hours/week.
Hours/Wk
How to find out about current needs
Contact Dr. Williams.
Paid, Volunteer, or For Credit?
Paid, volunteer or for credit
Detector development and characterization, data acquisition and image analysis, software development, design and implementation of studies using both phantoms and patient volunteers.
Development of x-ray and gamma ray based medical imaging systems.
Website: http://www.faculty.virginia.edu/mbwlabwebsite/
UVa BME Labs Guide for Undergraduate Students. Updated 10/10/2012. Page 5 of 6.