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Patient Name DOB: 09/17/YYYY Talcum Case Review Case Report Parameter Findings First name XXXX Initial R Last name XXXX DOB 09/17/YYYY Gender Female Documentation of Talc No PDF Ref 13 Usage in medical records (Yes/No) Brand of talcum powder Not available used Diagnosed with Ovarian Yes –Right ovary dysgerminoma 17,16,15 02/18/YYYY (Per available medical records) 8-9 Cancer? Date of Diagnosis *Reviewer’s comment: Upon review of available records, we note patient was admitted on 02/18/YYYY for the surgical treatment of ovary dysgerminoma. Prior medical records are not available to know the exact date of diagnosis Stage of Cancer Not known Metastases (If any) As per the pathology report (Dated 02/19/YYYY), no evidence of 15 metastasis Other risk factors for Not available ovarian cancer (hormonal therapy, obesity, fertility medications) Treatment for Ovarian 02/19/YYYY: Exploratory laparotomy, right oophorectomy, 1 of 16 10-11 Patient Name DOB: 09/17/YYYY Parameter cancer Findings PDF Ref appendectomy, pelvic aortic node sampling and partial omentectomy Physical side effects of None cancer treatment Other Complications None (Talcosis/Respiratory problems) Death from Ovarian No cancer? Smoking history Has she ever been a tobacco user? Yes 8 Period of time smoking: Not available Heaviness of smoking: One or two in a month Brand of cigarettes smoked: Not available Has she quit smoking? Not available When did she quit? Not available Condition of the patient As on 02/27/YYYY, patient was discharged to home without any per last available record complaints following hospitalization for the surgical treatment of 7, 3 ovary dysgerminoma. Prescriptions given for Darvocet, Ferrous Gluconate and Colace with instruction to follow up with Dr. XXXXXX, M.D. after one month Reviewer’s comment: Medical records after 02/27/YYYY are not available to know the condition of the patient post surgical management of ovarian cancer. Patient History (As on Past Medical History: No significant illnesses. 02/18/YYYY) Prior Surgeries: Non-contributory. Family history: Not available Allergies: No known drug allergies. 2 of 16 8 Patient Name DOB: 09/17/YYYY Missing Medical Record: Is Record What Records Hospital/ Date/Time Why we need the Missing Hint/Clue that records are are Needed Medical Provider Period records? Confirmatory or missing Probable? To know the exact Office visits and diagnostic studies for abdominal Unknown complaints date of diagnosis Per operative report dated on Prior to and also 02/19/YYYY, We have noted 02/18/YYY treatments Y underwent for for her complaints and had abdominal diagnostic studies for the same Confirmatory that patient went to Gynecologist complaints After Medical records Unknown 02/27/YYY Y To know the post operative condition of the patient 3 of 16 Discharged on 02/27/YYYY Confirmatory with instruction to follow up with Dr. XXXXXX, M.D. after one month Patient Name DOB: 09/17/YYYY Detailed Chronology DATE PROVIDER 02/18/YYY XXXXXX Y Health XXXXXX, M.D. OCCURRENCE/TREATMENT *Reviewer’s Comments: As per available medical records, we do not have any evidence to suggest that patient used talcum powder. Medical records prior to 02/18/YYYY are not available to know the abdominal complaints of the patient and its corresponding office visits. Admission for surgical treatment of a probable dysgerminoma: Chief complaint: Patient presents for surgical treatment of a probable dysgerminoma. History of presenting illness: She initially presented to a chiropractor for chronic back pain approximately two months ago and after several weeks of treatment she noted increased abdominal girth and one particular area which was firm and slightly tender in her lower abdomen. Over the last month this mass has become much larger extending to the umbilicus. It is sometimes tender to palpation and does cause her some abdominal pains related to activity and she has noted increased bladder pressure with urgency over the last week or so. *Reviewer’s comment: Corresponding chiropractic records are not available for review to know the diagnosis and treatment rendered for chronic back pain. Preoperative workup showed an elevated Lactate Dehydrogenase (LDH) at 4574 with an Alpha-Fetoprotein (AFP) of less than 30 and a Human Chorionic Gonadotropin (HCG) of less than 10. Chest X-ray and CAT Scan results are not available. *Reviewer’s comment: Corresponding labs reports of LDH, AFP and HCG are not available for review. Physical examination: Abdomen: Soft and nontender except for a mass which extends from the symphysis to the umbilicus. It appears to be somewhat mobile and is mildly tender. Neurological: Cranial nerves II—XII are grossly intact. She is pleasant and cooperative although somewhat anxious about her hospitalization. Deep tendon reflexes and patellar reflexes 4+ with one beat of clonus 4 of 16 PDF REF 8-9, 25-26 Patient Name DATE DOB: 09/17/YYYY PROVIDER OCCURRENCE/TREATMENT PDF REF appreciated. Impression: Patient with probable dysgerminoma, here for surgical treatment. 02/18/YYY XXXXXX Y Health Plan: Bowel prep and preoperative antibiotics and Heparin prophylaxis tonight and she will present to the Operating Room in the morning for unilateral salpingo oophorectomy and possible total abdominal hysterectomy and bilateral salpingo oophorectomy. Labs: Urinalysis: Parameter Results Blood 3+ RBC 8-12 37, 35 CBC: 02/19/YYY XXXXXX Y Health XXXXXX, M.D. Test Result Reference Range WBC 4.46 (Low) 4.5-13.5 x103 RBC 3.78 (Low) 4.2-5.4 x106 HGB 10.5(Low) 12.0-16.0 gm/dL HCT 33 (Low) 37-47% Segmented 63.7 (High) 30-60% neutrophil Operative Report of laparotomy, right oophorectomy, appendectomy, pelvic aortic node sampling and partial omentectomy: Pre and postoperative diagnosis: Germ cell tumor, Ovary Anesthesia: General Procedure performed: Exploratory laparotomy, right oophorectomy, appendectomy, pelvic aortic node sampling and partial omentectomy. Preoperative Problems & Preparations: The patient is a 20-year-old female who gives a history of increased size of the lower abdomen over the past month or so. The patient obviously has a large pelvic tumor extending up to the umbilicus. Just for the record’s sake, the tumor has been virtually asymptomatic except increased size of the lower abdomen with clothes being tight. The patient’s Gynecologist verified this clinically by examination, 5 of 16 10-11 Patient Name DATE PROVIDER DOB: 09/17/YYYY OCCURRENCE/TREATMENT ultrasound and CT scan. *Reviewer’s comment: The corresponding Gynecological visits and the Ultrasound and CT scan reports are not available to note the abdominal symptoms and its findings. After examining the patient, I had a very lengthy discussion with the patient and her family indicating that this is in all probability a germ cell tumor of the ovary and this will be best treated by conservative surgery if at all possible. I explained to the patient that it might be necessary to do a Total Hysterectomy and Bilateral Salpingo-Oophorectomy (THBSO) if we got into bleeding problems and it was unavoidable or if this turned out to another tumor that required this form of therapy. However, in all probability, we would do conservative surgery removing one ovary, sampling lymph nodes and the patient my require chemotherapy. The risk factors concerning this problem have been discussed with the patient and the family and they fully understand them, especially injury to any of the surrounding structures intraoperatively. By that, I mean any structures that surround the uterus or are in close proximity to the uterus or the ovary. Postoperatively, the patient may have fatal embolism, postoperative infection, hemorrhage, bowel obstruction, etc. The patient fully understands this. Description of Procedure: Under general anesthesia, the patient is prepped and draped in the usual sterile manner. Through a low midline incision, the peritoneal cavity was entered. There was only about 10-15 cc of acitic (Must be ascitic) fluid present, but it was aspirated for cytologic purposes. The pathology encountered was a large tumor filling the pelvis and upper and lower abdomen. It extended from the right to the left side. The tumor did originate from the right ovary. There was no recognizable ovarian tissue left. The tumor was approximately 20 cm in greatest diameter. The right tube was normal. There were no adhesions. The tumor had a smooth lobulated surface, dull gray and dull pink in color. The opposite tube and ovary were normal. The uterus was normal in size. Pelvic abdominal exploration was essentially negative, especially the pelvic and aortic node bearing areas. On the right side, the infundibulopelvic ligament was clamped, cut and the pedicle ligated with Chromic 1 catgut and relegated. The remaining connections with the uterus were very easily removed by clamping with a Heaney clamp and excising the tumor. The tumor was sent down to pathology and the path report came back dysgerminoma. With this present, the retroperitoneal space was opened on both sides and pelvic node sampling was carried out involving the iliac vessels, obturator fossa. Small, medium and large 6 of 16 PDF REF Patient Name DATE PROVIDER DOB: 09/17/YYYY OCCURRENCE/TREATMENT hemoclips were used for lymphatic and hemostasis. At the completion of the procedure, the retroperitoneal space was irrigated. The anatomy was found to be intact including the genitofemoral nerve, obturator nerve, large iliac vessels, the ureter. The retroperitoneal space was rinsed and on the right side was drained with a large Hemovac suction and brought out through the right lower quadrant of the abdomen. On the left side, it was extremely dry and it was closed with two or three interrupted Chromic catgut sutures leaving the spaces open so that any drainage could drain into the main peritoneal cavity. This was followed by-an incidental appendectomy. The bowel was packed out of the way and the peritoneum was opened over the bifurcation of the aorta up to the retroperitoneal duodenum. Lymph node sampling was carried out in the aortocaval area removing the fat pad 4x6 cm from the bifurcation to the retroperitoneal duodenum. Small and medium hemoclips were used for lymphatic and hemostasis. The retroperitoneal space was closed over Surgicel using Chromic 00 catgut. PDF REF As I said before, an incidental appendectomy had been carried out. This was followed by a partial omentectomy on a routine basis. Once again, the entire peritoneal cavity was examined and found to be intact. There were no enlarged nodes that could be palpated anywhere in the pelvis or in the aortic area. 02/19/YYY XXXXXX Y Health 02/20/YYY XXXXXX Y Health With hemostasis secured and sponge count reported correct, the peritoneal cavity was rinsed and then closed using Chromic 0 to the peritoneum, Vicryl 1 in the anterior rectus sheath, metal clips in the skin. Postoperative condition is good. Blood loss negligible. The patient goes to the Recovery Room in stable condition. Labs – CBC: Test Result Reference Range RBC 3.32(Low) 4.2-5.4 x106 HGB 9.6 (Low) 12.0-16.0 gm/dL HCT 29.0 (Low) 37-47% Progress note POD#1: (Illegible) Vital signs stable. Temperature 100.6 last evening, now 100. Poor _______effort Complains of itching, does not want Patient Controlled Analgesics (PCA) discontinued Examination: Lungs: Diffused rhonchi Abdomen: Soft, diffuse tenderness and negative bowel sounds Incision clean and dry 7 of 16 35 27 Patient Name DATE PROVIDER DOB: 09/17/YYYY OCCURRENCE/TREATMENT Extremities: No tenderness PDF REF Labs: WBC: 8.45, hemoglobin/ hematocrit 9.6/29.0 Pathology pending 02/20/YYY XXXXXX Y Health 02/20/YYY XXXXXX Y Health Assessment/plan: Stable POD#1 Complains of itching with PCA – Benadryl Increased respiratory effort Increased activity Labs – CBC: Test Result RBC 3.16 (Low) HGB 9.3 (Low) HCT 28.1 (Low) Segmented 63.7 (High) neutrophil Lymphocyte 21.7 (Low) Post operative progress notes: (Illegible) @2045 hrs 35 Reference Range 4.2-5.4 x106 12.0-16.0 gm/dL 37-47% 30-60% 25-50% 28 Regarding: Temperature 101. 4 °F Patient has been febrile all day. As per above poor ___ effort. Patient still on PCA and seems drowsy. May not be breathing deeply secondary to sedation. Has been up in chair thrice today. Not doing well with respirer. Physical examination: Lungs clear to auscultation bilaterally with minimal bibasilar crackles. Cardiovascular regular rhythm with tachycardia. IV sites without erythema. 02/21/YYY XXXXXX Y Health Impression/Plan: POD#0 fever Probable source is respiratory overmedication Will reduce PCA rate to 0.2 every 15 minutes Will increase Albuterol to every 4 hours around the clock Will obtain urinalysis and culture and sensitivity to rule out Urinary Tract Infection (UTI). Discussed with Urogyn doctor Labs – CBC: Test Result 8 of 16 Reference Range 35 Patient Name DATE PROVIDER 02/21/YYY XXXXXX Y Health XXXXXX, M.D. DOB: 09/17/YYYY OCCURRENCE/TREATMENT RBC 3.22 (Low) 4.2-5.4 x106 HGB 9.4 (Low) 12.0-16.0 gm/dL HCT 28.4 (Low) 37-47% Segmented 83.6 (High) 30.60% neutrophil Lymphocyte 10.4 (Low) 25-50% POD#2 Progress note: (Illegible) PDF REF 28 Patient complains of post operative pain and hot. (Ambient temperature in room probably >75°F) Physical examination: Tmax 102.3 Overnight treated with aerosols. Morning labs pending. Temperature now 100.3°F BP 110/54 Input 4200 output 2700 (JVAC 120 cc) Lungs: Few rales in __ no wheezes Heart: Regular Rate and Rhythm (RRR) without murmur Abdomen: Soft, ___ tender, negative bowel sounds Skin: Dry and intact without erythema. Drain site Okay 02/22/YYY XXXXXX Y Health 02/22/YYY XXXXXX Y Health XXXXXX, M.D. Assessment/plan: Post operative fever- if continues today would consider addition of antibiotics for broader spectrum Labs –CBC: 35 Test Result RBC 3.42 (Low) HGB 10.0 (Low) HCT 30.2 (Low) Segmented 83.3 (High) neutrophil Lymphocyte 11.1 (Low) POD#3 Progress note: (Illegible) 29 Reference Range 4.2-5.4 x106 12.0-16.0 gm/dL 37-47% 30.60% 25-50% Patient complains of nausea, emesis x2 yesterday. Positive bowel movements with diet cola. Afebrile. Vital signs stable Abdomen soft and few bowel sounds JVAC patent, 65 cc out in 24 hours Labs: RBC 8.5, Hb 10.0 HCT 30.2 platelets 261 9 of 16 Patient Name DATE DOB: 09/17/YYYY PROVIDER 02/23/YYY XXXXXX Y Health OCCURRENCE/TREATMENT PDF REF Assessment/plan: Nausea may secondary to Demerol Will prescribe per oral analgesia with Phenergan as needed Will give Dulcolax again today Doubt ileus Encourage ambulation Labs: CBC: Test Result Reference Range RBC 2.99 (Low) 4.2-5.4 x106 HGB 8.6(Low) 12.0-16.0 gm/dL HCT 26.3 (Low) 37-47% Segmented 75.7 (High) 30.60% neutrophil Lymphocyte 16.5 (Low) 25-50% 35, 36 Chemistry: 02/23/YYY XXXXXX Y Health XXXXXX, M.D. Test Result Potassium 3.1 (Low) BUN 3 (Low) @0835 hrs 5 BUN/Creatinine ratio @2120 hrs 4 BUN/Creatinine ratio Progress notes POD#4: (Illegible) Reference Range 3.5-5.5 Meq/L 9-18 mg/dL 7-25 7-25 No complaints except labial edema Nausea resolved, Positive flatus Afebrile , vital signs stable Urine culture negative , CBC pending Abdomen soft non tender and normal bowel sounds Skin dry and intact Left labial edema marked No erythema, lesions and drainage Minimally tender JVAC approximately 100 cc over 24 hours Assessment/plan: Doing well Labial edema treated with sitz bath, ice and ambulation No signs and symptoms of hematoma or infection Discontinued IV, Changed to Per oral Keflex with JVAC in 10 of 16 30 Patient Name DATE PROVIDER 02/23/YYY XXXXXX Y Health XXXXXX, M.D. 02/23/YYY XXXXXX Y Health 02/24/YYY XXXXXX Y Health 02/24/YYY XXXXXX Y Health (Signed date) XXXXXX, M.D. DOB: 09/17/YYYY OCCURRENCE/TREATMENT bowel ___ Advance diet X-Ray report of abdomen and PA chest: PDF REF 40 Impression: There is gaseous distention of the small bowel out of proportion to the large bowel and therefore suggestive of a small bowel obstruction. Progress note: @1840 hrs Acute Abdominal Series (AAS) – Suspecting Small Bowel Obstruction (SBO), Marked air fluid levels of small bowel. No air in colon Patient reports nausea with bilious vomiting, Bowel movements X1 today. Small amount of flatus. Abdomen: Not tender non distended minimal (Hypoactive) Bowel sounds 30 Assessment/plan: SBO versus adynamic ileus – No reason for mechanical obstruction. Most likely with operative ileus. Will place Nasogastric. Keep NPO except ice chips. Repeat potassium tonight. Ask surgical Resident to review pulmonary. Labs – Chemistry: 36 Test Potassium Pathology Report: 17,16,15 Result 3.3 (Low) Reference Range 3.5-5.5 Meq/L Collected date: 02/19/YYYY Tissue submitted: Pelvic and aortic node sampling, omental biopsy Frozen section diagnosis: Germ cell tumor, consistent with a dysgerminoma. Gross: The specimens are submitted in nine containers. Container A: This specimen is an ovary, which has been completely replaced by a 17 x 8.5 x 11 cm tumor mass. The capsule of the ovary which is smooth, glistening, grayish white is intact and free of adhesions. Sectioned surfaces of the tumor mass are smooth, soft, and tan pink, with focal areas of hemorrhage and cystic degeneration, but no gross massive necrosis. A fallopian tube is not identified on the external aspect of the ovary. (Multiple sections including sections from the cystic and hemorrhagic areas.) 11 of 16 Patient Name DATE PROVIDER 02/24/YYY XXXXXX Y Health DOB: 09/17/YYYY OCCURRENCE/TREATMENT Container B: Right obturator lymph nodes. Four lymph nodes Container C: Right common iliac lymph node. Two lymph nodes. Container D: The specimen is a 7 cm. vermiform appendix, which is grossly unremarkable on sectioning. (One section). Container E: Omentum biopsy. The specimen consists of an 8.5 x 4 x 2.5 cm. piece of omentum, the sectioned surfaces of which do not show any significant gross lesions. (Random sections). Container F: Right external iliac lymph node. One lymph node. Container G: Left obturator lymph nodes. Three lymph nodes. Container H: Left external iliac lymph nodes. Three lymph nodes. Container I: Aortic lymph nodes. Diagnosis: Specimen A, right ovary, dysgerminoma (pure). Specimens B, C, F, G, H, I, lymph node groups, total of 16 lymph nodes, no evidence of metastatic tumor Specimen D, vermiform appendix, a few peritoneal inclusion cysts, serosal surface of the appendix. Specimen E, omentum, chronic inflammation and mesothelial cell proliferations (no evidence of metastatic tumor) Progress notes POD#5: (Illegible) PDF REF 31 Patient with discomfort secondary to N6; labial edema improved but still with discomfort Physical examination: Tmax 100°F Pulse 100’s otherwise stable vital signs Abdomen: Soft non tender, hyperactive bowel sounds Incision clean and dry intact without erythema. Labial edema decreased 02/25/YYY XXXXXX Y Health Labs reviewed Assessment/plan: POD#5, Patient still with decreased bowel sounds. Plan to continue N6___ Patient appears to be otherwise stable Tachycardia to secondary to decreased Hb. Will follow. May need transfusion if symptomatic Labs: CBC: Test Result Reference Range RBC 3.13 (Low) 4.2-5.4 x106 HGB 8.8 (Low) 12.0-16.0 gm/dL HCT 27.7 (Low) 37-47% 12 of 16 35, 36 Patient Name DATE PROVIDER DOB: 09/17/YYYY OCCURRENCE/TREATMENT Segmented 78.6 (High) 30.60% neutrophil Lymphocyte 13.0 (Low) 25-50% PDF REF Chemistry: 02/25/YYY XXXXXX Y Health Test Result Potassium 3.1 (Low) BUN 3 (Low) BUN/Creatinine ratio 5 (Low) POD#6 Progress note: (Illegible) @0835 hours Reference Range 3.5-5.5 Meq/L 9-18 mg/dL 7-25 32 Patient with discomfort from N6, Otherwise no complaints. Physical examination: Tmax 100.7°F, tachycardia, vital signs otherwise stable. 3900/3730 over 24 hours. N6 ____ guaiac negative Abdomen: Soft, non tender and no bowel sounds noted. No erythema around incision. Incision clean, dry and intact achieved with staples. Labial edema resolved 02/25/YYY XXXXXX Y Health Assessment/plan: Patient remains without bowel sounds – Plan to repeat AAS possibly consult surgery if unchanged from 02/23 Continue N6 suction, patient unchanged from yesterday. JVAC drain discontinued per Dr. XXXX Pathology indicated dysgerminoma without no nodal involvement. Ultrasound of Kidney, Ureter and Bladder (KUB): 41 Impression: The evidence of small bowel obstruction is no longer seen. XXXXX, M.D. 02/26/YYY XXXXXX Y Health 35, 36 Labs: Test RBC HGB HCT MCHC Segmented neutrophil Lymphocyte Result 3.00 (Low) 8.3 (Low) 26.7 (Low) 31.3 (Low) 74.0 (High) Reference Range 4.2-5.4 x106 12.0-16.0 gm/dL 37-47% 32-36 g/dL 30.60% 16.4 (Low) 25-50% Chemistry: 13 of 16 Patient Name DATE PROVIDER 02/26/YYY XXXXXX Y Health DOB: 09/17/YYYY OCCURRENCE/TREATMENT Test Result Reference Range Potassium 3.6 3.5-5.5 Meq/L BUN 3 (Low) 9-18 mg/dL BUN/Creatinine ratio 6 (Low) 7-25 Cardiac enzymes: Test LDH Urine Culture report: Collected date: 02/18/YYYY (Result date taken) 02/26/YYY Y N.XXXXXX, M.D. XXXXXX Health Final: No growth (Result date taken) N.XXXXXX, M.D. Sample: Peritoneal wash 02/26/YYY XXXXXX Y Health Result 305 (High) PDF REF Reference Range 118-242 U/L Extragenital cytology report: Collected date: 02/19/YYYY Final: No malignant cells seen, RBC seen. POD #7 Progress notes: (Illegible) 38 38 32 Patient much improved. N6 discontinued without complaints, positive bowel movements Tmax 100.6°F. vital signs stable. Input/ Output 1800/2000 Incision clean/dry/intact with staples 02/26/YYY XXXXXX Y Health 02/27/YYY XXXXXX Y Health Assessment/plan: Patient stable repeat AAS showed resolution of small bowel obstruction N6 tube discontinued. Diet advanced Remove staples today Progress note: (Illegible) 33 Skin chips out Eating well and had bowel movements Soft and regular diet and have to be followed by Resident in clinic Note: Explained necessity of close follow-up ___ and no more than 85% POD#8 Progress note: (Illegible) 33 No complaints XXXXXX, M.D. Labs: 14 of 16 Patient Name DATE PROVIDER 02/27/YYY XXXXXX Y Health DOB: 09/17/YYYY OCCURRENCE/TREATMENT LDH: 308-decreased from 4574 preop, Hgb 8.3 Assessment/plan: Home with Darvocet, Iron. Instructions given. Follow-up in 4 weeks Discharge Summary: PDF REF 3 Admit date : 02/18/YYYY XXXXXX, M.D. Disposition: Home or self care Final ICD9 diagnoses: Principle: 1830-Malignant neoplasm of ovary Final diagnosis: 2768-Hypopotassemia Final diagnosis: 9974-Gastrointestinal complication, not elsewhere classified Final diagnosis: 5609-Small bowel obstruction 02/27/YYY XXXXXX Y Health Procedure information: Unilateral Oophorectomy Excision or destruction of peritoneal tissue Biopsy of lymphatic structure Incidental appendectomy Final diagnosis: Uterus and adnexa procedures for ovarian or adnexal malignancy. Discharge Instructions: 7 Darvocet N-100 for every 4-6 hours as needed for pain Ferrous Gluconate 300 mg 3x day Colace 100 mg per oral daily No sex, no heavy lifting and shower Follow up: In one month with XXXXXX, M.D. Discharged condition: Discharged to home with family member via wheelchair. 02/18/YYY XXXXXX YHealth 08/29/2016 *Reviewer’s comment: Medical records after 02/27/YYYY are not available to know the condition of the patient post surgical management of ovarian cancer. Hospitalization and other non-related records 15 of 16 59-61, 2, 48, 4, 5-6, 12-14, 1924, 43-46, 47, Patient Name DATE PROVIDER DOB: 09/17/YYYY OCCURRENCE/TREATMENT PDF REF 62-63, 64, 65, 66-68, 88-89, 90-91, 94-95, 97-98, 42, 1, 96, 69-87, 99-156, 49-58, 92-93 16 of 16