Download Borrelia burgdorferi

By: Matt Hryniewicki
Classification
 Domain: Bacteria
 Kingdom: Bacteria
 Phylum: Spirochaetes
 Order: Spirochaetales
 Family: Spirochaetaceae
 Genus: Borrelia
 Species: B. burgdorferi
Structure
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Helical Shape
Contains inner and outer cell membrane
Flexible cell wall
The cell’s flagella are located inside the
periplasm between the inner and outer
cell membranes (endoflagella)
 Allows cell to travel through highly viscous
fluids and materials

Highly invasive
 Outer surface proteins
 Can turn into a cyst if in unfavorable
conditions
 Converts back to spirochete under
favorable conditions
Metabolism
 Relies on host for energy precursors
 Limited metabolic capabilities
 Contains many transport proteins that are used to
obtain compounds from host serum or environment
 Uses carbohydrates as source of energy in mammals
 Uses N-acetylglucosamine as a major source of energy
in ticks.
 Produces ATP solely by using substrate-level
phophorylation
Nutrition
 Can be cultivated in vitro
 Growth medium contains over 13 ingredients in a rabbit
serum base
 Optimal temperature is 32 degrees Celsius
 Microaerophile or anaerobic
Gram Stain
 Negative gram stain
History
 First recorded in 1883 by Alfred Buchwald
 Discovered in 1982 by Dr. Willy Burgdorfer
 Several cases popped up in the towns of Lyme and Old
Lyme in 1975
Disease Causing
 Causes Lyme Disease
 Carried by ticks

Ticks pick up the bacteria from infected
mice and deer
 Produces a “bulls-eye” rash
 Treated with antibiotics if predicted
within 72 hours
 Ibuprofen used to relieve joint
stiffness
 Most prevalent tick-borne illness in
the U.S.
Works Cited
 Abedon, Stephen T. "Bacteria Binomials." Ohio State Mansfield. 26 Apr. 1998.
Web. 03 Feb. 2011. <http://mansfield.osu.edu/~sabedon/biol4045.htm>.
 "Borrelia Burgdorferi - MicrobeWiki." MicrobeWiki - MicrobeWiki. Ed. Dan
Holligan. Web. 03 Feb. 2011.
<http://microbewiki.kenyon.edu/index.php?title=Borrelia_burgdorferi&
redirect=no>.
 "Borrelia Burgdorferi." RIT - People - Home. Web. 03 Feb. 2011.
<http://people.rit.edu/mrppph/animals/pages/borrelia
burgdorferi.htm>.
 "Classification." BioWeb Home. Web. 03 Feb. 2011.
<http://bioweb.uwlax.edu/bio203/s2007/joyce_kait/classification.htm>.
 "Disease Carriers." Wadsworth Center. New York State Department of Health.
Web. 3
Feb. 2011.
 "Influenza." Medical Ecology @ Www.MedicalEcology.org. Web. 03 Feb. 2011.
<http://www.medicalecology.org/diseases/lyme/lyme_disease.htm>.
 "Lyme Disease Crash Course--Everything You Need to Know in 5 Mins. |
Facebook." Welcome to Facebook - Log In, Sign Up or Learn More. Web.
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03 Feb. 2011.
<http://www.facebook.com/note.php?note_id=25754076527>.
"Lyme Disease." Our Politics: Changing the Way Politics Works One Blog Post
at a Time. | Just Another WordPress Site. Web. 03 Feb. 2011.
<http://www.ourpoliticsblog.com/huhu/lyme-disease.html>.
"Lyme Disease." Wikipedia, the Free Encyclopedia. Web. 03 Feb. 2011.
<http://en.wikipedia.org/wiki/Lyme_disease>.
"Microbial Spore Formation." MicrobeWorld. 14 Jan. 2009. Web. 03 Feb. 2011.
<http://www.microbeworld.org/index.php?option=com_content&view=
article&id=160&Itemid=84>.
Newsfox - Daily News and Press Releases. Web. 03 Feb. 2011.
<http://www.newsfox.com/show_attach.mc?pte=080930034>.
"PubMed Health - Lyme Disease." NCBI. 23 Feb. 2010. Web. 03 Feb. 2011.
<http://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0002296>.
Todar, Kenneth. "Lyme Disease." Online Textbook of Bacteriology. 2011. Web. 03
Feb. 2011. <http://www.textbookofbacteriology.net/Lyme.html>.
"Viewing the Arrangement of Borrelia Burgdorferi Flagella by Electron
Cryotomography." Spirochetes Unwound. Web. 03 Feb. 2011.
<http://spirochetesunwound.blogspot.com/2009/02/viewingarrangement-of-borrelia.html>.
Web. 03 Feb. 2011. <http://www.ncbi.nlm.nih.gov/pubmed/12422604>.