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Commonly Abused Drugs
Most drugs of abuse can alter a person's thinking and judgment, leading to health risks, including addiction, drugged
driving, and infectious disease. Most drugs could potentially harm an unborn baby; pregnancy-related issues are listed in
the chart below for drugs where there is enough scientific evidence to connect the drug use to specific negative effects.
For information about treatment options for drug addiction, see NIDA’s Treatment pages . For drug use trends,
see our Trends and Statistics page.
The following drugs are included in this resource:
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 Methamphetamine
 Over-the-counter Cough/Cold Medicines
(Dextromethorphan or DXM)
 PCP
 Prescription Opioids
 Prescription Sedatives (Tranquilizers, Depressants)
 Prescription Stimulants
 Psilocybin
 Rohypnol® (Flunitrazepam)
 Salvia
 Steroids (Anabolic)
 Synthetic Cannabinoids
 Synthetic Cathinones ("Bath Salts")
 Tobacco
Alcohol
Ayahuasca
Cocaine
DMT
GHB
Hallucinogens
Heroin
Inhalants
Ketamine
Khat
Kratom
LSD
Marijuana (Cannabis)
MDMA (Ecstasy/Molly)
Mescaline (Peyote)
**
The Drug Enforcement Agency (DEA) schedule indicates the drug’s acceptable medical use and its potential for abuse
or dependence. More information can be found on the DEA website.
Alcohol
People drink to socialize, celebrate, and relax. Alcohol often has a strong effect on people—and throughout
history, people have struggled to understand and manage alcohol’s power. Why does alcohol cause people to act and
feel differently? How much is too much? Why do some people become addicted while others do not? The National
Institute on Alcohol Abuse and Alcoholism is researching the answers to these and many other questions about alcohol.
Here’s what is known:
Alcohol’s effects vary from person to person, depending on a variety of factors, including:
 How much you drink
 Your health status
 How often you drink
 Your family history
 Your age
While drinking alcohol is itself not necessarily a problem—drinking too much can cause a range of consequences, and
increase your risk for a variety of problems. For more information on alcohol’s effects on the body, please see
the National Institute on Alcohol Abuse and Alcoholism ’s related web page describing alcohol’s effects on the
body .
Ayahuasca
A hallucinogenic tea made in the Amazon from a DMT-containing plant (Psychotria viridis or Diplopterys cabrerana or
other) along with another vine (Banisteriopsis caapi) that contains an MAO Inhibitor preventing the natural
breakdown of DMT in the digestive system, thereby facilitating a prolonged hallucinatory experience. It was used
historically in Amazonian religious and healing rituals and is increasingly used by tourists. For more information, see
the Hallucinogens and Dissociative Drugs Research Report.
Street Names
Aya, Yagé, Hoasca
Commercial Names
Common Forms
No commercial uses
Brewed as tea
Common Ways Taken
Swallowed as tea
DEA
Schedule
DMT is
Schedule I,
but plants
containing
it are not
controlled
Possible Health Effects
Short-term
Strong hallucinations including perceptions of otherworldly imagery, altered visual and
auditory perceptions; increased blood pressure; vomiting.
Long-term
Unknown.
Other Health-related
Issues
Unknown.
In Combination with
Alcohol
Unknown.
Withdrawal
Symptoms
Unknown.
Treatment Options
Medications
It is not known whether ayahuasca is addictive. There are no FDA-approved medications to
treat addiction to ayahuasca or other hallucinogens.
Behavioral Therapies
More research is needed to find out if ayahuasca is addictive and, if so, whether behavioral
therapies are effective.
Cocaine
A powerfully addictive stimulant drug made from the leaves of the coca plant native to South America. For more
information, see the Cocaine Research Report.
Street Names
Commercial Names
Blow, Bump, C, Candy,
Charlie, Coke, Crack,
Flake, Rock, Snow,
Toot
Cocaine hydrochloride
topical solution
(anesthetic rarely used
in medical procedures)
Common Forms
White powder, whitish rock
crystal
Common Ways
Taken
Snorted, smoked,
injected
DEA
Schedule
II
Possible Health Effects
Short-term
Narrowed blood vessels; enlarged pupils; increased body temperature, heart rate, and blood
pressure; headache; abdominal pain and nausea; euphoria; increased energy, alertness;
insomnia, restlessness; anxiety; erratic and violent behavior, panic attacks, paranoia,
psychosis; heart rhythm problems, heart attack; stroke, seizure, coma.
Long-term
Loss of sense of smell, nosebleeds, nasal damage and trouble swallowing from snorting;
infection and death of bowel tissue from decreased blood flow; poor nutrition and weight
loss from decreased appetite.
Other Health-related
Issues
Pregnancy: premature delivery, low birth weight, neonatal abstinence syndrome.
Risk of HIV, hepatitis, and other infectious diseases from shared needles.
In Combination with
Alcohol
Greater risk of overdose and sudden death than from either drug alone.
Withdrawal
Symptoms
Depression, tiredness, increased appetite, insomnia, vivid unpleasant dreams, slowed
thinking and movement, restlessness.
Treatment Options
Medications
Behavioral Therapies
There are no FDA-approved medications to treat cocaine addiction.
•
•
•
•
•
Cognitive-behavioral therapy (CBT)
Community reinforcement approach plus vouchers
Contingency management, or motivational incentives
The matrix model
12-Step facilitation therapy
DMT
A synthetic drug producing intense but relatively short-lived hallucinogenic experiences; also naturally occurring in
some South American plants (See Ayahuasca). For more information, see the Hallucinogens and Dissociative Drugs
Research Report.
Street Names
DMT, Dimitri
Commercial Names
No commercial uses
Common Forms
White or yellow
crystalline powder
Common Ways Taken
DEA
Schedule
Smoked, injected
I
Possible Health Effects
Short-term
Intense visual hallucinations, depersonalization, auditory distortions, and an altered
perception of time and body image, usually resolving in 30-45 minutes or less. Physical
effects include hypertension, increased heart rate, agitation, seizures, dilated pupils,
involuntary rapid eye movements, dizziness, incoordination.
Long-term
Unknown
Other Health-related
Issues
At high doses, coma and respiratory arrest have occurred.
In Combination with
Alcohol
Unknown.
Withdrawal
Symptoms
Unknown.
Treatment Options
Medications
It is not known whether DMT is addictive. There are no FDA-approved medications to treat
addiction to DMT or other hallucinogens.
Behavioral Therapies
More research is needed to find out if DMT is addictive and, if so, whether behavioral
therapies are effective.
GHB
A depressant approved for use in the treatment of narcolepsy, a disorder that causes daytime "sleep attacks."
Street Names
Commercial Names
Common Forms
Common
DEA
Schedule
Ways
G, Georgia Home Boy, GammaColorless liquid, white
Swallowed (often
I
Goop, Grievous Bodily hydroxybutyrate
powder
combined with
Harm, Liquid Ecstasy,
or sodium oxybate
alcohol or
Liquid X, Soap, Scoop
(Xyrem®)
other
Possible Health
Euphoria, drowsiness, decreased anxiety, confusion, memory loss, hallucinations, excited
Short-term
and aggressive behavior, nausea, vomiting, unconsciousness, seizures, slowed heart rate
and
Long-term
Unknown.
Other Health-related Sometimes used as a date rape drug.
Issues
In Combination with
Nausea, problems with breathing, greatly increased depressant effects.
Alcohol
Withdrawal
Insomnia, anxiety, tremors, sweating, increased heart rate and blood pressure, psychotic
Symptoms
thoughts.
Treatment
Medications
Benzodiazepines
Behavioral Therapies More research is needed to find out if behavioral therapies can be used to treat GHB
addiction.
Hallucinogens
Drugs that cause profound distortions in a person’s perceptions of reality, such as ketamine, LSD, mescaline
(peyote), PCP, psilocybin, salvia, DMT, and ayahuasca. For more information, see the Hallucinogens and
Dissociative Drugs Research Report.
Heroin
An opioid drug made from morphine, a natural substance extracted from the seed pod of the Asian opium poppy
plant. For more information, see the Heroin Research Report.
Street Names
Brown sugar, China
White, Dope, H, Horse,
Junk, Skag, Skunk,
Smack, White Horse
With OTC cold
medicine and
antihistamine: Cheese
Commercial Names
No commercial uses
Common Forms
White or brownish
powder, or black sticky
substance known as
"black tar heroin"
Common Ways Taken
Injected, smoked,
snorted
DEA
Schedule
I
Possible Health Effects
Short-term
Euphoria; warm flushing of skin; dry mouth; heavy feeling in the hands and feet; clouded
thinking; alternate wakeful and drowsy states; itching; nausea; vomiting; slowed breathing
and heart rate.
Long-term
Collapsed veins; abscesses (swollen tissue with pus); infection of the lining and valves in the
heart; constipation and stomach cramps; liver or kidney disease; pneumonia.
Other Health-related
Issues
Pregnancy: miscarriage, low birth weight, neonatal abstinence syndrome.
Risk of HIV, hepatitis, and other infectious diseases from shared needles.
In Combination with
Alcohol
Dangerous slowdown of heart rate and breathing, coma, death.
Withdrawal
Symptoms
Restlessness, muscle and bone pain, insomnia, diarrhea, vomiting, cold flashes with goose
bumps ("cold turkey"), leg movements.
Treatment Options
Medications
•
•
•
Behavioral Therapies
•
•
Methadone
Buprenorphine
Naltrexone (short- and long-acting forms)
Contingency management, or motivational incentives
12-Step facilitation therapy
Inhalants
Solvents, aerosols, and gases found in household products such as spray paints, markers, glues, and cleaning fluids;
also nitrites (e.g., amyl nitrite), which are prescription medications for chest pain. For more information, see the
Inhalants Research Report.
Street Names
Poppers, snappers,
whippets, laughing gas
Commercial Names
Various
Common Forms
Paint thinners or removers,
degreasers, dry-cleaning
fluids, gasoline, lighter fluids,
correction fluids, permanent
markers, electronics cleaners
and freeze sprays, glue, spray
paint, hair or deodorant
sprays, fabric protector
sprays, aerosol computer
cleaning products, vegetable
oil sprays, butane lighters,
propane tanks, whipped
cream aerosol containers,
refrigerant gases, ether,
chloroform, halothane,
nitrous oxide
Common Ways
Taken
Inhaled through the
nose or mouth
DEA
Schedule
Not
scheduled
Possible Health Effects
Short-term
Confusion; nausea; slurred speech; lack of coordination; euphoria; dizziness; drowsiness;
disinhibition, lightheadedness, hallucinations/delusions; headaches; sudden sniffing death
due to heart failure (from butane, propane, and other chemicals in aerosols); death from
asphyxiation, suffocation, convulsions or seizures, coma, or choking.
Nitrites: enlarged blood vessels, enhanced sexual pleasure, increased heart rate, brief
sensation of heat and excitement, dizziness, headache.
Long-term
Liver and kidney damage; bone marrow damage; limb spasms due to nerve damage; brain
damage from lack of oxygen that can cause problems with thinking, movement, vision, and
hearing.
Nitrites: increased risk of pneumonia.
Other Health-related
Issues
Pregnancy: low birth weight, bone problems, delayed behavioral development due to brain
problems, altered metabolism and body composition.
In Combination with
Alcohol
Nitrites: dangerously low blood pressure.
Withdrawal
Symptoms
Nausea, loss of appetite, sweating, tics, problems sleeping, and mood changes.
Medications
Behavioral Therapies
Treatment Options
There are no FDA-approved medications to treat inhalant addiction.
More research is needed to find out if behavioral therapies can be used to treat inhalant
addiction.
Ketamine
A dissociative drug used as an anesthetic in veterinary practice. Dissociative drugs are hallucinogens that cause the
user to feel detached from reality. For more information, see the Hallucinogens and Dissociative Drugs
Research Report.
Street Names
Cat Valium, K, Special
K, Vitamin K
Short-term
Long-term
Commercial Names
Ketalar®
Common Forms
Liquid, white powder
Common Ways Taken
DEA
Schedule
Injected, snorted,
smoked (powder
added to tobacco or
marijuana cigarettes),
swallowed
III
Possible Health Effects
Problems with attention, learning, and memory; dreamlike states, hallucinations; sedation;
confusion and problems speaking; loss of memory; problems moving, to the point of being
immobile; raised blood pressure; unconsciousness; slowed breathing that can lead to
d
h and pain in the bladder; kidney problems; stomach pain; depression; poor memory.
Ulcers
Other Health-related
Issues
In Combination with
Alcohol
Sometimes used as a date rape drug.
Risk of HIV, hepatitis, and other infectious diseases from shared needles.
Increased risk of adverse effects.
Withdrawal Symptoms
Unknown.
Treatment Options
Medications
There are no FDA-approved medications to treat addiction to ketamine or other dissociative
drugs.
Behavioral Therapies
More research is needed to find out if behavioral therapies can be used to treat addiction to
dissociative drugs.
Khat
Pronounced "cot," a shrub (Catha edulis) found in East Africa and southern Arabia; contains the psychoactive
chemicals cathinone and cathine. People from African and Arabian regions (up to an estimated 20 million worldwide)
have used khat for centuries as part of cultural tradition and for its stimulant-like effects.
Street Names
Commercial Names
Common Forms
Abyssinian Tea, African
Salad, Catha, Chat, Kat,
Oat
No commercial uses
Fresh or dried leaves
Common Ways
Taken
Chewed, brewed
as tea
DEA
Schedule
Cathinone is
a Schedule I
drug, making
khat use
illegal, but
the khat
plant is not
controlled
Possible Health Effects
Short-term
Euphoria, increased alertness and arousal, increased blood pressure and heart rate,
depression, inability to concentrate, irritability, loss of appetite, insomnia.
Long-term
Tooth decay and gum disease; gastrointestinal disorders such as constipation, ulcers,
stomach inflammation, and increased risk of upper gastrointestinal tumors; cardiovascular
disorders such as irregular heartbeat, decreased blood flow, and heart attack.
Other Health-related
Issues
In rare cases associated with heavy use: psychotic reactions such as fear, anxiety, grandiose
delusions (fantastical beliefs that one has superior qualities such as fame, power, and
wealth), hallucinations, and paranoia.
In Combination with
Alcohol
Withdrawal
Symptoms
Unknown.
Medications
It is not known whether khat is addictive. There are no FDA-approved medications to treat
addiction to khat.
Behavioral Therapies
More research is needed to find out if khat is addictive and, if so, whether behavioral
therapies are effective.
Depression, nightmares, trembling, and lack of energy.
Treatment Options
Kratom
A tropical deciduous tree (Mitragyna speciosa) native to Southeast Asia, with leaves that contain mitragynine, a
psychoactive (mind-altering) opioid. Kratom is consumed for mood-lifting effects and pain relief and as an
aphrodisiac. For more information, see the Kratom DrugFacts.
Street Names
Commercial Names
Herbal Speedball, Biak-biak,
Ketum, Kahuam, Ithang,
Thom
None
Common Forms
Common Ways Taken
DEA
Schedule
Fresh or dried leaves,
powder, liquid, gum
Chewed (whole leaves);
eaten (mixed in food or
brewed as tea);
occasionally smoked
Not
scheduled
Possible Health Effects
Short-term
Sensitivity to sunburn, nausea, itching, sweating, dry mouth, constipation, increased
urination, loss of appetite.
Low doses: increased energy, sociability, alertness.
High doses: sedation, euphoria, decreased pain.
Long-term
Anorexia, weight loss, insomnia, skin darkening, dry mouth, frequent urination, constipation.
Hallucination and paranoia with long-term use at high doses.
Other Health-related
Issues
In Combination with
Alcohol
Withdrawal
Symptoms
Unknown.
Unknown.
Muscle aches, insomnia, irritability, hostility, aggression, emotional changes, runny nose,
jerky movements.
Treatment Options
Medications
No clinical trials have been conducted on medications for kratom addiction.
Behavioral Therapies
More research is needed to find out if behavioral therapies can be used to treat addiction to
kratom.
LSD
A hallucinogen manufactured from lysergic acid, which is found in ergot, a fungus that grows on rye and other grains.
LSD is an abbreviation of the scientific name lysergic acid diethylamide. For more information, see the Hallucinogens
and Dissociative Drugs Research Report.
Street Names
Commercial Names
Acid, Blotter, Blue
Heaven, Cubes,
Microdot, Yellow
Sunshine
No commercial uses
Common Forms
Tablet; capsule; clear liquid;
small, decorated squares of
absorbent paper that liquid
has been added to
Common Ways
Taken
DEA
Schedule
Swallowed, absorbed
through mouth
tissues (paper
squares)
I
Short-term
Possible Health Effects
Rapid emotional swings; distortion of a person’s ability to recognize reality, think rationally,
or communicate with others; raised blood pressure, heart rate, body temperature; dizziness
and insomnia; loss of appetite; dry mouth; sweating; numbness; weakness; tremors;
enlarged pupils.
Long-term
Frightening flashbacks (called Hallucinogen Persisting Perception Disorder [HPPD]); ongoing
visual disturbances, disorganized thinking, paranoia, and mood swings.
Other Health-related
Issues
In Combination with
Alcohol
Unknown.
Withdrawal
Symptoms
Unknown.
Medications
Behavioral Therapies
May decrease the perceived effects of alcohol.
Treatment Options
There are no FDA-approved medications to treat addiction to LSD or other hallucinogens.
More research is needed to find out if behavioral therapies can be used to treat addiction to
hallucinogens.
Marijuana (Cannabis)
Marijuana is made from the hemp plant, Cannabis sativa. The main psychoactive (mind-altering) chemical in
marijuana is delta-9-tetrahydrocannabinol, or THC. For more information, see the Marijuana Research Report.
Street Names
Commercial Names
Common Forms
Common Ways Taken
Blunt, Bud, Dope,
Ganja, Grass, Green,
Herb, Joint, Mary
Jane, Pot, Reefer,
Sinsemilla, Skunk,
Smoke, Trees, Weed;
Hashish: Boom,
Gangster, Hash, Hemp
Various brand names in
states where the sale
of marijuana is legal
Greenish-gray mixture of
dried, shredded leaves,
stems, seeds, and/or
flowers; resin (hashish) or
sticky, black liquid (hash
oil)
Smoked, eaten (mixed in
food or brewed as tea)
DEA
Schedule
I
Short-term
Possible Health Effects
Enhanced sensory perception and euphoria followed by drowsiness/relaxation; slowed
reaction time; problems with balance and coordination; increased heart rate and appetite;
problems with learning and memory; hallucinations; anxiety; panic attacks; psychosis.
Long-term
Mental health problems, chronic cough, frequent respiratory infections.
Other Health-related
Issues
Youth: possible loss of IQ points when repeated use begins in adolescence.
Pregnancy: babies born with problems with attention, memory, and problem solving.
In Combination with
Alcohol
Increased heart rate, blood pressure; further slowing of mental processing and reaction
time.
Withdrawal
Symptoms
Irritability, trouble sleeping, decreased appetite, anxiety.
Treatment Options
Medications
Behavioral Therapies
There are no FDA-approved medications to treat marijuana addiction.
•
•
•
•
Cognitive-behavioral therapy (CBT)
Contingency management, or motivational incentives
Motivational Enhancement Therapy (MET)
Behavioral treatments geared to adolescents
MDMA (Ecstasy/Molly)
A synthetic, psychoactive drug that has similarities to both the stimulant amphetamine and the hallucinogen
mescaline. MDMA is an abbreviation of the scientific name 3,4-methylenedioxy-methamphetamine. For more
information, see the MDMA (Ecstasy) Abuse Research Report.
Street Names
Adam, Clarity, Eve,
Lover's Speed, Peace,
Uppers
Short-term
Commercial Names
No commercial uses
Common Forms
Colorful tablets with
imprinted logos,
capsules, powder, liquid
Common Ways Taken
DEA
Schedule
Swallowed, snorted
I
Possible Health Effects
Lowered inhibition; enhanced sensory perception; confusion; depression; sleep problems;
anxiety; increased heart rate and blood pressure; muscle tension; teeth clenching; nausea;
blurred vision; faintness; chills or sweating; sharp rise in body temperature leading to liver,
kidney, or heart failure and death.
Long-term
Long-lasting confusion, depression, problems with attention, memory, and sleep; increased
anxiety, impulsiveness, aggression; loss of appetite; less interest in sex.
Other Health-related
Issues
In Combination with
Alcohol
Withdrawal
Symptoms
Unknown.
Medications
Behavioral Therapies
May increase the risk of cell and organ damage.
Fatigue, loss of appetite, depression, trouble concentrating.
Treatment Options
There is conflicting evidence about whether MDMA is addictive. There are no FDA-approved
medications to treat MDMA addiction.
More research is needed to find out if behavioral therapies can be used to treat MDMA
addiction.
Mescaline (Peyote)
A hallucinogen found in disk-shaped "buttons" in the crown of several cacti, including peyote. For more information,
see the Hallucinogens and Dissociative Drugs Research Report.
Street Names
Buttons, Cactus, Mesc
Commercial Names
No commercial uses
Common Forms
Fresh or dried buttons,
capsule
Common Ways
Taken
Swallowed (chewed
or soaked in water
and drunk)
Possible Health Effects
Short-term
Enhanced perception and feeling; hallucinations; euphoria; anxiety; increased body
temperature, heart rate, blood pressure; sweating; problems with movement.
Long-term
Unknown.
Other Health-related
Issues
Unknown.
In Combination with
Alcohol
Unknown.
Withdrawal
Symptoms
Unknown.
DEA
Schedule
I
Treatment Options
Medications
There are no FDA-approved medications to treat addiction to mescaline or other
hallucinogens.
Behavioral Therapies
More research is needed to find out if behavioral therapies can be used to treat addiction to
hallucinogens.
Methamphetamine
An extremely addictive stimulant amphetamine drug. For more information, see the Methamphetamine Research
Report.
Street Names
Crank, Chalk, Crystal,
Fire, Glass, Go Fast,
Ice, Meth, Speed
Commercial Names
Desoxyn®
Common Forms
White powder or pill;
crystal meth looks like
pieces of glass or shiny
blue-white "rocks" of
different sizes
Common Ways Taken
DEA
Schedule
Swallowed, snorted,
smoked, injected
II
Possible Health Effects
Short-term
Increased wakefulness and physical activity; decreased appetite; increased breathing, heart
rate, blood pressure, temperature; irregular heartbeat.
Long-term
Anxiety, confusion, insomnia, mood problems, violent behavior, paranoia, hallucinations,
delusions, weight loss, severe dental problems ("meth mouth"), intense itching leading to
skin sores from scratching.
Other Health-related
Issues
Pregnancy: premature delivery; separation of the placenta from the uterus; low birth
weight; lethargy; heart and brain problems.
Risk of HIV, hepatitis, and other infectious diseases from shared needles.
In Combination with
Alcohol
Masks the depressant effect of alcohol, increasing risk of alcohol overdose; may increase
blood pressure and jitters.
Withdrawal
Symptoms
Depression, anxiety, tiredness.
Treatment Options
Medications
Behavioral Therapies
There are no FDA-approved medications to treat methamphetamine addiction.
•
•
•
•
Cognitive-behavioral therapy (CBT)
Contingency management or motivational incentives
The matrix model
12-Step facilitation therapy
Over-the-counter Cough/Cold Medicines (Dextromethorphan or DXM)
Psychoactive when taken in higher-than-recommended amounts. For more information, see the Cough and Cold
Medicine Abuse DrugFacts.
Street Names
Robotripping, Robo,
Triple C
Commercial Names
Various (many brand
names include "DM")
Common Forms
Syrup, capsule
Common Ways Taken
Swallowed
DEA
Schedule
Not
scheduled
Possible Health Effects
Short-term
Euphoria; slurred speech; increased heart rate, blood pressure, temperature; numbness;
dizziness; nausea; vomiting; confusion; paranoia; altered visual perceptions; problems with
movement; buildup of excess acid in body fluids.
Long-term
Unknown.
Other Health-related
Issues
Breathing problems, seizures, and increased heart rate may occur from other ingredients in
cough/cold medicines.
In Combination with
Alcohol
Increased risk of adverse effects.
Withdrawal
Symptoms
Unknown.
Treatment Options
Medications
There are no FDA-approved medications to treat addiction to over-the-counter cough/cold
medicines.
Behavioral Therapies
More research is needed to find out if behavioral therapies can be used to treat addiction to
over-the-counter cough/cold medicines.
PCP
A dissociative drug developed as an intravenous anesthetic that has been discontinued due to serious adverse effects.
Dissociative drugs are hallucinogens that cause the user to feel detached from reality. PCP is an abbreviation of the
scientific name, phencyclidine. For more information, see the Hallucinogens and Dissociative Drugs Research Report.
Street Names
Angel Dust, Boat, Hog,
Love Boat, Peace Pill
Commercial Names
No commercial uses
Common Forms
White or colored powder,
tablet, or capsule; clear liquid
Common Ways
Taken
Injected, snorted,
swallowed, smoked
(powder added to
mint, parsley,
oregano, or
marijuana)
DEA
Schedule
I, II
Possible Health Effects
Short-term
Delusions, hallucinations, paranoia, problems thinking, a sense of distance from one’s
environment, anxiety.
Low doses: slight increase in breathing rate; increased blood pressure and heart rate;
shallow breathing; face redness and sweating; numbness of the hands or feet; problems
with movement.
High doses: lowered blood pressure, pulse rate, breathing rate; nausea; vomiting; blurred
vision; flicking up and down of the eyes; drooling; loss of balance; dizziness; violence;
suicidal thoughts; seizures, coma, and death.
Long-term
Memory loss, problems with speech and thinking, depression, weight loss, anxiety.
Other Health-related
Issues
PCP has been linked to self-injury.
Risk of HIV, hepatitis, and other infectious diseases from shared needles.
In Combination with
Alcohol
Increased risk of coma.
Withdrawal
Symptoms
Headaches, sweating.
Treatment Options
Medications
There are no FDA-approved medications to treat addiction to PCP or other dissociative
drugs.
Behavioral Therapies
More research is needed to find out if behavioral therapies can be used to treat addiction to
dissociative drugs.
Prescription Opioids
Pain relievers with an origin similar to that of heroin. Opioids can cause euphoria and are often used nonmedically,
leading to overdose deaths. For more information, see the Prescription Drug Abuse Research Report.
Street Names
Commercial Names
(Common)
Common Forms
Common Ways Taken
Captain Cody, Cody,
Lean, Schoolboy,
Sizzurp, Purple Drank
With glutethimide:
Doors & Fours, Loads,
Pancakes and Syrup
DEA
Schedule
Codeine (various brand
names)
Tablet, capsule, liquid
Injected, swallowed
(often mixed with soda
and flavorings)
Apache, China Girl,
China White, Dance
Fever, Friend,
Goodfella, Jackpot,
Murder 8, Tango and
Cash, TNT
Fentanyl (Actiq®,
Duragesic®,
Sublimaze®)
Lozenge, sublingual
tablet, film, buccal tablet
Injected, smoked,
snorted
II
Vike, Watson-387
Hydrocodone or
dihydrocodeinone
(Vicodin®, Lortab®,
Lorcet®, and others)
Capsule, liquid, tablet
Swallowed, snorted,
injected
II
II, III, V
D, Dillies, Footballs,
Juice, Smack
Hydromorphone
(Dilaudid®)
Liquid, suppository
Injected, rectal
II
Demmies, Pain Killer
Meperidine (Demerol®)
Tablet, liquid
Swallowed, snorted,
injected
II
Amidone, Fizzies
With MDMA:
Chocolate Chip
Cookies
Methadone
(Dolophine®,
Methadose®)
Tablet, dispersible tablet,
liquid
Swallowed, injected
II
M, Miss Emma,
Monkey, White Stuff
Morphine
(Duramorph®,
Roxanol®)
Tablet, liquid, capsule,
suppository
Injected, swallowed,
smoked
II, III
O.C., Oxycet,
Oxycotton, Oxy,
Hillbilly Heroin, Percs
Oxycodone
(OxyContin®,
Percodan®, Percocet®,
and others)
Capsule, liquid, tablet
Swallowed, snorted,
injected
II
Biscuits, Blue Heaven,
Blues, Mrs. O, O
Bomb, Octagons, Stop
Signs
Oxymorphone
(Opana®)
Tablet
Swallowed, snorted,
injected
II
Possible Health Effects
Short-term
Pain relief, drowsiness, nausea, constipation, euphoria, confusion, slowed breathing, death.
Long-term
Unknown.
Other Health-related
Issues
Pregnancy: Miscarriage, low birth weight, neonatal abstinence syndrome.
Older adults: higher risk of accidental misuse or abuse because many older adults have multiple
prescriptions, increasing the risk of drug-drug interactions, and breakdown of drugs slows with
age; also, many older adults are treated with prescription medications for pain.
Risk of HIV, hepatitis, and other infectious diseases from shared needles.
In Combination with
Alcohol
Dangerous slowing of heart rate and breathing leading to coma or death.
Withdrawal
Symptoms
Restlessness, muscle and bone pain, insomnia, diarrhea, vomiting, cold flashes with goose
bumps ("cold turkey"), leg movements.
Treatment Options
Medications
•
•
•
Behavioral Therapies
Methadone
Buprenorphine
Naltrexone (short- and long-acting)
Behavioral therapies that have helped treat addiction to heroin may be useful in treating
prescription opioid addiction.
Prescription Sedatives (Tranquilizers, Depressants)
Medications that slow brain activity, which makes them useful for treating anxiety and sleep problems. For more
information, see the Prescription Drug Abuse Research Report.
Street Names
Barbs, Phennies, Red
Birds, Reds, Tooies,
Yellow Jackets,
Yellows
Candy, Downers,
Sleeping Pills, Tranks
Forget-me Pill,
Mexican Valium, R2,
Roche, Roofies,
Roofinol, Rope,
Rophies
Commercial Names
(Common)
Barbiturates:
pentobarbital
(Nembutal®),
phenobarbital
(Luminal®)
Benzodiazepines:
alprazolam (Xanax®),
chlorodiazepoxide
(Limbitrol®), diazepam
(Valium®), lorazepam
(Ativan®), triazolam
(Halicon®)
Sleep Medications:
eszopiclone (Lunesta®),
zaleplon (Sonata®),
zolpidem (Ambien®)
Common Forms
Common Ways Taken
Pill, capsule, liquid
Swallowed, injected
DEA
Schedule
II, III, IV
Pill, capsule, liquid
Swallowed, snorted
IV
Pill, capsule, liquid
Swallowed, snorted
IV
Short-term
Possible Health Effects
Drowsiness, slurred speech, poor concentration, confusion, dizziness, problems with
movement and memory, lowered blood pressure, slowed breathing.
Long-term
Unknown.
Other Health-related
Issues
In Combination with
Alcohol
Sleep medications are sometimes used as date rape drugs.
Risk of HIV, hepatitis, and other infectious diseases from shared needles.
Further slows heart rate and breathing, which can lead to death.
Withdrawal
Symptoms
Must be discussed with a health care provider; barbiturate withdrawal can cause a serious
abstinence syndrome that may even include seizures.
Medications
Treatment Options
There are no FDA-approved medications to treat addiction to prescription sedatives;
lowering the dose over time must be done with the help of a health care provider.
Behavioral Therapies
More research is needed to find out if behavioral therapies can be used to treat addiction to
prescription sedatives.
Prescription Stimulants
Medications that increase alertness, attention, energy, blood pressure, heart rate, and breathing rate. For more
information, see the Prescription Drug Abuse Research Report.
Street Names
Commercial Names
(Common)
Common Forms
Common Ways Taken
DEA
Schedule
Bennies, Black
Beauties, Crosses,
Hearts, LA
Turnaround, Speed,
Truck Drivers, Uppers
Amphetamine
(Adderall®,
Benzedrine®)
Tablet, capsule
Swallowed, snorted,
smoked, injected
II
JIF, MPH, R-ball,
Skippy, The Smart
Drug, Vitamin R
Methylphenidate
(Concerta®, Ritalin®)
Liquid, tablet, chewable
tablet, capsule
Swallowed, snorted,
smoked, injected,
chewed
II
Possible Health Effects
Short-term
Increased alertness, attention, energy; increased blood pressure and heart rate; narrowed
blood vessels; increased blood sugar; opened-up breathing passages.
High doses: dangerously high body temperature and irregular heartbeat; heart failure;
seizures.
Long-term
Heart problems, psychosis, anger, paranoia.
Other Health-related
Issues
Risk of HIV, hepatitis, and other infectious diseases from shared needles.
In Combination with
Alcohol
Masks the depressant action of alcohol, increasing risk of alcohol overdose; may increase
blood pressure and jitters.
Withdrawal
Symptoms
Depression, tiredness, sleep problems.
Treatment Options
Medications
There are no FDA-approved medications to treat stimulant addiction.
Behavioral Therapies
Behavioral therapies that have helped treat addiction to cocaine or methamphetamine may
be useful in treating prescription stimulant addiction.
Psilocybin
A hallucinogen in certain types of mushrooms that grow in parts of South America, Mexico, and the United States. For
more information, see the Hallucinogens and Dissociative Drugs Research Report.
Street Names
Little Smoke, Magic
Mushrooms, Purple
Passion, Shrooms
Commercial Names
No commercial uses
Common Forms
Common Ways Taken
DEA
Schedule
Fresh or dried
mushrooms with long,
slender stems topped by
caps with dark gills
Swallowed (eaten,
brewed as tea, or added
to other foods)
I
Possible Health Effects
Hallucinations, altered perception of time, inability to tell fantasy from reality, panic, muscle
relaxation or weakness, problems with movement, enlarged pupils, nausea, vomiting, drowsiness.
Risk of flashbacks and memory problems.
Risk of poisoning if a poisonous mushroom is accidentally used.
May decrease the perceived effects of alcohol.
Unknown.
Treatment Options
It is not known whether psilocybin is addictive. There are no FDA-approved medications to
treat addiction to psilocybin or other hallucinogens.
More research is needed to find out if psilocybin is addictive and whether behavioral
therapies can be used to treat addiction to this or other hallucinogens.
Rohypnol® (Flunitrazepam)
A benzodiazepine chemically similar to prescription sedatives such as Valium® and Xanax®. Teens and young adults
tend to abuse this drug at bars, nightclubs, concerts, and parties. It has been used to commit sexual assaults due to its
ability to sedate and incapacitate unsuspecting victims.
Street Names
Circles, Date Rape Drug,
Forget Pill, Forget-Me Pill,
La Rocha, Lunch Money,
Mexican Valium, Mind
Eraser, Pingus, R2,
Reynolds, Rib, Roach,
Roach 2, Roaches,
Roachies, Roapies, Rochas
Dos, Roofies, Rope,
Rophies, Row-Shay, Ruffies,
Trip-and-Fall, Wolfies
Commercial Names
Flunitrazepam,
Rohypnol®
Common Forms
Tablet
Common Ways Taken
DEA
Schedule
Swallowed (as a pill or
as dissolved in a drink),
snorted
IV
Rohypnol®
is not
approved
for medical
use in the
United
States; it is
available as
a
prescription
sleep aid in
other
countries
Possible Health Effects
Short-term
Drowsiness, sedation, sleep; amnesia, blackout; decreased anxiety; muscle relaxation,
impaired reaction time and motor coordination; impaired mental functioning and judgment;
confusion; aggression; excitability; slurred speech; headache; slowed breathing and heart
rate.
Long-term
Unknown.
Other Health-related
Issues
Unknown.
In Combination with
Alcohol
Severe sedation, unconsciousness, and slowed heart rate and breathing, which can lead to
death.
Withdrawal
Symptoms
Headache; muscle pain; extreme anxiety, tension, restlessness, confusion, irritability;
numbness and tingling of hands or feet; hallucinations, delirium, convulsions, seizures, or
shock.
Treatment Options
Medications
There are no FDA-approved medications to treat addiction to Rohypnol® or other
prescription sedatives.
Behavioral Therapies
More research is needed to find out if behavioral therapies can be used to treat addiction to
Rohypnol® or other prescription sedatives.
Salvia
A dissociative drug (Salvia divinorum) that is an herb in the mint family native to southern Mexico. Dissociative drugs
are hallucinogens that cause the user to feel detached from reality. For more information, see the Hallucinogens and
Dissociative Drugs Research Report.
Street Names
Magic mint, Maria
Pastora, Sally-D,
Shepherdess’s Herb,
Diviner’s Sage
Commercial Names
Sold legally in most
states as Salvia
divinorum
Common Forms
Fresh or dried leaves
Common Ways Taken
Smoked, chewed, or
brewed as tea
DEA
Schedule
Not
Scheduled
(but
labeled
drug of
concern
by DEA
and illegal
in some
states)
Possible Health Effects
Short-term
Short-lived but intense hallucinations; altered visual perception, mood, body sensations;
mood swings, feelings of detachment from one’s body; sweating.
Long-term
Unknown.
Other Health-related
Issues
Unknown.
In Combination with
Alcohol
Unknown.
Withdrawal
Symptoms
Unknown.
Treatment Options
Medications
It is not known whether salvia is addictive. There are no FDA-approved medications to treat
addiction to salvia or other dissociative drugs.
Behavioral Therapies
More research is needed to find out if salvia is addictive, but behavioral therapies can be
used to treat addiction to dissociative drugs.
Steroids (Anabolic)
Man-made substances used to treat conditions caused by low levels of steroid hormones in the body and abused to
enhance athletic and sexual performance and physical appearance. For more information, see the Anabolic Steroid
Abuse Research Report.
Street Names
Juice, Gym Candy,
Pumpers, Roids
Commercial Names
(Common)
Common Forms
Nandrolone
(Oxandrin®),
oxandrolone
(Anadrol®),
oxymetholone
(Winstrol®), stanozolol
(Durabolin®),
testosterone cypionate
(Depo-testosterone®)
Tablet, capsule, liquid
drops, gel, cream, patch,
injectable solution
Common Ways Taken
DEA
Schedule
Injected, swallowed,
applied to skin
III
Possible Health Effects
Short-term
Headache, acne, fluid retention (especially in the hands and feet), oily skin, yellowing of the
skin and whites of the eyes, infection at the injection site.
Long-term
Kidney damage or failure; liver damage; high blood pressure, enlarged heart, or changes in
cholesterol leading to increased risk of stroke or heart attack, even in young people;
aggression; extreme mood swings; anger ("roid rage"); paranoid jealousy; extreme
irritability; delusions; impaired judgment.
Other Health-related
Issues
Males: shrunken testicles, lowered sperm count, infertility, baldness, development of
breasts, increased risk for prostate cancer.
Females: facial hair, male-pattern baldness, menstrual cycle changes, enlargement of the
clitoris, deepened voice.
Adolescents: stunted growth.
Risk of HIV, hepatitis, and other infectious diseases from shared needles.
In Combination with
Alcohol
Increased risk of violent behavior.
Withdrawal
Symptoms
Mood swings; tiredness; restlessness; loss of appetite; insomnia; lowered sex drive;
depression, sometimes leading to suicide attempts.
Treatment Options
Medications
Hormone therapy
Behavioral Therapies
More research is needed to find out if behavioral therapies can be used to treat steroid
addiction.
Synthetic Cannabinoids
A wide variety of herbal mixtures containing man-made cannabinoid chemicals related to THC in marijuana but often
much stronger and more dangerous. Sometimes misleadingly called "synthetic marijuana" and marketed as a
"natural," "safe," legal alternative to marijuana. For more information, see the Synthetic Cannabinoids DrugFacts.
Street Names
Commercial Names
K2, Spice, Black
Mamba, Bliss, Bombay
Blue, Fake Weed, Fire,
Genie, Moon Rocks,
Skunk, Smacked,
Yucatan, Zohai
No commercial uses
Common Forms
Dried, shredded plant
material that looks like
potpourri and is
sometimes sold as
"incense"
Common Ways Taken
DEA
Schedule
Smoked, swallowed
(brewed as tea)
I
Possible Health Effects
Short-term
Increased heart rate; vomiting; agitation; confusion; hallucinations, anxiety, paranoia;
increased blood pressure and reduced blood supply to the heart; heart attack.
Long-term
Unknown.
Other Health-related
Issues
Use of synthetic cannabinoids has led to an increase in emergency room visits in certain
areas.
In Combination with
Alcohol
Unknown.
Withdrawal
Symptoms
Headaches, anxiety, depression, irritability.
Treatment Options
Medications
There are no FDA-approved medications to treat synthetic cannabinoid addiction.
Behavioral Therapies
More research is needed to find out if behavioral therapies can be used to treat synthetic
cannabinoid addiction.
Synthetic Cathinones ("Bath Salts")
An emerging family of drugs containing one or more synthetic chemicals related to cathinone, a stimulant found
naturally in the khat plant. Examples of such chemicals include mephedrone, methylone, and 3,4methylenedioxypyrovalerone (MDPV). For more information, see the Synthetic Cathinones ("Bath Salts") DrugFacts.
Street Names
Commercial Names
Common Forms
Common Ways
Taken
DEA
Schedule
Bloom, Cloud Nine,
Cosmic Blast, Flakka,
Ivory Wave, Lunar
Wave, Scarface, Vanilla
Sky, White Lightning
No commercial uses
for ingested "bath
salts"
White or brown crystalline
powder sold in small plastic
or foil packages labeled "not
for human consumption" and
sometimes sold as jewelry
cleaner; tablet, capsule,
liquid
Swallowed,
snorted, injected
I
Some
formulations
have been
banned by
the DEA
Possible Health Effects
Short-term
Increased heart rate and blood pressure; euphoria; increased sociability and sex drive;
paranoia, agitation, and hallucinations; psychotic and violent behavior; nosebleeds;
sweating; nausea, vomiting; insomnia; irritability; dizziness; depression; suicidal thoughts;
panic attacks; reduced motor control; cloudy thinking.
Long-term
Breakdown of skeletal muscle tissue; kidney failure; death.
Other Health-related
Issues
Risk of HIV, hepatitis, and other infectious diseases from shared needles.
In Combination with
Alcohol
Unknown.
Withdrawal
Symptoms
Depression, anxiety, problems sleeping, tremors, paranoia.
Treatment Options
Medications
Behavioral Therapies
There are no FDA-approved medications to treat addiction to synthetic cathinones.
•
•
•
•
Cognitive-behavioral therapy (CBT)
Contingency management, or motivational incentives
Motivational Enhancement Therapy (MET)
Behavioral treatments geared to teens
Tobacco
Plant grown for its leaves, which are dried and fermented before use. For more information, see the
Tobacco/Nicotine Research Report.
Street Names
None
Commercial Names
Multiple brand names
Common Forms
cigarettes, cigars, bidis,
hookahs, smokeless
tobacco (snuff, spit
tobacco, chew)
Common Ways Taken
Smoked, snorted,
chewed, vaporized
DEA
Schedule
Not
Scheduled
Possible Health Effects
Short-term
Increased blood pressure, breathing, and heart rate.
Long-term
Greatly increased risk of cancer, especially lung cancer when smoked and oral cancers when
chewed; chronic bronchitis; emphysema; heart disease; leukemia; cataracts; pneumonia.
Other Health-related
Issues
Pregnancy: miscarriage, low birth weight, premature delivery, stillbirth, learning and
behavior problems.
In Combination with
Alcohol
Unknown.
Withdrawal
Symptoms
Irritability, attention and sleep problems, increased appetite.
Treatment Options
Medications
Behavioral Therapies
•
Bupropion (Zyban®)
•
Varenicline (Chantix®)
•
Nicotine replacement (gum, patch, lozenge)
•
Cognitive-behavioral therapy (CBT)
Self-help materials
Mail, phone, and Internet quit resources
•
•