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Yuly F. Fuentes-Medel
"Connecting scientist & Economy...Making Science Happen"
Postdoctoral Associate
MIT Sloan School of Management
Technology, Innovation and Entrepreneurship group
100 Main Street, E62-361
Cambridge, MA 02142
[email protected]
Education
2012
Ph.D. Biomedical Sciences, Neuroscience Program. University of Massachusetts Medical
School
Thesis: Role of Glia at the Neuromuscular Junction in Drosophila estás publciada? Poner
el link.
2005
M.S. Summa Cum Laude in Biochemistry, University of Concepcion, Chile
Carried out research at the Brudnick Neuropsychiatric Research Institute, University of
Massachusetts Medical School, as an exchange student during this time period
Thesis: Transcriptional repression by a conserved intronic sequence in the nicotinic
receptor alpha 3 subunit gene está publicada? Poner el link
1997- 2002
B.S. in Biochemistry, University of Concepcion, Chile
Career/Employment
March 2012 – present
MIT Sloan School of Management, Postdoctoral Associate Technological Innovation,
Entrepreneurship, & Strategy, Fellow of Bill & Melinda Gates Foundation. Falta el tema
MOG
2012-present Conference Encuentros Boston 2013, Chief Operation Officer
2011- present Propel Careers, Marketing and Outreach Intern
2010- present Founder and Co-scientific organizer Small Brains, Big Ideas workshop
2003- 2005
Brudnick Neuropsychiatric Research Institute, Research Associate
2003
UdeC, Coordinator Outreach Biochemistry program to High school students
2002
Torrejon Clinical laboratories, Clinical Biochemist
Awards/Honors
 Women entrepreneurs in science and technology (WEST) Giving back award, 2011
 Student speaker (selected by the Organizing Committee) at the 14th Annual Research Retreat at
Woods Hole, MA, University Massachusetts Medical School , 2009
 Dan Muller Award for Scientific Achievement, for excellence in poster preparation and
presentation at the 11th Annual Research Retreat at Woods Hole, MA, University Massachusetts
Medical School, 2006
 Bachelor’s Degree in Biochemistry. “Best clinical research internship”. 2003 Regional Public
Hospital Bio-Bio region, Chile Title: Standardization of new detection protocol for Malassezia
furfur in premature infants at the Neonatal ICU
Publications
Fuentes-Medel Y, Ashley J, Barria R, Maloney R, Freeman M, Budnik V. Integration of a Retrograde Signal
during Synapse Formation by Glia-Secreted TGF-β Ligand. Curr Biol. 2012 Sep 5
Kerr KS, Fuentes-Medel Y, Freeman MR, Budnik V. Glial Wg Control of Synapse Assembly at the
Drosophila Neuromuscular Junction (In preparation)
Bruschweiler-Li L, Fuentes-Medel YF, Scofield MD, Trang EB, Binke SA, Gardner PD. Temporally- and
spatially-regulated transcriptional activity of the nicotinic acetylcholine receptor beta 4 subunit gene
promoter. Neuroscience, 2010 Mar 31;166(3):864-77
Fuentes-Medel Y, Logan MA, Ashley J, Ataman B, Budnik V, Freeman MR. Glia and muscle sculpt
neuromuscular arbors by engulfing destabilized synaptic boutons and shed presynaptic debris. PLoS Biol.
2009 Aug;7(8).
Commented on: Chung WS, Barres BA. Selective remodeling: refining neural connectivity at the
neuromuscular junction. PLoS Biol. 2009 Aug;7(8).
Research Highlighted: Synaptic remodeling: Sculpting the NMJ Katherine Whalley Nature Reviews
Neuroscience 10, 698 (October 2009)
Fuentes Medel, Y.F. and Gardner, P.D. Transcriptional repression by a conserved intronic sequence in the
J Biol Chem. 2007 Jun 29;282(26):19062-70.
Blanchette, A.R.*, Fuentes Medel, Y.F.* and Gardner, P.D. Cell-type-specific and developmental regulation
of heterogeneous nuclear ribonucleoprotein K mRNA in the rat nervous system. Gene Expr Patterns. 2006
Aug;6(6):596-606. (* - co-first authors)
Magdalena E. Cuevas, Mónica A. Carrasco, Yuly Fuentes, Patricio Castro, Francisco Nualart, Jorge Roa, and
Luis G. Aguayo. The presence of glia stimulates the appearance of glycinergic synaptic transmission in
spinal cord neurons. Molecular and Cellular Neuroscience 28(2005)770-778.
Minireview
Fuentes-Medel Y, Budnik V. Ménage à Trio during BMP-Mediated Retrograde Signaling at the NMJ.
Neuron. 2010 May 27;66(4):473-5.
Meetings (Talks and Posters)
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Glial Control of Synapse Assembly at the Neuromuscular Junction. Kerr KS, Fuentes-Medel Y,
Freeman MR, Budnik V. Department of Neurobiology, University of Massachusetts Medical
School, Worcester, MA. 52nd Annual Drosophila Research Conference, 2011, Cold Spring Harbor,
NY (Talk)
Synaptic Nervy is regulated by the Frizzled Nuclear Import pathway. Romina Barria, Yuly FuentesMedel , Sean Speese, and Vivian Budnik. Department of Neurobiology, University of
Massachusetts Medical School, Worcester, MA. Chilean Society for Cell Biology XXIV annual
meeting, 2010 ( Poster)
Glia and muscle sculpt neuromuscular arbors by engulfing destabilized synaptic boutons and
shed presynaptic debris. Fuentes-Medel Y, Logan MA, Ashley J, Ataman B, Budnik V, Freeman
MR. (2009) Department of Neurobiology, University of Massachusetts Medical School,
Worcester, MA. Neurobiology of Drosophila. Cold Spring Harbor, NY (Poster)
Continuous engulfment of presynaptic components by glial and muscle cells sculpts synaptic
connectivity at the neuromuscular junction. Yuly Fuentes, Mary Logan, Vivian Budnik and Marc
Freeman (2007) Department of Neurobiology, University of Massachusetts Medical School,
Worcester, MA. Glia in Health and Disease. Cold Spring Harbor, NY (Talk)
Regulation of synaptic development by Scribble and its synaptic partner dPix. Fuentes-Medel Y,
Shirin Marfatia and Vivian Budnik. 11th Annual Research Retreat at Woods Hole, MA University
Massachusetts Medical School 2006 (Poster)
Transcriptional repression by a conserved intronic sequence in the nicotinic receptor α3 subunit
gene Y.Fuentes1,2; A.Zampini2; P.D.Gardner2 .1. Facultad de Farmacia, Universidad de
Concepcion, Concepcion, Chile; 2. Brudnick Neuropsychiatric Research Institute, Univ. of
Massachusetts Med. Sch., Worcester, MA, USA. Society for Neuroscience Annual Meeting, San
Diego, CA, USA, 2004. (Poster)
The presence of glia stimulates the appearance of glycinergic synaptic transmission in cultured
spinal cord neurons. M. Cuevas, Y. Fuentes, P.Castro, M.A.Carrasco; J.Parodi, L.G.Aguayo
Department of Physiology, University of Concepcion, Concepcion, Chile. Society for Neuroscience
Annual Meeting, San Diego, CA, USA, 2004. (Poster)
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Homeostatic synaptic plasticity after blockade of glycinergic activity in spinal cord neurons. M.A.
Carrasco1, J.C. Tapia1, B. van Zundert1, Y. Fuentes1, F.J. Alvarez2, H.H. Yeh3, L.G. Aguayo1.1
Department of Physiology, University of Concepcion, Concepcion, Chile. 2 Department of
Anatomy, Wright State University, Dayton, OH, USA. 3 Center for Again and Developmental
Biology, University of Rochester, Rochester, NY, USA. Neuroscience meeting, Orlando, USA, 2002.
(Poster)
Culture of mice (C57BL/J6) spinal neurons enriched in motoneurons. Fuentes Y., van Zundert B.,
Aguayo L.G. Department of Physiology. Departmental meeting, University of Concepcion, 2001.
(Talk)
Presence of homeostatic synaptic depends on glycinergic activity in spinal neurons. Carrasco M.,
Tapia J.C., van Zundert B., Díaz E., Fuentes Y., Aguayo L.G. Department of Physiology, Laboratory
of Neurophysiology, Faculty of Biological Sciences. Annual meeting of the Society of Biology of
Chile, Chile 2001. (Talk)
Effect of glucose on lymphocyte proteins obtained from type 2 diabetes mellitus patients.
Rodriguez C., Fuentes Y., Perez M.*, Silva V., Lamperti L., and González M. Department of Clinical
Biochemistry and Immunology, University of Concepcion, and *Faculty of Medicine, Catholic
University of the Santisima Concepcion. Annual meeting of the society of Biology of Chile, Chile
2000. (Talk)
Teaching experience
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Teaching assistant, Cold Spring Harbor Laboratory course, Neurobiology of Drosophila, 2007
Rotation student training ( Kimberly Kerr, PhD Candidate UMass Medical School) 2007
Worcester Polytechnic Institute undergraduate students thesis project, 2004. University of
Massachusetts Medical School.
Under-graduate courses of Biochemistry, 2002. University of Concepcion, Chile
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CONFERENCES
Acá debes poner en que conferencias haz sido invitada a hablar!
Course attendance/Workshops
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11th Annual Intensive Course in Quantitative Fluorescence Microscopy, Mount Desert Island
Biological Laboratory Salisbury Cove, ME. 2009
Co-organizer, International workshop “Small Brains Big Ideas” Biomedical Insights from
Invertebrate Neuroscience Research, Santiago, Chile, 2010-2012.
Internships/Memberships
Intern, Propel Careers, Boston MA
 Responsible for student outreach for Propel Careers
 Participated in social media and marketing efforts for Propel Careers
2011
Intern, Mycology division, Microbiology Laboratory, Regional Hospital, Bio Bio Region, Chile 2002-2003
 Standardization of new detection protocol for Malassezia furfur in premature infants at the
Neonatal ICU
Member, Women entrepreneurs in Science and Technology (WEST)
 Volunteer work for organization of monthly events
2010 to present