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Yuly F. Fuentes-Medel "Connecting scientist & Economy...Making Science Happen" Postdoctoral Associate MIT Sloan School of Management Technology, Innovation and Entrepreneurship group 100 Main Street, E62-361 Cambridge, MA 02142 [email protected] Education 2012 Ph.D. Biomedical Sciences, Neuroscience Program. University of Massachusetts Medical School Thesis: Role of Glia at the Neuromuscular Junction in Drosophila estás publciada? Poner el link. 2005 M.S. Summa Cum Laude in Biochemistry, University of Concepcion, Chile Carried out research at the Brudnick Neuropsychiatric Research Institute, University of Massachusetts Medical School, as an exchange student during this time period Thesis: Transcriptional repression by a conserved intronic sequence in the nicotinic receptor alpha 3 subunit gene está publicada? Poner el link 1997- 2002 B.S. in Biochemistry, University of Concepcion, Chile Career/Employment March 2012 – present MIT Sloan School of Management, Postdoctoral Associate Technological Innovation, Entrepreneurship, & Strategy, Fellow of Bill & Melinda Gates Foundation. Falta el tema MOG 2012-present Conference Encuentros Boston 2013, Chief Operation Officer 2011- present Propel Careers, Marketing and Outreach Intern 2010- present Founder and Co-scientific organizer Small Brains, Big Ideas workshop 2003- 2005 Brudnick Neuropsychiatric Research Institute, Research Associate 2003 UdeC, Coordinator Outreach Biochemistry program to High school students 2002 Torrejon Clinical laboratories, Clinical Biochemist Awards/Honors Women entrepreneurs in science and technology (WEST) Giving back award, 2011 Student speaker (selected by the Organizing Committee) at the 14th Annual Research Retreat at Woods Hole, MA, University Massachusetts Medical School , 2009 Dan Muller Award for Scientific Achievement, for excellence in poster preparation and presentation at the 11th Annual Research Retreat at Woods Hole, MA, University Massachusetts Medical School, 2006 Bachelor’s Degree in Biochemistry. “Best clinical research internship”. 2003 Regional Public Hospital Bio-Bio region, Chile Title: Standardization of new detection protocol for Malassezia furfur in premature infants at the Neonatal ICU Publications Fuentes-Medel Y, Ashley J, Barria R, Maloney R, Freeman M, Budnik V. Integration of a Retrograde Signal during Synapse Formation by Glia-Secreted TGF-β Ligand. Curr Biol. 2012 Sep 5 Kerr KS, Fuentes-Medel Y, Freeman MR, Budnik V. Glial Wg Control of Synapse Assembly at the Drosophila Neuromuscular Junction (In preparation) Bruschweiler-Li L, Fuentes-Medel YF, Scofield MD, Trang EB, Binke SA, Gardner PD. Temporally- and spatially-regulated transcriptional activity of the nicotinic acetylcholine receptor beta 4 subunit gene promoter. Neuroscience, 2010 Mar 31;166(3):864-77 Fuentes-Medel Y, Logan MA, Ashley J, Ataman B, Budnik V, Freeman MR. Glia and muscle sculpt neuromuscular arbors by engulfing destabilized synaptic boutons and shed presynaptic debris. PLoS Biol. 2009 Aug;7(8). Commented on: Chung WS, Barres BA. Selective remodeling: refining neural connectivity at the neuromuscular junction. PLoS Biol. 2009 Aug;7(8). Research Highlighted: Synaptic remodeling: Sculpting the NMJ Katherine Whalley Nature Reviews Neuroscience 10, 698 (October 2009) Fuentes Medel, Y.F. and Gardner, P.D. Transcriptional repression by a conserved intronic sequence in the J Biol Chem. 2007 Jun 29;282(26):19062-70. Blanchette, A.R.*, Fuentes Medel, Y.F.* and Gardner, P.D. Cell-type-specific and developmental regulation of heterogeneous nuclear ribonucleoprotein K mRNA in the rat nervous system. Gene Expr Patterns. 2006 Aug;6(6):596-606. (* - co-first authors) Magdalena E. Cuevas, Mónica A. Carrasco, Yuly Fuentes, Patricio Castro, Francisco Nualart, Jorge Roa, and Luis G. Aguayo. The presence of glia stimulates the appearance of glycinergic synaptic transmission in spinal cord neurons. Molecular and Cellular Neuroscience 28(2005)770-778. Minireview Fuentes-Medel Y, Budnik V. Ménage à Trio during BMP-Mediated Retrograde Signaling at the NMJ. Neuron. 2010 May 27;66(4):473-5. Meetings (Talks and Posters) Glial Control of Synapse Assembly at the Neuromuscular Junction. Kerr KS, Fuentes-Medel Y, Freeman MR, Budnik V. Department of Neurobiology, University of Massachusetts Medical School, Worcester, MA. 52nd Annual Drosophila Research Conference, 2011, Cold Spring Harbor, NY (Talk) Synaptic Nervy is regulated by the Frizzled Nuclear Import pathway. Romina Barria, Yuly FuentesMedel , Sean Speese, and Vivian Budnik. Department of Neurobiology, University of Massachusetts Medical School, Worcester, MA. Chilean Society for Cell Biology XXIV annual meeting, 2010 ( Poster) Glia and muscle sculpt neuromuscular arbors by engulfing destabilized synaptic boutons and shed presynaptic debris. Fuentes-Medel Y, Logan MA, Ashley J, Ataman B, Budnik V, Freeman MR. (2009) Department of Neurobiology, University of Massachusetts Medical School, Worcester, MA. Neurobiology of Drosophila. Cold Spring Harbor, NY (Poster) Continuous engulfment of presynaptic components by glial and muscle cells sculpts synaptic connectivity at the neuromuscular junction. Yuly Fuentes, Mary Logan, Vivian Budnik and Marc Freeman (2007) Department of Neurobiology, University of Massachusetts Medical School, Worcester, MA. Glia in Health and Disease. Cold Spring Harbor, NY (Talk) Regulation of synaptic development by Scribble and its synaptic partner dPix. Fuentes-Medel Y, Shirin Marfatia and Vivian Budnik. 11th Annual Research Retreat at Woods Hole, MA University Massachusetts Medical School 2006 (Poster) Transcriptional repression by a conserved intronic sequence in the nicotinic receptor α3 subunit gene Y.Fuentes1,2; A.Zampini2; P.D.Gardner2 .1. Facultad de Farmacia, Universidad de Concepcion, Concepcion, Chile; 2. Brudnick Neuropsychiatric Research Institute, Univ. of Massachusetts Med. Sch., Worcester, MA, USA. Society for Neuroscience Annual Meeting, San Diego, CA, USA, 2004. (Poster) The presence of glia stimulates the appearance of glycinergic synaptic transmission in cultured spinal cord neurons. M. Cuevas, Y. Fuentes, P.Castro, M.A.Carrasco; J.Parodi, L.G.Aguayo Department of Physiology, University of Concepcion, Concepcion, Chile. Society for Neuroscience Annual Meeting, San Diego, CA, USA, 2004. (Poster) Homeostatic synaptic plasticity after blockade of glycinergic activity in spinal cord neurons. M.A. Carrasco1, J.C. Tapia1, B. van Zundert1, Y. Fuentes1, F.J. Alvarez2, H.H. Yeh3, L.G. Aguayo1.1 Department of Physiology, University of Concepcion, Concepcion, Chile. 2 Department of Anatomy, Wright State University, Dayton, OH, USA. 3 Center for Again and Developmental Biology, University of Rochester, Rochester, NY, USA. Neuroscience meeting, Orlando, USA, 2002. (Poster) Culture of mice (C57BL/J6) spinal neurons enriched in motoneurons. Fuentes Y., van Zundert B., Aguayo L.G. Department of Physiology. Departmental meeting, University of Concepcion, 2001. (Talk) Presence of homeostatic synaptic depends on glycinergic activity in spinal neurons. Carrasco M., Tapia J.C., van Zundert B., Díaz E., Fuentes Y., Aguayo L.G. Department of Physiology, Laboratory of Neurophysiology, Faculty of Biological Sciences. Annual meeting of the Society of Biology of Chile, Chile 2001. (Talk) Effect of glucose on lymphocyte proteins obtained from type 2 diabetes mellitus patients. Rodriguez C., Fuentes Y., Perez M.*, Silva V., Lamperti L., and González M. Department of Clinical Biochemistry and Immunology, University of Concepcion, and *Faculty of Medicine, Catholic University of the Santisima Concepcion. Annual meeting of the society of Biology of Chile, Chile 2000. (Talk) Teaching experience Teaching assistant, Cold Spring Harbor Laboratory course, Neurobiology of Drosophila, 2007 Rotation student training ( Kimberly Kerr, PhD Candidate UMass Medical School) 2007 Worcester Polytechnic Institute undergraduate students thesis project, 2004. University of Massachusetts Medical School. Under-graduate courses of Biochemistry, 2002. University of Concepcion, Chile CONFERENCES Acá debes poner en que conferencias haz sido invitada a hablar! Course attendance/Workshops 11th Annual Intensive Course in Quantitative Fluorescence Microscopy, Mount Desert Island Biological Laboratory Salisbury Cove, ME. 2009 Co-organizer, International workshop “Small Brains Big Ideas” Biomedical Insights from Invertebrate Neuroscience Research, Santiago, Chile, 2010-2012. Internships/Memberships Intern, Propel Careers, Boston MA Responsible for student outreach for Propel Careers Participated in social media and marketing efforts for Propel Careers 2011 Intern, Mycology division, Microbiology Laboratory, Regional Hospital, Bio Bio Region, Chile 2002-2003 Standardization of new detection protocol for Malassezia furfur in premature infants at the Neonatal ICU Member, Women entrepreneurs in Science and Technology (WEST) Volunteer work for organization of monthly events 2010 to present