Download 45075 Molecular Evolution

1. COURSE DECRIPTION – GENERAL INFORMATION
1.1. Course teacher
Franjevic Damjan
1.2. Name of the course
Molecular Evolution
1.3. Associate teachers
1.4. Study programme (undergraduate,
graduate, integrated)
Graduate
Obligatory
1.5. Status of the course
1.6. Year and semester of study
1.7. Credit value (ECTS)
1.8. Type of instruction (number of hours
L+S+E+e-learning)
1.9. Expected enrolment in the course
4th/winter
5
2+2+1+0
15
1.10. Level of use of e-learning (1, 2, 3
level), percentage of instruction in the
course on line (20% maximum)
2. COURSE DESCRIPTION
2.1. Course objectives
2.2. Enrolment requirements and
required entry competences for the
course
2.3. Learning outcomes at the level of
the study programme to which the
course contributes
2.4. Expected learning outcomes at the
level of the course (4-10 learning
outcomes)
2.5. Course content broken down in
detail by weekly class schedule
(syllabus)
Introduction to all aspects and methods in molecular evolution. Learning different types of phylogenetics analysis and
their application in molecular evolution. Application of molecular evolution in experimental work
Genetics, Evolution, Biochemistry
Possibility of implementation of molecular evolutionary methods in future scientific work and preparation for
independent experimental work
Recognition of basic mechanisms of molecular evolution. Detection of problems in biology based on molecular
evolution. Application of knowledge from molecular evolution in future scientific work. Implementation of molecular
phylogenetic inference. Mathematical and statistical methods in molecular evolution.
What is molecular evolution? History of molecular evolution. Methodology in molecular evolution with practical primer.
Molecular evolution and morphology. Role of mutations, selection and drift in molecular evolution. Molecular clock
theory. Neutral theory of molecular evolution. Evolution through domain duplication and domain shuffling. Evolution
via horizontal gene transfer and transposition. Concerted evolution of multigene families. Genome organization.
Protein evolution. Tree of life. Ancient DNA. Molecular phylogenetics. Sampling, methodology and analysis in molecular
phylogenetics. Genome projects. Bioinformatic methodology in molecular phylogenetics. Convergent and parallel
evolution. Molecular ecology. Molecular anthropology.
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2.6. Type of instruction
lectures
seminars and workshops
exercises
online in entirety
mixed e-learning
field work
independent study
multimedia and the internet
laboratory
work with the mentor
2.7. Comments:
(other)
2.8. Student responsibilities
Regular attendance of lectures, laboratory work and seminars. Student’s presentation of seminar works.
2.9. Screening of student’s work (specify
the proportion of ECTS credits for
each activity so that the total number
of CTS credits is equal to the credit
value of the course)):
Class attendance
Experimental work
Essay
Tests
Written exam
2.1. Grading and evaluation of student
work over the course of instruction
and at a final exam
Seminar essay, written and oral final exam
2
1
Research
Report
Seminar essay
Oral exam
Project
Practical training
2
(Other--describe)
(Other—describe)
(Other—describe)
Number of
copies at the
library
Title
2.2. Required literature (available at the
library and via other media)
2.12. Optional literature (at the time of
the submission of the study
programme proposal)
2.13. Methods of monitoring quality that
ensure acquisition of exit
competences
Wen-Hsiung Li: Molecular Evolution. Sinauer Assotiates, Inc.
Nei M & Kumar S: Molecular Evolution and Phylogenetics. Oxford University Press
Patthy Laslo: Protein Evolution, Second Edition. Blackwell Publishing
2
1
1
Higgs G. Paul & Attwood K. Teresa: Bioinformatics and Molecular Evolution. Blackwell Publishing
Written Final Exam
2
Availability via
other media
1
1
1