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Case Report: Successful Treatment of Stevens Johnson Syndrome-Toxic Epidermal Necrolysis with Intravenous Immunoglobulin<br> Author : Bony Pramono, Ariyanto Harsono Abstract : Steven Johnson Syndrome is a serious disease of the skin characterized by triad of erythema exudativum multiforme lesions affecting skin, orifices and eyes. Immunological basis of this disease is hypersensitivity type III and IV. The differential diagnosis are Staphylococcal Scalded Skin Syndrome and Toxic Epidermal Necrolysis. The mainstay of treatment is discontinuation of previously given drugs. Supportive treatment consisting fluid therapy, skincare, symptomatic and antibiotic for existing skin infection. Intravenous Immunoglobulins is used in severe skin involvement and severe complications including eyes. The prognosis is generally good, fatal outcome is usually due to delayed therapy and severe complication.