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Dear Chris: It is common believe that chelated minerals has better bioavailability. A chelated mineral is one chemically attached to another substance, such as an amino acid or organic acid carrier, called a chelator. The chelator can be a natural or synthetic substance. Chelated minerals are believed to mimic the natural mineral chelates that form during the digestion process. The absorption of the mineral may be enhanced in some cases by chelation. It helps carry the mineral from the digestive tract into the blood and greatly increases the absorption of the mineral. Chromium picolinate is a good example of a mineral whose absorption is improved by chelation. Also, chelated minerals, such as zinc gluconate, may cause less stomach upset and constipation that other mineral forms, such as zinc sulfate, when taken in large amounts. Reference of Interests: Nutritional selenium supplements: product types, quality, and safety. J Am Coll Nutr. 2001 Feb;20(1):1-4 Calcium supplementation. J Am Acad Nurse Pract. 1997 Apr;9(4):187-92. A "colloid" is a substance dispersed in particle size large enough to prevent or delay passage through a semipermeable membrane, but small enough to remain in suspension in a liquid or gas. Particles may be electrically charged and have stabilising agents added to prevent precipitation. Colloidal minerals are basically clays dispersed in water. Such products differ greatly. Some contain aluminium or toxic minerals, others are high in sodium. Some do not contain detectable amounts of minerals listed on their labels. Finally, there is no evidence that colloidal minerals are more bioavailable than those found in other forms. There is however ongoing safety concern relating to supplemental use of colloidal mineral Regards; Sheila Zhou Associate Scientist USANA ANZ Technical Services USANA Health Science USANA ANZ Celebrating 11 Years – Working Together in Partnership