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LHWHS AP BIOLOGY Summer Packet 1. Release of insulin by_____cells in the_____will_____blood sugar levels. a. alpha, liver, increase b. alpha, liver, decrease c. beta, pancreas, increase d. beta, pancreas, decrease 2. Insulin functions as a cell signal molecule by triggering...... a. the release of glycogen from the liver b. the facilitated diffusion of glucose into cells c. microtubule extension from the centrioles d. pollen tube growth 3. Target tissue for insulin includes.... a. brain cells b. virtually all cells except brain cells 4. Glucagon and insulin regulate blood glucose levels by negative feedback. Glucagon triggers the hydrolysis of glycogen and subsequent release of glucose into the bloodstream. Target tissue for glucagon includes..... a. liver cells b. virtually all cells except liver cells 5. When one insulin molecule touches a receptor embedded in the cell membrane, it triggers a cascade of enzymatic activity including the opening of many glucose channels. This is characteristic of a........ a. G protein linked receptor b. tyrosine kinase receptor 6. Glucagon is a hormone which relies on secondary messengers like cAMP (cyclic adenosine mono phosphate) to activate the enzymes which hydrolyze glycogen. When glucagon attaches to the receptor, cAMP is activated by a protein linked to the receptor. This is characteristic of a........ a. G protein linked receptor b. tyrosine kinase receptor 7. Glucagon formation can also be triggered by epinephrine (adrenaline). Epinephrine is released by the.... a. liver b. adrenal glands c. pancreas d. hypothalamus 8. A glycogen molecule consists of a core protein surrounded by branches of glucose. Which of following could help determine the structure of the core protein ? a. column chromatography or size exclusion chromatography (SEC) b. thin layer chromatography (TLC) c. poly-acrylamide gel electrophoresis (PAGE) d. spectroscopy e. all of the above 9. Glycogen has been called "animal starch". Both plant starch and animal glycogen consist of glucose molecules joined by..... a. α glycosidic bonds b. peptide bonds c. phosphodiester bonds 10. Cellulose is another polysaccharide composed of glucose molecules. The structure of the molecule is more linear (less branched) than starch. This is due to the...... a. α glycosidic bonds b. β glycosidic bonds c. peptide bonds d. phosphodiester bonds 11. Which a. b. c. d. enzyme (produced in the salivary glands) enables the hydrolysis of starch ? isomerase polymerase amylase pepsin 12. Often when glycogen (or starch) is broken down, the resulting molecule is glucose-6-phosphate. The same can be true for lipids and proteins which are broken down by enzymes. Using glucose-6-phosphate is _____favorable when considering the thermodynamics of cellular respiration. a. more b. less c. equally 13. Triacerylglycerol (triglyceride or fat) molecules are more dense than the highly branched glycogen molecules. Fat molecules are able to store_____ energy than glycogen molecules. a. more b. less c. an equal 14. Which form of stored energy is more easily mobilized in the body ? a. glycogen b. fat 15. Type I diabetes is diagnosed when cells in the body produce little or no insulin. Often the result is hyperglycemia. Hyperglycemia is when..... a. glucose levels in blood serum are too high b. glucose levels in the blood serum are too low 16. Treatment for type I diabetes includes injections of insulin. If too much insulin is in the bloodstream, then hypoglycemia can occur. Hypoglycemia is when..... a. glucose levels in blood serum are too high b. glucose levels in the blood serum are too low 17. One cause of Type I diabetes is when the body's own white blood cells attack insulin producing cells. This cause is an example of an...... a. immunodeficiency b. hypersensativity leading to anaphylactic response c. auto-immune disease 18. Type II diabetes is characterized by a decreased response to insulin in target tissue. More specifically, ______________become damaged over time. This damage has been correlated with poor diet and a lack of exercise. a. tyrosine kinase receptors b. parietal cells in the stomach c. myelin sheathes d. myosin heads 19. Using genetic engineering, insulin has manufactured drugs in the world. Which manufacturing of insulin ? a. recombinant DNA b. c. restriction enzymes d. become one of the most of the following are used in the plasmids all of the above 20. Having high levels of glucose in your blood plasma can cause hemoglobin molecules to be glycosalated (glucose molecules bind with hemoglobin). This binding interferes with the normal functioning of hemoglobin. This binding interferes with..... a. the ability to transport oxygen b. the ability to control blood pH c. the ability to transport CO2 d. all of the above 21. Hemoglobin is the primary protein found in red blood cells. RBC's are produced in the..... a. heart b. bone marrow c. liver 22. Adult bone marrow contains stem cells which are classified as..... a. pluripotent b. totipotent matching 23. antigen__C___ A. clear fluid obtained when cellular components are removed from blood 24. lymphocyte_B_ 25. antibody__D___ B. white blood cell; could be derived from the thymus (T-cells); could be dervied from the bone marrow (B cells) 26. epitope___E___ C. any agent that triggers an immune response 27. serum___A_ D. immunoglobulin protein that exhibits specific binding E. specific binding site on an antigen Blood plasma pH is held near 7.4. This is because carbonic acid (H2CO3( aq)) in the plasma is in equilibrium with CO2 (g) in the lungs. The first equilibrium is established in blood plasma as follows.... H+ + HCO3- <=====> H2CO3 28. Additional H+ ions would shift the equilibrium.... a. left b. right 29. More _____would be in blood plasma as H+ ions are added. a. H+ b. HCO3c. H2CO3 A second equilibrium is established between capillaries and air space in the lung as follows.... H2CO3(aq) <======> H2O(g) + CO2(g) 30. Removal of CO2(g) from the lung would shift the equilibrium..... a. left b. right 31. Less_____would be in the blood plasma as CO2(g) is removed. a. H2CO3(aq) b. H2O(g) c. CO2(g) 32. Overall, as hydrogen ions are added to blood plasma, the pH is maintained by...... a. adding CO2 b. removing CO2 33. Protein catabolism results in the formation of NH3. NH3 functions as a weak base which lowers the concentration of H+ in the blood plasma. How would the the rate of exhaling CO2 change ? a. increase b. decrease 34. In what form is NH3 generally removed from our body ? a. as urea b. as uric acid c. as ammonia 35. All Proteins are composed of..... a. amino acids b. calcium c. glucose d. sodium 36. Imagine you ate an egg. The protein (albumin) is mainly digested in the ..... a. mouth b. esophagus c. stomach d. small intestine e. large intestine 37. Proteins are broken down with help of..... a. pepsin b. hydrochloric acid c. both a and b 38. A lack of protein in one's diet can cause swelling in the abdomen. This edema is caused by an excess of interstitial fluid. The osmotic pressure of capillary walls determine how much fluid is in the blood vessels and how much fluid is in the interstitial fluid. Which protein is the primary constituent of blood serum ? This protein regulates osmotic pressure in capillaries. a. creatine b. acetylcholine c. albumin d. testosterone 39. Following absorption of nutrients from the digestive tract and into the blood stream, the capillaries and veins carry nutrient rich blood. All blood vessels converge into the hepatic portal vein which leads directly to the____ a. heart b. lungs c. liver d. brain 40. The liver helps regulate glucose concentrations in the blood. From here, blood travels to the ______. a. lung b. brain c. heart d. hypothalamus 41. Oxygen poor blood enters the _______of the heart. a. right side b. left side 42. Oxygen poor blood enters the_______of the heart a. right atrium b. right ventricle 43. Oxygen rich blood enters the______of the heart a. left atrium b. left ventricle 44. The human heart is classified as..... a. myogenic b. neurogenic 45. Buffers are composed of..... a. strong acids and bases b. conjugate weak acid and base pairs 46. Enzymes, hormones, receptor proteins, and other molecules involved with cell signal pathways function best at an optimum.... a. pH b. temperature c. concentration of other surrounding solutes d. all of the above 47. Denaturing changes a protein's..... a. primary structure b. secondary, tertiary, and quaternary structure 48. Competitive inhibitors bind to an enzyme's active site. a. true b. false 49. Non-competitive inhibitors affect enzyme function by changing the active site conformation. These molecules bind to a location other than the enzyme's active site. They are called...... a. catalases b. steroids c. allosteric regulators d. bile salts 50. Which results in the formation of lactic acid (a source of hydrogen ions for blood plasma) ? a. aerobic respiration b. anaerobic respiration 51. Lactic acid formation results from.... a. oxidative phosphorylation b. fermentation 52. Yeast cells undergoing fermentation produce..... a. glucose b. alcohol c. ATP d. both b and c People with diabetes may develop peripheral artery disease in their legs. This leads to a decrease in blood pressure and an increased susceptibility to infection. Often, these infections never heal. Amputation of the limb becomes the only option. (No...we are not talking about the Civil War. This happens in 2011.) 53. Cell signals (hormones) which affect blood vessel dilation (and blood pressure) include.......... a. carotenoids b. actin c. rubisco d. prostaglandins matching 54. smooth muscle_B__ 55. skeletal muscle__A 56. cardiac muscle__C_ A. striated muscle tissue B. contains uniformly distributed myosin filaments; lacks straitions ; surrounds endothelium of blood vessels C. myogenic in humans 57. Normal blood pressure is around 120/70. These units used to measure blood pressure are.... a. PSI b. atm c. kPa d. mmHg 58. Normal blood pressure is around 120/70. 120 is the _______. 70 is the____ a. diastolic , systolic b. systolic, diastolic 59. A _______was used to measure blood pressure during lab. a. sphygmomanometer and stethoscope b. hammer and nail c. spectrophotometer and PCR d. quarter and a machine at Walgreens 60. One theory attempting to explain why infections do not heal is that cells affected by peripheral artery disease do not make as many mitochondria. Cells with fewer mitochondria use less.... a. glucose b. oxygen c. all of the above 61. Cells a. c. c. with fewer mitochondria make less..... ATP NADH all of the above 62. Which of the following cellular activities requires the phosphorylation of enzymes using ATP. In other words, which require energy ? a. DNA replication / transcription / translation b. spindle fiber formation during mitosis c. sliding of actin and myosin heads d. opening/closing of ion channels in nervous tissue e. hormone signal transduction pathways ab. all of the above 63. Which vitamin is used by the body as a precursor for NADH ? a. Vitamin C b. Niacin c. Vitamin K 64. Alcohol consumption can interfere with the absorption of niacin. Absorption of vitamins into the bloodstream occurs in the...... a. microvilli of the small intestine b. parietal cells of the stomach c. pancreas' islet of Langerhans d. nephrons of the kidney 65. Alcohols are a class of molecules characterized by the presence of..... a. -NH2 b. -COOH c. -OH d. =O 66. Proteins are made during... a. transcription b. translation matching 67. ribose____B___ 68. poly A tail___A_ A. adenosine monophosphate (AMP) attached to the 3' end of mRNA; the mRNA is stable and ready for nuclear export and translation 69. intron__C____ B. pentose sugar 70. wobble_D_____ C. noncoding segment of eukaryotic DNA 71. telomere_E____ D. 5' end of tRNA anti-codon; capable of hydrogen bonding with more than one nitrogen base E. repetitive, protective segment at the end of chromosomal DNA matching 72. primer__A_ 73. ligase___D_ 74 promoter region_C_ 75. repressor___E_ 76. polymerase__B_ A. nucleotide that binds to polymerase; indicates where transcription starts B. general name for enzyme that catalyzes the elongation of a nucleotide (RNA or DNA); contains phosphate groups which provide energy for elongation C. nucleotide with a free 3' end that is elongated during DNA replication D. general name for the linking enzyme that covalently bonds the 3' end to the 5' end of the growing nucleotide E. protein that suppresses the transcription of a gene; prevents the binding of polymerase matching 77. frameshift___E_ A. virus that infects bacteria 78. non-disjunction_B__ B. when sister chromatids do not separate properly 79. chiasma___C_ C. where crossing over occurs 80. aneuploidy__D___ D. abnormal number of chromosome bodies; often 81. bacteriophage_A_ the result of non-disjunction E. result of insertion or deletion point mutations matching 82. 83. 84. 85. 86. have have have have have membrane bound organelles__B_ a nuclear envelope__B__ lots of introns__B__ histones in chormosomes___B__ circular chromosomes__A__ 87. heterochromatin A A. prokaryotes B. eukaryotes A. dense, compact, non-transcribed portion of eukaryotic chromosome 88. methylated___B_ 89. oncogene___D__ 90. cyclin_____E_ 91. telomerase__C___ B. portions of eukaryotic DNA which cannot be transcribed have been_____ C. enzyme that catalyzes the elongation of repetitive DNA at the end of a chromosome; often this enzyme is highly active in cancerous cells D. gene that can trigger cancerous growth E. hormone (protein) that regulates the cell cycle 92. HDL_D 93. LDL__E_ A. The Miller-Urey experiment which tested the OparinHaldane hypothesis lacked this gas. The earth's early atmosphere was a strongly reducing system because this gas was not present. 94. NO__B 95. O2 __A B. gas which functions as a neurotransmitter C. result of treating DNA with restriction enzymes 96. RFLP_C D. "good" cholesterol; dense; used to make steroid hormones E. "bad" cholesterol; less dense; leads to plaque formation in arteries 97. Rf = 2.1___A A. more soluble 98. Rf = 1.4___B B. less soluble 99. rubisco___C_ 100. mycorrihizae__E__ 101. melatonin____D_ 102. calcitonin____B_ 103. estrogen___A_ A. steroid hormone; influences development of the reproductive system and secondary sexual characteristics B. secreted by thyroid; promotes calcium deposition in bones; lowers blood levels of calcium C. transports CO2 for use in Calvin cycle; the most abundant protein on earth D. secreted by pineal gland; influences circadian rhythms and sleep cycles E. fungi that increases absorption of nutrients for plant roots 104. after gastrulation, the blastopore becomes the mouth_A 105. after gastrulation, the blastopore becomes the anus_B_ (hint....Which is more primitive ? 106. gradualism__A 107. punctuated equilibrium___B A. protostome B. deuterstome Which structure was first to evolve ?) A. more in line with Darwin's theory of evolution that change is a slow, continuous process B. developed by Stephen J. Gould; evolutionary change occurs in sudden, short bursts followed by long periods of stasis 108. maintain the blood-brain barrier__B A. Gap junctions (communicating junction) 109. between axons and dendrites___A 110. maintain intergrity of epidermal skin cell connections____C B. Tight junctions C. Desmosomes (anchoring junction) 111. sodium ion transport against the charge gradient__A A. active transport 112. when glucose enters a cell___B__ B. facilitated diffusion 113. osmosis__C__ C. passive transport 114. apoptysis__D___ 115. karyotype__A___ A. image of condensed, homologous, chromosomes; picture is taken during metaphase B. plants, some bacteria, some protists 116. autotroph__B___ C. fat with single bonded carbon atoms 117. saturated_C____ 118. oogenesis__E___ D. cell death caused by its own activation of enzymes which degrade the biomolecules E. results in 1 egg and 3 polar bodies 119. conserves the number of chromosomes in daughter cells_A_ A. mitosis 120. results in the formation of haploid cells__B__ B. meiosis 121. glycolysis_A____ A. glucose becomes pyruvate 122. TCA___B__ B. pyruvate becomes CO2 123. oxidative phosphorylation__C__ C. ATP is generated via chemiosmosis of hydrogen ions 124. light reaction___B____ A. carbon atoms from CO2 are reduced using enzymes; glucose is formed 125. Calvin cycle__A_____ B. water molecules are split using electrons absorbed by various pigments 126. have genes which produce amylase allowing starch to become a source of energy; key development in their evolutionary success___A___ A. humans B. chimpanzees 127. primarily rely on fruit and protein for energy; have very low levels (if any) of amylase_B____ 128. When only a few months old, individuals choose to be with others that make similar choices as themselves. This behavior is unique to this species.__A__ Circle the structure which is larger in each pair A...............OR.............B 129. Nucleus of cell .........OR.........Glucose molecule 130. Eukaryote cell..........OR...........carbon atom 131. Protein molecule..........OR.........hydrogen ion 132. hydrogen ion...........OR ..........fatty acid molecule 133. human cheek cell..........OR...........prokaryote cell 134. ribosome..........OR.........plant cell 135. eukaryote...........OR ..........prokaryote 136. 1 cm .......OR........1 mm 137. 1 µm.......OR ........1 nm 138. 10µm.......OR..........1 mm 139. Chromosome.............OR.......individual DNA nucleotide 140. Chromosome.........OR........gene 141. glucose.......OR........ribose