Download Combination of Q-Switched Nd:YAG and Fractional Erbium:YAG

Dear editor
Hereby we submit our work entitled “Combination of Q-Switched Nd:YAG and Fractional Erbium:YAG
Lasers in Treatment of Melasma: a Randomized Controlled Clinical Trial” to Journal of Lasers in Medical
Sciences for review and possible publication.
By submitting this manuscript, we transfer all the publications right and copy right to Journal of Lasers in
Medical Sciences. This work has not been published before or presented in any dermatology or cosmetic
surgery congress. All authors participated in conducting the study and preparing final manuscript and met
eligibility for authorship according to ICMJE. This study has received no grant or financial support and the
authors declare no conflict of interest. The summary of our work is provided below:
Ablative and nonablative lasers have been used alone or in combination to treat pigmentary diseases such
as melasma. For the first time, we employed a combination of Q-switched Nd:YAG and fractional
erbium:YAG lasers along with topical treatment to improve melasma lesions. Before treatment and one
month after four therapy sessions held every other week, we objectively assessed the color changes,
melanin contents, and erythema intensity through biometric devices and achieved significant
improvement with treatment by both laser systems than with Q-switched Nd:YAG laser alone.
I am available for any questions and I hope that we would have a chance to publish our work with you.
Sincerely
Mohammadali Nilforoushzadeh, MD
Associate Professor of Dermatology
Skin and Stem Cell Research Center, Tehran University of Medical Sciences, Tehran, Iran