Download 157-392-2-SP - International Journal of Applied Research in

TO,
The Editor,
International Journal of Applied Research In Natural Products
Sub: Regarding publication of a research article
Dear Sir,
I am pleased to send the research contribution entitled “Application of Neem Gum for
Aqueous Film Coating of Ciprofloxacin Tablets” for publication in your esteemed journal.
The manuscript is an original research article. The manuscript has not been previously
published in any language anywhere and it is not under simultaneous consideration by
another journal. The contributing authors and the authorities (where the research has been
carried out) have agreed for its publication. The contributing authors do not have any
conflicts of interest.
Industrial relevance:
Coating process is often applied to a dosage form that is functionally complete and includes
application of a protective layer on particles, tablets, capsules. Coating serves multiple
functions. An overview of pharmaceutical coating (materials, formulations, and processes)
revealed that there has been a steady transition in the pharmaceutical industry, beginning with
sugar coating, moving to film coating, and finally arriving at aqueous film coating. The
reasons, for shift from organic solvent-based to water-based film coating, are high costs of
organic solvents, possibility of residual solvents in the finished product, adverse effects of
residual solvents on consumer health and government regulations. In case of aqueous film
coating, there is a need to identify critical process parameters and control a range of key
processing factors. Natural polymers have many advantages over the synthetic polymers.
Herbal gums, containing polysaccharides, are widely used in the process of development of
new pharmaceutical formulations. The development of new coating materials and impact of
applied coatings should be evaluated in terms of subsequent release of the drug from the
dosage form. The paper attempts to describe the application of a novel natural polymer, neem
gum, as an aqueous coating material. It also studies the coating process parameters and the in
vitro release of the drug from the neem gum coated tablets.
You are requested to publish the article in your esteemed journal.
Thanking you.
Sincerely,
Dr. A. P. Kulkarni