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Aerosol Therapy and Nebulizers
RET 2274
Respiratory Therapy Theory Lab I
Module 6.1
Aerosol Therapy and Nebulizers

Aerosols

Particulate matter suspended in a gas

Particulate matter can be either a liquid or a solid
Examples:
 Liquid - Albuterol (liquid medication)
 Solid - Cromolyn sodium (powdered medication)
Aerosol Therapy and Nebulizers

Aerosols

Liquids are aerosolized in clinical practice

Bland aerosol therapy (cool or heated)


Agents used

Sterile water

Saline (hypotonic, isotonic, hypertonic)
Use to treat

Airway edema

Humidification of bypassed upper airway
e.g. artificial airway

Sputum induction and mobilization
Aerosol Therapy and Nebulizers

Aerosols

Liquids are aerosolized in clinical practice

Aerosolized medication

Directly to the pulmonary system for treatment of a
pathology

Bronchospasm

Mucosal edema

Infection
Aerosol Therapy and Nebulizers

Aerosol Therapy Equipment

Nebulizer – a device that produces particulate
matter that is delivered into a gas







Large-Volume Nebulizer
Large-Volume Ultrasonic Nebulizer
Small-Volume Nebulizer
Small-Volume Ultrasonic Nebulizer
Bulb-Type Nebulizer
Respigard II Small-volume Nebulizer
Breath-Actuated Nebulizer
Aerosol Therapy and Nebulizers

Aerosol Therapy Equipment

Pneumatic Nebulizer
1.
2.
3.
4.
5.
6.
High pressure nozzle
Maximum shear force
Capillary tube
Baffle
Area of vorticity
Reservoir
Aerosol Therapy and Nebulizers

Aerosol Therapy Equipment

Large-Volume Nebulizer


Pneumatically powered
Variable air entrainment port


Increase flow rate
Alter FiO2
Aerosol Therapy and Nebulizers

Aerosol Therapy Equipment

Large-Volume Nebulizer

Single-patient use
Aerosol Therapy and Nebulizers

Aerosol Therapy Equipment

Large-Volume Nebulizer

Heaters
Aerosol Therapy and Nebulizers

Aerosol Therapy Equipment

Large-Volume Ultrasonic Nebulizer
1.
2.
3.
4.
5.
6.
7.
Radiofrequency generator
Shielded cable
Piezoelectric crystal transducer
Water-filled couplant reservoir
Solution chamber
Chamber inlet
Chamber outlet
Aerosol Therapy and Nebulizers

Aerosol Therapy Equipment

Small-Volume Nebulizer


Pneumatically powered
Medication administration




Bronchodilators
Antiinflammatory agents
Antibiotics
10 ml medication reservoir
Aerosol Therapy and Nebulizers

Aerosol Therapy Equipment

Small-Volume Nebulizer

Single-patient use
Aerosol Therapy and Nebulizers

Aerosol Therapy Equipment

Respirgard II Small-Volume Nebulizer

Administration of Penamidine




Tx for Pneumocystis carinii pneumonia (PCP)
Two one-way valves
Wye
Expiratory filter
Aerosol Therapy and Nebulizers

Aerosol Therapy Equipment

Breath-Actuated Nebulizers



Deliver aerosol only during inspiration
Eliminates waste during exhalation
Increases delivered dose
AeroEclipse
Aerosol Therapy and Nebulizers

AeroEclipse
Aerosol Therapy and Nebulizers

Aerosol Therapy Equipment

Bulb-Type Handheld Nebulizer


Medication administration
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Aerosol Therapy and Nebulizers

Aerosol Therapy Equipment

Small-Volume Ultrasonic Nebulizer


Medication administration
Home use
Aerosol Therapy and Nebulizers

Aerosol Therapy Equipment

Small-Volume Ultrasonic Nebulizer


Medication administration
Mechanical ventilators
Aerosol Therapy and Nebulizers

Aerosol Therapy Equipment

Small-Volume Nebulizer (continuous nebulization)


Intravenous drip system for
Used to manage severe bronchospasm when traditional
dosing strategies are ineffective
Aerosol Therapy and Nebulizers

Aerosol Therapy Equipment

Large-Volume Nebulizer (Continuous
Nebulization)



Medication administration
Used to manage severe bronchospasm
when traditional dosing strategies are
ineffective
240 ml medication reservoir
HOPE
Aerosol Therapy and Nebulizers

Aerosol Therapy Equipment

Small-Particle Aerosol Generator (SPAG)


Special-purpose large-volume nebulizer
Administration of Virazole (ribavirin)


Tx for respiratory syncytial virus (RSV)
Used with masks, hoods, tents, vent circuits
Aerosol Therapy and Nebulizers

Aerosol Therapy Equipment

Airway Appliances

Used to deliver aerosol therapy
A.
B.
C.
D.
A
Aerosol mask
Face tent
T-Tube
Tracheostomy mask
B
C
D
Aerosol Therapy and Nebulizers

Aerosol Therapy Equipment

Metered Dose Inhalers (MDI)

Medication administration


Bronchodilators
Steroids
Aerosol Therapy and Nebulizers

Aerosol Therapy Equipment

MDI Accessory Devices


Reduce oropharyngeal deposition
Eliminate need for hand-breath
coordination
Aerosol Therapy and Nebulizers

Aerosol Therapy Equipment

Dry Powder Inhaler (DPI)


Patient creates an aerosol by drawing air through a dose
of finely milled drug powder
Do not require the hand-breath coordination needed for
MDIs, but do require high inspiratory flows