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Obesity and Microbiome: Concepts and Contradictions Organizers: Shili Lin, Ohio State University Mary Dinauer, Washington University Traditional Risk Factors But how about the couch potato? It’s all Burger’s fault! I got it from Mom and dad. Microbial Community Compositions & Obesity Humans Are we there yet? • Therapeutic targets - altering gut microbiomes of obese individuals • Conflicting reports about relationships between gut microbiota taxonomy compositions and obesity • Large surveys of data from multiple studies have led to inconsistent results • Inter-study variability in fecal microbiome communities exceeds differences between lean and obese individuals Crosstalk Between Experimental & Computational Scientists • Dr. Peter Turnbaugh, Microbiologist (Harvard University) Gut microbial promotion of energy gain on processed diets • Dr. Elhanan Borenstein, Computational Biologist (University of Washington) Studying the human microbiome: From metagenomics systems biology to multi-meta-omic analysis • Dr. Katie Pollard, Statistician (University of California at San Francisco) Variability and potential causes for inconsistencies in human data sets
