Download Cpsp favourite questions with answers

CPSP MOST REPEATED QUESTIONs in FCPS-1
1. Which of the following hormones promotes hypoglycemia?
a. Epinephrine
b. Norepinephrine
c. Insulin
d. Glucagon
e. Glucocorticoids
2.Which of the following aminoacids is a derivative of thyroid hormone?
A) Thyrosine
B) Cystosine
C) Iodine
D) Tyrosine ans
E) Thymine
3.Which one of the following cases is considered a clean-contaminated wound?
a. Open cholecystectomy for cholelithiasis,ans
b. Herniorrhaphy with mesh repair
c. Lumpectomy with axillary node dissection
d. Appendectomy with walled-off abscess
e. Gunshot wound to the abdomen with injuries to the small bowel and sigmoid colon
4.Which ONE of the following anaesthetic agents can cause malignant
hyperpyrexia? Please select one of the following:
A. Isoflurane
B. Halothane
C. Propofol
D. Sevoflurane ans
E. Ketamine
5.Which one of the following is a B cell neoplasm?
Non-Hodgkin’s lymphoma
Acute lymphoblastic leukemia
Burkitt’s lymphoma ans
Hodgkin’s disease
Histiocytosis X
6.A 33-year-old has an infection in pregnancy. Which of the following is a
reinfection, and therefore not a risk to the fetus?
a. Group B coxsackievirus
b. Rubella virus
c. Chickenpox virus
d. Shingles ans
e. Herpesvirus hominus type 2
7.Which of the following factors is most important in the subsequent
development of genital prolapse?
Poor tissue quality ans
Chronic straining at bowel movements
Menopause
Childbirth trauma
Multiple deliveries
8.Which of the following is not involved in enzyme regulation?
a) Covalent modification
b) Competitive inhibition
c) Suicide inhibition ans
d) Allosteric activation
9.Which of the following mutations is most likely to be lethal?
Substitution of adenine for cytosine
Substitution of cytosine for guanine
Substitution of methylcytosine for cytosine
Deletion of three nucleotides
Insertion of one nucleotide ans
10.Which of the following vaccines must NOT be given to a household contact of
an immune-deficient child?
a. Mumps, measles and rubella.
b. BCG.
c. Influenza vaccine.
d. Oral polio vaccine. ans
e. Hepatitis B vaccine.
11.Which of the following muscles given below lies in the posterior compartment
of the leg?
A. Fibularis Brevis
B. Fibularis Longus
C. Fibularis Tertius
D. Soleus ans
E. Tibialis Anterior
12.Which of the following structures lie within the
broad ligament?
A The fallopian tube ans
B The ureter
C The ovarian artery
D The superior vesical artery
13.The extraocular muscles are derived from which of the following structures?
(A) Branchial arches
(B) Optic cup ectoderm
(C) Somites
(D) Somitomeres ans
(E) Splanchnic mesoderm
14.The greater omentum is derived from which of the following embryonic
structures?
A. Dorsal mesoduodenum
B. Dorsal mesogastrium ans
C. Pericardioperitoneal canal
D. Pleuropericardial membranes
E. Ventral mesentery
15.Which of the following muscles is/are innervated by the pharyngeal plexus?
1. middle constrictor
2. tensor veli palatine ans
3. salpingopharygeus
4. internal (medial) pterygoid
16.The following strap muscles of the neck are innervated by the ansa cervicalis
1. omohyoid ans
2. sternohyoid
3. sternothyroid
4. thyrohyoid
17.Which of the following complications is unique for displaced femoral neck
fractures:
a. Infections.
b. Avascular necrosis. ans
c. Sciatic nerve injury.
d. Hypovolemic shock.
18.Which of the following is an appropriate initial treatment for pulmonary
tuberculosis?
(A) INH
(B) INH plus rifampin
(C) INH, rifampin, and ethambutol
(D) INH, rifampin, ethambutol, and pyrazinamide
(E) INH, rifampin, ethambutol, and streptomycin ans
19.Which of the following is a contraindication for usage of the drug
cyclophosphamide?
a. Liver disease ans
b. Lung disease
c. Heart disease
d. Hypertension
e. Diabetes
20.Which one of the following statements regarding DMRADs is true?
A. Has rapid onset of action
B. Have an immediate analgesic effect.
C. Slow the progress of the disease ans
D. They are the drugs of choice in gouty arthritis
E. They induce the formation of new cartilage.
21.Which of the following is wrong statements :
(A)Koilonychia in Vit B12 deficiency ans
(B)Oncholysis in Psoriasis
(C)Mees lines in Arsenic poisoning
(D)Pterygium of nails in Lichen Planus
22.Which of the following statements regarding carpal tunnel syndrome is
correct?
A.It is rarely secondary to trauma
B.It may be associated with pregnancy ans
C.It most often causes dysesthesia during waking hours
D.It is often associated with vascular compromise
E.Surgical treatment involves release of the extensor retinaculum
23.Which of the following statements concerning nasopharyngeal cancer is true?
A.It has an unusually high incidence among Chinese ans
B.It occurs primarily after the sixth decade of life
C.It undergoes early metastasis to the lungs
D.The treatment of choice is wide surgical excision of the primary tumor
E.Initial evaluation should involve a biopsy of the primary tumor and neck nodes
24.Which of the following enzymes can be described as a DNA-dependent RNA
polymerase?
a. DNA ligase
b. Primase,, (primarase) ans
c. DNA polymerase III
d. DNA polymerase I
e. Reverse transcriptase
25.Following enzymes could be targeted by allopurinol for the treatment of GOUT
patient?
A. Guanase
B. Hypoxanthine guanine phosphpribosyl transferase
C. Nuleotidase
D. Phosphoribosylpyrophosphate synthase
E. Xanthine oxidase ans
26.Microfilaments are made up of
a) actin ans
b) tubulin and actin
c) desmin
d) vimetin
27.A 20-year-old healthy man was diagnosed to have medullary cancer of the
thyroid. The patient was also noted to have hyperplasia of the parathyroid gland.
The patient must now be investigated for the possibility of :
a) Bowen's tumor
b) Hodgkin's lymphoma
c) Pheochromocytoma ans
d) Squamous cell carcinoma of the esophagus
e) Malignant melanoma
28.One day after a 10-km race, a previously healthy 42-year-old man has dark
urine. Urinalysis results are above. Which of the following is the most likely cause
of these findings?
a. Acute glomerulonephritis
b. Hypovolemia
c. Renal infarct
d. Renal vein thrombosis
e. Rhabdomyolysis ans
29.A 4 year old boy is brought in by his mother after she discovers that his urine
is now a dark coca-cola color. She reports that he was at the doctor 10 days ago
because he was complaining of a sore throat, but he has otherwise been well.
What is the most likely diagnosis?
a. Alport's syndrome
b. Goodpasture's syndrome
c. Henoch-Schonlein purpura
d. Minimal change disease
e. Post-streptococcal glomerulonephritis ans
Lysosomes are present in all except
a) muscle cells
b) acinal cells
c) erythrocytes ans
d) hepatocytes
30.From the following list select the 3 tumour markers that are of clinical use in
the "work up" of a patient with an unknown suspected primary malignancy: (e.g.
weight loss/ malaise)
a. Beta HCG
b. CA 19-9
c. AFP (alfa fetoprotein) ans
d. CA 153
e. Thyroglobulin
f. PSA (prostate specific antigen)
g. CA125
31.Which of the following ions are required for binding of ribosomal subunits
a) Na+
b) Mg++ ans
c) Mn++
d) Fe++
32.Primary lymphoid organs include
a) Thymus and spleen
b) Thymus and bone marrow ans
c) Thymus, bone marrow and spleen
d) Thymus, bone marrow, spleen and lymph nodes
33.A 6-year-old boy presents to the emergency room complaining of nausea and
a new-onset rash that developed shortly after ingesting a peanut. Which of the
following antibodies is most likely responsible for the type of reaction this boy is
now experiencing?
a. IgA
b. IgD
c. IgE ans
d. IgG
e. IgM
34.The application of statistical methods in biology is called
a) Statistics in biology
b) statistic in vivo
c) biostatistics ans
d) all of these
35.Recombinant DNA human health care product developed for treating
haemophiliacs is
a) interferon
b) lymphokines
c) coaglutation factor IX ans
d) phytohemaglutinin
36.The number of types of gametes produced by a heterozygous individual is
a) 1
b) 2 ans
c) 3
d) many
37.DNA synthesis can be specifically measured by estimating the incorporation
of radio labelled
a) uracil
b) thymine ans
c) Adenine
d) Deoxyribose sugar
39.Chromosome is thickest during
a) prophase
b) metaphase ans
c) anaphase
d) interphase
40.Chromatin has
a) DNA
b) DNA and proteins
c) DNA, RNA and proteins ans
d) none of these
41.The haploid set of the chromosomes is called as
a) proteome
b) genomics
c) genome ans
d) genes
42.Eukaryotic flagella is driven by
a) ATP ans
b) proton
c) both a and b
d) none of these
43.Which of the following is the function of lysosomes
a) autophagy
b) autolysis
c) digestion
d) all of these ans
44.Which of the following is not a diseases associated with lysosome
malfunctioning
a) Tay-Sachs disease
b) I-cell disease
c) Pompe’s disease
d) Marfan syndrome ans
45.The major amino acids in histones are
a) Gluatamate and aspartic acid
b) lysine and arginine ans
c) arginine, lysine and histidine
d) histidine
46.Injection of anti-venom to a patient for snake bite is an example of
a) Naturally acquired active immunity
b) Artificially acquired active immunity
c) Naturally acquired passive immunity
d) Artificially acquired passive immunity ans
47.All the following comes under non-specific defence mechanism except
a) fever
b) phagocytes
c) cell mediated immunity ans
d) complement system
48.
Unwinding of DNA is done by
a) Helicase ans
b) ligase
c) Hexonuclease
d) Topoisomerase
49. A 37-year-old female presents to the emergency room with a fever. Chest xray shows multiple patchy infiltrates in both lungs. Echocardiography and blood
cultures suggest a diagnosis of acute bacterial endocarditis limited to the
tricuspid valve. Which of the following is the most probable etiology?
A. Congenital heart disease
B. Illicit drug use ans
C. Rheumatic fever
D. Rheumatoid arthritis
E. Systemic lupus erythematosus
50. Which of the following organelle is involved in lipid metabolism?
a) Golgi apparatus
b) Peroxisomes
c) SER ans
d) RER