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Course Code :GBE 305 Course Title : MOLECULAR BIOLOGY II Level : Undergraduate Year : III Status : Compulsory Hours/Week : 5 Semester : V ECTS Credits : 5 Total Hours : 75 Instructor : COURSE DESCRIPTION The course covers advanved topics on molecules, energy, and biosynthesis, macromolecules (structure, shape, and information), how cells are studied, protein function, basic genetic mechanisms, recombinant DNA technology, and control of gene expression etc COURSE OBJECTIVES Students will move beyond their introductory textbooks towards a deeper understanding of modern molecular biology. COURSE CONTENTS Chemistry and structure of DNA Chromosomes, Chromatin and nucleosome The replication, mutability and repair of DNA Homologous recombination Site specific recombination and transposition of DNA Mechanism of transcription, RNA splicing Translation, the genetic code Gene regulation in prokaryotes Gene regulation in eukaryotes’ Gene regulation during development etc. Genomics and Systems Biology Techniques in Molecular Biology Model Organisms TEACHING/ASSESSMENT Description Teaching Methods 1. Interactive 2. Discussions and group works 3. Tutorials and Labs The goal is to maximize student’s participation in all teaching methods. Description(%) Student Assessment Methods Learning Outcomes Quizzes Homework Project Midterm Examination Final Examination Language of Instruction Textbook(s) 10% 10% 20% 20% 40% Actively participate in courses and begin to take responsibility for learning Begin to work effectively as part of a team, developing interpersonal, organisational and problem-solving skills within a managed environment, exercising some personal responsibility. Present information in oral, written or graphic forms in order to communicate effectively with peers and tutors. English 1) 2) Molecular Biology of the Cell Bruce Alberts, Alexander Johnson, Julian Lewis, Martin Raff, Keith Roberts Peter Walter Cell and Molecular Biology: Concepts and Experiments (Karp, Cell and Molecular Biology) Gerald Karp