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CV summary Title & full name: Professor Vincenzo Valentini Profession: Radiation Oncologist Institute, city, country: Radiation Oncology Department – Gemelli-ART Università Cattolica S.Cuore Rome, Italy Contact details: Largo Agostino Gemelli 8, 00168 Roma T +39 06 3015 6054/5226 F +39 06 35501928 C +39 339 1181736 [email protected] www.gemelli-art.it Qualifications / education: Full Professor in Radiation Oncology Chairman of Radiation Oncology Department Medical Doctor and Specialist in Radiation Oncology, Radiology and Sperimental Oncology Main areas of professional interest / specialisation In the past 30 years he focused his activity exclusively in Radiotherapy directing his interest to all its different fields. Particularly he focused on: the optimization of radiation treatments by using different imaging techniques for the definition of target volume delineation guidelines; integration between radiotherapy and surgery, in which he collaborated for the conduction of pre-operative and intra-operative programs; integration between radiotherapy and chemotherapy, in which he applied different schedules for the treatment of locally advanced neoplasm especially in GI, GU, Lung and H&N. He implemented a Quality Assurance Program in the Radiation Oncology Department, accredited by the American College of Radiation Oncology, since 2002. He also directed his interest on the computer’s application in the fields of care, research and teaching. He promoted in the 80’ a telematics system for clinical consultation in the Italian oncological scenario (TELECOS project); tutorials for delineation of target volume (TIGER and FALCON by ESTRO); on line dissemination of ESTRO knowledge repository (DOVE, EAGLE). Over the past years he worked on the realization of different clinical medical record systems to easier the clinical management of patients and data mining. Recently opened two Knowledge Based Oncology laboratories for research in large data base data mining and Radiomics. Professional experience / appointments: His professional experience and appointments were at the Radiation Oncology Department of the Università Cattolica S.Cuore – Rome 1979 1980 1983 1985 1985 1988 2003 2006 Medical Doctor Degree Clinical Assistant Radiotherapy Residency Assistant Professor in Radiation Oncology Radiology Residency Oncology Residency Associate Professor in Radiation Oncology Clinical Chairman of Radiation Oncology 2012 2014 Chairman of Department Radiation Oncology Full Professor in Radiation Oncology Research interests: imaging techniques for the definition of target volume delineation guidelines integration between radiotherapy and surgery in the pre-operative and intraoperative programs integration between radiotherapy and chemotherapy, in GI, GU, Lung and H&N large data base data mining and Radiomics Professional membership & associations: He is member of: AIRO (Associazione Italiana di Radioterapia Oncologica), ESTRO (European SocieTy for Radiotherapy & Oncology), American Radium Society, ASTRO (American Society of Radiation Oncology), ISIORT (International Society of Intraoperative Radiotherapy) and ESMO (European Society of Medical Oncology). He was the general secretary of ISIORT (International Society of Intraoperative Radiotherapy) from 2000 to 2011, member of the Core group of the ESTRO Educational and Training Committee, he is director of the ESTRO teaching Course on Evidence and research on Rectal Cancer and ESTRO-ESOR Course on Multidisciplinary Approach of Cancer Imaging. He served as President of ESTRO from 2011 to 2014. He promoted multidisciplinary guidelines within EURECCA consortium. Honours and awards: 2010 Acta Oncologica Lecture 2012 DR. K A DINSHAW ORATION, AROI (Association of Radiation Oncologists of India) 2012 Honorary Membership from European Society of Surgical Oncology (ESSO) 2013 Honorary Membership from Societad Espanola de oncologia Radioterapica (SEOR) 2014 Vera Peters -Ray Bush Professor lecture (Princess Margaret Cancer Centre, Toronto, Canada) 2014 Honorary Member of Japanese Society for Radiation Oncology (JASTRO) Top most international scientific publications / books: He is author of more than 350 publications, books and chapters. Some of them are: ESTRO 2012 strategy meeting: vision for radiation oncology. Radiother Oncol. 2012 Apr;103(1):99-102. Involving patients in a multidisciplinary European consensus process and in the development of a 'patient summary of the consensus document for colon and rectal cancer care'. Patient. 2014;7(3):261-70. Policy statement on multidisciplinary cancer care. European Partnership Action Against Cancer consensus group, Eur J Cancer. 2014 Feb;50(3):475-80. Still a long way to go to achieve multidisciplinarity for the benefit of patients: commentary on the ESMO position paper (Annals of Oncology 25(1): 9-15, 2014). Ann Oncol. 2014 Sep;25(9):1863-5. EURECCA colorectal: multidisciplinary management: European consensus conference colon & rectum. Eur J Cancer. 2014 Jan;50(1):1.e1-1.e34. Tumor regression grading in rectal cancer: is it time to move forward? J Clin Oncol. 2014 May 20;32(15):1534-6. Long-term outcome in patients with a pathological complete response after chemoradiation for rectal cancer: a pooled analysis of individual patient data. Lancet Oncol. 2010 Sep;11(9):835-44 Nomograms for predicting local recurrence, distant metastases, and overall survival for patients with locally advanced rectal cancer on the basis of European randomized clinical trials. J Clin Oncol. 2011 Aug 10;29(23):3163-72. Development and external validation of a predictive model for pathological complete response of rectal cancer patients including sequential PET-CT imaging. Radiother Oncol. 2011 Jan;98(1):126-33. Quality assurance in the treatment of colorectal cancer: the EURECCA initiative. Ann Oncol. 2014 Aug;25(8):1485-92. Transanal endoscopic microsurgery after neoadjuvant radiochemotherapy for locally advanced extraperitoneal rectal cancer: short-term morbidity and functional outcome. Surg Endosc. 2013 Aug;27(8):2860-7. Preoperative hyperfractionated chemoradiation for locally recurrent rectal cancer in patients previously irradiated to the pelvis: A multicentric phase II study. Int J Radiat Oncol Biol Phys. 2006 Mar 15;64(4):1129-39. Multidisciplinary Management of Rectal Cancer. Springer-Verlag (ISBN 978-3-642-25004-0) (ISBNeBook 978-3-642-25005-7) , Berlin Heidelberg, 2012 An umbrella protocol for standardized data collection (SDC) in rectal cancer: A prospective uniform naming and procedure convention to support personalized medicine. Radiother Oncol. 2014 May 19. pii: S0167-8140(14)00171-6. 'Rapid Learning health care in oncology' - an approach towards decision support systems enabling customised radiotherapy'. Radiother Oncol. 2013 Oct;109(1):159-64. The future of predictive models in radiation oncology: from extensive data mining to reliable modeling of the results. Future Oncol. 2013 Mar;9(3):311-3. International data-sharing for radiotherapy research: an open-source based infrastructure for multicentric clinical data mining. Radiother Oncol. 2014 Feb;110(2):370-4. Predicting outcomes in radiation oncology--multifactorial decision support systems. Nat Rev Clin Oncol. 2013 Jan;10(1):27-40. Clinical validation of atlas-based auto-segmentation of pelvic volumes and normal tissue in rectal tumors using auto-segmentation computed system. Acta Oncol. 2013 Nov;52(8):1676-81. Four years with FALCON - An ESTRO educational project: Achievements and perspectives. Radiother Oncol. 2014 Jul 25. pii: S0167-8140(14)00285-0. Competencies in radiation oncology: a new approach for education and training of professionals for Radiotherapy and Oncology in Europe. Radiother Oncol. 2012 Apr;103(1):1-4 Multi-institutional Pooled Analysis on Adjuvant Chemoradiation in Pancreatic Cancer. Int J Radiat Oncol Biol Phys. 2014 Sep 11. pii: S0360-3016(14)03531-7. doi Role of microRNA in response to ionizing radiations: evidences and potential impact on clinical practice for radiotherapy. Molecules. 2014 Apr 24;19(4):5379-401. Analysis of intraprostatic failures in patients treated with hormonal therapy and radiotherapy: implications for conformal therapy planning. Int J Radiat Oncol Biol Phys. 2002 Jul 1;53(3):595-9. Analysis of intraprostatic failures in patients treated with hormonal therapy and radiotherapy: implications for conformal therapy planning. Int J Radiat Oncol Biol Phys. 2002 Jul 1;53(3):595-9. Survival after radiotherapy in gastric cancer: systematic review and meta-analysis. Radiother Oncol. 2009 Aug;92(2):176-83 The role of proton therapy in the treatment of large irradiation volumes: a comparative planning study of pancreatic and biliary tumors. Int J Radiat Oncol Biol Phys. 2000 Aug 1;48(1):277-88. Hobbies: Rome history and art Enjoying nature, family and friends Personal statement (optional): You see things; and you say 'Why?' But I dream things that never were; and I say 'Why not?' George Bernard Shaw