Download Senior Scientist I, Purification, Process Sciences

Senior Scientist I, Purification, Process Sciences
Description
Overview:
A Senior Scientist position is available within Purification group in Process Sciences Department at AbbVie
Bioresearch Center in Worcester. The group is responsible for developing and supporting downstream manufacturing
process for early and late phase clinical biologics programs. We strive for speedy delivery of high quality processes
that are high yield with desirable product qualities, cost-effective, manufacturing friendly, and robust. The group
interacts closely with Cell Culture Development, Pilot Lab, and Protein Analytics within the department, and Drug
Product Formulation Development, Manufacturing, Quality, CMC, and Discovery outside the department. We are
seeking an enthusiastic, creative scientist who will make tangible contribution to the continuous improvement and
innovation within the organization.
Key responsibilities:
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Develop recovery and purification process that utilizes clarification, chromatography, and membrane
filtration technologies for recombinant proteins
Design and execute innovative process development and characterization activities, impurity and viral
clearance studies
Is responsible for technology transfer to manufacturing facilities, troubleshooting and investigation activities
Address and solve technical problems independently, conceive and implement innovative process research
ideas, evaluate and integrate state-of-the-art technology to improve process, and demonstrate a high level
of scientific initiative
Author technical report, support and contribute to regulatory filings
Provide project update and analysis to cross-functional team and senior management
Present original work internally across departments and at external conferences
May author or co-author peer-reviewed scientific papers or patents
Basic:
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PhD degree in chemical engineering or biochemical engineering or related disciplines
0-3 years of experiences in protein purification process development and/or manufacturing support
Sound scientific understanding of current protein separation technologies and ability to explore and develop
new approaches to further advance innovative purification technologies desirable
Basic knowledge in related functional areas, such as cell culture, protein chemistry and analytics or
formulation, a plus
Demonstrated record of independent thought, creativity and scientific accomplishment (e.g. peer reviewed
journal publications, patents)
Candidate must be a goal oriented team player with excellent verbal and written communication skills