Download bt 6602 immunology dr.r.b.narayanan

FT/GN/68/01/23.01.16
SRI VENKATESWARA COLLEGE OF ENGINEERING
COURSE DELIVERY PLAN - THEORY
Page 1 of 6
Department of Biotechnology
LP: Sub Code BT6602
B.E/B.Tech/M.E/M.Tech : Biotechnology (VI Semeter)
PG Specialisation
: Biotechnology
Sub. Code / Sub. Name
: BT 6602 / Immunology
Unit
: I INTRODUCTION
Regulation: 2013
Rev. No: 00
Date: 29/12/2016
(9 Hrs)
Unit Syllabus: INTRODUCTION
Cells of immune system. Innate and Acquired immunity. Primary and Secondary lymphoid organs. Antigens Chemical and Molecular nature, Haptens, Adjuvants, Types of immune responses, Antigen processing and
presentation. Theory of clonal selection. Monoclonal antibodies – Principles and Applications.
Objective: To know about the immune system
Session
No *
Topics to be covered
1
Introduction to immunology
2
Cells of immune system
3
Innate and acquired immunity
4
Ref
Teaching Aids
PPT & BB
T1(1-19),
T2(30-40)
T1(21-36)
T2 (7-16)
PPT, Video & BB
Primary and secondary lymphoid organs
T1(147-162),
T2(40-43)
PPT, Video & BB
5
Antigens: chemical and molecular nature
T2 ( 77-81)
PPT, Video & BB
6
Haptens and Adjuvants
T1(80-83),
T1(300-302),
T2 (77-78,81)
PPT, Video & BB
7
Types of immune responses
T2(448-454)
PPT & BB
8
Theory of clonal selection
T2(16-18)
PPT, Video & BB
9
Review
-
-
PPT & BB
Content beyond syllabus covered (if any) : Immunogenicity, Antigenicity, Immuno diffusion and
Immunoelectrophoresis
* Session duration: 50 minutes
FT/GN/68/01/23.01.16
SRI VENKATESWARA COLLEGE OF ENGINEERING
COURSE DELIVERY PLAN - THEORY
Page 2 of 6
Sub. Code / Sub. Name: BT 6602 / Immunology
Unit : II CELLULAR RESPONSES
(9 Hrs)
Unit Syllabus: CELLULAR RESPONSES
Development, maturation, activation and differentiation of T-cells and B-cells. TCR. Antibodies - Structure and
Functions. Antibodies - Genes and Generation of diversity. Antigen-Antibody reactions. Antigen presenting
cells. Major histocompatibility complex. Regulation of T-cell and B-cell responses.
Objective: To study about the cellular responses of immune system
Session
No *
10
Introduction to cellular responses
T2(11-14)
PPT, Video & BB
11
Development, maturation of T-cells and B-cells
T1(164-174),
T2(245-257)
PPT & BB
12
Activation, differentiation of T-cells and B-cells
T1(164-174),
T2(245-257)
PPT, Video & BB
13
T-Cell Receptor
Antibodies: structure and functions
Antigen-antibody reactions
T2(223-241)
PPT, Video & BB
T1(37-58), T2(84100) T2(145-164)
14
Antibodies: genes and generation of diversity
T1(37-58),
T2(111-135)
PPT & BB
15
Monoclonal antibodies, principles and applications
T1(84,120-125),
T2(104-107,136)
PPT, Video & BB
16
T2(207-2115)
T2(206-209)
T1(70-77),
T2(189-205)
PPT, Video & BB
17
Antigen presenting cells & Major histocompatibility
complex
Antigen processing and presentation
18
Regulation of T-cell & B-cell responses.
T1(173-183),
T2(15,16)
T2 (292-297)
PPT & BB
Topics to be covered
Content beyond syllabus covered (if any):
* Session duration: 50 mins
Ref
Teaching Aids
PPT & BB
FT/GN/68/01/23.01.16
SRI VENKATESWARA COLLEGE OF ENGINEERING
COURSE DELIVERY PLAN - THEORY
Page 3 of 6
Sub. Code / Sub. Name: BT 6602 / Immunology
(12 Hrs)
Unit : III INFECTION AND IMMUNITY
Unit Syllabus: INFECTION AND IMMUNITY
Injury and inflammation. Immune responses to infections. Immunity to virus, bacteria, fungi and parasites.
Cytokines, Complement, Immunosuppression and Tolerance. AIDS and Immunodeficiency Diseases. Resistance
and immunization. Vaccines.
Objective: To learn about infection and immune responses to an antigen, immunodeficiency and vaccines
Session
No *
Topics to be covered
Ref
Teaching Aids
19
Injury and inflammation
T2(327-346)
PPT & BB
20
Immune responses to infections
T2(258)
PPT, Video & BB
21
Immunity to viruses and bacteria
T2(447-470)
PPT & BB
22
Immunity to fungi and parasites
T2(447-470)
PPT & BB
23
Cytokines
T2(302-321)
PPT, Video & BB
24
Complement
T2(168-185)
PPT, Video & BB
25
Immunosuppression and tolerance
T2(402-416)
PPT, Video & BB
26
Immunosuppression and tolerance
T2(402-416)
PPT, Video & BB
27
AIDS
T2(493-518)
PPT, Video & BB
Immunodeficiencies
T2(493-518)
PPT & BB
28
Resistance
and
immunisation
T2(476-480)
PPT & BB
29
Vaccines.
T2(475-488)
PPT & BB
30
Content beyond syllabus covered (if any): Host defense mechanism and escape mechanism of microbes to
immune responses
* Session duration: 50 mins
FT/GN/68/01/23.01.16
SRI VENKATESWARA COLLEGE OF ENGINEERING
COURSE DELIVERY PLAN - THEORY
Page 4 of 6
Sub. Code / Sub. Name: BT 6602 / Immunology
Unit : IV TRANSPLANTATION AND TUMOR IMMUNOLOGY
(8 Hrs)
Unit Syllabus: TRANSPLANTATION AND TUMOR IMMUNOLOGY
Transplantation - Genetics of transplantation and Laws of transplantation. Tumor immunology, Tumor antigens,
Tumor immune response, Tumor diagnosis and Tumor immunotherapy.
Objective: To learn about Tumor immunology
Session
No *
31
32
33
34
35
Topics to be covered
Ref
Teaching Aids
Introduction to transplantation
T2(425-439)
PPT, Video & BB
Genetics of transplantation
T2(440-443)
PPT & BB
Genetics of transplantation
T2(440-443)
PPT & BB
Laws of transplantation
T2(440-443)
PPT, Video & BB
Introduction to tumor immunology
T1(374-395)
T2(525-545)
PPT, Video & BB
Tumor immunology related to clinical aspects
T1(374-395)
T2(525-545)
PPT & BB
Tumor immunology
T1(374-395)
PPT & BB
Review
-
-
36
37
38
Content beyond syllabus covered (if any): Apoptosis, Transgenic mice, Gene knock outs
* Session duration: 50 mins
FT/GN/68/01/23.01.16
SRI VENKATESWARA COLLEGE OF ENGINEERING
COURSE DELIVERY PLAN - THEORY
Sub. Code / Sub. Name: BT 6602 / Immunology
Unit : V ALLERGY, HYPERSENSITIVITY AND AUTOIMMUNITY
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(7 Hrs)
Unit Syllabus: ALLERGY, HYPERSENSITIVITY AND AUTOIMMUNITY
Allergy and Hypersensitivity - Types of Hypersensitivity. Autoimmunity, Autoimmune Disorders and Diagnosis
Objective: To learn Autoimmunity
Session
No *
39
40
41
42
43
44
45
Topics to be covered
Introduction to autoimmunity
Types of Hypersensitivity – Type I & II
Ref
T1( 396-420)
T2(407- 416)
T2(371-396),
T1(322-347)
Types of Hypersensitivity – Type III & IV
T2(371-396),
T1(322-347)
Autoimmunity
T1 420
Autoimmune disorders
T1(421- 448)
Autoimmune disorders and diagnosis
T1(421- 448)
Review
-
Teaching Aids
PPT & BB
PPT, Video & BB
PPT, Video & BB
PPT & BB
PPT, Video & BB
PPT & BB
Content beyond syllabus covered (if any): Rheumatoid Arthritis, Myasthenia Gravis, Systemic Lupes.
* Session duration: 50 mins
-
FT/GN/68/01/23.01.16
SRI VENKATESWARA COLLEGE OF ENGINEERING
COURSE DELIVERY PLAN - THEORY
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REFERENCES:
TEXT BOOKS:
1.Roitt I, Male, Brostoff.” Immunology”, Mosby Publ., 12th edition, 2011.
2.Kuby J, “Immunology”, WH Freeman & Co., 7th Edition, 2012.
3.Ashim K. Chakravarthy, “Immunology”, Tata McGraw-Hill, 2006.
REFERENCES:
1.Coico, Richard, “Immunology: A Short Course”, 7th Edition. John Wiley, 2015.
2.Khan, Fahim Halim, “Elements of Immunology”, Pearson Education, 2009.
Prepared by
Approved by
Prof. R. B. Narayanan
Prof. Dr. E.Nakkeeran
PROFESSOR
HEAD OF THE DEPARTMENT /BT
29.12.2016
29.12.2016
Signature
Name
Designation
Date
Remarks *:
Remarks *:
* If the same lesson plan is followed in the subsequent semester/year it should be mentioned
and signed by the Faculty and the HOD