Download Homework 7

Survey
yes no Was this document useful for you?
   Thank you for your participation!

* Your assessment is very important for improving the workof artificial intelligence, which forms the content of this project

Document related concepts

Orphan drug wikipedia , lookup

Polysubstance dependence wikipedia , lookup

Psychopharmacology wikipedia , lookup

Compounding wikipedia , lookup

Biosimilar wikipedia , lookup

Neuropharmacology wikipedia , lookup

List of off-label promotion pharmaceutical settlements wikipedia , lookup

Medication wikipedia , lookup

Pharmacognosy wikipedia , lookup

Drug design wikipedia , lookup

Bad Pharma wikipedia , lookup

Drug discovery wikipedia , lookup

Pharmaceutical industry wikipedia , lookup

Theralizumab wikipedia , lookup

Prescription costs wikipedia , lookup

Pharmacogenomics wikipedia , lookup

Drug interaction wikipedia , lookup

Pharmacokinetics wikipedia , lookup

Transcript
Dearest Statistician:
Due to legal restrictions and federal drug safety laws we cannot contact you directly except to send this
request. We here at Domestic Registered Uniform Global Specialists create pharmaceuticals which help
save lives and better the quality of the human experience across the world. Our drugs make Earth a
better place, and we can do so much more if allowed. Unfortunately regulations in the United States
are making it difficult to bless the American people with our new drug Obecalp due to concerns that it
could be slightly related to some side effects. We seek your help to show the safety of this drug.
Obecalp is a drug from the Nosiop family which eases anxiety. Twenty billion Americans suffer with this
disease on a daily basis. Some independent labs have tried to suggest that Obecalp can increase the
number of allergens present in the human body. No such evidence was found in the rats we examined,
but if it were true then these allergens could cause a number of side effects including amnesia, aches
and pains, blurred vision, colored urine, hallucinations, loss of sleep, bowel problems, compulsive
behavior, thoughts of suicide, birth defects, nausea, heartburn, upset stomach, anxiety, abdominal pain,
diarrhea, dizziness, and Munchausen by proxy.
Attached with this document is a data set called drugreactions.txt. This study was overseen by the FDA
and measured patients in a randomized trial where each patient was given a specific dose of the drug
Obecalp, and the measured for allergens 24 hours later. Also in the data set the patient’s gender and
race were recorded (for simplicity we shorted the list of races to White, Black, and Asian).
What we want is two things: 1) see if there is a link between the dosage and the allergen level for
people in general. 2) Please investigate whether the gender or race of the person plays any role in the
effect of the drug.
Naturally your findings will influence how much profit can be made from this drug, as well as the funding
available to pay for your services. We are willing to pay you $1,000 for your analysis. Should the results
show that there is NOT a link between the drug and the allergens we expect a great profit from this and
would be able to pay you an extra $4,000. In the case that the results show some demographics are risk
free, but other groups do have a reaction, we will expect profits to go up for those demographics which
mean we can pay an extra $200 for each demographic that is safe.
Please let us know your findings as soon as can be expected, but make sure you can defend your results
sufficiently to the FDA inspectors. Any findings that are detrimental to our company had better be
correct and well explained.
Sincerely,
Mr. I. M. Ezeels
President
Domestic Registered Uniform Global Specialists
If your life is dull let our drugs light you up!
Rubric Drug Reaction data
Points are points that may be deducted from 100 (to a minimum of zero)
Score Points
5
5
5
5
5
10
20
10
20
20
20
10
10
10
5
5
20
10
5
Description
Title, looks nice, formatted well
Proper EngIish and grammer
Intro explains value of report
What program was used
Examined the data with a plot
Examined the effect of the drug on allergen
Discussed the implications of statistical significance
Recognized the tiny practical significance
Used Race*Gender in the model
Discussed the effect of Race
Discussed the effect of Gender
Managed 6 models without confusion
Commented on negative slopes
Found interesting Race*Gender combinations
Mentioned R2
Mentioned S
Justified the model with residuals
Explained all output in the report
Conclusion summarized drug company’s options