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ACCESSORY EYE STRUCTURES

Eyebrows
◦ Shade
◦ Protection from sweat
and other substances
 Eyelids (Palpebrae)
 Protection from foreign
objects
 Moisten the eyes
(blinking)
 Levator palpebrae
superioris muscles
raise the eyelids
 Palpebral Fissure
 Space between upper and
lower eyelids
ACCESSORY EYE STRUCTURES

Medial and Lateral
Canthi
◦ Eye angles
 Caruncle
 Fleshy, elevated area
in medial canthus
 Contains sebaceous
and sweat glands
 Eyelashes
 Reflex blinking when
touched
 Richly innervated
ACCESSORY EYE STRUCTURES

Tarsal or Meibomian
Glands
◦ Embedded in eyelids
◦ Openings posterior to
eyelashes
◦ Secrete oil to lubricate
eyelids
 Ciliary Glands
 Small sebaceous
glands
 Between hair follicles
of eyelashes
ACCESSORY EYE STRUCTURES

Conjunctiva
◦ Mucous membrane
◦ Lines inside of each
eyelid (palpebral
conjunctiva)
◦ Covers anterior
surface of eye except
over cornea (bulbar or
ocular conjunctiva)
palpebral
conjunctiva
ocular
conjunctiva
ACCESSORY EYE STRUCTURES

Lacrimal Apparatus
lacrimal gland
◦ Lacrimal gland + ducts that lacrimal sac
drain tears into nasal cavity
◦ Releases dilute saline
solution onto eyes
 Contains mucus,
lacrimal
antibodies, lysozyme
canal
◦ Solution drains via:
nasolacrimal
 Lacrimal puncta 
duct
lacrimal canals  lacrimal
sac  nasolacrimal duct
 nasal cavity
EXTRINSIC EYE MUSCLES

Superior Rectus
◦ Moves eyes superiorly
 Inferior Rectus
 Moves eyes inferiorly
 Lateral Rectus
 Moves eyes laterally
 Inferior Oblique
 Moves eyes up and
out
[R] Lateral View
EXTRINSIC EYE MUSCLES
 Superior Oblique
 Moves eyes down
and out
 Medial Rectus
 Moves eyes medially
Superior View
EYE MUSCLE INNERVATION

(LR6SO4)O3
Lateral Rectus
Superior Oblique
All Others
Cranial nerve VI (abducens)
Cranial nerve IV (trochlear)
Cranial nerve III (oculomotor)
Name
Cranial Nerve
Action
Lateral rectus
VI (abducens)
Moves eye laterally
Medial rectus
III (Oculomotor)
Moves eye medially
Superior rectus
III (Oculomotor)
Moves eye superiorly
Inferior rectus
III (Oculomotor)
Moves eye inferiorly
Inferior oblique
III (Oculomotor)
Moves eye up and out
Superior oblique
IV (trochlear)
Moves eye down and out
STRUCTURE of the EYE
FIBROUS TUNIC
Sclera
Cornea
STRUCTURE of the EYE
VASCULAR TUNIC
Ciliary body
Iris
Choroid
STRUCTURE of the EYE
SENSORY TUNIC
Outer
Retinapigmented
Inner
neural layer
STRUCTURE OF THE EYE
Ora serrata
Suspensory
ligament
Cornea
Pupil
Iris
Ciliary body
Sclera
Choroid
STRUCTURE of the EYE
Anterior
Segment
Posterior chamber
Anterior chamber
Lens
Vitreous humor
STRUCTURE of the EYE
Optic disc
Optic nerve
Optic disc
Fovea centralis
Macula lutea
STRUCTURE of the EYE
Canal of Schlemm
Central artery & vein
PHYSIOLOGY OF VISION: REFRACTION

Refraction
◦ Bending of light rays
◦ Light rays change speed as they pass through
substances of different densities
◦ Light is refracted in 3 areas of the eye:
 Cornea
 Entrance of lens
 Exit of lens
Distant vision
Close vision
PHYSIOLOGY OF VISION: REFRACTION
lens bulges

Lens shape can
change
◦ Can be used to refract
light to a specific
distance
◦ Allows light to focus on
retina
◦ No focusing is
necessary for distant
objects (over 6m away)
Close vision
lens flattens
Distant vision
FOCUSING FOR NEAR VISION

Accommodation

Constriction of Pupils

Convergence of Eyeballs
◦ Ciliary muscle contracts
◦ Suspensory ligaments release tension on lens
◦ Lens thickens and bulges to focus image on
retina
◦ Constrictor muscle in iris makes pupil smaller
◦ Focuses light in a finer point
◦ Medial rectus muscles contract
◦ Each eye moves medially
◦ Focuses on near object
VISION: DISORDERS OF REFRACTION
 Emmetropia
◦ Normal vision
 Myopia
 Nearsightedness
 Object focuses in front
of the retina
 Eyeball is too long
 Hyperopia
 Farsightedness
 Object focuses behind
the retina
 Eyeball is too short
PHOTORECEPTION: THE RETINA

Pigmented Layer
◦ Outer layer of retina
◦ Dark pigment to
prevent light from
scattering
 Neural Layer
pigmented
layer
neural layer
 Inner layer of retina
 Contains photoreceptors
Modified neurons called
rods and cones
 Composed of three layers
THE RETINA: INNER NEURAL LAYER

Three Layers
◦ Photoreceptor
layer
 Bipolar cell layer
 Ganglion cell
layer
THE RETINA: INNER NEURAL LAYER

Photoreceptor Layer
◦ Rods and cones adjacent
to the outer pigmented
layer
 Rods
cone
More numerous
rod
Used in dim light
Used for peripheral
vision
Do not detect color
 Cones
Less numerous
Provide color vision
Used for acute vision
Light
NEURAL LAYER: RODS AND CONES

Rods and Cones
◦ Contain an inner and
outer segment
◦ Outer segment
 Receptor region
 Contains visual
pigments
inner segment
outer segment
NEURAL LAYER: BIPOLAR CELLS

Bipolar Cells
◦ Just inside the
photoreceptor cell region
◦ Pass impulse from the
receptor cells to the inner
ganglion cells
Light
NEURAL LAYER: GANGLION
CELLS

Ganglion Cells
◦ Innermost retinal layer
◦ Generate an action potential in
response to photoreceptor and
bipolar cells
◦ Action potential travels to optic
nerve (composed of axons from
these cells)
Light
VISUAL PIGMENTS

Retinal
◦ Light absorbing molecule
◦ Made from Vitamin A
◦ Combines with proteins call opsins to form 4
types of visual pigments
◦ When bound to opsin, retinal is bent
◦ When light strikes retinal it causes the
molecule to straighten and release opsin
◦ Series of reactions result in electrical
impulses down the optic nerve
PHOTODISSOCIATION OF
RHODOPSIN
Retinal
1
4
2
Rhodopsin
3
Energy
Light
active
site
STIMULATION OF PHOTORECEPTORS

Excitation of Rods
◦ Visual pigment in rods is rhodopsin (retinal + a
form of opsin)
◦ Stored in discs in outer segments of rods
◦ Light strikes rhodopsin  retinal changes shape
 releases opsin
◦ Triggers a reaction that initiates an impulse
◦ Retinal is converted back to its original form in
the pigmented layer of the retina
◦ Rhodopsin is reformed when the retinal attaches
to opsin again
STIMULATION OF
PHOTORECEPTORS

Excitation of Cones
◦ 3 types of Cones
Each contains a pigment with a different opsin
Each pigment is sensitive to a different wavelength of light
Each detects a different color of light (red, green and blue)
Breakdown and regeneration of visual pigments in the cones
is the same as for rhodopsin
 Threshold for activation of cones is much higher so they
respond to intense light




VISION DISORDERS

Night Blindness
◦ Nyctalopia
◦ Caused by impairment of rod function
◦ Most commonly caused by Vitamin A deficiency

Color Blindness
◦ Due to lack of one or more cone types at birth
◦ Most commonly red/green color blindness
VISUAL PATHWAY
Right
eye
Left
eye
Optic nerve
Optic chiasma
Optic tract
Lateral geniculate
body of thalamus
Optic radiations
Visual cortex