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Name /bks_53161_deglins_md_disk/glycerin 02/14/2014 02:13PM Plate # 0-Composite pg 1 # 1 Adverse Reactions/Side Effects CNS: confusion, headache. GI: diarrhea, cramping, nausea, vomiting. F and E: dehydration. Misc: thirst. 1 glycerin (gli-ser-in) Fleet Babylax, Sani-Supp Classification Therapeutic: antiglaucoma agents, laxatives Pharmacologic: osmotics Pregnancy Category C Interactions Drug-Drug: None known. Route/Dosage Laxative Rect (Adults and Children ⬎6 yr): 1 adult suppository 1– 2 times/day as needed or 5– 15 mL as an enema. Rect (Children ⬍6 yr): 1 infant suppository 1– 2 times/day as needed or 2– 5 mL as an enema. Indications Rect: Treatment of constipation. Ophth: Reduction of corneal edema. Action Draws water into the lumen of the colon. Osmotically draws water from extravascular spaces, including the eye, into intravascular compartment. Therapeutic Effects: Relief of constipation. Reduction of corneal edema. Reduction of Corneal Edema Pharmacokinetics Absorption: Not significantly absorbed from colonic mucosa. Distribution: Remains in the intravascular space. Metabolism and Excretion: 80% metabolized by the liver, 10– 20% metabo- NURSING IMPLICATIONS Assessment lized by the kidneys. Half-life: 30– 45 min. TIME/ACTION PROFILE ● Assess color, consistency, and amount of stool produced. ● Lab Test Considerations: May cause slightly elevated serum and urine glucose Ophth (Adults and Children): 1– 2 drops in eye(s) prior to examination or 1– 2 drops in eye(s) every 3– 4 hr for lubricant effect. ● Laxative: Assess patient for abdominal distention, presence of bowel sounds, and normal pattern of bowel function. concentrations. ROUTE ONSET PEAK DURATION Potential Nursing Diagnoses Rect (laxative effect) unknown 15–30 min unknown Constipation (Indications) Deficient knowledge, related to medication regimen (Patient/Family Teaching) Ophth (reduced corneal swelling) unknown unknown 3–4 hr Implementation ● Rect: Glycerin suppository or enema usually causes evacuation of the colon in Contraindications/Precautions Contraindicated in: Hypersensitivity. Use Cautiously in: Severe dehydration; Geriatric patients (increased risk of dehydration). 15– 30 min. Patient/Family Teaching ● Instruct patient to take glycerin as directed. Do not take more than the amount prescribed. ⫽ Canadian drug name. ⫽ Genetic Implication. CAPITALS indicate life-threatening, underlines indicate most frequent. Strikethrough ⫽ Discontinued. PDF Page #1 Name /bks_53161_deglins_md_disk/glycerin 02/14/2014 02:13PM Plate # 0-Composite pg 2 # 2 2 ● Laxative: Advise patient that laxatives should be used only for short-term therapy. PDF Page #2 Long-term therapy may cause electrolyte imbalance and dependence. ● Caution patients not to use laxatives when abdominal pain, nausea, vomiting, or fever is present. Evaluation/Desired Outcomes ● Soft, formed bowel movement. ● Decrease in corneal edema. Why was this drug prescribed for your patient? 䉷 2015 F.A. Davis Company
