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Introduction Aquatic ecosystem is the most diverse ecosystem in the world that includes rivers, streams, ponds, lakes, oceans, bays, swamps, marshes and their associated organisms. Aquatic habitat provides food, water, shelter, and space essential for the survival of aquatic animals and plants. First life originated in the water and first organisms were also aquatic, where the water was first external as well as internal milieu for organisms. Thus water is the most vital factor for the existence of all living organisms. Very less amount of water content in the river (0.00015 %) and lakes (0.01 %) that comprises the most valuable fresh water resources. (Bhalla, 2006) The quantity and quality of water is of vital importance, since it is directly linked with human welfare. A reliable and safe water supply is the basic requirement for development and stability. In a view of the depletion of water resources and deterioration of the quality of water available to the living organisms due to various reasons including industrialisation, urbanisation, conservation and management of water bodies has primary importance. To conserve the valuable water bodies from further deterioration there is need for a regular monitoring of the aquatic ecosystem. Comprehensive biomonitoring process involves both physico-chemical and biological approaches and gives exact status of the aquatic ecosystem. Biomonitoring of water bodies at regular intervals also help to understand the composition of biota and its dynamics and implication of water quality on tropic structure and vice-versa. In the overall process of evaluation physical, chemical and biological nature of water in relation to the natural quality, human effects and intended uses, particularly the uses which may affect human health and health of aquatic ecosystem itself is termed as water quality assessment (Chapman, 1996). Hydrobiology, the science of life and life processes in water is a special section of limnology, the science of inland waters (Schwoerble, 1970). Hydrobiology includes include the biological, physical and chemical aspects of the river, lake and pond water. The goal of the current study is elucidation of basic environmental functions of an ecosystem. The Godavari River is 2nd largest river in southern India. It rises in Sahyadri hills at an altitude of about 10067″m near Trimbakeshwar in the Nashik district of Maharashtra State and is important for water quality management. Different physico-chemical parameters of water and their monthly variations studied in the four selected sampling stations of Godavari River. Physical parameters define those characteristics of water that respond to the sense of site, temperature, Conductivity, Total dissolved solids, Suspended solids and chemical parameters are related to the solvent capabilities of water like pH, Total Alkalinity, Total hardness, chlorides, dissolve oxygen, biological oxygen demand, chemical oxygen demand, sodium, phosphates, ammonia, NO2+NO3 Microbial Parameter Total coliforms and Faecal coliforms. Total eighteen parameters were studied with their correlation with themselves as well as biotic components like zooplanktons (Rotifers, Cladocerans, Copepodes) at four stations A, B, C, D (Gangapur dam, Near Someshwar temple, Ramkund upstream and Ramkund downstream) respectively. Fort night survey was carried out and three seasons were considered (winter, summer and monsoon) as per climate of central India. The physico-chemical parameters showed significant seasonal variations. These temporal fluctuations were either by various physico-chemical parameters which were positively or negatively correlated to each other and on the other hand with the biotic components too, indicating the cumulative influence of the physic- chemical parameters to govern the biotic components of the river. Further, among the biotic parameters zooplankton density and diversity are studied. Zooplankton plays an important role in maintaining the equilibrium between living organisms and abiotic factor. Zooplanktons were also influenced by the changes in abiotic parameters as well as biotic parameters or the combination of both (Christou, 1998; Roff et. al., 1998; Escribano and Hidalgo, 2000; Beyst et al., 2001). Although zooplanktons exist under a wide range of environmental conditions, yet many species are limited due to temperature, dissolve oxygen and other physico-chemical parameters. Zooplankton constitutes an important link in food chain as grazers (primary and secondary consumers) and serves directly or indirectly as food for fishes. Therefore any adverse effect to them is reflected with decline in the fish population. Thus monitoring them as biological indicators acts as a forewarning for the fisheries particularly when the population affects the food chain (Mahajan, 1981). Thus the use of zooplankton for ecological bio-monitoring helps in analysis of water quality trends, development of cause-effect relationships between water quality and environmental data and judgement of adequacy of water quality for various uses. Thus the present study deals with the hydro-biological studies of one important aquatic ecosystem of “Godavari River”. Objectives:-Objectives of present study were as follows, To assess the quality of Godavari river water using various physico-chemical and biological parameters. To evaluate the load of pollutants entering into the Godavari River, using key parameters such as a DO, BOD and COD etc. To study the zooplankton population diversity. To study the total zooplankton population density. Study Area: Godavari River:Nashik has a glorious history of 4500 years of rich culture, religion and wisdom. Nashik city has grown on both sides of river Godavari, the area under control of the Nashik Municipal Corporation measures about 259.12 sq.km. Nashik is situated on the eastern slopes of North – South Sahyadri ranges at 565 meters above mean sea level. It is located between 90035″ and 20052″ North latitude and 73016″ and 74056″ East longitude. The Godavari River selected for the present investigation originates in the Nashik district at Trimbakeshwar in Maharashtra State. It rises in the Sahyadri range near Trimbakeshwar and drains in Nashik and Niphad Tahasils. After passing through Trimbakeshwar town, Godavari turns to east cutting deep and rock bed. During its course, many small and seasonal streams, meet Godavari, the important is Kadawa, Kashyapi, and Nasardi, the Girna, the Mosam and Darana (Census of India 1991), all these river are east flowing origination in Sahyadri. Materials and Methods:To study the hydrobiology of river, four sampling stations A, B, C and D as Gangapur dam, Near Balaji temple, Ramkund upstream and Ramkund downstream respectively of Godavari River were selected. Abiotic and biotic parameters were studied by fortnight surveys carried out for two years from May 2009 to April 2011 Physico-chemical parameters: Among physical parameters, Temperature, Conductivity, Total dissolved solids, suspended solids whereas for chemical parameters, pH, DO, Chlorides, Nitrates and Nitrites, Phosphates, BOD, COD, Ammonia, Sulphate Total alkalinity, Total hardness were estimated using standard methods of analysis as per APHA (2005). Zooplanktons: To collect zooplankton thirty liters of water was filtered using a zooplankton net No.25 and sample was preserved in 4% formalin and brought to the laboratory for detailed studies. Qualitative and Quantitative studies of zooplanktons were carried out with the help of keys given by Edmonson (1963), Sarode and Kamat (1984), Battish (1992) and APHA. Results:Physical parameters and Chemical parameters:- Temperature is one of the most important abiotic factors which regulate various activities. During the study period, water temperature showed fluctuation in accordance to climatic change. Maximum temperature was recorded in summer and minimum in winter. Total solids includes total dissolved solids and suspended solids which showed seasonal variations. Chemical parameters include pH, Total hardness, Alkalinity, Chlorides. Phosphates, Nitrites and Nitrates, BOD, COD, DO, Total dissolve solids, suspended solids and Electrical conductivity. These parameters showed seasonal variations. Biotic parameters:- The biotic parameters include zooplanktons. In the present study the abundance and species richness of zooplankton groups in decreasing order were Rotifer > Copepod > Cladocera species. Richness of total zooplanktons were fluctuating by seasonal variation and correlation with parameters. Zooplankton data was studied by using different biodiversity indices. The results obtained are duly supported by the statistical calculations. The data of the result as obtained is presented in the form of tables and graphs, and photographs. Correlation studies are presented with the calculated r values. After summary and conclusions, the references are quoted at the end of the thesis.