Download Nuclear Medicine: Musculoskeletal system

Musculoskeletal system
Definition
The skeletal system provides support and shape. The major organs are bone, cartilage, tendons and ligaments.
 Bone provides support and protection, stores minerals, and forms blood cells in marrow.
 Cartilage is a flexible, connective tissue that is made up of mostly water.
 Tendons are tough bands of fibrous connective tissue that usually connect muscle to bone.
 Ligaments are a sheet or band of tough, fibrous tissue connecting bones or cartilages at a joint or supporting an organ.
Role of molecular imaging
Molecular imaging radiopharmaceuticals such as technetium-99m medronate, technetium-99m oxidronate or florine-18 sodium fluoride
can be useful in the skeletal system by imaging the bones to help delineate areas of altered osteogenesis.
Radiopharmaceutical
Manufacturer
Trade names
Approved indications in adults
(pediatric use as noted)
Technetium-99m
pyrophosphate
Covidien
Pharmalucence
Technescan™
PYP™
As a bone imaging agent to delineate areas of
altered osteogenesis
Technetium-99m oxidronate
Covidien
Technescan™
HDP
As a bone imaging agent to delineate areas of
altered osteogenesis (adult and pediatric use)
Technetium-99m medronate
Bracco Diagnostics
DRAXIMAGE
DRAXIMAGE
GE Healthcare
Pharmalucence
MDP-Bracco
MDP
MDP Multidose
Fluorine-18 sodium fluoride
Various
TM
As a bone imaging agent to delineate areas of
altered osteogenesis
PET bone imaging agent to delineate areas of
altered osteogenesis
MSDS and package insert information
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