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Pollution and Human Health Environmental Effects on Health 2 ways that pollution causes illness: • Direct poisoning – ie. lead brain damage, learning problems, asbestos lung cancer • Indirect poisoning – infectious diseases spread through a polluted environment – ie: cholera & river blindness caused by organisms in polluted water The WHO…. No, not the band…. the World Health Organization • Has defined poor health worldwide is measured by the estimated # of days of healthy life lost to death & disease • Has determined that in general… – People in developed countries suffer fewer health impacts due to environmental causes than people in developing countries do – Main factor…the enormous role of infectious diseases (ie- TB and cholera) that are common in crowded areas w/ poor sanitation. Poor Health by World Region (Notice least developed area are affected more) Toxicology - the study of the harmful effects of substances on organisms • Toxicity is determined by: – how much of the pollutant is in the environment – How much gets into the body • Dose – amount of a harmful chemical to which a person is exposed (the amount/ concentration of the toxin that damages the body) • Response – how the body responds to the dose of chemical. – depends on… – The dose, # of times a person is exposed, person’s size, how well the body breaks down the chemical Pollutants . . . Their Sources and Affects on Humans Pollution from Natural Sources Naturally occurring pollutants usually become hazardous to health when they are above their normal levels – Example --> Radon Gas • Particulates – particles in the air that are small enough to breathe into the lungs – Examples --> dust and soot from dust storms, volcanic eruption, and wildfires • Can cause irritation in the lungs by clogging the small air sacs which can lead to chronic bronchitis & emphysema • Heavy Metals – includes arsenic, cadmium, lead, & mercury which naturally occur in rocks & soil – Most cause nerve damage when ingested beyond their threshold dose Pollution from Human Activities • ~10% of commercial chemicals have been tested for their toxicity, however ~1,000 new chemicals are produced every year • Recent Improvements – US regulations have helped reduce our exposure to pollutants – Most vehicles & factories now have pollutioncontrol devices – But…new health risks are being discovered frequently Examples of Pollution from Human Activities: • Burning Fuels – in cars, homes, power plants, & factories adds huge amounts of pollutants into the air • including CO and many kinds of particulates • Which contribute to premature deaths each year – In some areas…it may be possible to predict an area’s death rate based on the amount of pollution Examples of Pollution from Human Activities: • Pesticides - chemicals designed to kill unwanted organisms such as insects, fungi, or weeds. – Beneficial = allow more food to be grown – Dangerous = to humans in large enough doses – Organophosphates have recently replaced more persistent pesticides (DDT) • Benefit = breakdown in nature quickly • Danger = very toxic to those exposed typically in application – Persistent pesticides (like DDT) are still used in developing countries • Very bad for children! Examples of Pollution from Human Activities: • Industrial Chemicals – Toxic chemicals are found in new buildings b/c of the new materials (ie- carpet, furniture, cleaners) – In old buildings, lead-based paint, PCBs – All of which do not breakdown in the environment & can cause learning/development delays Examples of Pollution from Human Activities: • Waste Disposal – Wastewater from cities can carry oil & toxic chemicals into our waterways – Waste incinerators emit toxic products into the air – Mines release toxic contaminants into streams & rivers – Improvements have been made in the last 50 years! • But… – Landfills leak – Sewage treatment plants release raw sewage after heavy rains – Waste disposal laws are not always enforced Terms Often Associated With Contaminated Sites • Superfund Sites = sites with the worst hazardous waste contamination nationwide – Twin Cities Army Ammunition Plant (TCAAP) Superfund Site, in Minneapolis/St. Paul metropolitan area (7 contaminated groundwater sites, 1 contaminated sediment site, 2 landfills, 2 firing ranges, 2 unexploded munitions/ordnance sites, 2 surface disposal areas, 1 disposal pit/dry well site, 3 chemical disposal sites, 1 small arms range, and 4 burn areas). • RCRA Sites = When accidents or other activities at hazardous waste facilities lead to a release of hazardous materials, the RCRA Corrective Action program is one program that may be used to accomplish the necessary cleanup – Motiva Terminal, Fairfax, VA • Brownfield – property complicated by the presence or potential presence of a hazardous substance, pollutant, or contaminant. It is estimated that there are more than 450,000 brownfields in the U.S. http://www.pca.state.mn.us/index.php/waste/waste-and-cleanup/cleanup-programs-andtopics/topics/remediation-sites/twin-cities-army-ammunition-plant-tcaap-superfund-site.html?menuid=&redirect=1 Biological Hazards to Health The Environment’s Role in Disease The Environment’s Role in Disease • Infectious diseases are caused by pathogens – organisms that cause disease – Spread person to person through the air • ie: whooping cough & tuberculosis (TB) – Spread by drinking water that contains the pathogen – Transmitted by a secondary host (ie: mosquito) • Host – organism in which a pathogen lives all/part of its life Waterborne Disease • 3/4ths of infectious diseases are transmitted through water • In developing countries water is used for: – Washing – Drinking – Sewage disposal • Polluted water is a good breeding ground for pathogens – Pathogens breed in water and transfer diseases directly to humans through water – Vectors – organisms that transmit diseases to people, may also transfer diseases to humans Waterborne Disease • Cholera (and Dysentery) • Deadliest waterborne diseases come from drinking water polluted by human feces • Cause the body to lose water by diarrhea and vomiting – much deadlier to children because of less water in their bodies Waterborne Disease – Malaria – once the world’s leading cause of death • Caused by parasitic protists and is transmitted by a bite from a female mosquito. • No effective vaccine exists but preventative measure are used to control mosquitoes. Environmental Change and Disease Humans altering the environment • Humans alter the environment in ways that make it more suitable for pathogens to live and reproduce. – i.e.- soil (that is polluted with chemicals & pathogens) erodes which causes pollutants to blow & wash away causing contamination thousands of miles away Environmental Change and Disease Humans altering the environment – Antibiotic Resistance • Overuse of antibiotics in both humans and organisms used for food has led to a large resistance to antibiotics. – ie – Salmonella, E. coli & TB – large amount of resistance causes thousands to get sick every year Environmental Change and Disease Humans altering the environment – Malaria on the March • Global warming may increase the area where malaria occurs. • At one time mainly occurred in rice paddies and marshes – Paddies and marshes were drained & treated with pesticides – Mosquitoes have since developed a resistance to most pesticides – Newer methods for control include growth regulators and female sterilization Environmental Change and Disease Humans altering the environment – Emerging Viruses – previously unknown viruses (less than 100 years old) • Examples: – – – – AIDS – caused by HIV Hanta virus – a type of hemorrhagic fever Ebola virus – a type of hemorrhagic fever West Nile virus – many times found in birds • Problems with emerging viruses: – Not many effective drugs – Main defense is vaccination very specific & viruses evolve rapidly » New strain = New vaccine Environmental Change and Disease Humans altering the environment – Cross-Species Transfers • Diseases that have crossed from one species to another after living for a long time in one species with little damage. – Examples: » HIV » West Nile • Some believe that the way that we are altering the environment & destroying habitats ensure that diseases like these will become more common in the future. Environmental Change and Disease Humans altering the environment – Examples of Cross-Species Transfers • Argentina – Hanta Virus – Herbicides killed native grasses which allowed new plants to move in, which brought with it rodents that carry strains of hemorrhagic fever • Hong Kong – Hong Kong Influenza – Influenza spreads from animals to humans and back again easily (particularly birds) – Many times can be found in poultry markets in crowded areas