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Transcript
Biomolecules
Carbohydrates
• Carbon,
hydrogen,
oxygen, and
nitrogen make
up the bulk of
living matter,
but there are
other
elements
necessary for
life
• Organic molecules are characterized by having
a central “backbone” made of atoms of carbon
linked to each other like a “chain” of carbon
atoms. Other atoms can link to the carbon
backbone
• There are 4 main types of biomolecules:
Carbohydrates
Lipids
Proteins
Nucleic Acids.
How do we build large
molecules?
• Most of the large molecules in living things
are macromolecules called polymers
• Polymers are long chains of smaller
molecular units called monomers
• A huge number of different polymers can be
made from a small number of monomers
• Cells link monomers to form polymers by
dehydration synthesis
1
2
3
Short polymer
Unlinked monomer
Removal of
water molecule
2
1
3
Longer polymer
4
• Polymers are broken down to monomers by
the reverse process, hydrolysis
1
2
3
4
Addition of
water molecule
1
2
3
Coating of
capture strand
Figure 3.3B
CARBOHYDRATES
• Carbohydrates are a class of molecules
• They include sugars, starches and fiber.
• Composed of the elements C, H and O
• Major source of energy from our diet
• Produced by photosynthesis in plants
Types of Carbohydrates
• Monosaccharides
Single monomer
• Disaccharides
Contain 2 monosaccharide units
• Polysaccharides
Contain many monosaccharide units
Monosaccharides are the
simplest carbohydrates.
• Monosaccharides are single-unit sugars
• These molecules typically have a formula
that is a multiple of CH2O (examples)
• Monosaccharides are the fuels for cellular
work.
• Many monosaccharides form rings, as shown
here for glucose
• Many monosaccharides form rings, as shown
here for glucose
Abbreviated
structure
Figure 3.4C
Examples of 6 C Monosaccharides
H
C O
H C OH
HO C H
CH2OH
C O
HO C H
H
O
C
H C OH
HO C H
H C OH
H C OH
H C OH
H C OH
H C OH
CH2OH
CH2OH
CH2OH
D-Glucose
D-Fructose
HO C H
Galactose
Honey
• Honey is a sweet, thick sugary
solution made by bees. The
composition of honey consists of
varying proportions of fructose,
glucose, water, oil and special
enzymes produced by bees. It
also has gluconic acid hydrogen
peroxide that make honey
inhospitable to bacteria, mold,
and fungi, organisms we call
microbes.
Hunter of bees, Arana, Spain
7000 BCE
Energy
Glucose + Glucose
H2O
Maltose
Enzyme
Enzyme
Energy
H2O
Energy
H2O
Disaccharides Store Energy and Serve As Building Blocks
Glucose + Fructose
Energy
Enzyme
Enzyme
Sucrose
H2O
Energy
Glucose + Galactose
Energy
H2O
Enzyme
Enzyme
Lactose
H2O
What is sucrose? Table Sugar!
Primary Plant Sources of table sugar
Sugar Cane – Saccharum officinarum
Sugar Beet – eta vulgaris
Sorghum – Sorghum bicolor
Palm – Phoenix dactylifera
Maple – Acer saccharum
The average USA sugar
consumption per capita per year
is 60 lbs.
Oh Boy! All I
need now
is some sugar!
Sugar Cane
Saccharum officinarum – member
of Poaceae (Grass family)
Native to: Polynesia
Sugar Cane Fields, Queensland Australia, Spring 2006
Sugar Beet, the sugar of
temperate climates
Beta vulgaris – Chenopodiaceae
(Goosefoot Family)
Sugar Beet Fields. Cornwall England, Summer 2006
North American Sweetener
Acer saccharum – Sugar Maple
Maple Syrup
Sap is collected in early spring
Sap is boiled in “sugar house”
40 gallons sap Æ 1 gallon syrup
ƒ What is lactose?
Lactose is the dissacharide
sugar found in milk!
ƒ What is lactose
intolerance?
Are you lactose intolerant?
Do you know somebody
who is?
ƒ Lactose intolerance is a
condition that those who
are afflicted cannot digest
milk.
• This is the normal hydrolysis reaction
Energy
Glucose + Galactose
Energy
H2O
Enzyme
Enzyme
Lactose
H2O
• A lactose intolerant person does not have
the enzyme that breaks down the lactose,
therefore lactose is indigetable and it
causes indigestion!
How sweet is sweet?
• Various types of molecules, including non-sugars,
taste sweet because they bind to “sweet” receptors
on the tongue.
Polysaccharides
• Polysaccharides are carbohydrates
composed of many monosaccharides.
• There are two types of
polysaccharides
ÖStorage Polysaccharides: They
store energy
ÖStructural Polysaccharides: These
are use for building cell structures.
Polysaccharides are long chains of
sugar units
• These large molecules are polymers of
hundreds or thousands of monosaccharides
linked by dehydration synthesis
Energy
1. Glucose + Glucose
H2O
Enzyme
Energy
Maltose
n(H2O)
2. Maltose + n(Glucose)
Polysaccharide
Enzyme
n = many
• Starch and glycogen are storage
polysaccharides that store sugar for later
use
• Cellulose
is a structural polysaccharide in
plant cell walls
Starch granules in
potato tuber cells
Glycogen granules
in muscle tissue
Cellulose fibrils in
a plant cell wall
Cellulose
molecules
Glucose
monomer
STARCH
GLYCOGEN
CELLULOSE
• Starch is a storage polysaccharide composed
entirely of glucose monomers.
• One unbranched form of starch, amylose, forms a
helix.
• Branched forms, like amylopectin, are more
complex.
• Animals that feed on plants, especially parts rich
in starch, can also access this starch to support
their own metabolism.
Fig. 5.6a
• Animals also store glucose in a
polysaccharide called glycogen.
• Glycogen is highly branched, like
amylopectin.
• Humans and other vertebrates store
glycogen in the liver and muscles but only
have about a one day supply.
Insert Fig. 5.6b - glycogen
•Other polysaccharides, structural polysaccharides serve
as building materials for the cell or whole organism. This is
the case of cellulose commonly known as fiber. Cellulose
is the main component of the cell wall of plants.
wood is mostly cellulose
plant cell with cell wall
close-up of cell wall
individual
cellulose
molecules
bundle of
cellulose
molecules
cellulose fiber
• The enzymes in our body cannot hydrolyze the
bonds in cellulose.
• Cellulose in our food passes through the digestive
tract and is eliminated in feces as “insoluble fiber”.
• As it travels through the digestive tract, it abrades
the intestinal walls and stimulates the secretion of
mucus.
• Some microbes can digest cellulose to its glucose
monomers through the use of cellulase enzymes.
• Many eukaryotic herbivores, like cows and termites,
have symbiotic relationships with cellulolytic
microbes, allowing them access to this rich source
of energy.
• Another important structural polysaccharide
is chitin, used in the exoskeletons of
arthropods (including insects, spiders, and
crustaceans).
• Chitin also forms
the structural
support for the
cell walls of
many fungi.