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Transcript
Coronary Stents
BY: COURTNEY MEDEIROS
BME 281
11/30/11
Coronary Artery Disease
 Leading cause of death in United States for men and
women
 Caused by buildup of plaque in arteries
 Heart tissue is deprived of nutrients
 Risk factors:
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Age
Gender
Genes
Symptoms and Tests for Coronary Artery Disease
 Symptoms:
 Vary in strength
 Chest pain
 Fatigue
 Shortness of breath
 Weakness
 Tests:
 ECG
 Exercise Stress Test
 Nuclear Stress Test
 CT Scan
 Coronary Angiograph
Coronary Angioplasty with Stents
 Common treatment for Coronary Artery Disease
 Process:
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Blockage is defined through coronary angiography
Incision is made
Cardiac catheter is guided to the heart through an artery of the groin
or arm
Guide wire is manipulated to
lie across the blockage
Heparin is a given to thin the
blood and prevent clotting
Stent balloon catheter is transported
along the guide wire and is positioned
over the blockage
Saline is pumped into the balloon to inflate it
Balloon is inflated for 30 to 60 seconds to expand the stent
Stents
 Expandable
 Mesh-like tube
 Invented to overcome short comings of regular
coronary angioplasty
 Stays in artery permanently
Kinds of Stents
 Uncoated Stents
 Bare metal
 Drug-coated Stents
 Coated with Sirolimus
 Controlled release of medicine into tissue
 Drug limits overgrowth of natural tissue
 Anti-rejection-type medicine (10% vs 26%)
Pros & Cons
 Pros
 Less invasive than open heart
surgery
 Short procedure
 Failure rate 1%
 Cons
 Not a cure
 Aggravates kidney function
 Stents can’t be used in every
surgery
 Can be rejected by body
Questions?
Sources
 http://www.heartsite.com/html/stent.html#superio
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r
http://en.wikipedia.org/wiki/Coronary_stent
http://www.mayoclinic.com/health/angioplasty/MY
00352/DSECTION=what%2Dyou%2Dcan%2Dexpec
t
http://www.cypherstent.com/cypherstent/pages/index.aspx
http://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0
004449/