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Schizophrenia and Thought Disorders DSM-IV Criteria DSM-IV Diagnostic Criteria for Schizophrenia: A. Characteristic symptoms: Two (or more) of the following, each present for a significant portion of time during a 1-month period (or less if successfully treated): Delusions Hallucinations Disorganized speech (e.g., frequent derailment or incoherence) Grossly disorganized or catatonic behavior Negative symptoms, i.e., affective flattening, alogia, or avolition Note: Only one Criterion A symptom is required if delusions are bizarre or hallucinations consist of a voice keeping up a running commentary on the person's behavior or thoughts, or two or more voices conversing with each other. B. Social/occupational dysfunction: For a significant portion of the time since the onset of the disturbance, one or more major areas of functioning such as work, interpersonal relations, or self-care are markedly below the level achieved prior to the onset (or when the onset is in childhood or adolescence, failure to achieve expected level of interpersonal, academic, or occupational achievement). C. Duration: Continuous signs of the disturbance persist for at least 6 months. This 6-month period must include at least 1 month of symptoms (or less if successfully treated) that meet Criterion A (i.e., active-phase symptoms) and may include periods of prodromal or residual symptoms. During these prodromal or residual periods, the signs of the disturbance may be manifested by only negative symptoms or two or more symptoms listed in Criterion A present in an attenuated form (e.g., odd beliefs, unusual perceptual experiences). D. Schizoaffective and Mood Disorder exclusion: Schizoaffective Disorder and Mood Disorder With Psychotic Features have been ruled out because either (1) no Major Depressive Episode, Manic Episode, or Mixed Episode have occurred concurrently with the active-phase symptoms; or (2) if mood episodes have occurred during active-phase symptoms, their total duration has been brief relative to the duration of the active and residual periods. E. Substance/general medical condition exclusion: The disturbance is not due to the direct physiological effects of a substance (e.g., a drug of abuse, a medication) or a general medical condition. F. Relationship to a Pervasive Developmental Disorder: If there is a history of Autistic Disorder or another Pervasive Developmental Disorder, the additional diagnosis of Schizophrenia is made only if prominent delusions or hallucinations are also present for at least a month (or less if successfully treated). Subtypes of Schizophrenia: Paranoid Type: A type of Schizophrenia in which the following criteria are met: Preoccupation with one or more delusions or frequent auditory hallucinations. None of the following is prominent: disorganized speech, disorganized or catatonic behavior, or flat or inappropriate affect. Catatonic Type: A type of Schizophrenia in which the clinical picture is dominated by at least two of the following: Motoric immobility as evidenced by catalepsy (including waxy flexibility) or stupor Excessive motor activity (that is apparently purposeless and not influenced by external stimuli) Extreme negativism (an apparently motiveless resistance to all instructions or maintenance of a rigid posture against attempts to be moved) or mutism Peculiarities of voluntary movement as evidenced by posturing (voluntary assumption of inappropriate or bizarre postures), Stereotyped movements, prominent mannerisms, or prominent grimacing Echolalia or echopraxia Disorganized Type: A type of Schizophrenia in which the following criteria are met: All of the following are prominent: Disorganized speech Disorganized behavior Flat or inappropriate affect Undifferentiated Type: A type of Schizophrenia in which symptoms that meet Criterion A are present, but the criteria are not met for the Paranoid, Disorganized, or Catatonic Type. Residual Type: A type of Schizophrenia in which the following criteria are met: Absence of prominent delusions Hallucinations Disorganized speech Grossly disorganized or catatonic behavior. There is continuing evidence of the disturbance, as indicated by the presence of negative symptoms or two or more symptoms listed in Criterion A for Schizophrenia, present in an attenuated form (e.g., odd beliefs, unusual perceptual experiences). Definition Schizophrenia is a category of mental disorders that cause a person to hallucinate, lose a grasp on reality, create false beliefs and lose motivation, among other abnormal behavior. Treatment for schizophrenia is long-term and focuses on managing symptoms with proper medication and training people on how to deal with individual daily stresses. Statistics According to the National Institute for Mental Health, 1 in 100 people is likely to develop schizophrenia The peak onset period is between ages 15 and 30 Approximately 1 percent of the general public develops the disorder after the age of 15 Schizophrenia is equally as likely to appear in men as it is in women. Symptoms in men occur usually in the late teens to early 20s, while women often see symptoms in their 20s to early 30s. Causes Little is known about a specific cause for schizophrenia; however, there are common theories: Malfunction in the brain's neurotransmitters, which are chemicals that communicate with nerve endings to produce behavior Nerve cells processing the neurotransmitters dopamine and serotonin have often been shown to exhibit abnormalities in people with schizophrenia Symptoms Symptoms are generally severe enough to interfere with social interaction, employment and basic self-care and are categorized as either positive (hallucinations, delusions) or negative (slow thinking, speech, movement). Delusions Hallucinations Disorganized speech Grossly disorganized or catatonic behavior (extremely agitated or zombielike) Negative symptoms (abnormal symptoms of dullness, or flatness feeling)\ The symptoms cause social and occupational dysfunction Course of Illness The first episode of schizophrenia usually occurs in teenage years, although some cases may occur in the late thirties or forties. Onset prior to puberty is rare, though cases as early as five years old have been reported. Schizophrenia itself is not fatal, although a small percentage of people may be prone to violent outbursts or self harm. The disorder is manageable, but expected to be lifelong. Diagnosis The diagnosis of schizophrenia is made on the basis of symptoms, course of illness, and, when available, family history. The diagnostic criteria for schizophrenia is described in the Diagnostic and Statistical Manual for Mental Disorders, fourth edition (DSM-IV). **see DSM-IV criteria section above Treatment Medication: Antipsychotics help relieve the positive symptoms of schizophrenia by helping to correct an imbalance in the chemicals that enable brain cells to communicate with each other. Chlorpromazine (Thorazine) Fluphenazine (Prolixin) Haloperidol (Haldol) Thiothixene (Navane) Trifluoperazine (Stelazine) Perphenazine (Trilafon) Thioridazine (Mellaril) Risperidone (Risperdal) Clozapine (Clozaril) Olanzapine (Zyprexa) Psychosocial Rehabilitation: People with schizophrenia who attend structured psychosocial rehabilitation programs and continue with their medical treatment manage their illness best. Supportive psychotherapy: Individual or family counseling may be a helpful adjunct to reduce risk for relapse. Community programs: Beneficial in providing support, social skills training, and vocational rehabilitation. Hospitalization: People who experience acute symptoms of schizophrenia may require intensive treatment including hospitalization. Hospitalization is necessary to treat severe delusions or hallucinations, serious suicidal thoughts, an inability to care for oneself, or severe problems with drugs or alcohol. Accommodations Maintaining Stamina during the Workday (e.g. – restlessness, increased or decreased energy): Flexible scheduling Allow longer or more frequent breaks Provide additional time to learn new responsibilities Provide self-paced work load Provide backup coverage for when the employee needs to take breaks Allow for time off for counseling Allow for use of supportive employment and job coaches Allow employee to work from home during part of the day or week Part time work schedules Maintaining Concentration (e.g. – restlessness, distractibility, racing thoughts): Reduce distractions in the work area Provide space enclosures or private office Allow for use of white noise or environmental sound machines Increase natural lighting or provide full spectrum lighting Allow the employee to work form home and provide necessary equipment Plan for uninterrupted work time Allow for frequent breaks Divide large assignments into smaller tasks and goals Restructure job to include only essential functions Difficulty Staying Organized and Meeting Deadlines (e.g.- difficulty making decisions, impaired cognitions): Make daily TO-DO lists and check items off as they are completed Use several calendars to mark meetings and deadlines Remind employee of important deadlines Use electronic organizers Divide large assignments into smaller tasks and goals Working Effectively with Supervisors (e.g. – blunted affect, suspicious behavior, avoidance, responding negatively to criticism): Provide positive praise and reinforcement Provide written job instructions Develop written work agreements including the agreed upon accommodations, clear expectations of responsibilities and the consequences of not meeting performance standards Allow for open communication to managers and supervisors Establish written long term and short term goals Develop strategies to deal with problems before they arise Develop a procedure to evaluate the effectiveness of the accommodation Memory Deficits: Use voice activated recorder to record verbal instructions Provide written information Provide checklists Prompt employee with verbal cues (reminders) Post written or pictorial instructions on frequently-used machines Performing Calculations: (e.g. – impaired cognition) Allow use of calculator Large-display calculator Talking calculator Use counter or ticker Provide talking tape measure Use liquid level indicators Mark the measuring cup with a "fill to here" line Disorganization: Minimize clutter Color-code items or resources Provide 1-2-3 chart Divide large tasks into multiple smaller tasks Label items or resources Use symbols instead of words Use print labels instead of hand-written labels Time Management/Performing or Completing Tasks: (e.g. - limitations in adaptive skills, slow reaction time) Provide verbal prompts (reminders) Provide written or symbolic reminders Use alarm watch or beeper Use jig for assembly to increase productivity Arrange materials in order of use Use task list with numbers or symbols Avoid isolated workstations Provide space for job coach Provide additional training or retraining as needed Difficulty Handling Stress and Emotions (e.g. – poor judgment, hallucinations, delusions): Provide praise and positive reinforcement Refer to counseling and employee assistance programs Allow telephone calls during work hours to doctors and others for needed support Provide sensitivity training to coworkers and supervisors Allow the presence of a support animal Reinforce peer supports Attendance Issues (e.g. – loss of interest): Provide flexible leave for health problems Provide a self-paced work load and flexible hours Allow employee to work from home Provide part-time work schedule Allow the employee to make up time missed Additional Information on Thought Disorders Formal thought disorders are not unique to individuals displaying schizophrenia symptoms. Loose associations and preservation may also be manifested in individuals during episodes of mania. Also, even when people function normally, they may organize statements loosely or on occasion use words that others fail to understand, especially when they're tired or ill. Incidences of formal thought disorders however, are much more common and severe. Research has found that some disorganized speech or thinking may appear long before an entire pattern of schizophrenia unfolds and/or is diagnosed. Recommended Readings Job Accommodations Network (JAN) The Job Accommodation Network (JAN) is a free consulting service that provides information about job accommodations, the Americans with Disabilities Act (ADA), and the employability of people with disabilities. http://www.jan.wvu.edu/links/ Psychiatric Disabilities: Reasonable Accommodations: This on-line resource provides information about reasonable accommodations for people with psychiatric disabilities, specifically in order to aid employers and educators. Reasonable accommodations are those adjustments within a work or school site that allow an otherwise qualified employee or student with a disability to perform the tasks required. http://www.bu.edu/cpr/reasaccom/ Mental Health Matters Mental Health Matters, was founded to supply information and resources to mental health consumers, professionals, students and supporters. While the percentage of people facing a diagnosable Mental Disorder in any given year is substantial, the acceptance of these problems can be hard to come by. Essentially, Mental Health Issues are hidden illnesses. The main purpose is to provide a structured source of information about mental health issues. To this end, Mental Health Matters will offer detailed technical briefs on disorders, symptoms, treatment modes, and in time, a "comparison engine" that allows users to compare different aspects of disorders. With this information, we hope to educate consumers and guide them towards intelligent decisions in their pursuit of Mental Health. http://www.mental-health-matters.com/disorders/index.php Research Article Mueser, K.T., Bellack, A.S., Douglas, M.S., & Morrison, R.L. (1991). Prevalence and stability of social skills deficits in schizophrenia. Schizophrenia Research, 5, 167-176.