Survey
* Your assessment is very important for improving the workof artificial intelligence, which forms the content of this project
* Your assessment is very important for improving the workof artificial intelligence, which forms the content of this project
Peptide synthesis wikipedia , lookup
Amino acid synthesis wikipedia , lookup
Genetic code wikipedia , lookup
Nucleic acid analogue wikipedia , lookup
Biosynthesis wikipedia , lookup
Citric acid cycle wikipedia , lookup
Fatty acid synthesis wikipedia , lookup
Biochemistry wikipedia , lookup
15-Hydroxyeicosatetraenoic acid wikipedia , lookup
Butyric acid wikipedia , lookup
Chemistry Sensors: Loggers: pH Any EASYSENSE Logging time: 1 minute Teacher’s notes 06 Comparing the effectiveness of antacids Read A popular cure for acid indigestion is to take an antacid, these stop acid indigestion by neutralising the acid in the stomach with a mild alkaline substance. Some of the more modern antacids work by stopping the stomach from producing the acid in the first place, often you can work out the difference by reading the description on the box. Those brands offering “immediate relief” are more likely to be based on the alkali, the brands offering “up to 12 hours relief” will be more likely to stop the acid being produced. There are many brands of antacids available. In this investigation different brands of antacids are tested to see which one, if any, is the most effective and possibly what the best value to buy is. The investigation is useful in that it provides an everyday application of some simple chemistry, even if the students are not familiar with indigestion they will have seen the advertisements for such cures and be familiar with the idea. Apparatus 1. An EASYSENSE logger. 2. A Smart Q pH sensor. 3. Large beaker and wash bottle of distilled water (to rinse pH electrode after each use). 4. Stirrer – a simple glass rod or a magnetic stirrer. 5. 4 beakers of different types of antacid labelled A, B, C and D. E.g. 20 cm3 of antacid solution made by dissolving 5 g of antacid in 50 cm3 of distilled water. As an alternative use powdered antacid or a crushed tablet to produce a much more dramatic reaction. Note: Solutions should all be the same temperature. 6. 4 x 100 ml beakers containing the same volume (20 cm3) and concentration of acid (0.1 mol dm-3 hydrochloric acid) or cola Set up of the software and logger Use the setup file 06 Antacids. To set the logger and software manually use the details in the table, Recording method Total recording time Display Graph 1 minute Overlay mode L2 Chemistry T06 - 1(V2) The intersample time is not particularly important, but don’t be tempted to go too short, the frothing and fizzing will create jumps in pH which can give a jagged recording. Using a longer intersample time effectively smoothes the data. The setup file uses the default intersample time for the 1 minute recording time. Notes The frothing and fizzing should be mentioned, it can catch some individuals by surprise. Students may not immediately recognize that the froth has potentially harmful effects, their experience will have suggested to them that foams and froths are fun. The extension suggests using the work to calculate the cost of an antacid to cure indigestion. This is a good exercise in using fact to find value for money and to move the science out of the test tube and into life. If you intend to use commercial anti indigestion products do read the labels carefully, many of the modern products are chemical inhibitors of nerve pathways in the stomach and stop the stomach from producing acid rather than neutralising it. A simple test is to look for a mention of one tablet lasts 12 hours. Usually acid neutralisers have short action period due to digestive transit times. L2 Chemistry T06 - 2(V2)