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Integumentary system – part 2 Key terms Dermis: • Also called “corium” • Directly below the epidermis • Contains blood and lymph vessels • Contains accessory organs – hair, sweat glands, sebaceous glands • Contains connective tissue cells and fibers Dermis: • Fibers present are collagen and elastic • Collagen – tough, resistant, also flexible – Found in bones, ligaments, cartilage, tendon – Loose in infants, harder as age increases – Support and protect the blood and nerve networks – Connective tissue diseases: Scleroderma, Lupus Dermis • Dermis (corium) –can be divided into 2 sublayers: • papillary sublayer and reticular sublayer Papillary sublayer - highly vascular structures that provide oxygen and nutrients to the epidermis that surrounds them. - Contain pain receptors and tactile sensory receptors. Reticular layer • Reticular Sublayer – • dense form of connective tissue • contains blood vessels, sweat glands, sebaceous glands, and the sensory receptors for cold, heat, and pressure. • Unlike the epidermis, the dermis contains blood vessels and nerves • Contains both sebaceous (oil-producing) glands and sudoriferous (sweat-producing) glands Dermis layer Interesting fact • Did you know that skin is water proof, it does not allow water to go in and more importantly it does not allow water to go out! Subcutaneous layer: • Another connective tissue layer • Mainly the formation and storage of fat • Lipocytes – fat cells – numerous in this layer • Areas in the body where fat is stored, varies from person to person • Important for protection of deeper tissues, heat insulator, energy storage Hair: • Single hair fiber: tightly fused meshwork of keratin-filled cells • Growth of hair cells similar to skin cells • Hair follicle: shaft that holds the hair fibers • Meaning of follicle – “small sac” • Melanocytes are present in the root of hair follicle – give color to the hair • 5 million hair on the body, 100,000 on the head • Grow half an inch per month Nail: • Hard keratin plates, composed of hardened cells of the stratum corneum. • Cover the back of the last bone (phalanx) of each toe and finger. • Cells are cemented together. • Can grow indefinitely if not cut. • 1 mm per week, toenails are slower. Nail: • Lunula: semilunar white region at the base of the nail, air mixed with the keratin and cells rich in nuclei give the lunula its whitish color. • Cuticle: narrow band of epidermis at the base and sides of the nail • Paronychia: infection in the soft tissue surrounding the nail border Nail: • Grooves in nails occur in high fever and serious illness • Flattening of nails – called spoon nail – happens in iron deficiency anemia • Loosening of the nail and separation from the nail bed – Onycholysis – happens with infection of nail. Sebaceous gland: • Found all over the body, in the dermis, except on the palm and sole • Secrete sebum, an oily substance – lubricates the skin and minimizes water loss • Closely associated with hair follicles • Influenced by sex hormones – can cause hypertrophy at puberty and atrophy in old age • Blackheads and acne: due to overproduction of sebum Sebaceous gland Sweat gland: • Tiny, coiled glands • Found almost everywhere on the body • About 2 million • Most numerous in the hand • Coiled in the dermis, straightens out as it reaches the surface • Opens into the “pore” of the skin • Also known as sudoriferous (latin - sudor – sweat + ferre – bear) glands Sweat gland: • Sweat – almost pure water, other material like salt is only 1% • Colorless, odorless • Odor – from action of bacteria on accumulated sweat • Sweat cools the body Sweat gland: • Secretion is controlled by sympathetic nervous system • Signal comes from hypothalamus (part of the brain) • Specialized sweat glands – “apocrine glands” • Concentrated around the reproductive organs and armpits, grow especially after puberty • Mammary gland is a modified sweat gland Interesting fact: • If you laid out all your skin on a flat surface, it would have an area of about 2 square meters. Cutis • Cutis - skin (latin) - cutis is also the origin of the adjective cutaneous, which refers to the skin • Ex. Cutis Ansernia, also known as goose bumps, a temporary local change in the skin when it becomes rougher due to erection of little muscles, as from cold, fear, or excitement. Cyan/o • Cyan/o – blue • Ex. Cyanosis is a bluish discolouration of the skin and mucous membranes due to excessive concentration of reduced hemoglobin in the blood. -Cyte • -Cyte – cell • Ex. Melanocyte are special cells in the skin and the eye that synthesize melanin pigments. Derm/o; Dermat/o • Derm/o; dermat/o – skin • Ex. Dermatology is the study of the skin and its diseases. Dermatologist is a physician who specializes in dermatology and who diagnoses and treats skin abnormalities. Kerat/o • Kerat/o – horn-like tissue • Ex. Keratin is a protein that is the primary constituent of hair, nails, and skin. Leuk/o • Leuk/o – white • Ex. Leukocyte is a white blood cell. Leukoderma: is the absence of pigment, partial or total, in the skin. Partial or total loss of skin pigmentation, often occurring in patches. Also called vitiligo. Onych/o • Onych/o – having to do with the nails; fingernails, toenails • Ex. Onychia Lateralis is inflammation involving the folds of tissue surrounding the nail. Pil/o • Pil/o – hair • Ex. Pilocystic denotes a dermoid cyst containing hair. • Dermoid cyst: A benign tumor resulting from abnormal embryonic development, occurring in the skin or ovary. Sub• Sub- - below • Ex. Subcutaneous Layer is under the skin. Dermatomycosis • Dermatomycosis – fungal infection of the skin • dermat/o – “skin” • myc/o – “fungus” • -osis – “abnormal condition” Dermatopathy • Dermatopathy – any disease of the skin • derm/a/t/o – “skin” • -pathy – “disease” Dermatoplasty • Dermatoplasty – plastic surgery performed on the skin • derm/a/t/o – “skin” • -plasty – “surgical repair” Epidermatitis • Epidermatitis – inflammation of the epidermis • epi – “upon” • -dermis – “skin” • -itis – “inflammation” Melanoma • Melanoma – tumor of the melanocytes; black colored skin tumor • melan/o – “black” • -oma – “tumor” Onychectomy • Onychectomy – surgical removal of a nail • onych/o – “nail” • -ectomy – “incision” Onychomalacia • Onychomalacia – softening of the nails • onych/o – “nail” • malacia – “softening” Onychomycosis • Onychomycosis – fungal infection of a nail • onych/o – “nail” • mycosis – “fungal infection” Onychopathy • Onychopathy – any disease of the nails • onych/o – “nail” • -pathy – “disease” Onychoplasty • Onychoplasty – surgical repair of a nail • onych/o – “nail” • plasty – “repair” Onychotomy • Onychotomy – incision into a nail • onych/o – “nail” • -tomy – “incision” Paronychia • • • • Paronychia – infection around a nail para – “adjacent” onych/o – “nail” -ia – “condition” Cuticle • Cuticle – common word used as a synonym for the eponychium • from the latin word cutis meaning “skin” Eponychium • Eponychium – thin, transparent layer of skin located at the nail root Lunula • Lunula – white, crescent-shaped area of a nail • from the latin word luna meaning “moon” Vellus • Vellus – fine hair that covers much of the body • from the latin word meaning “fleece” • The End