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Talks on BACTERIA and BIOFILMS Talk 1. Strategies for Prevention and Treatment of Biofilms Professor Rikke Louise Meyer, Interdisciplinary Nanoscience Centre, Aarhus University Denmark Time: Monday, May 29th at 1400 “ Bacteria are tiny living things that like to attach to surfaces. Most bacteria are harmless, but if the harmful bacteria get into the human body where they do not belong, they can cause an infection. Infections make the human body very sick. Most infections with bacteria can be cured by antibiotics, but not infections caused by biofilms! Biofilms are communities of bacteria living together and covered in protective sticky goo, and most antibiotics do not work against them. Here, we explain how biofilms protect bacteria from antibiotics, and what we can do to fight with these long-term infections.1 1. Okshevsky M and Louise Meyer R (2016) Big Bad Biofilms: How Communities of Bacteria Cause Long-Term Infections. Front Young Minds. 4:14. doi: 10.3389/frym.2016.00014 ” Talk 2. The world of Mycobacteria Expectations and Surprises Professor Leif A. Kirsebom at Department of Cell and Molecular Biology, Structural and Molecular Biology,Uppsala RNA Research Centre – URRC. Director at Uppsala Biomedical Centre, BMCintendenturen Time: Monday, May 29th at 1500 The Mycobacterium genus lists 174 species and the number is increasing. The genus includes nonpathogenic environmental bacteria, opportunistic and highly successful pathogens such as M. tuberculosis that causes tuberculosis. Mycobacteria are divided into rapidly and slow growing mycobacteria. They are acid fast, robust and can inhabit various environmental reservoirs and can be present in food and appear to have a growth advantage in water containing disinfecting agents. Mycobacteria can be invasive, can cause latent infections and they form aggregates and biofilms, and show changes in their cell shape during growth and some can form spores. We have undertaken a systematic global approach to understand the biology of this important group of bacteria with special emphasis on its adaptive abilities under stress and changes in cell morphology. Genome data, comparative genomic analysis, gene expression under different growth conditions for selected mycobacterial species will be presented and discussed Location: Swedish Medical Nanoscience Center Seminar Room, Department of Neuroscience, Scheeles väg 1, Solna Campus