Download Table 2. Dosing of Selected Enteral Contrast Agents

Table 2. Dosing of Selected Enteral Contrast Agents According to Product Labeling
Drug
Dosage
How
Concentration
Comments
Supplied
Oral
Rectal
Barium
E-Z-Disk 3,27
Swallow one 700 mg
Not labeled
Tablet
700 mg
Tablet is ½ inch in
tablet with 1-2
diameter and will
swallows of water
disintegrate within 30
minutes.
E-Z-HD 28
Adults
Not labeled
Suspension
98% w/w
Use immediately after
65 mL to 135 mL
reconstitution.
Digibar 190 29
Adults
Not labeled
Powder for
190% w/v
Use within 8 hours of
120 mL
suspension
reconstitution.
Maxibar 30
Adults
Not labeled
Suspension
210% w/v
Use undiluted for
50 mL to 120 mL
double-contrast
examination of the
esophagus, stomach
and duodenum.
Not labeled
Suspension
60% w/v
Use undiluted for single
Liquid E-ZAdults
contrast fill stomach
Paque 31
Single contrast fill
with small bowel followstomach with small
through, routine small
bowel follow through:
bowel, and follow
150 mL to 340 mL
through small bowel
after double contrast
Routine small bowel:
upper GI study.
340 mL to 750 mL
Ultra-R 32
E-Z-Paque 33
Follow through small
bowel after double
contrast upper GI
study: 340 mL to 750
mL
Adults
Upper GI: 150 mL to
340 mL
Small bowel: 340 mL
to 750 mL
Adults
Upper GI: 150 mL to
340 mL
Small bowel: 340 mL
to 750 mL
Not labeled
Powder for
suspension
95% w/w
After reconstitution, use
within 48 hours and
refrigerate.
Used when rapid transit
through bowel is
required.
Not labeled
Powder for
suspension
96% w/w
After reconstitution, use
within 48 hours and
refrigerate.
Table 2 continued. Dosing of Selected Enteral Contrast Agents According to Product Labeling
Drug
Dosage
How
Concentration
Comments
Supplied
Oral
Rectal
Barium
Adults
Suspension
105% w/v
Volume and
Liquid Polibar
Adults
100% w/v
concentration used
Plus
Double-contrast
Single
depends on
esophagus study: 60
contrast
gastrointestinal location
Liquid Polibar mL to 300 mL
studies: 1000
34,35
being imaged,
undiluted suspension. mL to 2500
technique and
mL of diluted
equipment.
Single or double
suspension.
contrast stomach
Dilute in 1:5
series: 150 mL to 340 ratio.
mL diluted or
undiluted, depending
Double
on study.
contrast colon
studies: 500
Small bowel series:
mL to 1500
340 mL to 750 mL
mL of
undiluted
suspension.
Adults
Readi-CAT 2 36 Adults
Suspension
2.1% w/v
Shake well prior to use.
30 minute barium
300 mL to 400
Readi-CAT 2 is
administration
mL rectally.
available in the
protocol for
following flavors: apple,
abdomen: Give 300
banana, vanilla, berry,
mL 30 minutes before
and mochaccino.
CT scan and 150 mL
immediately prior to
scan.
90 minute barium
administration
protocol for
abdomen: Give 450
mL 90 minutes before
CT scan, give
another 300 mL 30
minutes before scan,
and 150 mL
immediately prior to
scan.
Table 2 continued. Dosing of Selected Enteral Contrast Agents According to Product Labeling
Drug
Dosage
How
Concentration
Comments
Supplied
Oral
Rectal
Barium
Not labeled
Powder for
2% w/w
After reconstitution, use
E-Z-CAT Dry 37 Adults
suspension
within 48 hours and
30 minute barium
refrigerate.
administration
protocol for
abdomen: Give 300
mL 30 minutes before
CT scan and 150 mL
immediately prior to
scan.
90 minute barium
administration
protocol for
abdomen: Give 450
mL 90 minutes before
CT scan, given
another 300 mL 30
minutes before scan,
and 150 mL
immediately prior to
scan.
VoLumen® 38
Adults
900 to 1350 mL orally
given 20 to 30
minutes prior to
procedure.
Water soluble iodinated contrast media
Diatrizoate
Adults
meglumine and 30 to 90 mL
diatrizoate
sodium
Pediatric Patients
(Gastrografin®)9 Infant to children < 5
years: 30 mL
Children 5 to 10
years: 60 mL
For CT use:
Adults
240 mL of diluted
solution 15 to 30
minutes prior to
procedure. To make
a dilute solution mix
25 mL Gastrografin
with one liter tap
water.
Not labeled
Suspension
0.1% w/v
Dose can be increased
to 1800 mL for
enhanced marking, in
patients with delayed
transit time and for
obese patients.
Adults
240 mL in
1000 mL tap
water.
Solution
37%
organically
bound iodine
For pediatric patients
weighing 10 kg or less
and debilitated children,
dilute 1 part
Gastrografin in 3 parts
water.
Pediatric
patients
< 5 years of
age: 1:5
dilution in tap
water
>5 years of
age: 90 mL in
500 mL tap
water.
Table 2 continued. Dosing of Selected Enteral Contrast Agents According to Product Labeling
Drug
Dosage
How
Concentration
Comments
Supplied
Oral
Rectal
Nonionic iodine based contrast agents
Can be given
Solution
30.2% to
Give the oral dose 20 to
Iohexol
Adults
75.5%
40 minutes prior to
(Omnipaque®)10 Undiluted Omnipaque rectally with
larger volumes
intravenous dose.
350: 50 to 100 mL
used. The
product
For pediatric patients,
Diluted Omnipaque
labeling does
the total iodine dose
Concentration:
should not exceed 5
not provide
6 to 9 mg Iodine/mL:
gram iodine for patients
specific
500 mL to 1000 mL
under 3 years of age
dosages.
Note: smaller
and 10 grams iodine for
volumes are needed
patients 3 to 18 years
as concentration is
of age.
increased.
Pediatric Patients
Undiluted Omnipaque
< 3 months of age: 5
to 30 mL
3 months to 3 years:
up to 60 mL
4 to 10 years: up to
80 mL
> 10 years: up to 100
mL
Diluted Omnipaque
Concentration:
9 to 21 mg Iodine/mL:
180 mL to 750 mL
Note: smaller
volumes are needed
as concentration is
increased.
Iohexol can be mixed
with water, juice, milk or
carbonated beverage. 10,39
Omnipaque 350 is
labeled for pass thru
examination in adults.
Omnipaque 300 and
Omnipaque 240 are
labeled for pass thru
examination in children