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Immune System C) Body’s defense against germs 1) Define immunity- your body’s resistance to germs and the harmful substances they produce 2) How do these five things fight off germs from entering your body? FIRST LINE OF DEFENSE -Tears – Wash germs from your eyes -Skin – if the skin is unbroken, you are protected. Germs enter when you are cut, burned or scraped -Mucous Membrane – in your nose, mouth and throat. Secrete mucus that traps germs -Saliva – washes germs from your mouth and cleans your teeth. -Gastric Juices – produced in your stomach, they destroy germs MAIN LINE OF DEFENSE 3) What role does a phagocyte play in your immune system? What is otherwise known as? Engulf and destroy germs once they do enter your body (phagocytosis) 1) What does interferon do? A substance that is released by the body when a germ is present and stops the virus from reproducing and infecting other cells 2) When you are ill, you body raises it’s core temperature. Why? It is killing germs that cannot survive higher body temperatures SPECIFIC IMMUNITY – if the germs do survive the general immune reaction (phagocytosis), your lymphatic system takes over D) Lymphatic System – a secondary circulatory system of vessels and nodes that carry lymph. It helps maintain the balance of fluids in the body that help fight germs. 1) 2) Lymph nodes – small lumps of tissue located throughout the system that filters to keep germs from invading body tissues. When a germ infects the area, your lymph nodes become swollen because they are in action. Lymphocytes – Special white blood cells in lymph a. B-Cells – fight germs b. T-Cells attach germs and stimulate B-Cells to work HOW THE IMMUNE SYSTEM RESPONDS TO VIRUSES Virus enters body – makes it past the first and main line of defense T –Cells identify the virus and multiply and activate B-cells B-Cells multiply and produce antibodies (proteins that attach to germs and prevent them from harming the body) or stuns them Special T-Cells destroy the virus Memory B-cells and T-cells store the virus or germ to memory in case of re-entry E) Vaccine – Dead or weakened germs that are injected into the body to cause the immune system to produce antibodies against it.