Download What if you could select some of the most effective

WELLNESS WORKS
By Design
What if you could select some of the most effective and
innovative nutritional formulations in the market today
and place them in YOUR vitamin line? Well, that’s exactly what we
did with our new Wellness Works By Design products. Our team of PCCA member
nutritional consultants selected existing products in the marketplace and designed
others to create a more innovative product line. I invite you to flip through these
pages and become acquainted with our newest additions to the Wellness Works
line, Wellness Works By Design.
John Preckshot, RPh, CCN
Director, Wellness Works Nutrition
[email protected]
800-331-2498
levels.
5-HTP capsules contain 75 mg of natural L-5hydroxytryptophan (5-HTP) extracted from seeds of the
Griffonia plant, together with 7.5 mg of Vitamin B-6 (as
pyridoxine-5-phosphate).
Serotonin, an important brain neurotransmitter, is key in
the regulation of appetite, mood, and melatonin
production. The presence of serotonin in the brain is
associated with a balanced emotional state. This is
achieved in part by decreasing the activity of certain
excitatory hormones, including dopamine and
noradrenaline. Serotonin also acts as a satiety signal in the
brain, thereby naturally regulating food intake.
Additionally, as a precursor of melatonin, serotonin is
involved in regulating sleep patterns.
Serotonin is unable to cross the blood-brain barrier and is
therefore synthesized in the brain. Tryptophan, an
essential amino acid, is a precursor for the synthesis of
serotonin. Tryptophan crosses the blood-brain barrier and
is converted to L-5-hydroxytryptophan, which in turn is
converted into serotonin. Unfortunately, tryptophan faces
many obstacles during its journey into brain tissue. First,
dietary intake directly affects body levels of tryptophan, as
the body cannot endogenously produce it. High protein
diets often provide greater amounts of tryptophan, yet
higher carbohydrate diets appear to enhance tryptophan
uptake into the brain. Secondly, tryptophan must compete
with other amino acids for entry into the brain. Finally,
tryptophan may be taken up by other tissues for protein or
niacin synthesis, and thus is not exclusively for use by the
brain.
As a metabolic intermediate in the conversion of
tryptophan into serotonin, 5-HTP can also serve as a
precursor of serotonin. 5-HTP offers a number of
advantages over tryptophan. 5-HTP is derived naturally
from the seeds of the Griffonia plant, unlike tryptophan
which is produced synthetically or through bacterial
fermentation. 5-HTP crosses into the brain more readily
than tryptophan as it is able to cross the blood-brain
barrier without competition for uptake. 5-HTP is
significantly more effective than tryptophan; one 50 mg
capsule of 5-HTP is roughly equivalent to 500 mg of
tryptophan. Finally, research studies have shown 5-HTP
to be safe at levels as high as 900 mg. As a result, 5-HTP
is a safe and effective means of increasing brain serotonin
These statements have not been evaluated by the
Food and Drug Administration. This product is not
intended to diagnose, treat, cure, or prevent any disease.
5-HTP capsules may be a useful nutritional supplement
for individuals wishing to obtain the benefits of this welldocumented plant extract to increase their levels of brain
serotonin.
L-5-hydroxytryptophan ........................................ 75 mg
Pyridoxal 5-Phosphate (P-5-P) ............................ 7.5 mg
Proprietary Blend (L-tyrosine, L-Glutamine) ....... 50 mg
As a dietary supplement, adults take one (1) capsule daily
with meals, or as directed by a healthcare professional.
Vitamin B6 is necessary for the conversion of 5-HTP to
serotonin. Thus, an adequate intake of vitamin B6 is
necessary to derive optimal benefits of 5-HTP.
No adverse effects have been reported.
Store in a cool, dry place, away from direct light. Keep
out of reach of children.
Chan S, Gerson B, Subramaniam S. The role of copper, molybdenum,
selenium, and zinc in nutrition and health. Clin Lab Med 1998;18:673-85.
Colodny, L, Hoffman, RL. Inositol--clinical applications for exogenous
use. Altern Med Rev 1998;3:432-47. Durlach J, Bac P, Durlach V, et al.
Magnesium status and ageing: an update. Magnes Res 1998;11:25-42.
Guyton, JR, Capuzzi, DM. Treatment of hyperlipidemia with combined
niacin-statin regimens. Am J Cardiol 1998;82:82U-84U; discussion 8586U.
Halperin ML, Kamel KS. Potassium. Lancet 1998;352:135-40.
Jansonius, JN. Structure, evolution and action of vitamin B6-dependent
enzymes. Curr Opin Struct Biol 1998;8:759-69.
Lakshmi, AV. Riboflavin metabolism--relevance to human nutrition.
Indian J Med Res 1998;108:182-90.
Prasad AS. Zinc and immunity. Mol Cell Biochem 1998;188:63-9.
Reid IR. The roles of calcium and vitamin D in the prevention of
osteoporosis. Endocrinol Metab Clin North Am 1998;27:389-98.
Manufactured for:
PCCA
9901 S. Wilcrest Dr.
Houston, TX 77099
281.933.6948
Active Essentials For Men is a targeted nutritional
formula conveniently dose-packaged, providing
comprehensive nutritional support. The formula includes
Albion® chelated minerals; activated B vitamins;
Quatrefolic®, Oxygen Radical Absorbance Capacity
(ORAC) botanicals; and fresh, pure, third-party assayed
fish oils. Calcium is in the form of di-calcium malate and
microcrystalline hydroxyapatite concentrate (MCHC).
The average diet can be lacking in complete nutrition due
to modern food-production techniques, poor food choices,
and nutrient-depleting preparation methods.[1-3] Combine
these with the toll of lifestyle stress and oxidizing
chemicals—found in foods and the environment—and it
becomes essential to ensure comprehensive foundation
nutrition for the body. To achieve this, each cellophanewrapped package of Active Essentials For Men contains
the following Company Name formulas:
Multivitamin Formula w/o Iron: This high-quality,
hypoallergenic, proprietary multivitamin/mineral blend is
provided in vegetable capsules and not only features
activated vitamin co-factors and patented Albion®
chelated mineral complexes, but it also provides folate as
a blend of folic acid and 5-MTHF. The form of 5-MTHF
is Quatrefolic®, which is proven to have greater stability,
solubility, and bioavailability over the calcium salt forms
of 5-MTHF. The balanced nutrient profile in Multivitamin
Formula w/o Iron supports vitamin/mineral synergistic
activity; antioxidant protection with vitamins C and E,
selenium, and carotenoids; and Phase 1 detoxification.
Omega-3 Formula: Each enteric-coated softgel contains
1.2 g of fish oil, delivering 360 mg eicosapentaenoic acid
(EPA) and 240 mg docosahexaenoic acid (DHA). A
rigorous, proprietary, temperature-controlled/vacuum
technology is used for purification and manufacturing.
Stringent verification processes reduce any potential
health risks which may otherwise result from the oil’s
exposure to rancid fats, toxins, bacteria, molds, yeasts, or
very high levels of fat-soluble vitamins, such as vitamin
A. Wellness Works is proud to guarantee the quality,
potency, purity, stability, and disintegration time of
Omega Oils. In addition to complying with a host of
federal and state regulations, our supplier also agrees to
adhere to voluntary guidelines for manufacturing and to a
code of ethics as members of the Council for Responsible
Nutrition. Research suggests that consumption of EPA
and DHA omega-3 fatty acids may support cardiovascular
health.[5] Studies have also shown that fish oils may
support a healthy response to inflammation, promote
optimal joint function[6], and support overall brain and
nervous system function.[7]
Active Essentials For Men may be a useful dietary
supplement for those who wish to improve their nutrient
intake and receive antioxidant support.
Vitamin A ........................................................ 3750 I.U.
(75% [2,812 IU] as mixed carotenoids and 25% [938 IU] as
cis-retinol palmitate)
Vitamin C ........................................................... 125 mg
Antioxidant Formula: This innovative blend of
oxidation-fighting botanicals contains RosemarinX™,
derived from rosemary, and Berr-X™, derived from a
variety of berries. The technique known as ORAC
measures antioxidant capacity, and units of an ORAC
value are expressed as micromoles Trolox Equivalents per
gram of a substance. Consuming an average of five to nine
servings per day of a variety of fruits and vegetables
yields 6000 Trolox Equivalents. This same amount is
supplied by just two capsules (1000 mg) of Oraxinol.[8]
(as potassium ascorbate, zinc ascorbate, calcium ascorbate,
and sodium ascorbate)
Calcium................................................................. 50 mg
(as DimaCal® Di-Calcium Malate and calcium ascorbate)
Vitamin D3 (as cholecalciferol) ......................... 100 I.U.
Vitamin E ........................................................... 100 I.U.
(as d-alpha tocopheryl succinate and mixed tocopherols)
Vitamin B1 (as thiamine mononitrate) .................. 10 mg
Vitamin B2 (as riboflavin 5’ phosphate) ............... 10 mg
Vitamin B3 (as niacinamide and niacin) ............... 32 mg
Vitamin B6 (as pyridoxal 5’ phosphate) ............... 10 mg
Folate .................................................................200 mcg
(100 mcg as folic acid & 100 mcg as 5-methyltetrahydrofolate)
Vitamin B12 (as methylcobalamin) ...................250 mcg
BiotinPantothenic Acid ......................................500 mcg
(as d-calcium pantothenate)
Iodine (as potassium iodide) ............................... 100 mg
Magnesium (as Di-Magnesium Malate) ...............50 mcg
Zinc (TRAACS® Zinc Glycinate Chelate) ........... 50 mg
Selenium (as Selenium Glycinate Complex) ........ 6.5 mg
Copper .................................................................50 mcg
(TRAACS® Copper Glycinate Chelate)
Manganese .........................................................500 mcg
(TRAACS® Manganese Glycinate Chelate)
Chromium ..........................................................250 mcg
(TRAACS® Chromium Nicotinate Glycinate Chelate)
Molybdenum ......................................................250 mcg
(TRAACS® Molybdenum Glycinate Chelate)
Potassium .............................................................25 mcg
(as potassium glycinate and potassium ascorbate)
1. National Health and Nutrition Examination Survey. Centers for
Disease Control and Prevention. http://www.cdc.gov/nchs/nhanes.htm.
Accessed February 22, 2011.
2. What we eat in America. USDA Agricultural Research Service
http://www.ars.usda.gov/main/site_main.htm?modecode=12-35-50-00.
Accessed February 22, 2011.
3. Worthington V. Nutritional quality of organic versus conventional
fruits, vegetables, and grains. J Altern Complement Med. 2001
Apr;7(2):161-73. [PMID: 11327522]
4. Albion TRAACS® big news in mineral amino acid chelate history.
Albion Human Nutrition. http://www.albionminerals.com/humannutrition/quality/traacs-ft-ir-analysis. Accessed March 13, 2011.
5. FDA announces qualified health claims for omega-3 fatty acids. U.S.
Food and Drug Administration Department of Health and Human
Services.
http://www.fda.gov/NewsEvents/Newsroom/PressAnnouncements/2004/u
cm108351.htm. Accessed February 27, 2011.
6. Proudman SM, Cleland LG, James MJ. Dietary omega-3 fats for
treatment of inflammatory joint disease: efficacy and utility. Rheum Dis
Clin North Am. 2008 May;34(2):469-79. [PMID: 18638687]
7. Cole GM, Ma QL, Frautschy SA. Dietary fatty acids and the aging
brain. Nutr Rev. 2010 Dec;68(suppl 2):S102-11. [PMID: 21091943]
8. Price JA, Sanny CG, Shevlin D. Application of manual assessment of
oxygen radical absorbent capacity (ORAC) for use in high throughput
assay of “total” antioxidant activity of drugs and natural products. J
Pharmacol Methods. 2006 July-Aug;54(1):56-61. [PMID: 16337142]
Inositol Choline (as choline dihydrogen citrate) ... 50 mg
PABA (para-aminobenzoic acid) .......................... 18 mg
Vanadium .............................................................. 18 mg
(TRAACS® Vanadium Nicotinate Glycinate Chelate)
EPA (eicosapentaenoic acid) ............................... 6.5 mg
DHA (docosahexaenoic acid) ............................375 mcg
Other Ingredients for Multivitamin Formula w/o Iron:
HPMC (capsule), microcrystalline cellulose, stearic acid,
magnesium stearate, and silica.
Other Ingredients for Antioxidant Formula: HPMC
(capsule), stearic acid, and magnesium stearate.
Other ingredients for Omega-3 Formula: Gelatin,
vegetable glycerin, food glaze, ethylcellulose, purified
water, enteric coating, and mixed natural tocopherols.
Contains: Fish (anchovy, mackerel, sardine).
As a dietary supplement, adults take 1 packet twice daily,
or as directed by a healthcare professional.
No adverse effects have been reported.
Store in a cool, dry place, away from direct light. Keep
out of reach of children.
These statements have not been evaluated by the
Food and Drug Administration. This product is not
intended to diagnose, treat, cure, or prevent any disease.
Manufactured for:
PCCA
9901 S. Wilcrest Dr.
Houston, TX 77099
281.933.6948
AdreBoost-G contains key nutrients to support healthy
adrenal function including: a bovine glandular blend,
vitamin C, vitamin B6, and pantothenic acid.
Adrenal Blend: The bovine adrenal blend is formulated
to support adrenal, hypothalamus, and pituitary function
by stimulating the release of specific hormones that are
necessary for optimum endocrine health. The adrenal,
hypothalamus, and pituitary glands directly influence each
other to support the stress response, immune system,
mood, emotions, and several other body processes. This is
also known as the hypothalamic-pituitary-adrenal axis
(HPA axis). An HPA axis that is not functioning correctly
can influence mood, stress, and overall health, as hormone
sensitivity decreases. The hormones released by the HPA
axis have been shown to effect physical energy, as cortisol
and ACTH hormones were measured in 30 patients with
chronic exhaustion ailments. Researchers found the
irregular release of cortisol and ACTH hormones had an
effect on health and physical energy.
Rhodiola Rosea: Native to eastern Siberia, Rhodiola
Rosea has been used in Russian traditional medicine for
centuries, as it is known for its adaptogenic activity
(increases the body’s resistance to stress and aids mental
function). Rhodiola’s adaptogenic activity relieves mental
stress. The extract can prevent behavioral and
physiological changes that are often associated with
chronic stress. Furthermore, a single dose of rhodiola has
been shown to stimulate the central nervous system to
balance mood and behavior.29
One study observed the effects of rhodiola extract on 56
healthy physicians that were suffering from fatigue during
night shifts. After two weeks of rhodiola supplementation,
the study found a significant improvement in energy levels
among individuals taking the extract. Researchers
suggested rhodiola can decrease fatigue during stressful
conditions. Another study recruited students to take
rhodiola for 20 days during an examination period.
Results indicated students taking rhodiola had more
physical and mental endurance, when compared to the
placebo group.
Pantothenic Acid: Pantothenic Acid, also known as
vitamin B5, is essential to several metabolic functions,
including the synthesis of steroid hormones,
neurotransmitters, and lipids. Prolonged amounts of stress
can affect the release of stress hormones, such as an
elevation in cortisol levels. To support the adrenals and
normal hormone function, the body needs B-vitamins,
including pantothenic acid. Pantothenic acid can help
alleviate systemic effects of stress.
A six-week study recruited individuals with mood
ailments to take rhodiola extract, finding mood, sleep, and
emotions improved in subjects taking rhodiola extract.
Similarly, rhodiola may alleviate chronic anxiety, as a tenweek study demonstrated it significantly reduced anxiety
among individuals taking the extract. Furthermore, the
stress-relieving effects have been extended to stressrelated cardiovascular ailments, as rhodiola can inhibit
cardiovascular damage.
B vitamins are essential to energy production; specifically,
pantothenic acid is a precursor to important enzymes that
provide optimal cellular energy to help your adrenals
function normally. Furthermore, B vitamins inhibit the
development of oxidative stress that can lead to
accelerated aging. An animal study reviewed the effects of
pantothenic acid on the adrenal glands, finding that
supplementation stimulated adrenal sensitivity to release
corticosterone and progesterone hormones that improve
adrenal function.
Vitamin C: The adrenal gland contains high amounts of
vitamin C, which are depleted at a rapid rate, when the
body is under stress. Vitamin C deficiencies can affect
adrenal gland function, because the adrenal cortex is less
protected against lipid peroxidation and free radical
damage. Researchers examined the antioxidant effects of
vitamin C, beta-carotene, and vitamin E supplementation
among professional basketball players to understand their
role on exercise stress markers. The study measured stress
markers before supplementation, before training, after
training and 24 hours after training. Supplementation
decreased free radical formation and aided stress markers
among athletes participating in strenuous physical
exercise. Another study found that vitamin C
supplementation stimulated circulating cortisol,
adrenaline, and anti-inflammatory properties in ultramarathon runners to support prolonged durations of stress.
Zinc: Zinc is required for energy metabolism, as it is
involved in several metabolic processes. Zinc levels can
decline after strenuous physical stress leading to muscle
fatigue and decreased immunity. Additionally, a zinc
deficiency can increase anxiety-like behavior, as a twoweek zinc deprivation study found the deficiency
increased corticosterone and basal free calcium levels.
your healthcare professional prior to use.
Adrenal Blend – There are no known adverse reactions
with proper supplementation.
Pantothenic Acid – Diarrhea may occur in large doses.
Vitamin C – Stomach upset including nausea, diarrhea,
abdominal cramps may occur in large doses due to
unabsorbed vitamin C passing through the intestines.
Zinc – High doses of zinc can lead to copper deficiency or
cause stomach upset.
Eighty healthy male volunteers were recruited to take a
supplement containing zinc, magnesium, and calcium, or a
placebo, for 28 days to see how supplementation affected
well-being. Subjects taking the vitamin supplement had a
significant reduction in anxiety and perceived stress, when
compared to the placebo group. Furthermore, subjects in
the treatment group experienced more energy and mental
concentration.
Drug Interactions:
Consult a physician before taking NUTRA Adrenal, as the
following key nutrients may interact with certain
medications.
Adrenal Blend – There are no known interactions with
proper supplementation.
Pantothenic Acid – There are no known interactions with
proper supplementation.
Vitamin C – Aluminum-containing antacids, Aspirin
(impairs vitamin C), Chemotherapeutic agents, Estrogen,
or Indinavir.
Zinc – Antibiotics block zinc absorption
AdreBoost-G is formulated to support energy and overall
adrenal health.
Store in a cool, dry place, away from direct light. Keep
out of reach of children.
Vitamin A Acetate .......................................... 5,000 I.U.
Vitamin C (Ascorbic Acid) ................................. 300 mg
Thiamin HCl ........................................................... 3 mg
Riboflavin USP ....................................................... 2 mg
Vitamin B-6 (Pyridoxine HCl) .............................. 50 mg
Pantothenic Acid (d-Calcium Pantothenate) ......... 60 mg
Zinc (Amino Acid Chelate) ................................... 15 mg
Adrenal Concentrate (bovine) ............................. 300 mg
Spleen Concentrate (bovine) ................................. 50 mg
Other Ingredients: Cellulose, Magnesium Stearate
As a dietary supplement, adults take 4 capsules daily with
meals, or as directed by a healthcare professional.
The maximum safe dosages of the nutrients in this formula
have not been determined for children, pregnant or
nursing women, or those with severe liver or kidney
disease. As with all supplement regimens, please consult
Tsigos C, Chrousos GP. Hypothalamic–pituitary–adrenal axis,
neuroendocrine factors and stress. Journal of Psychosomatic Research.
2002; 53:865–871.
Engelmann M, Landgraf R, Wotjak CT. The hypothalamic–
neurohypophysial system regulates the hypothalamic–pituitary–adrenal
axis under stress: An old concept revisited. Frontiers in
Neurodendocrinology. 2004; 25(3-4):132-149.
Machale SM, Cavanagh JT, Bennie J, Carroll S, et al. Diurnal variation of
adrenocortical activity in chronic fatigue syndrome.
Neurophyschobiology. 1998; 38(4):213-217.
Kelly GS. Nutritional and botanical interventions to assist with the
adaptation to stress. Alternative Med Rev. 1999 Aug; 4(4):249-265.
Depeint F, Bruce WR, Shangari N, Mehta R, O’Brien PJ. Mitochondrial
function and toxicity: role of the B vitamin family on mitochondrial
energy metabolism. Chem Biol Interact. 2006; 163(1-2):94-112.
Ames BN, Atamna H, Killilea DW. Mineral and vitamin deficiencies can
accelerate the mitochondrial decay of aging. Mol Aspects Med. 2005;
26(4-5):363-378.
Jaroenporn S, Yamamoto T, Itabashi A, Nakamura K, et al. Effects of
pantothenic acid supplementation on adrenal steroid secretion from male
rats. Biol Pharm Bull. 2008 Jun; 31(6):1205-1208.
Perfumi M, Mattioli L. Adaptogenic and central nervous system effects of
single doses of 3% rosavin and 1% salidroside Rhodiola rosea L. extract
in mice. Phytother Res. 2007; 21(1): 37-43.
Mattioli L, Funari C, Perfumi M. Effects of Rhodiola rosea L. extract on
behavioural and physiological alterations induced by chronic mild stress
in female rats. J Psychopharmacol. 2008 May 30.
Darbinyan V, Kteyan A, Panossian A, Gabrielian E, Wikman G, Wagner
H. Rhodiola rosea in stress induced fatigue-a double blind cross-over
study of a standardized extract SHR-5 with a repeated low-dose regimen
on the mental performance of healthy physicians during night duty.
Phytomedicine. 2000; 7(5): 365-371.
Spasov AA, Wikman GK, Mandrikov VB, et al. A double-blind, placebocontrolled pilot study of the stimulating and adaptogenic effect of
Rhodiola rosea SHR-5 extract on the fatigue of students caused by stress
during an examination period with a repeated low-dose regimen.
Phytomedicine. 2000; 7(2): 85-89.
Darbinyan V, Aslanyan G, Amroyan E, Gabrielyan E, et al. Clinical trial
of Rhodiola rosea L. extract SHR-5 in the treatment of mild to moderate
depression. Nord J Psychiatry. 2007; 61(5): 343-348.
Bystritsky A, Kerwin L, Feusner JD. A pilot study of Rhodiola rosea
(Rhodax) for generalized anxiety disorder (GAD). J Altern Complement
Med. 2008; 14(2): 175-180.
Maslova LV, Kondrat’ev B, Maslov LN, Lishmanov I. The
cardioprotective and antiadrenergic activity of an extract of Rhodiola
rosea in stress. Eksp Klin Farmakol. 1994; 57(6): 61-63.
Patak P. Willenberg HS, Bornstein SR. Vitamin C is an important
cofactor for both adrenal cortex and adrenal medulla. Endocrinol Res.
2004 Nov; 30(4): 871-875.
Hornsby PJ, Crivello JF. The role of lipid peroxidation and biological
antioxidants in the function of the adrenal cortex. Part 2. Mol Cell
Endocrinol. 1983; 30: 123–147.
Sahin K, Sahin N, Yaralioglu S. Effects of vitamin C and vitamin E on
lipid peroxidation, blood serum metabolites, and mineral concentrations
of laying hens reared at high ambient temperature. Biol Trace Elem
Resear. 2002; 85(1): 35-45.
Schroder H, Navarro E, Mora J, Galiano D, Tramullas A. Effects of
alpha-tocopherol, beta-carotene and ascorbic acid on oxidative, hormonal
and enzymatic exercise stress markers in habitual training activity of
professional basketball players. Eur J Nutr. 2001 Aug; 40(4): 178-184.
Peters EM, Anderson R, Nieman DC, Fickl H, Jogessar V. Vitamin C
supplementation attenuates the increases in circulating cortisol, adrenaline
and anti-inflammatory polypeptides following ultramarathon running.
Intern J of Sports Med. 2001; 22(7): 537-543.
Cordova A, Alvarez-Mon M. Behavior of zinc in physical exercise: A
special reference to immunity and fatigue. Neuroscience & Behavioral
Rev. 1995; 19(3): 439-445.
Takeda A, Tamano H, Kan F, Hiromasa I, Oku N. Anxiety-like behavior
of young rats after 2-week zinc deprivation. Behavioural Brain Research.
2007; 177(1): 1-6.
Carroll D, Ring C, Suter M, Willemsen G. The effects of an oral
multivitamin combination with calcium, magnesium, and zinc on
psychological well-being in healthy young male volunteers: a double-blind
placebo-controlled trial. Psychopharmacology. 2000; 150(2): 220-225.
Chapin RE, Ku WW, Kenney MA, McCoy H, Gladen B, Wine RN,
Wilson R, Elwell MR. The effects of dietary boron on bone strength in
rats. Fundam Appl Toxicol 1997;35:205-15.
Eaton-Evans J. Osteoporosis and the role of diet. Br J Biomed Sci
1994;51:358-70.
Meunier PJ, Delmas PD, Eastell R, McClung MR, Papapoulos S, Rizzoli
R, Seeman E, Wasnich RD. Diagnosis and management of osteoporosis
in postmenopausal women: clinical guidelines. International Committee
for Osteoporosis Clinical Guidelines. Clin Ther 1999;21:1025-44.
Nielsen FH. The justification for providing dietary guidance for the
nutritional intake of boron. Biol Trace Elem Res 1998;66:319-30.
O'Brien KO. Combined calcium and vitamin D supplementation reduces
bone loss and fracture incidence in older men and women. Nutr Rev
1998;56:148-50.
Reid IR. The roles of calcium and vitamin D in the prevention of
osteoporosis. Endocrinol Metab Clin North Am 1998;27:389-98.
Sojka JE, Weaver CM. Magnesium supplementation and osteoporosis.
Nutr Rev 1995;53:71-4
These statements have not been evaluated by the
Food and Drug Administration. This product is not
intended to diagnose, treat, cure, or prevent any disease.
Manufactured for:
PCCA
9901 S. Wilcrest Dr.
Houston, TX 77099
281.933.6948
AdreBoost-NG is a combination of nutrients and herbs
that support healthy adrenal function during periods of
physical and emotional stress. The adaptogenic herbs
(Eleuthero, Rhodiola rosea, Ashwagandha) are
standardized to ensure a consistent dose of active
compounds.
The adrenal glands produce hormones that support the
biochemical and physiological mechanisms for dealing
with mental and physical stress, and also secrete
chemicals involved in nutrient metabolism and energy
production. Chronic anxiety, nervous tension and other
types of stress may lead to an excess production of
cortisol, a hormone involved in the stress response.
Excess intake of stimulants such as caffeine and sugar can
exacerbate stress and lead to adrenal “fatigue.” The
constant stimulation of the adrenal glands may eventually
result in an abnormal stress response, low energy and poor
immune function.
The adrenal glands rely on a variety of nutrients to
support their function and produce the hormones that
support the response to physical and emotional stress.
These include tyrosine, which is required for the
production of the adrenal hormones epinephrine
(adrenaline) and norepinephrine (noradrenaline). Vitamin
B6 helps to protect the body from the negative effects of
glucocorticoid hormones such as cortisol. Pantothenic
acid and vitamin C have a supporting role in maintaining
healthy adrenal gland function. The adaptogenic herbs
Rhodiola rosea, ashwagandha, and Eleuthero as well as
the herbs Licorice root, astragalus, gotu kola and
schizandra all provide a synergistic effect by supporting
normal, healthy adrenal function, supporting healthy
cortisol and energy levels, managing the negative effects
of stress on the body and contributing to an overall feeling
of well-being.
AdreBoost-NG may be a useful dietary supplement for
those experiencing physical or emotional long-term stress
or participating in physical activity. AdreBoost-NG
should be taken consistently for maximum benefit.
Vitamin C (as ascorbic acid) ................................ 60 mg
Vitamin B-6 (as pyridoxine HCL) ........................ 25 mg
Pantothenic Acid (d-calcium pantothenate) ........ 100 mg
L-Tyrosine .......................................................... 500 mg
Rhodiola Rosea ................................................... 200 mg
(standardized to 3% [6 mg] rosavins and 1%
[2mg] salidrosides)
Eleuthero............................................................. 100 mg
(Eleutherococcus senticosus) root extract
(standardized to 0.5% [0.5 mg] eleutherosides)
Ashwagandha ...................................................... 150 mg
(Withania somnifera) root extract (standardized
to 1.5% [2.5 mg] withanolides)
Choline (as choline bitartrate)............................... 50 mg
Ginger (Zingiber officinale) .................................. 50 mg
Licorice (Glycyrrhiza glabra) ............................... 40 mg
Astragalus (Astragalus membranaceus) ................ 45 mg
Gotu Kola (Centella asiatica) ................................ 25 mg
Schizandra (Schizandra chinensis)........................ 20 mg
Other Ingredients: Capsules (cellulose, water), magnesium
stearate and silica.
Contains No: sugar, salt, dairy, yeast, soy, wheat, gluten,
corn, preservatives, artificial colors or flavors.
As a dietary supplement, adults take two (2) vegetarian
capsules daily at mealtime, or as directed by a healthcare
professional.
Please consult with a healthcare professional before taking
AdreBoost-NG if you are have high blood pressure or are
currently taking medications to treat depression or anxiety
or taking a class of drugs known as monoamine oxidase
inhibitors (MAOI). Tyrosine may interact with thyroid
medications.
Store in a cool, dry place, away from direct light. Keep
out of reach of children.
De Kloet, E Ron; Holsboers, Florian. “Stress and the Brain From
Adaptation to Disease.” Nature Reviews: Neuroscience. 23.6. (June
2005). 463-475.
Khansari, D. N., A. J. Murgo, et al. (1990). "Effects of Stress on the
Immune System." Immunology Today 44:26 170-175.
Leathwood PD, Pollet P (1982). "Diet-induced mood changes in normal
populations". Journal of Psychiatric Research 17 (2): 147–54.
Lieberman HR, Corkin S, Spring BJ, Wurtman RJ, Growdon JH (1985).
"The effects of dietary neurotransmitter precursors on human behavior".
Am J Clin Nutr. 42 (2): 366–370
Shevtsov VA, Zholus BI, Shervarly VI, et al. (Mar 2003). "A randomized
trial of two different doses of Rhodiola rosea extract versus placebo and
control of capacity for mental work". Phytomedicine 10 (2–3): 95–105.
Wiegant FA, Surinova S, Ytsma E, Langelaar-Makkinje M, Wikman G,
Post JA (Jun 2008). "Plant adaptogens increase lifespan and stress
resistance in C. elegans". Biogerontology 10 (1): 27–42.
Perfumi M, Mattioli L (Jan 2007). "Adaptogenic and central nervous
system effects of single doses of 3% rosavin and 1% salidroside Rhodiola
rosea L. extract in mice". Phytother Res 21 (1): 37–43.
Deyama T, Nishibe S, Nakazawa Y (December 2001). "Constituents and
pharmacological effects of Eucommia and Siberian ginseng". Acta
Pharmacol. Sin. 22 (12): 1057–70
Winston, David & Maimes, Steven. “ADAPTOGENS: Herbs for
Strength, Stamina, and Stress Relief,” Healing Arts Press, 2007. Contains
Russian research on E. senticosus and a monograph on the herb.
Ven Murthy, M. R.; Ranjekar, P. K.; Ramassamy, C.; Deshpande, M.
(2010). "Scientific Basis for the Use of Indian Ayurvedic Medicinal
Plants in the Treatment of Neurodegenerative Disorders: Ashwagandha".
Central Nervous System Agents in Medicinal Chemistry 10 (3): 238–246.
These statements have not been evaluated by the
Food and Drug Administration. This product is not
intended to diagnose, treat, cure, or prevent any disease.
Manufactured for:
PCCA
9901 S. Wilcrest Dr.
Houston, TX 77099
281.933.6948
Betaine Hydrochlorideis a powdered dietary supplement
of hydrochloric acid supplied in two-piece gelatin
capsules.
The breakdown of dietary protein begins in the stomach
where gastric hydrochloric acid assumes an important role
in protein digestion and other processes.
Hydrochloric acid acts as a catalyst in the activation of
pepsin from pepsinogen. Active pepsin is a proteolytic
enzyme which splits large protein molecules into smaller
polypeptides. Additionally, hydrochloric acid acts directly
on dietary proteins by loosening up their macromolecular
structure (denaturing).
No adverse effects have been reported.
Store in a cool, dry place, away from direct light. Keep
out of reach of children.
Pike RL, Brown ML. Nutrition - An Integrated Approach, 3rd edition.
John Wiley & Sons, 1984, pp.211-215.
Steele RD, Harper AE. In:Present Knowledge in Nutrition, 6th edition.
Brown ML ed. International Life Sciences Institute - Nutrition
Foundation, 1990, pp. 67-79.
Wolf M, Ransberger K. Enzyme Therapy. Vantage Press, Inc. New York,
1972.
Gastric hydrochloric acid also helps reduce poorly
available trivalent ferric iron into more soluble and
absorbable divalent ferrous iron.
Another physiological role of gastric hydrochloric acid is
to protect the body from food-borne enteric infections
through its antibacterial properties.
Betaine Hydrochloride capsules may be a useful
nutritional adjunct for individuals who wish to supplement
their diets with hydrochloric acid.
Betaine HCl ........................................................ 648 mg
One capsule just before or during each meal, or as
directed by physician.
These statements have not been evaluated by the
Food and Drug Administration. This product is not
intended to diagnose, treat, cure, or prevent any disease.
Manufactured for:
PCCA
9901 S. Wilcrest Dr.
Houston, TX 77099
281.933.6948
Cinnamon Complex is formulated to support insulin
sensitivity and optimize blood sugar levels. It contains
Cinnulin PF™, a safe, patented 100% aqueous cinnamon
(Cinnamomi cassia) extract[1] plus three other relevant,
high quality, standardized herbs. Alpha Lipoic Acid and a
highly bio-available, Albion®-Chelated form of chromium
are also present.
Cinnulin PF™ contains the bio-active, water-soluble
polyphenol polymers (“Type-A polymers”) that inhibit
PTP-1, preventing inactivation of insulin receptors. They
affect protein phosphorylation-dephosphorylation
reactions regulating glucose metabolism signal
transduction pathways.[2] These Polymers are
antioxidants and increase insulin-dependent glucose
metabolism by roughly 20 times.[3] After 40 days of
consuming either one, three or six grams of cinnamon per
day, subjects had significant reductions in blood glucose
(18-29%) and blood lipids(7-30%).[4]
American Ginseng (Panax quinquefolius) possesses
sulfonylurea-like activity.[5] This herb does not lower
blood sugar unless it contains a significant quantity of
ginsenosides.[6] The American ginseng in Product Name
is a standardized 12% (ginsenosides) extract.
Gymnema Leaf Extract (Gymnema sylvestre) is a watersoluble extract made from the leaves of Gymnema
sylvestre and standardized to 25% gymnemic acid. This
form does not decrease iron absorption as other forms
may.[7] Gymnema can enhance the effects of insulin and
oral hypoglycemic agents by reducing glucose absorption
in the intestine, stimulating pancreatic beta cell growth
and possibly increasing endogenous insulin secretion.
Gymnema may also reduce serum lipids.[8]
Green Tea Polyphenols (Camelia sinesis) protect
erythrocytes from oxidative stress, possibly reducing risk
of late complications of diabetes.[9] In research studies
EGCG enhanced insulin activity,[10] protected the
pancreatic cells by reducing inflammatory cytokines (e.g.
IL-1beta), and reduced IFN-gamma-induced nitric oxide
production. It affected genes that inhibit activation of NFkappaB[11] and reduced the level of messenger RNA for
the hepatic gluconeogenic enzymes.[12]
Alpha Lipoic Acid is a potent antioxidant that acts by
multiple mechanisms, both physiologically and
pharmacologically, in the treatment of diabetic peripheral
neuropathy and hypertension.[13,14] In higher doses,
alpha lipoic acid supports insulin regulation of blood
sugar levels.
Chromium: The Albion® patented process that combines
chromium with glycinate and niacin increases its
bioavailability and improves insulin sensitivity.[15]
Individuals with Type 2 diabetes tend to have lower blood
chromium levels. Chromium enhances the metabolic
action of insulin and may reduce some of the risk factors
for cardiovascular disease, especially in overweight
individuals.
Cinnamon Complex may be a useful dietary supplement
for those who wish to support insulin sensitivity and
optimize blood sugar levels.
Chromium ........................................................... 200 mg
(as TRAACS® chromium nicotinate glycinate chelate)
American Ginseng (Panax quinquefolius) .......... 375 mg
[12% ginsenosides] (whole plant)
Alpha Lipoic Acid .............................................. 200 mg
Green Tea Leaf Extract (Camellia sinensis) ....... 200 mg
[60% catechins; 40% EGCG]
Gymnema Leaf Extract (Gymnema sylvestre)..... 200 mg
[25% gymnemic acids]
CinSulin®‡ (Cinnamomum cassia) .................... 200 mg
[20:1 Aqueous Bark Extract]
Other Ingredients: HPMC (capsule), cellulose, stearic
acid, magnesium stearate, silica.
‡CinSulin® is registered trademark of Tang-An Medical Co., Ltd. U.S.
Patent #6,200,569.
As a dietary supplement, adults take 2 capsules daily, or
as directed by a healthcare professional.
No adverse effects have been reported.
Store in a cool, dry place, away from direct light. Keep
out of reach of children.
1. Anderson RA, et. al. Isolation and characterization of polyphenol typeA polymers from cinnamon with insulin-like biological activity. J Agric
Food Chem. 2004 Jan 14;52(1):65-70. [PMID:14709014]
2. Imparl-Radosevich J, et.al. Regulation of PTP-1 and insulin receptor
kinase by fractions from cinnamon: implications for cinnamon regulation
of insulin signaling. Horm Res. 1998 Sep; 50(3):177-82 [PMID:
9762007]
3. Anderson RA, et al. Isolation and characterization of polyphenol typeA polymers from cinnamon with insulin-like biological activity. J Agric
Food Chem. 2004 Jan 14:52(1):65-70. [PMID: 14709014]
4. Khan A, Safder M, Ali Khan MM, Khattak KN, Anderson RA.
Cinnamon improves glucose and lipids of people with type 2 diabetes.
Diabetes Care. 2003 Dec; 26(12):3215-8. [PMID: 14633804]
5. Rotshtyen Y, Zito SW, Application of modified in vitro screening
procedure for identifying herbals possessing sulfonylurea-like activity. J
Ethnopharmacol. 2004 Aug;93 (2-3):337-44 [PMID: 15234774]
6. Sievenpiper JL, Arnason JT, Leiter LA, Vuksan V. Variable effects of
American Ginseng: a batch of American ginseng (Panax quinquefolius
L.) with a depressed ginesenoside profile does not affect postprandial
glycemia. Eur J Clin Nutr. 2003 Feb; 57 (2):243-8 [PMID: 12571655]
7. Natural Medicines Comprehensive Database.
http://www.naturaldatabase.com. [accessed 1.29.07]
8. Shanmugasundaram, E.R.B., et.al. Use of gynema slyvestre leaf extract
in the control of blood glucose in insulin-dependent diabetes mellitus. J of
Etnopharmacol 1990;30:228-94 [PMID: 2259216]
9. Rizvi SI, Zaid MA, Anis R, Mishra N. Protective role of tea catechins
against oxidation-induced damage of type 2 diabetic erythrocytes. Clin
Exp Pharmacol Physiol. 2005 Jan-Feb; 32 (1-2): 70-5 [PMID: 15730438]
10. Anderson RA, Polansky MM Tea enhances insulin activity. J Agric
Food Chem. 2002 Nov 20; 50(24): 7182-6. [PMID: 12428980]
11. Koyama Y et.al. Effects of green tea on gene expression of hepatic
gluconeogenic enzymes in vivo. Planta Med. 2004 Nov; 70(11):1100-2
[PMID: 15549673]
12. Han MK. Epigallocatechin gallate, a constituent of green tea,
supresses cytokine-induced pancreatic beta-cell damage. Exp Mol Med.
2003 Apr 30;35(2):136-9 [PMID:12754418]
13. Negrisanu G, Rosu M, Bolte B, Lefter D, Dabelea D Effects of 3month treatment with the antioxidant alpha-lipoic acid in diabetic
peripheral neuropathy. Rom J Intern Med. 1999 Jul-Sep;37(3):297-306
[PMID: 15532308]
14. de Champlain J. et.al. Oxidative stress in hypertension. Clin Exp
Hypertens. 2004 Oct-Nov; 26 (7-8): 593-601 [PMID: 15702613]
15. Preuss HG, Bagchi M. Protective effects of novel niacin-bound
chromium complex and a grape seed proanthocyanidin extract on
advancing age and various aspects of syndrome X. Ann NY Acad Sci.
2002 May; 957:250-9. [PMID: 12074977]
These statements have not been evaluated by the
Food and Drug Administration. This product is not
intended to diagnose, treat, cure, or prevent any disease.
Manufactured for:
PCCA
9901 S. Wilcrest Dr.
Houston, TX 77099
281.933.6948
CoEnzyme-B provides the “activated” form of the Bvitamins for enhanced bioavailability to assist in the many
biochemical pathways requiring these nutrients.
B-vitamins are required for numerous biochemical and
physiological processes including the metabolism of
macronutrients (carbohydrates, fats and proteins) to make
energy, support of healthy nervous system function and
for cardiovascular function. Typically B-vitamins are used
as needed and any excess is excreted. This makes it very
important to consume these essential nutrients on a daily
basis. Once B-vitamins are consumed they cannot perform
their necessary functions until they are converted into
their active coenzyme forms. Aging, chronic disease and
other factors may limit one’s ability to convert B-vitamins
into their coenzyme forms. CoEnzyme-B provides the
active, coenzymated forms of the essential B-vitamins that
do not require metabolic conversion, and therefore may
offer an advantage to certain populations such as the
elderly, those with malabsorption issues, metabolic
diseases such as diabetes, and many others.
PABA ................................................................... 25 mg
Cocarboxylase (coenzyme vitamin B-1) ................. 5 mg
Riboflavin-5-phosphate (coenzyme vitamin B-2) ... 5 mg
Pantethine (coenzyme vitamin B-5) ........................ 5 mg
Pyridoxal-5-phosphate (coenzyme vitamin B-6) .... 5 mg
Methylcobalamin (coenzyme vitamin B-12) ........ 25 mcg
Dibencozide (coenzyme vitamin B-12) ............... 25 mcg
Adults take one (1) vegetarian capsule daily or as directed
by a healthcare professional.
Generally well tolerated. Upset stomach may result from
consuming concentrated forms of B-vitamins. Please
consult with a healthcare professional before taking
CoEnzyme B if you are pregnant or breastfeeding, or on
medications that may interact with B-vitamins.
Store in a cool, dry place, away from direct light. Keep
out of reach of children.
Contains No Added sugar, salt, dairy, yeast, wheat, corn,
soy, preservatives, artificial colors or flavors.
CoEnzyme-B may be a useful dietary supplement for
those who wish to increase their intake of the B-vitamins
in a readily absorbable and more bioavailable form.
Berdanier, C., Zempleni, J. Advanced Nutrition: Macronutrients,
Micronutrients, and Metabolism. CRC Press; 2000
Gropper, S., Smith J. Advanced Nutrition and Metabolism. Wadsworth;
2009.
Vitamin B-1 (as thiamin HCL).......................... ....50 mg
Vitamin B-2 (as riboflavin) ................................... 50 mg
Niacin (as niacinamide) ....................................... 50 mg
Vitamin B-6 (as pyridoxine HCl) .......................... 50 mg
Vitamin B-12 (as cyanocobalamin)......................50 mcg
Folate (as folic acid) ..........................................800 mcg
Biotin .................................................................200 mcg
Pantothenic Acid (as d-calcium pantothenate) ...... 50 mg
Choline (as choline bitartrate) ............................... 25 mg
Inositol .................................................................. 25 mg
These statements have not been evaluated by the
Food and Drug Administration. This product is not
intended to diagnose, treat, cure, or prevent any disease.
Manufactured for:
PCCA
9901 S. Wilcrest Dr.
Houston, TX 77099
281.933.6948
Turmeric is a traditional Indian culinary spice and
Ayurvedic medicine that has been utilized for a wide array
of medicinal purposes. Its most common traditional use
has been to promote proper digestion. Even the German
Commission E Monograph on turmeric describes it as an
approved medicinal herb for dyspeptic (indigestion)
conditions. In the last decade, turmeric has received
tremendous attention and numerous clinical studies have
confirmed its health-promoting effects and specifically
supporting a healthy inflammatory response.
Antioxidant nutrients are necessary to protect the body
from the destructive effects of harmful molecules that
cause oxidation. Because these molecules are highly
reactive, they are called reactive species and have a strong
tendency to grab an electron from other molecules and
damage delicate cellular structures, unsaturated fatty acids
and even DNA. Thus, the role of antioxidants is to prevent
this damage by balancing the pro-oxidative/anti-oxidative
states of the body. Oxidative stress is a term given when
oxidation outpaces the body’s ability to neutralize free
radicals and is a key factor in the inflammatory process.
These reactive radicals and oxidants may injure cells and
tissue directly via oxidative degradation as well as injure
cells indirectly by altering signaling processes that exist
within the tissue to be pro-inflammatory. Antioxidants
may help play a role in regulating inflammation by
neutralizing free radicals and contributing to a normal and
healthy inflammatory response.
Turmeric contains a group of compounds called
curcuminoids that have shown to possess potent
antioxidant properties. Curcumin is the main yellow
constituent of turmeric and most biologically active as a
potent antioxidant. Curcuminoids have also been shown to
inhibit the metabolism of arachidonic acid (a proinflammatory fatty acid) by inhibiting cyclooxygenase-2
(COX-2) and lipoxygenase enzymes. Collectively,
turmeric’s ability to support a healthy inflammatory
response is a function of its antioxidant properties and
inhibitory effect on mechanisms that support
inflammation. Curcumin Complex features Sabinsa’s
Curcumin C3 Complex®; made up of three main chemical
compounds: curcumin, demethoxycurcumin and
bisdemethoxycurcumin, collectively known as
curcuminoids.
Curcumin C3 Complex was the only turmeric chosen by
the National Cancer Institute (NCI) for clinical studies.
Curcumin Complex may be a useful dietary supplement
for those who wish to help support a healthy, normal
inflammatory response.
Turmeric Root Extract ........................................ 500 mg
(Curcuma longa) (standardized to 95% [475 mg]
curcuminoids)
Other Ingredients: Capsule (cellulose, water), magnesium
stearate and silica.
Contains No sugar, salt, dairy, yeast, wheat, gluten, corn,
soy, preservatives, artificial colors or flavors.
As a dietary supplement, adults take one (1) vegetarian
capsule daily, or as directed by a healthcare professional.
Generally regarded as safe. Please consult with a
healthcare professional before taking Curcumin Complex
if you have gallstones or complications associated with
the gallbladder or are taking blood thinners. Curcumin
Complex may inhibit cytochrome P450 enzyme and affect
the metabolism of certain medications.
Store in a cool, dry place, away from direct light. Keep
out of reach of children.
Conner EM, Grisham MB. Inflammation, free radicals, and antioxidants.
Nutrition. 1996 Apr;12(4):274-7.
Kuhn MA, Winston D: Herbal Therapy and Supplements: A Scientific &
Traditional Approach. New York: Lippincott; 2001:330-335.
Kohli K, Ali J, Ansari MJ, Raheman Z: Curcumin: a natural
antiinflammatory agent. Indian J Pharmacol 2005, 37:141-147.
Shakibaei M, John T, Schulze-Tanzil G, Lehmann I, Mobasheri A:
Suppression of NF-κB activation by curcumin leads to inhibition of
expression of cyclo-oxygenase-2 and matrix matalloproteinase-9 in
human articular chondrocytes; Implications for the treatment of
osteoarthritis.Biochem Pharmacol 2007, 73:1434-1445.
Nita CW: Safety and anti-inflammatory activity of curcumin: a
component of turmeric (Curcuma longa). J Alternative Complementary
Med 2003, 9:161-168.
Priyadarsini KI, Maity DK, Naik GH, Kumar MS, Unnikrishnan MK,
Satav JG, Mohan H: Role of phenolic O-H and methylene hydrogen on
the free radical reactions and antioxidant activity of curcumin. Free Rad
Biol Med 2003, 35:475-484.
Volak LP, Ghirmai S, Cashman JR, Court MH. Curcuminoids inhibit
multiple human cytochromes P450, UDP-glucuronosyltransferase, and
sulfotransferase enzymes, whereas piperine is a relatively selective
CYP3A4 inhibitor. Drug Metab Dispos. 2008.
These statements have not been evaluated by the
Food and Drug Administration. This product is not
intended to diagnose, treat, cure, or prevent any disease.
Manufactured for:
PCCA
9901 S. Wilcrest Dr.
Houston, TX 77099
281.933.6948
DIM Enhanced is a microencapsulated form of
diindolylmethane, with curcumin, green tea, and wasabia
designed to support healthy hormone balance and immune
health. Microencapsulated DIM by BioResponse® is a
patented, absorption-enhancing formulation to ensure
proper assimilation by the body.
Diindolylmethane
During the body’s natural detoxification processes,
potentially detrimental molecules such as hormone
metabolites, alcohol, drugs and air pollutants are removed
from the blood stream via the liver. Healthy hormone
detoxification is a crucial part of the normal functioning
of the immune system.
Diindolylmethane (DIM) is one molecule known for the
supportive role it plays in stimulating natural
detoxification enzymes and supporting normal hormone
metabolism. As a natural component derived from indole3-carbinole and cruciferous vegetables, DIM has shown in
studies to support the 2-hydroxylation instead of 16hydroxylation of certain estrogen metabolites. This favors
the production of 2-hydroxysterone over the more
deleterious 16-hydroxyestrone. Other studies indicate that
diindolylmethane may play important roles in inducing
apoptosis and supporting the body’s normal angiogenic
balance, especially in regards to healthy breast, cervical
and prostate cells.
Microencapsulated DIM is the only diindolymethane
with proven absorption and activity demonstrated in
independently performed clinical studies. BioResponse
DIM contains pure DIM, microencapsulated in particles
complexed with a vitamin E derivative and phospholipids
to aid absorption from our intestinal tract. The patented
formulation process for making BioResponse DIM creates
microparticles of DIM, emulsifies the DIM with vitamin E
and phospholipids, and captures these complexes through
a drying process in larger particles of pure food starch.
The result is a sustained-release, dry powder which redissolves easily after oral consumption.
Green Tea
Scientists have identified numerous phytochemicals
including polyphenols, methylxanthines, flavonoids, and
triterpenoid saponins in green tea. The polyphenols
contained in tea, specifically the catechins, appear to
provide the primary health promoting benefits associated
with green tea consumption. Catechin, epicatechin,
epigallocatechin (EGC), and most notably EGCG,
epigallocatechin gallate act as antioxidants and support
immune function and liver detoxification. Additionally, in
vitro, these nutrients have been shown to support healthy
cell growth and division.
MERIVA® Curcumin
Studies have shown that curcumin, a naturally occurring
biologically active group of compounds from Curcuma
longa (turmeric), can function as efficient antioxidants
and can help regulate the body’s normal response to
inflammatory processes. Curcumin can also play an
important role in maintaining healthy angiogenic balance
and help to support the body’s detoxification processes.
Since curcumin exhibits poor oral absorption in the body,
we have chosen a highly bioavailable curcumin called
MERIVA. Pharmacokinetic comparison studies have
shown MERIVA to have up to a 20-fold improvement in
bioavailability versus the standard 95% turmeric extracts
due to proprietary PHYTOSOME technology which
increases hydrolytic stability.
Wasabia Japonica
Wasabia, a member of the cruciferous vegetable family,
contains long chain isothiocyanates (ITCs). These ITCs
are believed to be 10-25 times more potent in the
detoxification process than most ITCs found in
cruciferous vegetables. These long chain ITCs are unique
to wasabia and are not commonly found in other
cruciferous vegetables.
DIM® Enhanced may be a useful dietary supplement for
individuals wishing to support healthy estrogen
detoxification, hormone balance and immune support.
MERIVA® Curcumin Phytosome ................... 125 mg
(Curcuma longa extract, rhizome/Phosphatidylcholine [soy]
complex)
Green tea extract (leaf) ............................ …….200 mg
(standardized to 95% polyphenols and 45% EGCG)
BioResponse DIM® complex ........................... 125 mg
(complex of starch, diindolylmethane,d-alpha tocopheryl
succinate, phosphatidylcholine [soy] and silica),
(standardized to contain 25% diindolylmethane)
Wasabia japonica (rhizome) .............................. 50 mg
(containing at least 1,200 mcg of isothiocyantes as allyl ITC,
3-butenyl ITC, and 4-pentyl ITC)
BioResponse DIM® is a trademark of BioResponse, L.L.C., Boulder.
stimulate apoptosis and confer protection against DNA damage in human
colon cell lines. Cancer Res 2001 Aug 15;61(16):6120-30.
Chen DZ, Qi M, Auborn KJ, Carter TH. Indole-3-carbinol and
diindolylmethane induce apoptosis of human cervical cancer cells and in
murine HPV16-transgenic preneoplastic cervical epithelium. J Nutr 2001
Dec;131(12):3294-302.
Dalessandri KM, Firestone GL,
Fitch MD, Bradlow HL, Bjeldanes LF. Pilot study: effect of 3,3'diindolylmethane supplements on urinary hormone metabolites in
postmenopausal women with a history of early-stage breast cancer. Nutr
Cancer. 2004;50(2):161-7.
Fujiki H et al. Cancer inhibition by green tea. Mutat Res 1998;402(12):307-10.
Marczylo T., Verschoyle R., Cooke D., Morazzoni P., Steward W.,
Gescher A. Comparison of systemic availability of curcumin with that of
curcumin formulated with phosphatidylcholine. Chemother. Pharmacol.
2007, 60, 171-177.
Maheshwari RK, Singh AK, Gaddipati J, Srimal RC. Multiple biological
activities of curcumin: A short review. Life Sci. 2006 Jan 12Morimitsu
Y, Hayashi K, Nakagawa Y, Horio F, Uchida K, Osawa T. Antiplatelet
and anticancer isothiocyanates in Japanese domestic horseradish, wasabi.
Biofactors,. 2000;13(1-4):271-6.
CO. U.S. Patent 6,086,915.
Meriva® is a registered trademark of Indena S.p.A, Milano.
Adults take 1-2 capsules daily with food, in divided doses,
or as directed by your healthcare professional.
Avoid this product if pregnant or lactating. If taking
prescription blood thinners such as Coumadin (warfarin)
consult your physician prior to use.
Women: 100-200 mg BioResponse DIM (25-50 mg DIM)
Men: 200-400 mg BioResponse DIM (50-100 mg DIM)
Harmless changes in urine color may occur if less than
recommended daily water intake is consumed.
Store in a cool, dry place, away from direct light. Keep
out of reach of children.
Zeligs MA, Diet and estrogen status: the cruciferous connection. J of
Medicinal Food 1998 Nov 2; 1: 67-82.
Zeligs MA, Jacobs I, Facilitated absorption of a hydrophobic dietary
supplement. Controlled Release Society Proceedings 1999: in press.
Bradlow HL, et al., 2-hydroxyestrone: the 'good' estrogen. J Endocrinol.
1996 Sep; 150 Suppl:S259-65.
Bradlow HL, et al., 16a hydroxylation of estradiol: a possible risk marker
for breast cancer. Annals NY Acad. Sci. 1986; 464: 138-151.
Bonnesen C, Eggleston IM, Hayes JD. Dietary indoles and
isothiocyanates that are generated from cruciferous vegetables can both
These statements have not been evaluated by the
Food and Drug Administration. This product is not
intended to diagnose, treat, cure, or prevent any disease.
Manufactured for:
PCCA
9901 S. Wilcrest Dr.
Houston, TX 77099
281.933.6948
FOS Powder supplies 3,000 mg of fructooligosaccharides
per serving.
Prebiotics are carbohydrates that have short molecular
chains. They function as non-digestible ingredients that
can positively affect selected groups of beneficial
intestinal microflora, such as lactobacillus. While
probiotics merely add beneficial microflora, prebiotics
affect the intestinal environment so that beneficial
colonies of microflora can flourish. By aiding the
beneficial microflora’s survival, pathogenic microflora
can have a decreased chance of survival.
Cummings JH, Macfarlane GT, Englyst HN. Prebiotic digestion and
fermentation. Am J Clin Nutr 2001 Feb;73(2 Suppl):415S-420S
Luo J, Van Yperselle M, Rizkalla SW, Rossi F, Bornet FR, Slama G.
Chronic consumption of short-chain fructooligosaccharides does not
affect basal hepatic glucose production or insulin resistance in type 2
diabetics. J Nutr 2000 Jun;130(6):1572-7
Prosky L. When is dietary fiber considered a functional food? Biofactors
2000;12(1-4):289-97
Roberfroid MB. Chicory fructooligosaccharides and the gastrointestinal
tract. : Nutrition 2000 Jul-Aug;16(7-8):677-9
Tuohy KM, Kolida S, Lustenberger AM, Gibson GR. The prebiotic
effects of biscuits containing partially hydrolysed guar gum and fructooligosaccharides - a human volunteer study. Br J Nutr 2001
Sep;86(3):341
FOS powder may be a useful dietary supplement for
individuals wishing to support their gastrointestinal
system.
Calories ....................................................................... 20
Total Carbohydrates ................................................ 4 gm
Dietary Fiber ....................................................... 3 gm
Soluble Fiber ........................................................ 3 gm
Sodium .................................................................. 20 mg
Ingredients: Partially Hydrolyzed Guar Gum (natural
fiber). Contains No sugar, salt, dairy, yeast wheat, gluten,
corn, soy, preservatives, artificial colors or flavors.
As a dietary supplement, adults mix one (1) tablespoon
into 4 oz. or more of liquid or soft food. Stir until mixed.
Do not use in carbonated beverages.
No adverse effects have been reported.
Store in a cool, dry place, away from direct light. Keep
out of reach of children.
These statements have not been evaluated by the
Food and Drug Administration. This product is not
intended to diagnose, treat, cure, or prevent any disease.
Manufactured for:
PCCA
9901 S. Wilcrest Dr.
Houston, TX 77099
281.933.6948
Glutamine Plus four focused ingredients – glutamine,
arabinogalactan, aloe vera and deglycyrrhized licorice – to
optimally support gastrointestinal health including growth
of the mucosal lining, promotion of gut microflora and
beneficial short-chain fatty acid production.
bulk and normalize stool bacteria where high levels of
yeasts previously existed.[4] The aloe extract used in
Glutamine Plus does not have a laxative effect because the
bitter principles have been removed.
Glutamine Plus may be a useful dietary supplement for
individuals wishing to support gastrointestinal health.
L-Glutamine, the most abundant free form amino acid in
the body, is very important for maintaining
gastrointestinal and stimulated immune cell functioning. It
is an important transporter of nitrogen (and carbon) in the
body and therefore, is vital in wound healing. Although
glutamine can be synthesized by the intestinal mucosa,
during periods of physiological stress when needs cannot
likely be met by the body alone, gut epithelial atrophy,
ulceration and even necrosis are possible.[1] L-glutamine
is metabolized to ammonia and glutamate.
Arabinogalactan, a polysaccharide derived from the Larch
tree, contributes fermentable fiber to this formula in
addition to having immuno-stimulatory properties. It
minimizes ammonia synthesis and absorption, enhances
production of short chain fatty acids and increases the gut
microflora population.[2]
Licorice Root Extract 10:1(deglycyrrhized) is a
concentrated extract that has been processed to remove
glycyrrhizin, thus eliminating any risk of licoriceassociated side effects. It is anti-inflammatory,
antispasmotic and has laxative and soothing effects.
Aspirin-induced mucosal damage has been shown to be
reduced by administration of deglycyrrhized licorice.[3]
Aloe Leaf Extract (standardized to 50% polysaccharides),
used for thousands of years, is perhaps most well-known
for healing of damaged epithelial tissue, including the
bowel lining. Despite the lack of scientific published
studies there is anecdotal evidence to suggest that aloe
vera helps inflammatory conditions of the gastrointestinal
tract. In some individuals it may increase G.I. transit time,
improve protein digestion and absorption, increase stool
These statements have not been evaluated by the
Food and Drug Administration. This product is not
intended to diagnose, treat, cure, or prevent any disease.
L-Glutamine ..................................................... 3,000 mg
Arabinogalactan ............................................... 2,000 mg
Licorice Root Extract 10:1(deglycyrrhizinated) . 500 mg
Aloe Leaf Extract ................................................ 100 mg
(Standardized to 50% [50 mg] polysaccharides)
Other Ingredients: Stevia.
Mix one scoop in 2-4 oz. water one to three times daily or
as directed by a healthcare professional.
No adverse effects have been reported.
Store in a cool, dry place, away from direct light. Keep
out of reach of children.
1. L-Glutamine. www.naturaldatabase.com {accessed 4.3.07}
2. Arabinogalactan. www.naturaldatabase.com {accessed 4.3.07}
3. Rees WD, et al. Effect of deglycyrrhizinated liquorice on gastric
mucosal damage by aspirin. Scand J Gastroenterol. 1979;14(5):605-7.
[PMID: 493863]
4. Davis K, et. al. Randomised double-blind placebo-controlled trial of
aloe vera for irritable bowel syndrome. Int J Clin Pract. 2006
Sep;60(9):1080-6 [PMID: 16749917]
Manufactured for:
PCCA
9901 S. Wilcrest Dr.
Houston, TX 77099
281.933.6948
Supplies significant amounts of indole-3-carbinol (I-3-C)
in a proprietary blend of cruciferous vegetables for
healthy hormone balance and cellular health
Adults take 1-2 capsules daily in divided doses with meals
or as directed by a healthcare professional.
WARNING: Women who are breastfeeding or pregnant
should not take this product.
Indole-3-carbinol is a member of the class of sulfurcontaining chemicals called glucosinolates,
phytochemicals found in high amounts in cruciferous
vegetables such as broccoli, cauliflower, and Brussels
sprouts. Indole-3-carbinol functions as an antioxidant,
stimulates natural detoxification enzymes and supports
normal hormone metabolism. † Furthermore, I-3-C
supports the function of healthy breast and cervical cells.
† In recent years, I-3-C has shown a promising ability to
support prostate cell metabolism.
In the stomach, indole 3-carbinol must be broken down
into its active metabolite diindolylmethane, another indole
compound that also has similar health benefits. Indole-3carbinol supports healthy estrogen metabolism by
promoting a healthy ratio of weak estrogens (2hydroxyestone metabolites or 2-OHE) to strong estrogens
(16 alpha-hydroxyestrone metabolites or 16 alpha-OHE)
in favor of the weak, less potent estrogens. Indole-3carbinol also induces phase II enzymes including
glutathione S-transferase (GST). Cruciferous vegetables
like broccoli and cauliflower offer protective sulforophane
compounds known for their ability to induce protective
detoxifying enzymes.
Indole-3-Carbinol may be a useful dietary supplement for
individuals wishing to supplement their diet with indole-3carbinol to support healthy estrogen metabolism.
No adverse side effects reported.
The conversion of I-3-C to its active metabolites requires
stomach acid. Therefore, antacids, H2 blockers, and
proton-pump inhibitors may impede its effectiveness.
Refrigeration is suggested for this product.
Store in a cool, dry place, away from direct light. Keep
out of reach of children.
Bonnesen C, Eggleston IM, Hayes JD. Dietary indoles and
isothiocyanates that are generated from cruciferous vegetables can both
stimulate apoptosis and confer protection against DNA damage in human
colon cell lines. Cancer Res 2001 Aug 15;61(16):6120-30.
Chen DZ, Qi M, Auborn KJ, Carter TH. Indole-3-carbinol and
diindolylmethane induce apoptosis of human cervical cancer cells and in
murine HPV16-transgenic preneoplastic cervical epithelium. J Nutr 2001
Dec;131(12):3294-302.
Frydoonfar HR, McGrath DR, Spigelman AD. The effect of indole-3carbinol and sulforaphane on a prostate cancer cell line. ANZ J Surg 2003
Mar;73(3):154-6.
McAlindon TE, Gulin J, Chen T, Klug T, Lahita R, Nuite M. Indole-3carbinol in women with SLE: effect on estrogen metabolism and disease
activity. Lupus 2001;10(11):779-83.
Nho CW, Jeffery E. The synergistic upregulation of phase II
detoxification enzymes by glucosinolate breakdown products in
cruciferous vegetables. Toxicol Appl Pharmacol 2001 Jul 15;174(2):14652.
Indole-3-Carbinol................................................ 200 mg
Proprietary Blend ................................................ 100 mg
Standardized Broccoli, Cauliflower and Brussels Sprout
These statements have not been evaluated by the
Food and Drug Administration. This product is not
intended to diagnose, treat, cure, or prevent any disease.
Manufactured for:
PCCA
9901 S. Wilcrest Dr.
Houston, TX 77099
281.933.6948
Inositol Powder provides 500 milligrams per serving of
pure inositol powder. Its slightly sweet flavor makes it
easy to mix into water and drinks.
Store in a cool, dry place, away from direct light. Keep
out of reach of children.
Although inositol has been referred to as “vitamin B-8,” it
is not classified as a vitamin because humans can
synthesize it from glucose. Other names include
hexahydroxycyclohexane or cyclohexanehexol. It is a
component of every cellular membrane in the body and
particularly concentrated in the heart and brain. It is
specifically found in the phospholipids of cellular
membranes and plays critical roles in several biochemical
pathways, including acting as cellular mediators of signal
transduction, metabolic regulation, and growth. It
contributes to the function of nerves and muscles and
helps the liver process fats. There is some evidence to
suggest that inositol may help support a healthy mood for
those people suffering from panic disorders or for people
under stress.
Palatnik A, Frolov K, Fux M, Benjamin J (2001). "Double-blind,
controlled, crossover trial of inositol versus fluvoxamine for the treatment
of panic disorder". Journal of Clinical Psychopharmacology 21 (3): 335–
339.
Levine J, Barak Y, Gonzalves M, Szor H, Elizur A, Kofman O, Belmaker
RH. (1995). "Double-blind, controlled trial of inositol treatment of
depression". American Journal of Psychiatry 152 (5): 792–794.
Inositol Powder is a useful dietary supplement for
maintaining normal cellular processes as well as helping
support a healthy mood for those suffering from panic
disorder or for people under stress.
Inositol ................................................................ 500 mg
Contains no added sugar, salt, dairy, yeast, wheat, soy,
preservatives, artificial colors or flavors.
As a dietary supplement, adults take 1/4 teaspoon in eight
(8) ounces of water or juice daily, or as directed by a
healthcare professional.
Please consult with a healthcare professional before taking
Inositol if you are taking medications for depression or
mood disorders.
These statements have not been evaluated by the
Food and Drug Administration. This product is not
intended to diagnose, treat, cure, or prevent any disease.
Manufactured for:
PCCA
9901 S. Wilcrest Dr.
Houston, TX 77099
281.933.6948
Ipriflavone capsules contain 300 mg of ipriflavone, a type
of isoflavone. Isoflavones are one of many classes of
flavonoids, phytochemicals widely recognized and studied
for their numerous health benefits.
Ipriflavone helps promote bone density by inhibiting bone
resorption. Numerous studies of postmenopausal women
and individuals whose bones are showing signs of
demineralization have investigated the benefits of
ipriflavone on bone health. Laboratory and clinical studies
have documented ipriflavone’s positive effect on bone
density.
Experts agree that ipriflavone appears to directly inhibit
osteoclast activity, thereby decreasing bone resorption.
Osteoclasts and osteoblasts are two primary types of bone
cells. Osteoblasts, the more exterior cells, are responsible
for bone mineralization. Osteoclasts, found beneath the
osteoblasts, are responsible for bone resorption. When
calcium levels in the blood drop, the osteoblasts change
shape, allowing the osteoclasts to become exposed and
release calcium from the bones to the rest of the body.
Scientists suspect ipriflavone may also stimulate
osteoblast activity. Since osteoblasts are responsible for
laying down new bone, an increase in osteoblast activity
would result in increased bone mineralization. This
suggests Ipriflavone may not only inhibit the breakdown
of existing bone, but also encourage the formation of new
bone.
Bone is constantly turning over in a continuous process of
formation and resorption. During certain stages of life, the
balance between bone mineralization and resorption may
be tipped. During childhood and adolescence, while the
body is growing, bone mineralization generally exceeds
bone resorption. Once one reaches peak bone mass,
sometime between the age of 20 and 30, bone formation
slows down. For many, bone resorption begins to prevail
over bone formation, beginning the cycle of progressive,
age-associated bone demineralization.
In women, bone loss is generally accelerated following
menopause. The decline in estrogen levels associated with
menopause appears to put women at increased risk for
declining bone density and osteoporosis.
Osteoporosis affects a large proportion of postmenopausal
women and the elderly in developed countries. For some
women, exogenous hormones provide some continued
protection against accelerated, progressive,
postmenopausal bone loss. Currently, there are few
effective options for those women who are unable to, or
choose not to take hormone replacement therapy (HRT).
Ipriflavone, together with adequate calcium, vitamin D,
and other key nutrients in bone health, offers
nonestrogenic protection against excessive bone
resorption. Unlike other well-known isoflavones, such as
genistein found in soy foods, ipriflavone does not have
estrogenic activity. Ipriflavone can be safely used in
conjunction with natural phytoestrogens or with HRT.
Further, ipriflavone provides a positive effect on bone
health in women for whom hormone therapies are
contraindicated.
Ipriflavone may be a beneficial dietary supplement for
postmenopausal women, those at risk for osteoporosis, or
anyone concerned about bone health.
Ipriflavone ........ ..................................................300 mg
One capsule twice daily as a dietary supplement, or as
directed by a physician.
No adverse effects have been reported.
Store in a cool, dry place, away from direct light. Keep
out of reach of children.
Adami S, Bufalino L, Cervetti R, et al. Ipriflavone prevents radical bone
loss in postmenopausal women with low bone mass over 2 years.
Osteoporosis Int 1997;7(2):119-25.
Agnusdei D, Bufalino L. Efficacy of ipriflavone in established
osteoporosis and long-term safety. Calcif Tissue Int 1997;61 Suppl
1:S23-7.
Agnusdei D, Crepaldi G, Isaia G, et al. A double blind, placebocontrolled
trial of ipriflavone for prevention of postmenopausal spinal bone loss.
Calcif Tissue Int 1997;61(2):142-7.
Avioli LV. The future of ipriflavone in the management of osteoporotic
syndromes. Calcif Tissue Int 1997;61 Suppl 1:S33-5.
Cecchettin M, Bellometti S, Cremonesi G, et al. Metabolic and bone
effects after administration of ipriflavone and salmon calcitonin in
postmenopausal osteoporosis. Biomed Pharmacother 1995;49(10):465-8.
Cheng SL, Zhang SF, Nelson TL, et al. Stimulation of human osteoblast
differentiation and function by ipriflavone and its metabolites. Calcif
Tissue Int 1994;55(5):356-62.
Choi YK, Han IK, Yoon HK. Ipriflavone for the treatment of
osteoporosis. Osteoporosis Int 1997;7 Suppl 3:S174-8.
Civitelli R. In vitro and in vivo effects of ipriflavone on bone formation
and bone biomechanics. Calcif Tissue Int 1997;61 Suppl 1:S12-14.
de Aloysio D, Gambacciani M, Altieri P, et al. Bone density changes in
postmenopausal women with the administration of ipriflavone alone or in
association with low-dose ERT. Gynecol Endocrinol 1997;11(4):289-93.
Gambacciani M, Ciaponi M, Cappagli B, et al. Effects of combined low
dose of the isoflavone derivative ipriflavone and estrogen replacement on
bone mineral density and metabolism in postmenopausal women.
Maruritas 1997;28(1):75-81.
Gambacciani M, Spinetti A, Cappagli B, et al. Effects of ipriflavone
administration on bone mass and metabolism in ovariectomized women. J
Endocrinol Invest 1993;16(5):333-7.
Gennari C, Adami S, Agnusdei D, et al. Effect of chronic treatment with
ipriflavone in postmenopausal women with low bone mass. Calcif Tissue
Int 1997;61 Suppl 1:S19-22.
Gennari C, Agnusdei D, Crepaldi G, et al. Effect of Ipriflavone – a
synthetic derivative of natural isoflavones – on bone mass loss in the early
years after menopause. Menopause 1998;5(1):9-15.
Petilli M, Fiorelli G, Benvenuti S, et al. Interactions between ipriflavone
and the estrogen receptor. Calcif Tissue Int 1995;56(2):160-5.
Kovacs AB. Efficacy of ipriflavone in the prevention and treatment of
postmenopausal osteoporosis. Agents Actions 1994;41(1-2):86-7.
Melis GB, Paoletti AM, Cagnacci A, et al. Lack of any estrogenic effect
of ipriflavone in postmenopausal women. J Endocrinol Invest
1992;15(10):755-61.
Nakamura S, Morimoto S, Takamoto S, et al. Effect of ipriflavone on
bone mineral density and calcium-related factors in elderly females.
Calcif Tissue Int 1992;51 Suppl 1:S30-4.
Reginster JY. Ipriflavone:pharmacological properties and usefulness in
postmenopausal osteoporosis. Bone Miner 1993;23(3):223-32.
Valente M, Bufalino L, Castiglione GN, et al. Effects of 1-year treatment
with ipriflavone on bone in postmenopausal women with low bone mass.
Calcif Tissue Int 1994;54(5):377-80.
These statements have not been evaluated by the
Food and Drug Administration. This product is not
intended to diagnose, treat, cure, or prevent any disease.
Manufactured for:
PCCA
9901 S. Wilcrest Dr.
Houston, TX 77099
281.933.6948
L-Methylfolate supplies 1,000 mcg of biologically active
folate called (6S) 5-methyltetrahydrofolate (5-MTHF).
Folate is a water-soluble essential B vitamin found in
many foods, including leafy green vegetables, citrus fruits
and beans. Research has established that supplementation
with folate before and during the first two months of
pregnancy can support proper neurological development
in the fetus. Additionally, folate plays a key role in the
metabolism of homocysteine. Homocysteine is a sulfur
containing amino acid that is created in the body from
methionine, an essential amino acid derived solely from
dietary intake. High plasma levels of homocysteine appear
to injure the vasculature, impairing the functional abilities
of endothelial and smooth muscle cells.
Metafolin® folate is a patented, natural form of (6S) 5methyltetrahydrofolate (5-MTHF). 5-MTHF is the
naturally occurring, predominant form of folate commonly
found in cells and is essential for overall health, as it
participates as a cofactor in a reaction that involves the
remethylation of homocysteine to methionine. Unlike
synthetic folic acid, 5-MTHF can be used directly by the
body, without the need for an additional conversion via
the enzyme 5,10-methylenetetrahydrofolate reductase
(MTHFR). In certain populations, the body’s ability to
convert folic acid to 5-MTHF by use of this enzyme may
be compromised due to genetic differences.
Metafolin contains only the S isomer of 5-MTHF and has
been shown to be the only form of folate to be able to
cross the blood-brain barrier. Metafolin does not appear to
mask the anemia associated with a vitamin B12 deficiency
and presents no risk of an accumulation of unmetabolized
folic acid in the body.
Folate (as L-methylfolate, Metafolin®)..............1,000 mcg
Other ingredients: Cellulose, dicalcium phosphate,
croscarmellose sodium, vegetable stearate and silica
Adults take 1 tablet daily or as directed by a healthcare
professional.
Doses of 5 mg or higher per day can cause abdominal
cramps, diarrhea, and rash.
Store in a cool, dry place, away from direct light. Keep
out of reach of children.
J. Scott (2001): Methyltetrahydrofolate: The Superior Alternative to Folic
acid. Nutraceuticals in health and disease prevention, 75-90 [Krämer K,
Hoppe PP and Packer L, editors]. New York: Marcel Dekker Inc.
O. Hasselwander, W. Hönlein, L. Schweillert, K. Krömer (2000): 5Methyltetrahydrofolate: The active form of folic acid. Functional foods
2000.
Y. Smulders, D. Smith, R. Kok, T. Teerlink, D. Swinkels, C. Stehouwer,
C. Jabobs (2005): Cellular folate vitamer distribution during and after
correction of vitamin B12 deficiency: a case for the methylfolate trap.
British J. of Haematology, 132, 623-9.
S. Gutstein, L. Bernstein, L. Levy, G. Wagner (1973): Failure of response
to N5-methyltetrahydrofolate in combined folate and B12 deficiency.
Evidence in support of the “folate trap” hypothesis. Digestive diseases,
Vol. 18 (2), 142-6.
P. Kirke, L. Mills, A. Molloy, l. Brody, V. O'Leary, L. Daly, S. Murray,
M. Conley, P. Mayne, O. Smith, J. Scott (2004): Impact of the MTHFR
C677T polymorphism on risk of neutral tube defects: case-control study.
BMJ, Vol. 328, 1535-6.
L-Methylfolate is a useful dietary supplement for those
individuals that prefer a high dose active form of folic
acid called (6S) 5-MTHF.
These statements have not been evaluated by the
Food and Drug Administration. This product is not
intended to diagnose, treat, cure, or prevent any disease.
Manufactured for:
PCCA
9901 S. Wilcrest Dr.
Houston, TX 77099
281.933.6948
Male Virility Support is a proprietary male formula that
has been synergized with an herbal blend to support the
processes involved in promoting a healthy male sex drive,
energy and stamina.
Male virility and sexual health depend upon several
factors. Sex drive is influenced by the normal, healthy
production of hormones such as testosterone. Adequate
hormone production helps drive the physiological
processes involved in sexual health. The complex
relationship between hormones, enzymes and other
biochemicals must be carefully nurtured if a
psychological, physiological and anatomical balance that
supports optimal sexual health can be attained.
Several ingredients found in Male Virility Support may
help support healthy sex drive in men. The active
ingredient in horny goat weed, icariin, has been shown to
be an effective regulator of the PDE-5 (phosphodiesterase
5) enzyme. This enzyme is involved in blood vessel
dilation and circulation, both of which are critical for male
sexual health. Tribulus terrestris has been shown to
support healthy libido. Maca helps promote endurance,
energy, and vitality. Korean Ginseng is a potent adaptogen
that helps support energy and vitality. Damiana and Muira
Puama both help support libido and male vitality.
Male Virility Support may be a useful dietary supplement
for men looking to support healthy, normal sex drive,
energy and stamina.
powder, Tribulus terrestris aerial parts powder,
Damiana (Tumera diffusa) leaf powder, and Korean
Ginseng root powder.
Other Ingredients: Gelatin, water (capsule), cellulose,
stearic acid, magnesium stearate and silica. ViriloMax™
is a herbal libido formula that’s potentiated with the
proprietary T Pump herbal activator to support men’s
sexual health and normal healthy testosterone levels.
Contains No sugar, salt, dairy, yeast, wheat, gluten, corn,
soy, preservatives, artificial colors or flavors.
As a dietary supplement, men take two (2) capsules daily
with meals, or as directed by a healthcare professional.
No significant side effects noted. Please consult with a
healthcare professional before taking Male Virility
Support if you are taking blood thinners, medications for
blood pressure or heart conditions, vasodilators, or
already taking medications for erectile dysfunction.
Store in a cool, dry place, away from direct light. Keep
out of reach of children.
Chen CY, Chang YH, Bau DT, Huang HJ, Tsai FJ, Tsai CH, Chen CY.
Discovery of potent inhibitors for phosphodiesterase 5 by virtual
screening and pharmacophore analysis. Acta Pharmacol Sin. 2009
Aug;30(8):1186-94. Epub 2009 Jul 13.
Chiu JH, Chen KK, Chien TM et al. Epimedium brevicornum Maxim
extract relaxes rabbit corpus cavernosum through multitargets on nitric
oxide/cyclic guanosine monophosphate signaling pathway. Int J Impot
Res. 2006;18:335-42.
Chen KK, Chiu JH. Effect of Epimedium brevicornum Maxim extract on
elicitation of penile erection in the rat. Urology. 2006;67:631-5.
VirilomaxTM Propietary Blend ............................ 750 mg
Horny Goat Weed (Epimedium sagittatum) aerial parts
standardized to 10% icariins, Fenugreek seed extract,
and Muira Puama (Ptychopetalum olacoides) bark and
root powder.
Synergized with T Pump Herbal Activator ......... 750 mg
Kola nut seed extract, Maca (Lepidium meyenii) root
Ning H, Xin ZC, Lin G et al. Effects of icariin on phosphodiesterase-5
activity in vitro and cyclic guanosine monophosphate level in cavernous
smooth muscle cells. Urology 2006;68:1350-4.
Steels E, Rao A, Vitetta L.Physiological Aspects of Male Libido
Enhanced by Standardized Trigonella foenum-graecum Extract and
Mineral Formulation. Phytother Res. 2011 Feb 10.
Piato AL, Detanico BC, Linck VM, Herrmann AP, Nunes DS,
Elisabetsky E. Anti-stress effects of the "tonic"Ptychopetalum olacoides
(Marapuama) in mice. Phytomedicine. 2010 Mar;17(3-4):248-53. Epub
2009 Aug 13.
Gonzales GF. Ethnobiology and Ethnopharmacology of Lepidium
meyenii (Maca), a Plant from the Peruvian Highlands. Evid Based
Complement Alternat Med. 2012;2012:193496. Epub 2011 Oct 2.
Stone M, Ibarra A, Roller M, Zangara A, Stevenson E. A pilot
investigation into the effect of maca supplementation on physical activity
and sexual desire in sportsmen. J Ethnopharmacol. 2009 Dec
10;126(3):574-6. Epub 2009 Sep 23.
Singh S, Nair V, Gupta YK. Evaluation of the aphrodisiac activity of
Tribulus terrestris Linn. in sexually sluggish male albino rats. J
Pharmacol Pharmacother. 2012 Jan;3(1):43-7.
Arletti R, Benelli A, Cavazzuti E, Scarpetta G, Bertolini A. Stimulating
property of Turnera diffusa and Pfaffia paniculata extracts on the sexualbehavior of male rats. Psychopharmacology (Berl). 1999 Mar;143(1):159.
Huang L, Zhao H, Huang B, Zheng C, Peng W, Qin L. Acanthopanax
senticosus: review of botany, chemistry and pharmacology. Pharmazie.
2011 Feb;66(2):83-97.
These statements have not been evaluated by the
Food and Drug Administration. This product is not
intended to diagnose, treat, cure, or prevent any disease.
Manufactured for:
PCCA
9901 S. Wilcrest Dr.
Houston, TX 77099
281.933.6948
phosphatase in human bone cells.[6]
MCHC Plus is an encapsulated comprehensive bone
support formula. Microcrystalline hydroxyapatite
concentrate (MCHC) contributes calcium, phosphorus,
organic factors and protein matrix, bone-derive growth
factors, and a full spectrum of trace minerals that naturally
comprise healthy bone. Additional calcium and
magnesium are in the form of highly absorbable, Albion®patented, totally reacted, malate containing chelates.
Vitamin D is as cholecalciferol. Independent third party
assays document freshness and purity of every batch.
A randomized-controlled study concluded the
combination of ossein hydroxyapatite (“OHC”, generic
Product Name) and HRT increased vertebral bone mass in
postmenopausal women to a greater extent (4.7%, P<.01)
than did HRT alone.[1] Another randomized-controlled
study divided 60 postmenopausal women not on HRT into
three groups. One group did not receive any treatment,
one received calcium carbonate(CC), and the third
received OHC. Subjects on OHC therapy did not show
significant changes from baseline bone density; density
decreased significantly in the CC group during the second
year and decreased in the control group at the first and
second bone mineral density measurement.[2] Yet another
double-blind study showed OHC is more effective than
CC in slowing peripheral trabecular bone loss in patients
with manifest osteoporosis.[6] The bioavailability of
calcium in ossein-mineral complex was also proven to be
as good as, if not better than, that of Ca-gluconate.[3]
Two randomized clinical trials demonstrated MCHC Plus
is well-tolerated and prevents the onset or progression of
osteoporosis in patients treated with corticosteroids.[4,5]
Only two subjects out of 19 subjects who reported back
pain at the beginning of a study still had any complaint
after the 12-month trial on MCHC Plus.[4]
Unlike other calcium supplements on the market, MCHC
Plus consists of collagenous and non-collagenous
proteins/peptides that contain insulin-like growth factor I
(IGF-I), insulin-like growth factor II (IGF-II),
transforming growth factor beta (TGF-beta) and
osteocalcin. These factors stimulate the activity of alkaline
Calcium absorption in the intestines is stimulated by
Vitamin D, likely deficient in the American
diet/lifestyle.[7] The normal aging process in combination
with a Vitamin D insufficiency may lead to secondary
hyperparathyroidism in the elderly, a condition that
facilitates bone loss. MCHC Plus contains Vitamin D3, a
pre-formed source of Vitamin D activity. Dietary
magnesium deficiency has been linked to Osteoporosis.
MCHC Plus contains magnesium in a 2:1 ratio with
calcium. The malates do not react with stomach acid and
are less likely than carbonates to cause gas and acid
rebound.[8]
MCHC Plus may be a useful dietary supplement for
individuals wishing to support bone density/integrity.
Vitamin D (as cholecalciferol) ........................... 100 I.U.
Calcium (from MCHC and dicalcium malate) .... 400 mg
Magnesium ......................................................... 200 mg
MicroCrystalline Hydroxyapatite Concentrate 1,000 mg
Other Ingredients: HPMC (capsule), stearic acid and
magnesium stearate.
Adults take 2 capsules twice daily or as directed by a
healthcare professional.
No adverse effects have been reported.
Store in a cool, dry place, away from direct light. Keep
out of reach of children.
1. Castelo-Branco C, Martinez de Osaba MJ, Pons F, Casals E, Sanjuan
A, Vicente JJ, Vanrell JA. Osseinhydroxyapatite compounds for
preventing postmenopausal bone loss. Coadjuvant use with hormone
replacement therapy. J Reprod Med. 1999 Mar;44(3):241-6 [PMID:
10202741]
2. Castelo-Branco C, Pons F, Vicente JJ, Sanjuan A, Vanrell JA.
Preventing postmenopausal bone loss with osseinhydroxyapatite
compounds. Results of a two-year, prospective trial . J Reprod Med. 1999
Jul; 44 (7): 601-5. [PMID: 10442322]
3. Buclin T, Jacquet AF, Burckhardt P. [Intestinal absorption of calcium
gluconate and ossein-mineral complex: an evaluation by conventional
analyses] Schweiz Med Wochenschr. 1986 Dec 13;116(50):1780-3.
[PMID: 3026039]
4. Pines A, Raafat H, Lynn AH, Whittington J. (‘Ossopan’) in the
prevention of osteoporosis due to corticosteroid therapy. Curr Med Res
Opin. 1984;8(10):734-42 [PMID: 6373153].
5. Stellon A, Davies A, Webb A, Williams R. Microcrystalline
hydroxyapatite compound in prevention of bone loss in corticosteroidtreated patients with chronic active hepatitis. Postgrad Med J. 1985 Sep;
61 (719): 791-6. [PMID: 2997764]
6. Stepan JJ, Mohan S, Jennings JC, Wergedal JE, Taylor AK, Baylink
DJ Quantitation of growth factors in ossein-mineral-compound. Life Sci.
1991;49(13):PL79-84 [PMID: 1653384]
7. Plotnikoff GA, Quigley JM. Prevalence of severe hypovitaminosis D in
patients with persistent, nonspecific musculoskeletal pain. Mayo Clin
Proc. 2003 Dec;78(12):1463-70. [PMID: 14661675]
8. Malic acid can be the right ligand for certain applications. Albion®
Research Notes; April 2002;12(2):3
9. Product literature from Robapharm AG. 174 St Albanrheinweg CH4006 Basle Switzerland Sanofi Winthrop Lt One Onslow Street Guildford
Surrey GU1 4YS Sanofi Winthrop Ireland Ltd Pottery Road Dun
Laoghaire Ireland
10. URL:
www.2.netdoctor.co.uk/medicines/showpreparatoipn.asp?id=1959
{Accessed 27 Oct 06}
-4
These statements have not been evaluated by the
Food and Drug Administration. This product is not
intended to diagnose, treat, cure, or prevent any disease.
Manufactured for:
PCCA
9901 S. Wilcrest Dr.
Houston, TX 77099
281.933.6948
NutraLibido is an herbal-based supplement, which
combines Muira Puama, Maca, Avena Sativa, and
Ginseng to aid sexual health. NutraLibido includes Dong
Quai and Tribulus to support hormone health, while
Choline and Vitamin B5 help energy levels. Additionally,
L-Arginine, Cocoa Extract, and Ginkgo Biloba can
encourage blood circulation.
Avena Sativa: More commonly known as a cereal grain
or oats, Avena Sativa (oat plant) is cultivated worldwide.
Many nutrients are contained in Avena Sativa including
vitamins B, magnesium, iron, and zinc. It has been
suggested that Avena Sativa’s tension-relieving effects
decrease sexual ailments that are related to stress and
anxiety, 1 but research is inconclusive.
CocoActiv (Theobroma cacao L.): Theobroma cacao L.,
also known as cocoa, is cultivated in tropical regions of
Central and South America. Cocoa contains antioxidants,
including phytochemicals that are beneficial to sexual
health. 2 Furthermore, the high polyphenol content
enhances nitric oxide synthesis to improve blood
circulation throughout the body.3,4
Dong Quai: Commonly used in Chinese medicine to
balance hormones and stimulate sexual behavior, Dong
Quai is a plant that grows in the mountain regions of
Korea, Japan, and China. There is evidence that Dong
Quai increases sexual behavior, as it has been reported in
female animals.5 Yet, Dong Quai research is inconclusive.
Ginkgo Biloba: One of the oldest living trees, Ginkgo
Biloba can survive over 1,000 years and grow 120 feet.
The leaves contain two unique antioxidants, flavone
glycosides and terpene lactones, which improve
circulation and maintain the tone and elasticity of arteries
and capillaries.
One cause of impotence is poor blood circulation. Ginkgo
improves blood flow throughout the body by restoring the
nitric oxide balance.6, 19 One study observed the effects of
ginkgo on impotence among 60 patients. It was reported
that 6 to 8 weeks of ginkgo supplementation improved
blood flow in 50% of the patients.7
The improvements in nitric oxide synthesis have made
gingko a beneficial aid for restoring microcirculation and
relaxing vascular walls in older individuals with
circulation problems, including erectile ailments.8 As
individuals age, endothelial function (interior blood vessel
cells) decreases altering coronary blood flow. One study
recruited 60 healthy elderly adults to take ginkgo or a
placebo. Results indicated ginkgo increased coronary
blood flow and improved endothelial function by
increasing dilation of the arteries.9
Ginseng: Ginseng has commonly been used as an herbal
treatment in Asian medicine to treat sexual ailments.10
Several studies have found ginseng can improve libido
and sexual performance suggesting the herb’s ginsenoside
components aid the central nervous system and gonadal
tissues.23 Furthermore, ginseng increases potency by
improving nitric oxide synthesis in many organs to
stimulate tissues and increase sexual drive.11
One study gave 108 women (22-73 years old) with a low
sex drive a nutritional combination (Ginseng and other
nutrients) or a placebo. After four weeks, women taking
the nutritional formulation reported significant
improvement in sexual health, especially among pre- and
periomenopausal women.12
The effects of ginseng were observed in female rabbits
with sexual ailments. Results indicated that ginseng was a
therapeutic treatment for relaxing the vaginal smooth
muscle tissue concluding this action was mediated by
nitric oxide synthesis.13 Another study found that male rats
taking ginseng had an increase in mating behavior, when
compared to the controlled group.14
L-Arginine: L-Arginine is a semi-essential amino acid
that aids nitric oxide synthesis by increasing circulation
and dilating blood vessels. In addition, it stimulates the
secretion of hormones. L-Arginine aids normal erectile
function, as it maintains nitric oxide synthesis and restores
suppressed blood circulation.15
L-Arginine can reverse the actions of NG-nitro-LArginine, a nitric oxide inhibitor. One study found the
amino acid improved oxide synthesis by relaxing the
penile small arteries to aid normal erectile function.1
A six-week study recruited 50 men with libido ailments to
take L-Arginine or a placebo. Results indicated LArginine improved erectile function in men by restoring
nitric oxide levels.16 An animal study reviewed LArginine’s effect on erectile function in rats taking the
nutrient for eight-weeks. Results indicated L-Arginine
increased nitric oxide synthesis by nearly 100% in the
treatment group to aid normal erectile function.17
Fifty patients with mild to moderate libido ailments took
an L-Arginine/Pycnogenol combination for one month
finding erectile function was restored and testosterone
levels increased in the treatment group.18
Another study recruited 45 patients to take an LArginine/Yohimbine Hydrochloride combination,
Yohimbine Hydrochloride, or a placebo. Results indicated
a significant improvement in erectile function among
patients taking the L-Arginine/Yohimbine Hydrochloride
combination, when compared to the other two groups.19
Maca Root (MacaPure®): Discovered in the Andes
mountains, Maca root has been used for generations in
Peru to improve fertility and sexual drive.
A twelve-week study gave men (21 to 56 years old) 1,500
mg of Maca, 3,000 mg of Maca, or a placebo. Subjects
taking Maca reported an increase in sexual desire, when
compared to the placebo group. Furthermore, the nutrient
did not change testosterone or estradiol levels.20
MacaPure was given to male mice with libido ailments,
observing the herb supported erectile function and
increased the number of sperm-positive female mice to
improve reproduction.21 A similar study gave female mice
Maca, finding the nutrient enhanced female fertility in the
treatment group to significantly create more offspring.22
MacaPure was also administered to female mice and male
rats. Results indicated Maca increased the number of
sperm-positive female mice and normalized erectile
function in male rats.9
Various Maca doses were compared among male rats with
erectile ailments. Researchers discovered that both an
acute (7 days) and short-term (21 days) treatment
improved sexual behavior, while long-term administration
(30 days) did not additionally enhance the benefits of an
acute or short-term dose.23
Maca may also benefit sperm activity. One study found
that sperm count increased in male rats taking Maca for
seven days, as daily sperm production began to increase
after the first day of treatment. In addition, Maca did not
increase testicular testosterone levels.24
Muira Puama: A small Brazilian tree that grows mainly
in the Amazon region, Muira Puama has a long history in
Brazilian folk medicine as an aphrodisiac to improve low
sex drive.
One study gave a Muira Puama/Ginkgo Biloba
formulation to 202 healthy women with low sex drive.
After one month of treatment, subjects noticed significant
improvement in sexual health.25 In addition, Muira Puama
has been observed to have possible stimulant activity that
improves physical and mental fatigue, without creating
These statements have not been evaluated by the
Food and Drug Administration. This product is not
intended to diagnose, treat, cure, or prevent any disease.
stress or anxiety.26
Tribulus Terrestris: Tribulus Terrestris is a vine plant
that grows in tropical, mild climates throughout the United
States, southern Asia, northern Australia, and southern
Europe. Known for its ability to increase energy and sex
drive, it is commonly used in Ayurvedic medicine.
Tribulus’ effect on erectile function was evaluated in male
rabbits and rats with erectile ailments. Results indicated
an eight-week treatment with Tribulus increased sex
hormones, including certain testosterone hormones that
help balance mild to moderate erectile ailments.27
One study found that Tribulus improved sexual behavior
in rats concluding the aphrodisiac activity may be due to
the nutrients ability to increase testosterone levels.28 The
same researchers conducted another animal study
observing the effects of Tribulus on androgen receptors in
the brain. Results indicated an eight-week treatment of
Tribulus significantly increased mechanisms associated
with androgen receptor sites to improve sexual drive.29
Similarly, Tribulus increased androgen activity and the
release of nitric oxide to improve sexual function in
rabbits taking the nutrient for eight weeks.30
NutraLibido is a specialized formulation that contains the
finest-quality, herbal ingredients to benefit sexual health.
L-Arginine HCl ................................................... 400 mg
CocoActiv™ (Cocoa) 8% Natural Theobromine . 125 mg
Macapure® (0.6% Macamides and Macaenes) .. 333 mg
Muira Puama 10:1 Extract .................................. 400 mg
Dong Quai Root (1% Ligustilide) ....................... 150 mg
Choline Bitartrate ................................................. 50 mg
Vitamin B5 (Pantothenic Acid) ............................ 50 mg
Avena Sativa 4:1 Extract .................................... 150 mg
Ginseng (min. 0.8% eleuthrosides) ....................... 40 mg
Ginkgo Biloba....................................................... 40 mg
(min. 24% ginkgo flavone glycosides, min. 6% terpene
lactones, less than 1 ppm ginkgolic acid)
Tribulus Terrestris (40% Sapponins) .................. 200 mg
As a dietary supplement, adults take 3 capsules daily, or
as directed by a healthcare professional.
The maximum safe dosages of the nutrients in this formula
have not been determined for children, pregnant or
nursing women, or those with severe liver or kidney
disease. As with all supplement regimens, please consult
Manufactured for:
PCCA
9901 S. Wilcrest Dr.
Houston, TX 77099
281.933.6948
your physician prior to use.
Avena Sativa: Individuals with gluten sensitivities should
avoid supplements with Avena Sativa.
Cocoa: There are no known adverse reactions with proper
supplementation.
Dong Quai: Possible side effects may include fever, upset
stomach, and thinning of the blood. Dong Quai should not
be used during pregnancy.
Gingko Biloba: Occasional gastrointestinal upset, allergic
skin reaction and headache. Due to its blood thinning
properties, care should be used by individuals with blood
clotting problems or those taking anticoagulant
medications.
Ginseng: Individuals with cardiovascular disease or
diabetes (may lower blood glucose levels) should use
caution when taking supplements with Ginseng.
L-Arginine: The most common adverse reactions occur at
higher doses (15 to 30 g per day), which include nausea,
diarrhea, and abdominal cramps. Pregnant and nursing
mothers should avoid L-Arginine supplementation as it
may stimulate growth hormone.
Maca Root: There are no known adverse reactions with
proper supplementation.
Muira Puama: There are no known adverse reactions
with proper supplementation.
Tribulus Terrestris: There are no known adverse
reactions with proper supplementation.
Drug Interactions:
Consult a physician before taking NutraLibido, as the
following key nutrients may interact with certain
medications.
Avena Sativa: Statins (oat bran may impair absorption)
Cocoa: There are no known interactions with proper
supplementation.
Dong Quai: Blood Thinning Medicine (Coumadin,
Plavix, etc.) Antithrombolytics
Gingko Biloba: Blood thinning medicine (Coumadin,
Plavix, etc.); Pain Relievers (Advil, Motrin, etc.),
Naproxen (Aleve, etc.); Anti-Depressants (Zoloft, Paxil,
etc.); High blood pressure medicine (Cardizem, Cardene,
etc.); Anti-convulsants (Dilantin, Tegretol, etc.); and/or
Insulin.
Ginseng: Albendazole, Anticoagulants, Insulin, Estrogen,
MAOIs, Nifedipine
L-Arginine: Diuretics (Aldactone, Midamor, Dyazide,
etc.); Estrogen (Premarin, Estrace, etc.); Ibuprofen;
Sildenafil Citrate; Cyclosporine; Organic Nitrates
Maca Root: There are no known interactions with proper
supplementation.
Muira Puama: There are no known interactions with
proper supplementation.
Tribulus Terrestris: There are no known interactions
with proper supplementation.
Store in a cool, dry place, away from direct light. Keep
out of reach of children.
1. Abascal K, Yarnell E. Nervine Herbs for Treating Anxiety. Alternative
and Complementary Therapies. 2004; 10(6):309-315.
2. Duke JA. Biological Activity Summary for Cocao (Theobroma cacao
L.). Journal of Medicinal Food. 2000; 3(2):115-119.
3. Heiss C, Kleinbongard P, Dejam A, et al. Acute consumption of
flavanol-rich cocoa and the reversal of endothelial dysfunction in
smokers. J Am Coll Cardiol. 2005; 46(7):1276-1283.
4. Heiss C, Dejam A, Kleinbongard P, et al. Vascular effects of cocoa
rich in flavan-3-ols. JAMA. 2003; 290(8):1030-1031.
5. Zhu D. Dong Quai. Amer J Chin Med. 1987; 15(3-4):117-125.
6. Wu YZ, Li SQ, Zu XG, Du J, Wang FF. Ginkgo biloba extract
improves coronary artery circulation in patients with coronary artery
disease: contribution of plasma nitric oxide and endothelin-1. Phytother
Res. 2008; 22(6):734-739.
7. Sikora R, et al. Ginkgo biloba extract in the therapy of erectile
dysfunction. J Urol. 1989; 141:188A.
8. Yoshikawa T, Naito Y, Kondo M. Ginkgo biloba leaf extract: review of
biological actions and clinical applications. Antioxidants & Redox
Signaling. 1999; 1(4):469-480.
9. Wu Y, Li S, Cui W, Zu X, Du J, Wang F. Ginkgo biloba extract
improves coronary blood flow in healthy elderly adults: role of
endothelium-dependent vasodilation. Phytomedicine. 2008; 15(3):164169.
10. Murphy LL, Lee TJ. Ginseng, sex behavior, and nitric oxide. Ann NY
Acad Sci. 2002; 962:372-377.
11. Sandroni P. Aphrodisiacs past and present: a historical review. Clin
Auton Res. 2001; 11(5): 303-307.
12. Ito TY, Polan ML, Whipple B, Trant AS. The enhancement of female
sexual function with ArginMax, a nutritional supplement, among women
differing in menopausal status. Sex Marital Ther. 2006; 32(5):369-378.
13. Kim SO, Kim MK, Lee HS, Park JK, Park K. The Effect of Korean
Red Ginseng Extract on the Relaxation Response in Isolated Rabbit
Vaginal Tissue and Its Mechanism. J Sex Med. 2008 Jul 14.
14. Kim C, Choi H, Kim CC, Kim JK, Kim MS. Influence of ginseng on
mating behavior of male rats. Am J Chin Med. 1976; 4(2):163-168.
15. Simonsen U, Prieto D, Delgado JA, Hernandez M, et al. Nitric oxide
is involved in the inhibitory neurotransmission and endotheliumdependent relaxations of human small penile arteries. Clin Sci. 1997;
92(3):269-275.
16. Chen J, Wollman Y, Chernichovsky T, Iaina A, Sofer M, Matzkin H.
Effect of oral administration of high-dose nitric oxide donor L-Arginine
in men with organic erectile dysfunction: results of a double-blind,
randomized, placebo-controlled study. BJU Int. 1999; 83(3):269-273.
17. Moody JA, Vernet D, Laidlaw S, Rajfer J, Gonzalez-Cadavid NF.
Effects of long-term oral administration of L-Arginine on the rat erectile
response. J Urol. 1997; 158(3): 942-947.
18. Stanislavov R, Nikolova V, Rohdewald P. Improvement of erectile
function with Prelox: a randomized, double-blind, placebo-controlled,
crossover trial. Int J Impot Res. 2008; 20(2): 173-180.
19. Lebret T, Herve JM, Gorny P, Worcel M, Botto H. Efficacy and
safety of a novel combination of L-Arginine glutamate and yohimbine
hydrochloride: a new oral therapy for erectile dysfunction. Eur Urol.
2002; 41(6):608-613.
20. Gonzales GF, Cordova A, Vega K, Chung A, et al. Effect of
Lepidium meyenii (MACA) on sexual desire and its absent relationship
with serum testosterone levels in adult healthy men. Andologia. 2002;
34(6):598-602.
21. Zheng BL, He K, Kim CH, Rogers L, et al. Effect of a lipidic extract
from lepidium meyenii on sexual behavior in mice and rats. Urology.
2000; 55(4):598-602.
22. Ruiz-Luna AC, Salazar S, Aspajo NJ, Rubio J, et al. Lepidium
meyenii (Maca) increases litter size in normal adult female mice. Reprod
Biol Endocrinol. 2005; 3:16.
23. Lentz A, Gravitt K, Carson CC, Marson L. Acute and chronic dosing
of Lepidium meyenii (Maca) on male rat sexual behavior. J Sex Med.
2007; 4(2):332-339.
24. Gonzales GF, Nieto J, Rubio J, Gasco M. Effect of Black maca
(Lepidium meyenii) on one spermatogenic cycle in rats. Andrologia.
2006; 38(5):166-172.
25. Waynberg J, Brewer S. Effects of Herbal vX on libido and sexual
activity in premenopausal and postmenopausal women. Adv Ther. 2000;
17(5):255-262.
26. Da Silva AL, Bardini S, Nunes, DS, Elisabetsky, E. Anxiogenic
properties of Ptychopetalum olacoides Benth. (Marapuama). Phytotherapy
Research. 2002; 16(3):223-226.
27. Gauthaman K, Ganesan AP. The hormonal effects of Tribulus
terrestris and its role in the management of male erectile dysfunction--an
evaluation using primates, rabbit and rat. Phytomedicine. 2008; 15(12):44-54.
28. Gauthaman K, Adaikan PG, Prasad RN. Aphrodisiac properties of
Tribulus Terrestris extract (Protodioscin) in normal and castrated rats.
Life Sci. 2002; 71(12):1385-1396.
29. Gauthaman K, Adaikan PG. Effect of Tribulus terrestris on
nicotinamide adenine dinucleotide phosphate-diaphorase activity and
androgen receptors in rat brain. J Ethnopharmacol. 2005; 96(1-2):127132.
30. Adaikan PG, Gauthaman K, Prasad RN, Ng SC. Proerectile
pharmacological effects of Tribulus terrestris extract on the rabbit corpus
cavernosum. Ann Acad Med Singapore. 2000; 29(1):22-26.
These statements have not been evaluated by the
Food and Drug Administration. This product is not
intended to diagnose, treat, cure, or prevent any disease.
Manufactured for:
PCCA
9901 S. Wilcrest Dr.
Houston, TX 77099
281.933.6948

Omega 780 EC contains pharmaceutical grade, entericcoated, ultra-pure fish oils. These molecularly distilled
oils provide 780 milligrams of omega-3 essentials fatty
acids per softgel. To ensure purity, every batch is assayed
for heavy-metal contamination.
At the same time as the media increases consumer
awareness of the importance of fish oils, manufacturers
face the challenge of eliminating heavy metals and PCBs.
The industry-leading technologies used in the preparation
of Omega 780 EC surpass all national and international
standards for environmental pollutants, including dioxins,
PCBs, pesticides, and heavy metals, including mercury.
Wellness Works’ Omega 780 EC oils are processed
through special molecular distillation. Molecular
distillation is commonly used to purify and concentrate
fish oils. In this process, the fish oil is broken down into
its basic molecular components and separated by
molecular weight. Due to varying molecular weights,
specific components can be removed or concentrated to
the oil. This ensures that contaminants can be reduced to
levels far below industry standards. It also allows the
manufacturer to increase the concentration of active
ingredients.
Processing this fish oil formula begins with rigorous care
and control of the starting raw materials (non-GMO
sardines, mackerel, anchovies) to assure optimum oil
quality. The oils are distilled in a controlled, pristine
vacuum environment to minimize distillation
temperatures. The exposure time, even to these lower
distillation temperatures, is tightly controlled and uniform,
resulting in levels of impurities well below the industry
standards.
The technology employed for the Omega 780 EC meets
special molecular distillation standards. As this oil is a
concentrated source of omega-3 fatty acids, our
manufacturer goes above and beyond the traditional
purification methods to ensure its safety. This is
accomplished by:


A triple-phase molecular distillation purification
process to maximize purity while concentrating
the EPA and DHA polyunsaturated fatty acids
Ensuring consistency in contaminant removal,
and therefore purity levels, through uniform
processing times
Reducing the evaporation stage to half the time
of traditional systems to drive down the oxidative
risk
The proprietary technologies used in the manufacture of
Omega 780 EC oils are in accordance with pharmaceutical
standards that assure safe, consistent fish oils that exceed
Council for Responsible Nutrition (CRN) Monograph
standards and meet all international standards for oil
safety, including WHO, Prop 65, and more.[9]
Despite aggressive marketing claims to the contrary, a
recent publication by Oelrich et al reported that of the
three formulations tested, there was no significant
difference in the effect on triglycerides.[10] The active
therapy of the three fish oil supplementation arms was 4
g/day of combined EPA and DHA provided as: a) 90%
triglyceride (TG) formulation (TG90), b) 60% TG
formulation (TG60), or c) ethyl esters (EE) (i.e., 0% TG).
Furthermore, omega-3 fish oils provided in an ethyl ester
formulation tended to have a lower impact on increasing
LDL-cholesterol levels compared to omega-3 fish oils
delivered in the triglyceride formulation.
It takes 2 gm/day of DHA supplementation for a month to
saturate the plasma and three to six months of
supplementation to saturate the tissues. Concentrations
increase in breast milk within less than a week of DHA
supplementation. Research suggests that omega-3 fatty
acids are beneficial in supporting balanced cytokine
production and neurological health. Furthermore,
supportive but not conclusive research shows that
consumption of EPA and DHA omega-3 fatty acids may
reduce the risk of coronary heart disease.
Omega 780 EC softgels may be a useful dietary
supplement for those who wish to supplement with fish
oils.
Vitamin E (as mixed tocopherols) ....................10 I.U.
Fish Oil Concentrate ............................................ 1.4 g
EPA (eicosapentaenoic acid) .................. 450 mg
DHA (docosahexaenoic acid) ................. 330 mg
Other Ingredients: Gelatin, glycerin, purified water,
enteric coating, and natural lemon oil.
Contains: Fish (anchovy and sardine).
As a dietary supplement, adults take one or two softgels
one to three times daily, or as directed by a healthcare
professional.
No adverse effects have been reported.
Store in a cool, dry place, away from direct light. Keep
out of reach of children.
1. Calder PC. n-3 Fatty acids and cardiovascular disease: evidence
explained and mechanisms expored. Clin Sci (Lond). 2004 Jul;107(1):111 [PMID: 15132735]
2. Storey A, McArdle F, Friendmann PS, Jackson MJ, Rhodes LE.
Eicosapentaenoic acid and docosahexaenoic acid reduce UVB- and TNF
alpha-induced IL-8 secretion in keratinocytes and UVB-induced IL-8 in
fibrolasts. J Invest Dermatol. 2005 Jan;124(1):248-55. [PMID:
15654981]
3. Ki YJ, Kim HJ, No JK, Chung HY, Fernandes G. Anti-inflammatory
action of dietary fish oil and calorie restriction. Life Sci 2006 Apr
18;78(21): 2523-32. Epub 2006 Jan 24 [PMID: 16438990]
4. Maroon JC, Bost JW. Omega-3 Fatty acids (fish oil) as an antiinflammatory: an alternative to nonsteroidal anti-inflammatory drugs for
discogenic pain. Surg Neurol.2006 Apr; 65 (4):326-31 [PMID:
16531187]
5. Frangou S, Lewis M, McCrone P. Efficacy of ethyl-eicosapentaenoic
acid in bipolar depression: randomized double-blind placebo-controlled
study. Br J Psychiatry. 2006 Jan;188:46-50. [PMID: 16388069]
6. Kankaanpaa P, Sutas Y, Salminen S, Lichtenstein A, Isolauri E.
Dietary fatty acids and allergy. Ann Med. 1999 Aug;31(4):282-7. [PMID:
10480759]
7. Ebbesson SO, Risica PM, Ebbesson LO, Kennish JM, TejeroME.
Omega-3 fatty acids improve glucose tolerance and components of the
metabolic syndrome in Alaskan Eskimos: the Alaska Siberia project. Int J
Circumpolar Health. 2005 Sep:64(4):396-408. [PMID:16277123]
8. Nettleton JA, Katz R. n-3 long-chain polyunsaturated fatty acids in type
2 diabetes: a review. J Am Diet Assoc. 2005 Mar;105(3):428-40
[PMID:15746832]
9. Molecular Distillation Reference Sheet. Bioriginal Food and Science
Corp. Saskatchewan, CA
10. Oelrich B, Dewell A, Gardner CD. Effect of fish oil supplementation
on serum triglycerides, LDL cholesterol and LDL subfractions in
hypertriglyceridemic adults. Nutr Metab Cardiovasc Dis. 2011 Sep 15.
Epub ahead of print. [PMID: 21924882]
These statements have not been evaluated by the
Food and Drug Administration. This product is not
intended to diagnose, treat, cure, or prevent any disease.
Manufactured for:
PCCA
9901 S. Wilcrest Dr.
Houston, TX 77099
281.933.6948
Omega Fusion Lemon is a delicious alternative for those
who can’t tolerate the taste of fish oil or have difficulty
digesting fats. As an emulsified form of fish oil with a
“lemon meringue” flavor, Omega Lemon Fusion ensures
higher compliance and optimal intake of the essential fatty
acids.
Fish Oil is an excellent source of the omega-3 essential
fatty acids Eicosapentaenoic acid (EPA) and
Docosahexaenoic acid (DHA). Omega-3 fatty acids have
been shown to support cardiovascular and neurological
health, as well as healthy vision. Studies show that omega3 fats EPA and DHA help support normal, healthy blood
cholesterol and triglyceride levels and a healthy, normal
inflammatory response. Since the body is only capable of
producing limited amounts of EPA and DHA from the
essential omega-3 fatty acid alpha-linolenic acid (ALA),
we must, therefore consume them through our diet or
supplementation. Since many consumers either dislike the
taste of fish oil or aren’t amenable to taking large fish oil
capsules, Omega Lemon Fusion is a pleasant tasting,
highly bio-available form of Omega-3 fatty acids without
the fish oil taste or cumbersome capsules. The delicious
taste encourages daily compliance, and ensures optimal
intake of the omega-3 fats. Each serving (2 teaspoons)
provides 360 mg of EPA and 360 mg of DHA and there is
evidence to suggest that emulsified forms of fish oil
provide up to 90% greater absorption than standard fish
oils.
Manufactured using the highest quality molecularly
distilled fish oil; Omega 3 Fusion meets the strictest
standards for mercury, lead, PCBs and other toxins that
are found in many other fish oils. Consuming fish oil in a
flavored, emulsified form is a safe and effective way to
ensure an optimal intake of EPA and DHA each day.
As a dietary supplement, Omega Fusion Lemon provides a
blend of the essential fatty acids that play an important
role in supporting cardiovascular and neurological health,
as well as healthy vision and inflammation.
Eicosapentaenoic Acids (EPA) ........................... 360 mg
Docosahexaenoic Acids (DHA) .......................... 360 mg
Other Omega 3 Acids ......................................... 280 mg
Linoleic Acid (Omega 6) .................................... 100 mg
Other Omega 6 Acids ......................................... 100 mg
Oleic Acid (Omega 9) ......................................... 690 mg
Other Omega 9 Acids ......................................... 140 mg
Other Ingredients: Pure fish oil (salmon and/or cod liver
oil), water, xylitol, glycerine, gum arabic, natural flavors,
citric acid, xanthan gum, guar gum, sorbic acid, turmeric,
Vitamin E, and ascorbyl palmitate.
As a dietary supplement, adults and children (4 years and
older) take two (2) teaspoons daily, or as directed by a
health care professional. Shake well prior to use.
Please consult with a healthcare professional before taking
Omega Fusion Lemon if you are taking medications that
thin the blood. Discontinue use of Omega Fusion Lemon
if you are anticipating a surgical procedure.
Keep out of reach of children. Keep refrigerated after
opening.
Holman RT (February 1998). "The slow discovery of the importance of
omega 3 essential fatty acids in human health". J. Nutr. 128 (2 Suppl):
427S–433S.
Ho L, van Leeuwen R, Witteman JC, van Duijn CM, Uitterlinden AG,
Hofman A, de Jong PT, Vingerling JR, Klaver CC. Reducing the genetic
risk of age-related macular degeneration with dietary antioxidants, zinc,
and ω-3 fatty acids: the Rotterdam study. Arch Ophthalmol. 2011
Jun;129(6):758-66.
Wall R, Ross RP, Fitzgerald GF, Stanton C (2010). "Fatty acids from
fish: the anti-inflammatory potential of long-chain omega-3 fatty acids".
Nutr Rev 68 (5): 280–9
Wang, C; Harris, WS; Chung, M; Lichtenstein, AH; Balk, EM;
Kupelnick, B; Jordan, HS; Lau, J (2006 Jul). "n-3 Fatty acids from fish or
fish-oil supplements, but not alpha-linolenic acid, benefit cardiovascular
disease outcomes in primary- and secondary-prevention studies: a
systematic review.". The American journal of clinical nutrition 84 (1): 517.
Perica, MM; Delas, I (2011 Aug). "Essential fatty acids and psychiatric
disorders.". Nutrition in clinical practice : official publication of the
American Society for Parenteral and Enteral Nutrition 26 (4): 409-25.
Naliwaiko, K.; Araújo, R.L.; da Fonseca, R.V.; Castilho, J.C.; Andreatini,
R.; Bellissimo, M.I.; Oliveira, B.H.; Martins, E.F.; Curi, R.; Fernandes,
L.C.; Ferraz, A.C. (April 2004). "Effects of fish oil on the central nervous
system: a new potential antidepressant?". Nutritional Neuroscience
(Maney) 7 (2): 91–99.
Goldberg RJ, Katz J. A meta-analysis of the analgesic effects of omega-3
polyunsaturated fatty acid supplementation for inflammatory joint pain.
Pain. 2007 Feb 28
Dr. Tom Gilhooly. Improved Bioavailability of Omega 3 from a Fish Oil
Emulsion in Comparison to Standard Omega 3 Fish Oil, The Essential
Health Clinic; Glasgow, Scotland.
These statements have not been evaluated by the
Food and Drug Administration. This product is not
intended to diagnose, treat, cure, or prevent any disease.
Manufactured for:
PCCA
9901 S. Wilcrest Dr.
Houston, TX 77099
281.933.6948
oxidation at the expense of cholesterol formation.
Pantethine offers 500 mg Pantethine in tablet form.
Pantethine is the biologically active form of Pantothenic
acid (vitamin B5), a proven treatment in dyslipidemia
(disorders of blood lipids, including high cholesterol).
Cholesterol is a blood lipid, a fatty substance that is found
in all parts of the body. When the concentration of
cholesterol in the blood is too high, many problems,
including heart disease, can occur. While cholesterol is
manufactured within the body, the average “American
diet” provides an excessive intake of cholesterol and fat,
leading to many serious health problems.
An effective supplement that has proven to help reduce
low density lipoproteins (LDL – the “bad cholesterol”)
while simultaneously raising high density lipoproteins
(HDL—the “good” cholesterol) is pantethine. In study
after study, this beneficial supplement has proven to help
patients control their cholesterol levels.
A number of studies focused on a group of people with
particular health concerns (i.e. diabetics, peri-menopausal,
etc.) and in each conclusion, pantethine worked in these
health conditions without any detrimental side effects.
The metabolic activity of pantethine is probably due to its
role in the synthesis of CoA and acyl carrier proteins.
CoA is a cofactor in over 70 enzymatic pathways
including fatty acid oxidation, carbohydrate metabolism,
pyruvate degradation, amino acid catabolism, heme
synthesis, acetylcholine synthesis, and phase II
detoxification acetylation. ACP is an essential component
of the fatty acid synthase complex required for fatty acid
elongation.
While the exact mechanism of action of pantethine in
normalizing parameters associated with dyslipidemia is
unknown, several explanations have been proposed. Some
authors have suggested pantethine might be capable of
directly modulating the action of several enzymes
involved in cholesterol synthesis.
The efficacy of pantethine in normalizing parameters of
dyslipidemia might also be due to its ability to increase
CoA levels. Theoretically, if pantethine enhances the
formation of CoA, the additional CoA might then combine
with free acetyl groups to form acetyl-CoA. The acetylCoA could then be directed into the TCA cycle or betaThese statements have not been evaluated by the
Food and Drug Administration. This product is not
intended to diagnose, treat, cure, or prevent any disease.
In addition to its cholesterol lowering abilities, several
human and animal studies have concluded that pantethine
may support other functions, including the healthy
metabolism of blood glucose, as well as adrenal and eye
health.
Pantethine tablets may be a useful dietary supplement for
individuals who wish to support their cardiovascular
system and help maintain healthy cholesterol levels.
Pantethine .......................................................... 500 mg
Adults take 1 tablet daily with meals or as directed
by physician.
No adverse effects have been reported.
Store in a cool, dry place, away from direct light.
Keep out of reach of children.
Binaghi P, Cellina G, Lo Cicero G, et al. Evaluation of the cholesterollowering effectiveness of pantethine in women in perimenopausal age.
Minerva Med 1990;81:475-479.
Coronel F, Tornero F, Torrente J, Naranjo P, De Oleo P, Macia M,
Barrientos A. Treatment of hyperlipemia in diabetic patients on dialysis
with a physiological substance. Am J Nephrol 1991;11(1):32-6.
Donati C, Bertieri RS, Barbi G. Pantethine, diabetes mellitus and
atherosclerosis. Clinical study of 1045 patients. Clin Ter 1989 Mar
31;128(6):411-22.
Gensini GF, Prisco D, Rogasi PG, et al. Changes in fatty acid
composition of the single platelet phospholipids induced by pantethine
treatment. Int J Clin Pharmacol Res 1985;5:309-318.
Hiramatsu K, Nozaki H, Arimori S. Influence of pantethine on platelet
volume, microviscosity, lipid composition and functions in diabetes
mellitus with hyperlipidemia. Tokai J Exp Clin Med 1981;6:49-57.
Murai A, Miyahara T, Tanaka T, et al. The effects of pantethine on lipid
and lipoprotein abnormalities in survivors of cerebral infarction. Artery
1985;12:234-243.
Nomura H, Kimura Y, Okamoto O, Shiraishi G. Effects of
antihyperlipidemic drugs and diet plus exercise therapy in the treatment
of patients with moderate hypercholesterolemia. Clin Ther 1996 MayJun;18(3):477-82
Osono Y, Hirose N, Nakajima K, Hata Y. The effects of pantethine on
fatty liver and fat distribution. J Atheroscler Thromb 2000;7(1):55-8.
Prisco D, Rogasi PG, Matucci M, et al. Effect of oral treatment with
pantethine on platelet and plasma phospholipids in IIa
hyperlipoproteinemia. Angiology 1987;38:241-247.
Manufactured for:
PCCA
9901 S. Wilcrest Dr.
Houston, TX 77099
281.933.6948
Perfect E features the complete family of vitamin E
compounds. Until recently, most vitamin E supplements
only contained alpha-tocopherol – one of the most active
forms of vitamin E. But research has demonstrated the
importance of consuming the entire family of vitamin E
compounds.
Vitamin E is a collective name for a group of eight
different compounds; alpha, beta, gamma and deltatocopherol and alpha, beta, gamma and delta-tocotrienol.
Until recently, research on vitamin E has focused on
alpha-tocopherol but research shows that taking several
different isomers of this vitamin is better than taking any
singularly. In addition, high intakes of alpha-tocopherol
can decrease tocotrienols in the body; hence the
importance of taking both forms. Although alphatocopherol is well known as an antioxidant, tocotrienols
have additional biochemical and physiological effects that
benefit the body. As an example, unlike alpha-tocopherol,
gamma-tocopherol has the ability to protect against
nitrogen-based free radicals. This type of free radical
plays an important role in diseases associated with chronic
inflammation. Tocotrienols have been shown to support
normal, healthy cholesterol level through its effect on
HMG-CoA reductase enzyme. They have also been shown
to support, normal blood clotting and normal, healthy cell
growth.
Vitamin E is an important nutrient derived from the diet.
Perfect E provides a complete blend of vitamin E
compounds that may be lacking in the diet or for those
who wish to support normal, healthy cardiovascular
health.
Vitamin E ....................................... ……………..400 IU
(as d-alpha tocopherol)
Mixed Tocopherols ............................................ .536 mg
d-gamma tocopherol ........................................ 400 mg
d-delta tocopherol .............................................. 91 mg
d-beta tocopherol ............................................... 45 mg
Tocotrienols (from palm) ...................................... 40 mg
Gamma tocotrienol ............................................ 21 mg
Delta tocotrienol .................................................. 8 mg
Alpha tocotrienol ............................................... 12 mg
Beta tocotrienol ................................................... 1 mg
Adults take one (1) softgel capsule daily with meals or as
directed by a healthcare professional
Vitamin E might slow blood clotting. Please consult with
a healthcare professional before taking Perfect E if you
are on certain medications changed by the liver
(Cytochrome P450 3A4 (CYP3A4) substrates),
anticoagulants or medication to lower cholesterol.
Because vitamin E is an antioxidant it may interact with
anticancer medication.
Store in a cool, dry place, away from direct light. Keep
out of reach of children.
Contains no sugar, salt, dairy, yeast, wheat, gluten, corn,
preservatives, artificial colors or flavors.
Cerecetto H, López GV (March 2007). "Antioxidants derived from
vitamin E: an overview". Mini Reviews in Medicinal Chemistry 7 (3):
315–38.
Jiang Q, Christen S, Shigenaga MK, Ames BN. gamma-tocopherol, the
major form of vitamin E in the US diet, deserves more attention. Am J
Clin Nutr. 2001 Dec;74(6):714-22.
Ikeda S, Tohyama T, Yoshimura H, Hamamura K, Abe K, Yamashita K
(February 2003). "Dietary alpha-tocopherol decreases alpha-tocotrienol
but not gamma-tocotrienol concentration in rats". J. Nutr. 133 (2): 428–
34.
Christen S, Woodall AA, Shigenaga MK, Southwell-Keely PT, Duncan
MW, Ames BN. gamma-tocopherol traps mutagenic electrophiles such as
NO(X) and complements alpha-tocopherol: physiological implications.
Proc Natl Acad Sci U S A. 1997 Apr 1;94(7):3217-22.
Qureshi AA, Pearce BC, Nor RM, Gapor A, Peterson DM, Elson CE
(February 1996). "Dietary alpha-tocopherol attenuates the impact of
gamma-tocotrienol on hepatic 3-hydroxy-3-methylglutaryl coenzyme A
reductase activity in chickens". The Journal of Nutrition 126 (2): 389–94.
Shu-Ping Lee, Guang-Yuan Mar and Lean-Teik Ng (2009). Effects of
tocotrienol-rich fraction on exercise endurance capacity and oxidative
stress in forced swimming rats. European Journal of Applied Physiology
(Epub ahead of print) DOI 10.1007/s00421-009-1159-6.
Maniam S, Mohamed N, Shuid AN, Soelaiman IN (2008). Palm
tocotrienol exerted better antioxidant activities in bone than alphatocopherol. Basic & Clinical Pharmacology & Toxicology, 103, 55-60.
Ajuluchukwu JN, Okubadejo NU, Mabayoje M, Ojini FI, Okwudiafor
RN, Mbakwem AC, Fasanmade OA, Oke DA. (2007) Comparative study
of the effect of tocotrienols and -tocopherol on fasting serum lipid profiles
in patients with mild hypercholesterolaemia: a preliminary report.
Nigerian Postgraduate Medical Journal 14(1):30-3.
Minhajuddin M, Beg ZH, Iqbal J (2005) Hypolipidemic and antioxidant
properties of tocotrienol rich fraction isolated from rice bran oil in
experimentally induced hyperlipidemic rats. Food and Chemical
Toxicolology 43(5):747-53.
Baliarsingh S, Beg ZH, Ahmad J. (2005) The therapeutic impacts of
tocotrienols in type 2 diabetic patients with hyperlipidemia.
Atherosclerosis 182(2):367-74.
Rasool AH, Rahman AR, Yuen KH, Wong AR (2008). Arterial
compliance and vitamin E blood levels with a self emulsifying
preparation of tocotrienol rich vitamin E. Arch Pharm Res. 31(9):1212-7.
Das M, Das S, Wang P, Powell SR, Das DK (2008). Caveolin and
proteasome in tocotrienol mediated myocardial protection. Cell Physiol
Biochem 2008: 22:287-294.
Das S, Lekli I, Das M, Szanp G, Varado
J, Juhasz B, Bak I, Nesaretnam K, Tosaki A, Powell SR, Das DK. (2008)
Cardioprotection with palm oil tocotrienols: comparision of different
isomers. Am J Physiol Heart Circ Physiol 294: H970-H978
These statements have not been evaluated by the
Food and Drug Administration. This product is not
intended to diagnose, treat, cure, or prevent any disease.
Manufactured for:
PCCA
9901 S. Wilcrest Dr.
Houston, TX 77099
281.933.6948
Pyridoxal-5-Phosphate provides 50 mg of Pyridoxal-5Phosphate per each capsule.
Pyridoxal-5-Phosphate (P5P) is the metabolically active
coenzyme of Vitamin B6. The body must convert B6
vitamins to pyridoxal, and then phosphorylate them to
P5P in the liver. This conversion is necessary, since P5P
is the only form which can be used by the enzymes
involved in biochemical processes, which are associated
with nitrogen and protein metabolism and heme synthesis.
P5P is exported from the liver and is considered the most
relevant direct measure of vitamin B6 status. Vitamin B6
nutritional status can have a significant and selective
modulatory impact on central production of both serotonin
and GABA ¬ neurotransmitters, which can positively
affect emotional response, pain perception, and anxiety.
Vitamin B6 has also been studied for cardiovascular uses
as well.
Bender D. Non-nutritional uses of vitamin B6. Br J Nutr 1999;81:7-20.
Fuhr JE, Farrow A, Nelson HS Jr. Vitamin B6 levels in patients with
carpal tunnel syndrome. Arch Surg 1989;124:1329-1330.
Head KA. Premenstrual syndrome: nutritional and alternative approaches.
Altern Med Rev 1997;2:12-25.
Leklem JE. Vitamin B6:a status report. J Nutr 1990;120:1503-1507
McCarty MF. High-dose pyridoxine as an ‘anti-stress' strategy. Med
Hypotheses 2000;54:803-807.
Merrill AH Jr, Henderson JM. Vitamin B6 metabolism by human liver.
Ann N Y Acad Sci 1990;585:110-117.
Oka T. Vitamin B6. Nippon Rinsho 1999;57:2199-2204. [Article in
Japanese].
Rimm EB, Willett WC, Hu FB, et al. Folate and vitamin B6 from diet and
supplements in relation to risk of coronary heart disease among women.
JAMA 1998;279:359-364.
Pyridoxal-5-Phosphate may be a useful dietary
supplement for individuals wishing to increase their intake
of a metabolically active form of Vitamin B6.
Pyridoxal-5-Phosphate .......................................... 50 mg
Adults take 1 capsule daily with meals or as directed by
physician.
No adverse effects have been reported.
Store in a cool, dry place, away from direct light.
Keep out of reach of children.
These statements have not been evaluated by the
Food and Drug Administration. This product is not
intended to diagnose, treat, cure, or prevent any disease.
Manufactured for:
PCCA
9901 S. Wilcrest Dr.
Houston, TX 77099
281.933.6948
Red yeast rice is a traditional Asian food that dates back
to 800 AD. Scientific studies have shown that red yeast
rice can help to support healthy cholesterol levels that are
already within the normal range. It is organically grown in
the USA and is free of citrinin, a toxin that can be found
in fermented foods. CoQ10, milk thistle and n-acetylcysteine are included for added liver support.
Cardiovascular disease continues to be the leading cause
of mortality in the United States. One of the major risk
factors for cardiovascular disease is elevated total and
LDL (“bad”) cholesterol. There are several categories of
prescription drugs that are designed to help lower
cholesterol; the most commonly prescribed being the
Statin drugs. Statins are effective at lowering total and
LDL cholesterol, but they are associated with significant
side effects. Many individuals with elevated cholesterol
have been able to improve their cardiovascular health
through diet, exercise and nutraceutical supplements.
One of the nutraceuticals that has been shown in research
studies to support normal LDL and total cholesterol levels
is red yeast rice. Red yeast rice is the product of yeast
(Monascus purpureus) grown on rice and it contains
several compounds collectively known as monacolins that
work similar to statin drugs and support the mechanisms
that can lead to improved cardiovascular health. Taking
red yeast rice for extended periods of time could affect
CoQ10 levels because the mechanism of action of red
yeast rice and statin medications are similar. It is also
important to support healthy liver function when taking
red yeast rice or statin medication. Therefore, Red Yeast
Rice Plus is combined with CoQ10 as well as compounds
like N-acetyl-cysteine (NAC) and standardized milk
thistle. N-acetyl-cysteine plays a critical role in
regenerating glutathione, an important antioxidant and
detoxing compound found in the liver. Milk thistle has
been shown to protect hepatic cells and support healthy
liver function and detoxification.
In conjunction with a healthy diet and exercise, Red Yeast
Rice Plus may be a useful dietary supplement for those
who wish to support healthy cholesterol levels.
Organic Red Yeast Rice (Monascus purpureus) . 600 mg
N-acetyl-cysteine .................................................. 50 mg
Milk Thistle .......................................................... 25 mg
(Silybum marianum 80% [20 mg] silymarin)
Coenzyme Q10 (as ubiquinone) ........................... 30 mg
Other Ingredients: Vegetarian capsule (cellulose, water),
cellulose, stearic acid, magnesium stearate and silica.
As a dietary supplement, adults take one (1) capsule,
twice (2) daily with meals or as directed by a healthcare
professional.
Do not use this product if you are pregnant, lactating or
have liver disease. Individuals who take prescription
medication to lower their cholesterol should consult with
their healthcare professional before using.
Store in a cool, dry place, away from direct light. Keep
out of reach of children.
Cicero AF, Rovati LC, Setnikar I. Eulipidemic effects of berberine
administered alone or in combination with other natural cholesterollowering agents. A single-blind clinical investigation.
Arzneimittelforschung 2007;57(1):26-30.
Heber D, Lembertas A, Lu QY, et al. An analysis of nine proprietary
Chinese red yeast rice dietary supplements: implications of variability in
chemical profile and contents. J Altern Complement Med 2001;7(2):133139.
Huang CF, Li TC, Lin CC, et al. Efficacy of Monascus purpureus Went
rice on lowering lipid ratios in hypercholesterolemic patients. Eur J
Cardiovasc Prev Rehabil 2007 Jun;14(3):438-40.
Li JJ, Hu SS, Fang CH, et al. Effects of xuezhikang, an extract of
cholestin, on lipid profile and C-reactive protein: a short-term time course
study in patients with stable angina. Clin Chim Acta 2005;352(1-2):217224.
Liu BH, Wu TS, Su MC, et al. Evaluation of citrinin occurrence and
cytotoxicity in Monascus fermentation products. J Agric Food Chem
2005;53(1):170-175.
Liu L, Zhao SP, Cheng YC, et al. Xuezhikang decreases serum
lipoprotein(a) and C-reactive protein concentrations in patients with
coronary heart disease. Clin Chem 2003;49(8):1347-1352.
Man RY, Lynn EG, Cheung F, et al. Cholestin inhibits cholesterol
synthesis and secretion in hepatic cells (HepG2). Mol Cell Biochem
2002;233(1-2):153-158.
Yang HT, Lin SH, Huang SY, et al. Acute administration of red yeast rice
(Monascus purpureus) depletes tissue coenzyme Q(10) levels in ICR
mice. Br J Nutr 2005;93(1):131-135.
Zuber R, Modriansky M, Dvorak Z, et al. Effect of silybin and its
congeners on human liver microsomal cytochrome P450 activities.
Phytother Res 2002;16(7):632-638.
Tamayo C, Diamond S. (2007). Review of clinical trials evaluating safety
and efficacy of milk thistle (Silybum marianum [L.] Gaertn.). Integrative
Cancer Therapies. 6: 146-157.
Gross, Clark L.; Innace, Joy K.; Hovatter, Renee C.; Meier, Henry L.;
Smith, William J. (1993). "Biochemical manipulation of intracellular
glutathione levels influences cytotoxicity to isolated human lymphocytes
by sulfur mustard". Cell Biology and Toxicology 9 (3): 259–67.
These statements have not been evaluated by the
Food and Drug Administration. This product is not
intended to diagnose, treat, cure, or prevent any disease.
Manufactured for:
PCCA
9901 S. Wilcrest Dr.
Houston, TX 77099
281.933.6948
Maintain energy and manage stress. Rhodiola Rosea is an
adaptogen that can benefit physical, biological, and
chemical stressors in the body. Its properties may help
stimulate the nervous system, balance mood, reduce
fatigue, and sustain cognitive function. Rhodiola Rosea
can help you get through the day with increased
endurance, energy, and well-being.
Mood Balance: Rhodiola’s adaptogenic properties can
improve mood imbalances. A six-week study recruited
individuals with mood ailments to take rhodiola extract,
finding mood, sleep, and emotions improved in subjects
taking rhodiola extract.12 Similarly, rhodiola may alleviate
chronic anxiety, as a ten-week study demonstrated it
significantly reduced anxiety among individuals taking the
extract.13
Adrenal Health: Rhodiola extracts can help maintain
proper function of the hypothalamic-pituitary-adrenal axis
and relieve mental stress.1,2 The extract can prevent
behavioral and physiological changes that are often
associated with chronic stress, as well as stimulate the
central nervous system to balance mood and behavior.3
Rhodiola Rosea, also known as Artic or Golden root, is a
plant that originates in Siberia and Northwestern China. It
contains adaptogen properties, such as rosavins and other
constituents, to increase the body’s resistance to stress and
mental fatigue.
Cardiovascular Health: Stress-induced damage to
cardiovascular tissue can be moderated by rhodiola rosea. 4
The extract has been shown to decrease adrenalineinduced arrhythmias that can injure cardiovascular tissue.5
Rhodiola has been shown to inhibit plaque formation and
improve endothelial function.6
Rhodiola Rosea ................................................... 100 mg
(2% Rosavins, 1% Salidrosides)
Cognitive Function: Rhodiola can support cognitive
abilities. Forty females who experienced stressful
conditions were given rhodiola with schisandra chinesis
and ginseng to find that participants had greater focus,
mental speed, and accuracy during stressful conditions.7
Individuals with physical and cognitive deficiencies were
given rhodiola with a combination of vitamins for 12
weeks. Researchers observed a significant improvement in
physical and cognitive complaints, including sleep
disturbance, low motivation, exhaustion, forgetfulness,
etc.8 Rhodiola may also protect against oxidative stress
and mental deficiencies that can come with age-related
cognitive dysfunction.9
Energy: Rhodiola can lessen fatigue that may occur with
chronic stress. One study observed the effects of rhodiola
extract on 56 healthy physicians that were suffering from
fatigue during night shifts. After two weeks of rhodiola
supplementation, the study found a significant
improvement in energy levels among individuals taking
the extract. Researchers suggested rhodiola can decrease
fatigue during stressful conditions.10 Rhodiola was given
to 40 students during an exam period to find that it
significantly improved mental performance, sleep
patterns, motivation to study, physical fitness, and energy
levels.11
As a dietary supplement, adults take 3 capsules daily, or
as directed by a healthcare professional.
The maximum safe dosages of the nutrients in this formula
have not been determined for children, pregnant or
nursing women, or those with severe liver or kidney
disease. As with all supplement regimens, please consult
your physician prior to use.
There are no known adverse reactions with proper
supplementation.
Drug Interactions
There are no known interactions with proper
supplementation.
Store in a cool, dry place, away from direct light. Keep
out of reach of children.
1. Panossian A, Wikman G, Sarris J. Rosenroot (Rhodiola rosea):
traditional use, chemical composition, pharmacology and clinical efficacy.
Phytomedicine. 2010 Jun;17(7):481-493.
2. Perfumi M, Mattioli L. Adaptogenic and central nervous system effects
of single doses of 3% rosavin and 1% salidroside Rhodiola rosea L.
extract in mice. Phytother Res. 2007; 21(1):37-43.
3. Mattioli L, Funari C, Perfumi M. Effects of Rhodiola rosea L. extract
on behavioural and physiological alterations induced by chronic mild
stress in female rats. J Psychopharmacol. 2008 May 30.
4. Maslova LV, Kondrat’ev B, Maslov LN, Lishmanov I. The
cardioprotective and antiadrenergic activity of an extract of Rhodiola
rosea in stress. Eksp Klin Farmakol. 1994; 57(6): 61-63.
5. Maslov LN, Lishmanov IB. Cardioprotective and antiarrhythmic
properties of Rhodiolae roseae preparations. Eksp Kiln Farmakol. 2007
Sep;70(5):59-67.
6. Shen W, Fan WH, Shi HM. Effects of rhodiola on expression of
vascular endothelial cell growth factor and angiogenesis in aortic
atherosclerotic plaque of rabbits. Zhongguo Zhong Xi Yi. 2008
Nov;28(11):1022-1025.
7. Aslanyan G, Amroyan E, Gabrielyan E, Nylander M, et al. Doubleblind, placebo-controlled, randomised study of single dose effects of
ADAPT-232 on cognitive functions. Phytomedicine. 2010 Jun;17(7):494499.
8. Fintelmann V, Gruenwald J. Efficacy and tolerability of a Rhodiola
rosea extract in adults with physical and cognitive deficiencies. Adv Ther.
2007 Jul-Aug;24(4):929-939.
9. Qu ZQ, Zhou Y, Zeng YS, Li Y, Chung P. Pretreatment with Rhodiola
rosea extract reduces cognitive impairment induced by
intracerebroventricular streptozotocin in rats: implication of anti-oxidative
and neuroprotective effects. Biomed Environ Sci. 2009 Aug;22(4):318326.
10. Darbinyan V, Kteyan A, Panossian A, Gabrielian E, et al. Rhodiola
rosea in stress induced fatigue-a double blind cross-over study of a
standardized extract SHR-5 with a repeated low-dose regimen on the
mental performance of healthy physicians during night duty.
Phytomedicine. 2000; 7(5):365-371.
11. Spasov AA, Wikman GK, Mandrikov VB, et al. A double-blind,
placebo-controlled pilot study of the stimulating and adaptogenic effect of
Rhodiola rosea SHR-5 extract on the fatigue of students caused by stress
during an examination period with a repeated low-dose regimen.
Phytomedicine. 2000; 7(2):85-89.
12. Darbinyan V, Aslanyan G, Amroyan E, Gabrielyan E, et al. Clinical
trial of Rhodiola rosea L. extract SHR-5 in the treatment of mild to
moderate depression. Nord J Psychiatry. 2007; 61(5):343-348.
13. Bystritsky A, Kerwin L, Feusner JD. A pilot study of Rhodiola rosea
(Rhodax) for generalized anxiety disorder (GAD). J Altern Complement
Med. 2008; 14(2):175-180.
These statements have not been evaluated by the
Food and Drug Administration. This product is not
intended to diagnose, treat, cure, or prevent any disease.
Manufactured for:
PCCA
9901 S. Wilcrest Dr.
Houston, TX 77099
281.933.6948
Saccharomyces Boulardi is a natural, non-pathogenic
yeast that has been shown to maintain and restore the
healthy ecology of the small and large intestines.
Saccharomyces Boulardi is manufactured using a process
that involves controlled temperature and low vacuum,
eliminating the shock of freeze-drying. The drying
procedure, which does not modify the water content of the
preparation, slows down aging, cell deterioration, and
contamination, leading to increased stability and greater
resistance to gastric acids. The process does not require
lactose, making it perfect for those who are dairy/lactose
intolerant.
Saccharomyces boulardii is a natural, non-pathogenic
yeast that has been shown to maintain and restore the
healthy ecology of the small and large intestines. In a
2010 systematic review and meta-analysis of 31
randomized, placebo-controlled treatment arms in 27 trials
(encompassing 5029 adult study patients), S. boulardii
was found to be significantly efficacious and safe in 84%
of those treatment arms. [1] It has been used safely in
infants and children as well. [2] (Please see “Cautions”)
Extensively researched and published in European and
American peer reviewed journals, Saccharomyces
boulardii has demonstrated several mechanisms of action.
These include 1) secretion of a protease that degrades
bacterial toxins, inhibiting them from binding to the
intestinal brush border, 2) binding of E.coli, Salmonella
ssp, and other bacteria, preventing these bacteria from
adhering to the intestinal epithelium and, possibly,
expelling these pathogens from the body via the stool, [3]
3) interference with enterohemorrhagic Escherichia coliinduced signaling pathways in T84 cell transduction
signals, [4] 4) modulation of the release of polyamines
that restore intestinal mucosal health, possibly by
stimulating the maturation and turnover of enterocytes and
increasing production of disaccharidases such as
glucoamylase, lactase, maltase, and sucrase, 5) stimulation
of immune cells of the intestinal mucosa, inducing
secretion of sIgA, [5] 6) reduction in the secretion of pro-
inflammatory IL-8 by inhibiting production of NFKappaB
and MAPK signaling pathway (also inhibits IL-6 and
TNF-alpha while increasing secretion of antiinflammatory IL-10)[6], 7) hindrance (in vitro) of the
ability of Candida albicans to form filaments and to
adhere and form biofilms, [7] and 8) support for an
increase in fecal short-chain fatty acids, including
butyrate. [8]
•
•
•
Stimulate Immune Response in the Intestinal Mucosa
Enhance Integrity of Mucosa and Enzymatic Activity
of the Intestinal Cells
Neutralize Certain Bacterial Toxins
Saccharomyces Boulardii ................................... 300 mg
(yielding over 3.0 x 109 organism per capsule)
Other ingredients: Cellulose, gelatin (capsule) and
vegetable stearate.
This product contains NO wheat gluten, soy protein,
milk/dairy, corn, artificial coloring, preservatives or
flavoring.
As a dietary supplement, adults take 1 capsule with each
meal (3 times daily) or as directed by your healthcare
professional.
No adverse effects have been reported.
CAUTION: Not for use by infants under six months of
age. Do not use if you have been diagnosed with
immunosuppression or are taking immunosuppressants.
Keep out of reach of children. STORAGE: Keep tightly
closed in a cool, dry place. Does not require refrigeration.
1. McFarland LV. Systematic review and meta-analysis of
Saccharomyces boulardii in adult patients. World J Gastroenterol. 2010
May 14;16(18):2202-22. [PMID: 20458757]
2. Vandenplas Y, et al. Saccharomyces boulardii in childhood. Eur J
Pediatr. 2009 Mar;168(3):253-65. Epub 2008 Dec 19. [PMID: 19096876]
3. Castagliuolo I, et al. Saccharomyces boulardii protease inhibits the
effects of Clostridium diffi cile toxins A and B in human colonic mucosa.
Infect Immun. 1999 Jan;67(1):302-7. [PMID: 9864230]
4. Dahan S, et al. Saccharomyces boulardii interferes with
enterohemorrhagic Escherichia coli-induced signaling pathways in T84
cells. Infect Immun. 2003 Feb;71(2):766-73 [PMID: 12540556]
5. Buts JP, et al. Stimulation of secretory IgA and secretory component of
immunoglobulins in small intestine of rats treated with Saccharomyces
boulardii. Dig Dis Sci. 1990 Feb;35(2):251-6. [PMID: 2302983]
6. Pothoulakis C. Review article: anti-infl ammatory mechanisms of
action of Saccharomyces boulardii. Aliment Pharmacol Ther. 2009 Oct
15;30(8):826-33. Epub 2008 Jul 23. [PMID: 19706150]
7. Krasowska A, et al. The antagonistic effect of Saccharomyces boulardii
on Candida albicans fi lamentation, adhesion and biofi lm formation.
FEMS Yeast Res. 2009 Aug 5. [Epub ahead of print] [PMID: 19732158]
8. Schneider SM, et al. Effects of Saccharomyces boulardii on fecal shortchain fatty acids and microflora in patients on long-term total enteral
nutrition. World J Gastroenterol. 2005 Oct 21;11(39):6165-9. [PMID:
16273644]
9. Saccharomyces boulardii. The Natural Standard Database.
www.naturalstandard.com{accessed 09.13.10}
These statements have not been evaluated by the
Food and Drug Administration. This product is not
intended to diagnose, treat, cure, or prevent any disease.
Manufactured for:
PCCA
9901 S. Wilcrest Dr.
Houston, TX 77099
281.933.6948
Sleep Support contains key ingredients that support a
restful night’s sleep.
Sleep is vital to our mental, emotional and physical
functioning. Research has shown that lack of sleep has a
negative effect on mood, short-term memory, reaction
time, alertness and the immune system. Factors that
interfere with sleep include: stress, anxiety, caffeine
consumption, alcohol consumption, eating late at night,
overstimulation (TV, work, noise), medications
(antidepressants, appetite suppressants and
decongestants), health conditions (arthritis,
hyperthyroidism and indigestion), and sleep apnea.
Alternately, there are many lifestyle habits that can
promote healthy sleep, such as stopping caffeine
consumption after noon, making your bedroom
completely dark and avoiding activities that stimulate the
brain (such as watching TV) before bed. The ingredients
in sleep support provide a broad spectrum of nutrients and
herbs plus the hormone melatonin to assist in falling
asleep, staying asleep and sleeping deeply. Melatonin, a
hormone secreted by the pineal gland, has been shown to
regulate the sleep/wake cycle, assist with sleep onset and
improve sleep quality. Vitamin B6 is necessary for the
production of the neurotransmitter serotonin, the precursor
to melatonin. Valerian, a botanical traditionally used to
support healthy, sleep facilitates the onset of deep sleep.
Passion flower and L-Theanine have been included for
their anti-anxiety and anti-stress properties.
Sleep Support may be a useful dietary supplement for
those who wish to enhance their ability to fall asleep and
sleep soundly.
L-Theanine (from Suntheanine®) ........................ 100 mg
Passion flower aerial extract ............................... 100 mg
(Passiflora incarnata)
(Standardized to 3.5% [3.5 mg] Vitexin)
Valerian root extract ............................................. 50 mg
(Standardized to 0.4% (0.4 mg) Valerenic Acids)
Adults take one (1) capsule before bed time or as directed
by a healthcare professional.
USE ONLY AT BEDTIME. Not for use by children
under 18 years. If pregnant, breastfeeding or using a
prescription drug, consult a healthcare professional. Do
not take this product if you suffer from an autoimmune
disease, depression, diabetes, endocrine disorder, or
thyroid condition. Do not use this product while operating
a motor vehicle or heavy machinery.
Store in a cool, dry place, away from direct light. Keep
out of reach of children.
Bonnet, MH, and DL Arand. 2003. Clinical effects of sleep fragmentation
versus sleep deprivation. Sleep Med Rev. 7(4):297-310.
Donath F, Quispe S, Diefenback K et al. Critical evaluation of the effect
of valerian extract on sleep structure and sleep quality.
Pharmacopsychiatry. 2000;33(2):47-53.
Kimura K, Ozeki M, Juneja L et al. L-Theanine reduces psychological
and physiological stress responses. Biological Psychology. 2007;74:3945.
Ngan A and Conduit R. A double-blind, placebo-controlled investigation
of the effects of Passiflora incarnata (passionflower) herbal tea on
subjective sleep quality. Phytother Res. 2011;25(8):1153-1159.
Sadeghniiat-Haghighi K, Aminian O, Pouryaghoub G et al. Efficacy and
hypnotic effects of melatonin in shift-work nurses: double-blind, placebocontrolled crossover trial. Journal of Circadian Rhythms. 2008;6:10.
Wheatley D. Medicinal plants for insomnia: a review of their
pharmacology, efficacy and tolerability. J Psychopharmacol.
2005;19(4):414-421.
Vitamin B6 (as pyridoxine HCl .............................. 2 mg
Magnesium (as carbonate) .................................... 50 mg
Melatonin ................................................................ 1 mg
These statements have not been evaluated by the
Food and Drug Administration. This product is not
intended to diagnose, treat, cure, or prevent any disease.
Manufactured for:
PCCA
9901 S. Wilcrest Dr.
Houston, TX 77099
281.933.6948
Strontium Citrate capsules provide 200 mg of elemental
strontium in each vegetarian capsule.
Bone health is rapidly becoming an increasingly important
issue. It is well known that the risk of fracture increases
with age and that the number of people over 50 years of
age is a rapidly growing segment of the population. By the
year 2020, half of all Americans will already have or will
develop problems with their bone structure.
Brandi ML. New treatment strategies: ipriflavone, strontium, vitamin D
metabolites and analogs. Am J Med 1993;95:69S-74S.
Meunier PJ, Roux C, Seeman E, et al. The effects of strontium ranelate
on the risk of vertebral fracture in women with postmenopausal
osteoporosis. N Engl J Med 2004;350:459-68.
Neuprez A, Reginster JY. Bone-forming agents in the management of
osteoporosis. Best Pract Res Clin Endocrinol Metab. 2008 Oct;22(5):
869-83
Skoryna SC. Effects of oral supplementation with stable strontium.
Can Med Assoc J 1981;125:703-12.
Verberckmoes SC, De Broe ME, D'Haese PC. Dose-dependent effects
of strontium on osteoblast function and mineralization. Kidney Int
2003;64:534-43
The maintenance of healthy bone structure results from a
balance of bone resorption (by osteoclasts) coupled with
bone formation (from osteoblasts). The trace mineral
strontium supports healthy bone structure by promoting
healthy osteoblast activity while maintaining healthy
osteoclast activity.
Human studies have shown the supplementation with
strontium containing products may help maintain normal
bone structure, including hip bones and vertebrae.
Strontium Citrate may be a useful dietary supplement for
individuals wishing to support normal bone health.
Strontium (from strontium citrate) ...................... 200 mg
Adults take 1 capsule daily with meals or as directed by
your healthcare professional.
No adverse effects have been reported.
Store in a cool, dry place, away from direct light.
Keep out of reach of children.
These statements have not been evaluated by the
Food and Drug Administration. This product is not
intended to diagnose, treat, cure, or prevent any disease.
Manufactured for:
PCCA
9901 S. Wilcrest Dr.
Houston, TX 77099
281.933.6948
Thyroid Support with Zinc is a comprehensive vitamin,
mineral and herbal formula designed to support healthy
functioning of the thyroid gland.
Zinc (as monomethionine from L-OptiZinc®) ....... 10 mg
Selenium (as selenomethionine) ........................ 100 mcg
Copper (as amino acid chelate) ............................... 2 mg
L-Tyrosine .......................................................... 500 mg
Green Tea (Camellia sinensis) leaf extract ........... 60 mg
(Standardized to 98% [58.8 mg] polyphenols)
The thyroid gland produces and secretes thyroid
hormones, mostly T4 (inactive) and small amounts of T3
(active). When needed T4 is typically converted in the
liver, kidney and other tissues to active T3. The primary
action of thyroid hormone is to raise the body’s metabolic
rate — that is, to increase the rate of oxygen consumption
and energy expenditure. Thyroid hormone is also essential
for normal growth and development in children, interacts
with other hormones to modulate carbohydrate, fat and
protein metabolism, and controls other important
biological functions.
Thyroid Support with Zinc provides the amino acid
tyrosine and the mineral iodine (from kelp) — essential
structural components of triiodothyronine (T3). Selenium
is included as an essential cofactor for the enzymes that
convert inactive T4 (thyroxine) into the active T3
(triiodothyronine). Also included are Ayurvedic herbs
traditionally used to support thyroid health, including
Commiphora mukul (Gugulipid®) and Bacopa monniera
(Bacopin®).
Gugulipid (Commiphora mukul) resin extract .... 150 mg
(Standardized to 2.5% [3.75 mg] guggulsterones)
Bacopin (Bacopa monniera) leaf extract............. 100 mg
(Standardized to 20% [20 mg] bacosides A&B)
Ashwagandha (Withania somnifera) root extract 100 mg
(Standardized to 1.5% [1.5mg]
Contains No sugar, salt, dairy, wheat, gluten, preservatives,
artificial colors or flavors.
Adults take two vegetarian capsules at mealtime or as
directed by a healthcare professional.
Please consult with a healthcare professional before taking
Thyroid Support with Zinc if you are pregnant or
breastfeeding, or have hypothyroidism or
hyperthyroidism.
Store in a cool, dry place, away from direct light. Keep
out of reach of children.
Thyroid Support with Zinc may be a useful dietary
supplement for those who wish to support healthy
functioning of the thyroid gland.
Vitamin A (as palmitate)..... .............................. 2,500 IU
Vitamin C (as ascorbic acid) ................................. 30 mg
Vitamin D (as cholecalciferol) ............................. 400 IU
Vitamin B-6 (as pyridoxine HCl) .......................... 15 mg
Folic Acid ..........................................................400 mcg
Iodine (from kelp) ..............................................300 mcg
Magnesium (as oxide, amino acid chelate) ......... 100 mg
These statements have not been evaluated by the
Food and Drug Administration. This product is not
intended to diagnose, treat, cure, or prevent any disease.
Balch, P. and J. Balch. Prescription for Nutritional Healing, 3rd Ed. New
York: Avery; 2000.
Groff, J and S. Gropper. Advanced Nutrition and Human Metabolism,
3rd Ed. Belmont, CA: Wadsworth; 2006.
Jain A and Gupta VB. Chemistry and pharmacological profile of guggul
— a review. Indian Journal of Traditional Knowledge. 2006;5(4):478483.
Kar A, Panda S, Bharti S. Relative efficacy of three medicinal plant
extracts in the alteration of thyroid hormone concentrations in male mice
J Ethnopharmacol. 20002;81(2):281-285.
NIH web site. Masten SA. Guggul and its steroidal constituents: a review
of the toxicological literature. Available at:
http://ntp.niehs.nih.gov/ntp/htdocs/chem_background/exsumpdf/gumgugg
ul.pdf. Accessed 8/2/12.
Manufactured for:
PCCA
9901 S. Wilcrest Dr.
Houston, TX 77099
281.933.6948
Ubiquinol is the reduced (electron-rich) from of
Coenzyme Q10. It is identical to the CoQ10 produced by
the body and is already activated, bypassing the need for
conversion.
Ubiquinol is an integral part of the body’s antioxidant
defense system. Antioxidant nutrients are necessary to
protect the body from the destructive effects of harmful
molecules that cause oxidation. As a lipid soluble
antioxidant it actively eliminates peroxyl radicals,
hydroperoxyl radicals and lipid peroxides in biological
membranes. Ubiquinol also regenerates oxidized vitamin
E, restoring its antioxidant function. Supplementation with
ubiquinol has been shown to increase the resistance of
LDL cholesterol to oxidation in human subjects. Evidence
suggests that oxidative stress contributes to the
development of many common health problems, including
atherosclerosis and diabetes mellitus. Ubiquinol is also a
carrier of electrons in the mitochondrial electron transport
chain that plays a role in ATP synthesis. It is present in
large quantities in tissues with very high metabolic
demands, such as cardiac muscle. Numerous studies have
shown that supplementation with ubiquinol may support
cardiac health.*
Ubiquinol may be a useful dietary supplement for those
who wish to support mitochondrial or cardiovascular
health or enhance antioxidant protection.
Contains No sugar, salt, dairy, yeast, wheat, gluten, corn,
preservatives, artificial colors or flavors.
As a dietary supplement, adults take one (1) softgel
capsule, one (1) to three (3) times daily with meals or as
directed by a health care professional.
Please consult with a healthcare professional before taking
Ubiquinol if you are taking Warfarin (Coumadin) or
antihypertensive drugs
Store in a cool, dry place, away from direct light. Keep
out of reach of children.
Groff, J and S. Gropper. Advanced Nutrition and Human Metabolism,
3rd Ed. Belmont, CA: Wadsworth; 2006.
Langsjoen PH and Langsjoen AM. Supplemental ubiquinol in patients
with advanced congestive heart failure. Biofactors. 2008;32(1-4):119128.
Langsjoen PH and Langsjoen AM. Overview of the use of CoQ10 in
cardiovascular disease. Biofactors. 1999;(9):273-284.
Schmelzer C and Döring F. Micronutrient special issue: Coenzyme Q
(10) requirements for DNA damage prevention. Mutat Res. 2012;733(12):61-68.
Thomas S, Neuzil J, Mohr D et al. Coantioxidants make α-tocopherol and
efficient antioxidant for low density lipoprotein. Am J Clin Nutr. 1995;
62(suppl):1357S-64S.
WebMD web site. Coenzyme Q-10. Accessed 7/28/12.
1 Softgel Capsule Contains:
Ubiquinol CoQH ................................................. 100 mg
(Reduced form of CoQ10)
Other Ingredients: Capsule (gelatin, glycerin, and water),
soybean oil, beeswax, soy lecithin and carob.
Ubiquinol QH™ is manufactured by Kaneka, one of the
world’s leaders in natural pharmaceutical grade CoQ10. It
is produced through a patented process that stabilizes this
reduced form of CoQ10 against oxidation.
These statements have not been evaluated by the
Food and Drug Administration. This product is not
intended to diagnose, treat, cure, or prevent any disease.
Manufactured for:
PCCA
9901 S. Wilcrest Dr.
Houston, TX 77099
281.933.6948
VegiZyme is the most potent, cost-effective, nonprescription, broad spectrum, non-animal-derived
digestive enzyme formula on the market. Each capsule is
packed to the maximum with lipase, proteases, lactase,
and alpha galactosidase. The latter also contains
dipeptidyl peptidase IV. Unlike porcine pancreatin, which
only works in a narrow pH, VegiZyme works in a wide
range of pH.
Pancreatic juice neutralizes stomach acid and contains
enzymes needed to digest foods and properly absorb
nutrients. Amylase, also found in saliva, breaks down
carbohydrates into simple sugar. Lipase works with bile to
dissolve fats into fatty acids. Proteases break down protein
molecules into amino acids, also keeping intestinal
bacteria, protozoa, and yeast in check.
The inability to produce adequate enzymes can result from
pancreatic insufficiency or damage to the brush border
villi. Both are common, especially in older adults.[1] In a
person of any age, many experts believe that inadequate
enzyme production may be a significant culprit in food
allergies/sensitivities. Common post-meal symptoms of
enzyme insufficiency include indigestion, bloating,
cramping, and gas. Other symptoms include weight loss,
as well as frequent loose, odorous stools that float and
look greasy or fatty.
The pancreas is complemented by the intestinal brush
border cells, which produce lactase, peptidase, maltase,
sucrase, alpha galactosidase, glucoamylase, and alkaline
phosphatase. Any damage to the intestinal mucosa, such
as occurs with bacterial overgrowth, can potentially
decrease brush border function.[2]
Lactose, a disaccharide prebiotic/energy source composed
of glucose and galactose, promotes absorption of calcium,
phosphorous, and iron. Approximately 70% of the world’s
population suffers from a generally lifelong insufficiency
of lactase, the enzyme needed to break down lactose.
Malabsorbed lactose causes diarrhea when fluid and
electrolytes are drawn into the lumen by the osmotic load.
Colonic bacteria use unabsorbed lactose to produce
volatile fatty acids and gases, leading to bowel distension,
pain, flatulence, and acidity. Removing dietary lactose,
although effective, can be difficult and may lead to
nutrient deficiencies. Replacing lactase is effective
management.[3,4,5] VegiZyme contains 9,000 FCC
lactase units per capsule, the equivalent of three tablets of
regular LactAid®.
Raffinose, stacchionose, and melibiosc, polysaccharides
commonly found in legumes, are hydrolyzed in the small
intestine by the enzyme, Alpha Galactosidase. In the
absence/deficit of this enzyme, the sugars pass into the
large intestine, where microbes ferment them and produce
gas, bloat, pain, and general discomfort. This condition is
sometimes referred to as Complex Carbohydrate
Intolerance (CCI). Unlike the variety of means used to
treat symptoms of CCI, taking alpha galactosidase itself
prevents their initial occurrence.[6,7]
Cellulase, Hemicellulase, and Xylanase are present to
deconstruct plant cell walls, improving their digestibility.
Phytase breaks down undigestible phytates from grains
and seeds, releasing phosphorous, calcium, inositol, and
other nutrients for absorption. Bromelain and papain, in
addition to peptidase and proteases (which function
optimally within specific pH ranges), offer proteolytic
support. Invertase catalyzes sugar to glucose and fructose.
VegiZyme may be a useful dietary supplement for those
who wish to support healthy digestion of macronutrients
and enhance nutrient absorption.
Protease (pH 2.5-5.0) ...................................... 3025 SAP
Alpha-Galactosidase ..................................... 1,000 GAL
Amyloglucosidase (Glucoamylase)....................... 30 AG
Beta-Glucanase .................................................. 50 BGU
Bromelain (from pineapple) ...................... 1,745,000 PU
Cellulase .......................................................... 5,000 CU
Amylase ....................................................... 12,000 SKB
Lactase .......................................................... 9,000 ALU
Protease (pH 3.0-6.0) ................................ 100,000 HUT
Hemicellulase................................................ 2,000 HCU
Lipase............................................................ 10,000 FIP
Peptidase ....................................................... 1,200 HUT
Invertase.................................................... 1,000 Sumner
Papain (from papaya) ..................................... 33,000 TU
Pectinase ...................................................... 35 Endo PG
Phytase .................................................................... 10 U
Xylanas ...............................................................150 XU
Other Ingredients: Vegetable Capsule (HPMC, water),
microcrystallinecellulose, magnesium stearate.
As a dietary supplement, one or more capsules at the
beginning of or with a meal/snack, or as directed by a
healthcare professional. If necessary, capsules may be
opened and contents sprinkled over food
No adverse effects have been reported.
Caution: Avoid if allergic to pineapple, papaya,
aspergillus, or any other ingredient.
Store in a cool, dry place, away from direct light. Keep
out of reach of children.
1. Detel D, et al. The influence of age on intestinal dipeptidyl peptidase
IV (DPP IV/CD26), disaccharidases, and alkaline phosphatase enzyme
activity in C57BL/6 mice. Exp Aging Res. 2008 Jan-Mar;34(1):49-62
[PMID: 18189167]
2. Zaouche A, et al. Effects of oral Saccharomyces boulardii on bacterial
overgrowth, translocation, and intestinal adaptation after small-bowel
resection in rats. Scand J Gastroenterol. 2000 Feb;35(2):160-5. [PMID:
10720113]
3. Perino A, et al. Lactose intolerance: a non-allergic disorder often
managed by allergologists. Eur Ann Allergy Clin Immunol. 2009
Feb;41(1):3-16 [PMID: 19496347]
4. Gao KP, et al. Effect of lactase preparations in asymptomatic
individuals with lactase deficiency--gastric digestion of lactose and breath
hydrogen analysis. Nagoya J Med Sci. 2002 May;65(1-2):21-8 [PMID
12083287]
5. Sanders SW, et al. Effect of a single dose of lactase on symptoms and
expired hydrogen after lactose challenge inlactose-intolerant subjects.
Clin Pharm. 1992 Jun;11(6):533-8. [PMID: 1534729]
6. Rehms H, Barz W. Degradation of stachyose, raffinose, melibiose, and
sucrose by different tempe-producing Rhizopus fungi. Appl Microbiol
Biotechnol. 1995 Dec;44(1-2):47-52. [PMID: 8579835]
7. Ganiats TG, et al. Does Beano prevent gas? A double-blind crossover
study of oral alpha-galactosidase to treat dietary oligosaccharide
intolerance. J Fam Pract. 1994 Nov;39(5):441-5. [PMID: 7964541]
8. Lettieri JT, Dain B. Effects of beano on the tolerability and
pharmacodynamics of acarbose. Clin Ther. 1998 May - Jun;20(3):497504 [PMID: 9663365]
These statements have not been evaluated by the
Food and Drug Administration. This product is not
intended to diagnose, treat, cure, or prevent any disease.
Manufactured for:
PCCA
9901 S. Wilcrest Dr.
Houston, TX 77099
281.933.6948
Vitamin D contains 5,000 I.U. of natural vitamin D3 per
tablet.
Vitamin D, also known as the “sunshine vitamin,” is an
essential vitamin that plays many important roles in the
proper functioning of the body. Though classified as a
vitamin, vitamin D is actually a key regulatory hormone
for calcium and bone metabolism. Adequate vitamin D
status is essential for ensuring normal calcium absorption
and maintenance of healthy plasma calcium levels.
Besides bone support, vitamin D has many other roles in
the body, including modulation of cell growth,
neuromuscular and immune function and inflammatory
support.
Numerous scientists now feel that supplementation with
vitamin D at levels greater than previously thought
necessary is critical to helping maintain healthy bone
remodeling and healthy vitamin D plasma levels.
Vitamin D 5,000 IU may be a useful dietary supplement
for those individuals wishing to support general health or
whose requirements for vitamin D cannot be met by lower
potency products.
No adverse effects have been reported.
Store in a cool, dry place, away from direct light. Keep
out of reach of children.
Backstrom MC, Maki R, Kuusela AL, Sievanen H, Koivisto AM, Ikonen
RS, Kouri T, Maki M. Randomised controlled trial of vitamin D
supplementation on bone density and biochemical indices in preterm
infants. Arch Dis Child Fetal Neonatal Ed. 1999 May;80(3):F161-6.
Brenner S, Horwitz C. Possible nutrient mediators in psoriasis and
seborrheic dermatitis. II. Nutrient mediators: essential fatty acids;
vitamins A, E and D; vitamins B1, B2, B6, niacin and biotin; vitamin C
selenI.U.m; zinc; iron. World Rev Nutr Diet 1988;55:165-182.
Gillespie WJ, Henry DA, O'Connell DL, Robertson J. Vitamin D and
vitamin D analogues for preventing fractures associated with involutional
and post-menopausal osteoporosis. Cochrane Database Syst Rev.
2000;(2):CD000227. Vitamin D 5,000 I.U.
Recker RR, Davies KM, Dowd RM, Heaney RP. The effect of low-dose
continuous estrogen and progesterone therapy with calcium and vitamin
D on bone in elderly women. A randomized, controlled trial. Ann Intern
Med. 1999 Jun 1;130(11):897-904.
Reid IR. The roles of calcium and vitamin D in the prevention of
osteoporosis. Endocrinol Metab Clin North Am. 1998 Jun;27(2):389-98.
Stallings VA. Calcium and bone health in children: a review. Am J Ther.
1997 Jul-Aug;4(7-8):259-73.
Swaminathan R. Nutritional factors in osteoporosis. Int J Clin Pract. 1999
Oct-Nov;53(7):540-8. 22.
Vitamin D-3 .................................................... 5,000 I.U.
(as cholecalciferol)
Other Ingredients: Softgel (gelatin, glycerin and water),
virgin olive oil.
Contains No sugar, salt, yeast, wheat, dairy, gluten, corn,
soy, preservatives, artificial colors or flavors.
As a dietary supplement, adults take one (1) softgel daily
with meals, or as directed by a healthcare professional.
These statements have not been evaluated by the
Food and Drug Administration. This product is not
intended to diagnose, treat, cure, or prevent any disease.
Manufactured for:
PCCA
9901 S. Wilcrest Dr.
Houston, TX 77099
281.933.6948
Vitex supplies 400 mg of Agnus castus standardized herb
in each vegetarian capsule.
Agnus castus, also known as vitex or chastberry, is a
traditional herb native to Central Asia and the
Mediterranean region. It has been traditionally used to
support healthy reproductive function in women.
Premenstrual tension (PMT), also called premenstrual
syndrome, is a condition that affects many menstruating
women one to two weeks before they begin menstruation.
Symptoms may include abdominal bloating, cramping,
breast tenderness and swelling, fatigue, irritability,
anxiety, headache, and more. Research suggests that
Agnus castus may play an important role in supporting a
woman’s natural response to PMT.
Atmaca M, Kumru S, Tezcan E. Fluoxetine versus Vitex agnus castus
extract in the treatment of premenstrual dysphoric disorder. Hum
Psychopharmacol Clin Exp 2003;18:191–195.
Lauritzen CH, Reuter HD, Repges R, et al. Treatment of premenstrual
tension syndrome with Vitex agnus castus: Controlled-double blind
versus pyridoxine. Phytomedicine 1997;4:183-9.
Meier B, Berger D, Hoberg E, et al. Pharmacological activities of Vitex
agnuscastus extracts in vitro. Phytomedicine 2000;7:373-81.
Prilepskaya VN, Ledina AV, Tagiyeva AV, Revazova FS. Vitex agnus
castus: Successful treatment of moderate to severe premenstrual
syndrome. Maturitas 2006;55 Suppl 1:S55-63.
Turner S, Mills S. A double-blind clinical trial on a herbal remedy for
premenstrual syndrome: a case study. Complement Ther Med 1993;
1:73-77.
Vitex may be a useful dietary adjunct for individuals
wishing to supplement with this herb.
Agnus castus(standardized) ............................... 400 mg
Adults take 1 capsule daily or as directed by physician.
No adverse effects have been reported.
Store in a cool, dry place, away from direct light.
Keep out of reach of children.
These statements have not been evaluated by the
Food and Drug Administration. This product is not
intended to diagnose, treat, cure, or prevent any disease.
Manufactured for:
PCCA
9901 S. Wilcrest Dr.
Houston, TX 77099
281.933.6948
Zinc Liquid supplies 13.5 mg of elemental zinc from zinc
sulfate heptahydrate in purified water.
Zinc Liquid may be a useful dietary adjunct for
individuals wishing to supplement their diet with zinc.
Zinc is an essential trace element required for the activity
of over 300 enzymes and is involved in most major
metabolic pathways. Zinc participates not only in catalytic
processes, but also in the structure and stability of some
regulatory proteins.
Zinc (as Zinc Sulfate Heptahydrate) .................. 13.5 mg
Other Ingredients: Water, citric acid and potassium
sorbate
General signs of human zinc deficiency indicate that zinc
has important functions in maintaining immune function,
reproduction, healthy skin, and growth.
Adults take 1-2 teaspoons daily with meals or as directed
by physician.
Numerous studies support the fundamental role of zinc for
normal immune response in humans. Immune cells must
be able to rapidly divide in order to respond to daily
challenges. Like all rapidly dividing cells, immune cells
depend on adequate amounts of dietary zinc.
No adverse effects have been reported.
Store in a cool, dry place, away from direct light.
Keep out of reach of children.
As a cofactor of the antioxidant enzyme superoxide
dismutase (SOD), zinc can be considered an antioxidant
nutrient. Zinc supplementation has been shown to increase
the antioxidant activity of SOD, and provide increased
free radical protection. Zinc deficiency is associated with
increased oxidative damage.
Absorption of toxic heavy metals, especially cadmium and
lead, is lower in individuals with high zinc status
compared to those with low zinc status.
The body pool of readily available zinc appears to be
small, which renders the body susceptible to deficiency
and therefore dependent on a steady dietary supply of
bioavailable zinc. While typical zinc intakes in U.S. adults
are between 10 and 15 mg per day, which approach the
RDA, intakes in the elderly are often low. Pregnant
women are also at risk for zinc deficiency, since they have
a higher requirement for this trace element.
Chen, MD, Song, YM, Lin, PY. Zinc may be a mediator of leptin
production in humans. Life Sci 2000;66:2143-9.
DiSilvestro, RA. Zinc in relation to diabetes and oxidative disease. J Nutr
2000;130:1509S-11S.
Frederickson, CJ, Suh, SW, Silva, D, Thompson, RB. Importance of zinc
in the central nervous system: the zinc-containing neuron. J Nutr
2000;130:1471S-83S.
Huang, X, Cuajungco, MP, Atwood, CS, Moir, RD, Tanzi, RE, Bush, AI.
Alzheimer's disease, beta-amyloid protein and zinc. J Nutr
2000;130:1488S-92S.
Kohn, S, Kohn, D, Schiller, D. Effect of zinc supplementation on
epidermal Langerhans' cells of elderly patients with decubital ulcers. J
Dermatol 2000;27:258-63.
MacDonald, RS. The role of zinc in growth and cell proliferation. J Nutr
2000;130:1500S-8S.
McCall, KA, Huang, C, Fierke, CA. Function and mechanism of zinc
metalloenzymes. J Nutr 2000;130:1437S-46S.
Meynadier, J. Efficacy and safety study of two zinc gluconate regimens in
the treatment of inflammatory acne. Eur J Dermatol 2000;10:269-73.
Frequently, vegetarians and chronically depressed
individuals have been found to have low zinc status.
These statements have not been evaluated by the
Food and Drug Administration. This product is not
intended to diagnose, treat, cure, or prevent any disease.
Manufactured for:
PCCA
9901 S. Wilcrest Dr.
Houston, TX 77099
281.933.6948