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Which of the following is/are true regarding Ulcerative
Colitis (UC)?
A. Females are affected more then males.
B. Surgery is curative.
C. The most consistent risk factor is family history.
D. 75% of patients with Crohn’s will be have a positive pANCA antibody, distinguishing it from UC.
E. Smokers are at a higher risk for developing UC.
Which of the following is/are true regarding Ulcerative
Colitis (UC)?
A. Females are affected more then males. (FALSE approximately equal in both genders)
B. Surgery is curative. (TRUE)
C. The most consistent risk factor is family history. (TRUE)
D. 75% of patients with Crohn’s will be have a positive pANCA antibody, distinguishing it from UC. (FALSE - UC
patients are p-ANCA Ab +)
E. Smokers are at a higher risk for developing UC. (FALSE Active smokers are at a lower risk)
Which of the following is a feature of UC, Crohn’s, or both?
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segmental disease (skip lesions)
transmural involvement
granulomas
cancer risk
small bowel involvement
“cobblestoning”
rectal disease
bleeding per rectum
diarrhea
infiltration of PMNs into the crypts of Lieberkuhn forming
crypt abscesses
Which of the following is a feature of UC, Crohn’s, or both?
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segmental disease (skip lesions) (Crohn’s)
transmural involvement (Crohn’s)
granulomas (Crohn’s)
cancer risk (both)
small bowel involvement (Crohn’s)
“cobblestoning” (Crohn’s)
rectal disease (both)
bleeding per rectum (both)
diarrhea (both)
infiltration of PMNs into the crypts of Lieberkuhn forming
crypt abscesses (UC)
Which of the following is/are TRUE about the pathologic
features of UC?
A. UC always involves the rectum.
B. UC patients may have pancolitis but it usually stops at the
hepatic flexure.
C. Strictures are usually caused by malignant transformation
of the muscularis mucosa.
D. UC involves only mucosa and submucosal layers.
E. UC may progress to toxic megacolon with risk of necrosis
and perforation.
Which of the following is/are TRUE about the pathologic
features of UC?
A. UC always involves the rectum. (TRUE)
B. UC patients may have pancolitis but it usually stops at the
hepatic flexure. (FALSE, splenic flexure)
C. Strictures are usually caused by malignant transformation
of the muscularis mucosa. (FALSE, benign strictures)
D. UC involves only mucosa and submucosal layers.
(TRUE)
E. UC may progress to toxic megacolon with risk of necrosis
and perforation. (TRUE)
Name some of the extraintestinal manifestations of IBD that
commonly occur in UC.
Name some of the extraintestinal manifestations of IBD that
commonly occur in UC.
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ankylosing spondylitis
primary sclerosing cholangitis (more common in UC)
erythema nodosum (more common in Crohn’s)
pyoderma gangrenosum (more common in UC)
uveitis
sacroiliitis
Which of the following is/are true?
A. The test of choice for diagnosis of UC is a barium enema.
B. All patients with newly diagnosed UC should have an UGI
series with small bowel follow through.
C. The risk of carcinoma is directly related to the duration of
disease and is 50% 40yrs after presentation of pancolitis
D. Colonoscopic surveillance should be started at least 10
years after diagnosis
Which of the following is/are true?
A. The test of choice for diagnosis of UC is a barium enema.
(FALSE, colonoscopy)
B. All patients with newly diagnosed UC should have an UGI
series with small bowel follow through. (TRUE, to rule
out Crohn’s)
C. The risk of carcinoma is directly related to the duration of
disease and is 50% 40yrs after presentation of pancolitis.
(FALSE, risk after 40yrs is 75%)
D. Colonoscopic surveillance should be started at least 10
years after diagnosis (TRUE)
Name some indications for surgical intervention in UC.
Name some indications for surgical intervention in UC.
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Intractability
Dysplasia-Carcinoma
Massive Colonic Bleeding
Toxic Megacolon
Match the following operations with ideal candidate:
A. > 65 years old and/or
decreased fecal
continence
B. < 65 and proctitis
w/rectal dysplasia
C. < 65, no rectal
dysplasia, but high
operative risk
D. < 65, no rectal
dysplasia, and low
operative risk
1. Ileal pouch
anastomoses + anal
mucosectomy
2. Total abdominal
colectomy w/ileal
rectal anastomosis
3. Total
proctocolectomy
w/ileostomy
4. IPAA w/stapled
anastomosis +
diverting ileostomy
Match the following operations with ideal candidate:
A. > 65 years old and/or
decreased fecal
continence
B. < 65 and proctitis
w/rectal dysplasia
C. < 65, no rectal
dysplasia, but high
operative risk
D. < 65, no rectal
dysplasia, and low
operative risk
1. Ileal pouch
anastomoses + anal
mucosectomy
2. Total abdominal
colectomy w/ileal
rectal anastomosis
3. Total
proctocolectomy
w/ileostomy
4. IPAA w/stapled
anastomosis +
diverting ileostomy
Which of the following is/are TRUE regarding post-op
complications in the pouch procedure (restorative
proctocolectomy)?
A. Mechanical bowel obstruction often occurs secondary to
dietary indiscretions w/high roughage intake.
B. Pouchitis occurs in up to 50% of patients.
C. Ceftriaxone is the antibiotic of choice used to treat
pouchitis.
D. Anal strictures less then 10mm should be dilated.
E. Although complication rates are high with the ileal pouchanal anastomoses procedure, patient satisfaction is also
very high.
Which of the following is/are TRUE regarding post-op
complications in the pouch procedure (restorative
proctocolectomy)?
A. Mechanical bowel obstruction often occurs secondary to
dietary indiscretions w/high roughage intake. (TRUE)
B. Pouchitis occurs in up to 50% of patients. (TRUE)
C. Ceftriaxone is the antibiotic of choice used to treat
pouchitis. (FALSE, flagyl is preferred)
D. Anal strictures less then 10mm should be dilated. (FALSE,
less then 5mm)
E. Although complication rates are high with the ileal pouchanal anastomoses procedure, patient satisfaction is also
very high. (TRUE)