Download Powerpoint - Blood Journal

Survey
yes no Was this document useful for you?
   Thank you for your participation!

* Your assessment is very important for improving the workof artificial intelligence, which forms the content of this project

Document related concepts

Syncope (medicine) wikipedia , lookup

Haemodynamic response wikipedia , lookup

Transcript
HIV-1 incorporates ABO histo-blood group antigens that
sensitize virions to complement-mediated inactivation
by Stuart J. D. Neil, Áine McKnight, Kenth Gustafsson, and Robin A. Weiss
Blood
Volume 105(12):4693-4699
June 15, 2005
©2005 by American Society of Hematology
Expression of ABO transferases in cells producing HIV-1 particles leads to incorporation of ABO
antigens into viral envelopes.
Stuart J. D. Neil et al. Blood 2005;105:4693-4699
©2005 by American Society of Hematology
Serum sensitivity of HIV-1 vectors encoding eGFP and pseudotyped with the HIV-1 envelope
HXB2 produced from cells cotransfected with ABO expression vectors.
Stuart J. D. Neil et al. Blood 2005;105:4693-4699
©2005 by American Society of Hematology
Passive acquisition of ABO antigens from human serum by PBMCs. PBMCs isolated from O, A,
or B donors were cultured in 10% human serum from individuals of blood group A or B. The
cells were stained for blood group antigen expression using the H-specific lect...
Stuart J. D. Neil et al. Blood 2005;105:4693-4699
©2005 by American Society of Hematology
Serum sensitivity of HIV-1 propagated in PBMCs from ABO-defined donors.
Stuart J. D. Neil et al. Blood 2005;105:4693-4699
©2005 by American Society of Hematology
Purified IgM confers ABO serum sensitivity to virions.
Stuart J. D. Neil et al. Blood 2005;105:4693-4699
©2005 by American Society of Hematology