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上海交通大学医学院 教 案 第 课程名称:Idiopathic Facial Palsy (Bell Palsy) 肖勤 教师姓名 职称 副主任 教研室 2007 年 神经病学 9月 教学时数 21 日 0.5 授课题目 Idiopathic Facial Palsy (Bell Palsy) 教学对象 临床医学系 04 级英文班 授课地点 瑞金科教大厦 309 室 教学方式 课堂 本课的重点、难点: 1. 2. 3. 4. 5. 6. 7. 8. 次课 Anatomy of facial nerve Clinical manifestations of facial palsy Bell phenomenon Ramsey Hunt syndrome Difference between peripheral and central facial palsy Diagnosis of facial palsy Differential diagnosis of facial palsy Treatment of facial palsy 本次课应用的教具: POWERPOINT 1. 主要教学内容: (可另附页) Anatomy Pathophysiology •Bell palsy is thought to be caused by edema and ischemia resulting in compression of the facial nerve in its course through the bony canal. In the past, cold exposure were considered the only triggers. However, most authors now believe that the herpes simplex virus (HSV) is the most likely cause. Epidemiology Clinical manifestations •Symptoms: –Acute onset of unilateral upper and lower facial paralysis. The paralysis must include the forehead and lower aspect of the face. - inability to close the eye or to smile on the affected side. - increased saliva on the side of the paralysis. If the paralysis involves only the lower portion of the face, a central cause should be suspected. –Posterior auricular pain –Decreased or increased tearing –Hyperacusis –Taste disturbances Physical Examination: •flattening of the forehead and nasolabial fold on the affected side. •When the patient is asked to raise the eyebrows, the affected side will remain flat. •When the patient is asked to smile, the face becomes distorted and lateralizes to the side opposite the palsy. •The patient is not able to close the eye completely on the affected side. On attempted eye closure, the eye rolls upward and inward on the affected side. This is known as Bell phenomenon. Ramsey Hunt syndrome •Ramsey Hunt syndrome is similar to Bell‘s palsy. The virus that causes the syndrome has been identified as varicella zoster virus (VZV), a strain of the Herpes virus. •In addition to the "classic" symptoms of Bells palsy, Hunt syndrome is associated with some additional symptoms that help differentiate it. 1. pain: often in or behind the ear. 2.vertigo: 3. hearing loss: can also affect the auditory nerve, resulting in hearing deficit. This should not occur with Bells palsy. 4. blisters in the ear 5. Swollen and tender lymph nodes near the affected area Differential Diagnosis Guillain-Barre syndrome Meningitis middle ear or mastoid infections cerebellopontine angle tumors Work-up nerve conduction testing and EMG Treatment •The most widely accepted treatment is corticosteroids. •Since HSV is widely accepted as the likely etiologic agent, acyclovir has also been used. The dose of acyclovir is 400 mg orally 5 times per day. •VitB1、VitB12 Eye care: •Facial muscle exercises 本 次 课 小 结 要 点 Anatomy Pathophysiology Bell palsy is thought to be caused by edema and ischemia resulting in compression of the facial nerve in its course through the bony canal. cold exposure and herpes simplex virus were considered as the triggers. Epidemiology Clinical manifestations Symptoms:Acute onset of unilateral upper and lower facial paralysis. The paralysis must include the forehead and lower aspect of the face. If the paralysis involves only the lower portion of the face, a central cause should be suspected. Posterior auricular pain, Decreased or increased tearing, Hyperacusis, and Taste disturbances Physical Examination: •flattening of the forehead and nasolabial fold on the affected side. When the patient is asked to raise the eyebrows, the affected side will remain flat. When the patient is asked to smile, the face becomes distorted and lateralizes to the side opposite the palsy. •The patient is not able to close the eye completely on the affected side. On attempted eye closure, the eye rolls upward and inward on the affected side. This is known as Bell phenomenon. Ramsey Hunt syndrome •Ramsey Hunt syndrome is similar to Bell‘s palsy. The virus that causes the syndrome has been identified as varicella zoster virus (VZV), a strain of the Herpes virus. •In addition to the "classic" symptoms of Bells palsy, Hunt syndrome is associated with some additional symptoms that help differentiate it. pain: often in or behind the ear,vertigo: hearing loss(This should not occur with Bells palsy), blisters in the ear,Swollen and tender lymph nodes near the affected area Differential Diagnosis: Guillain-Barre syndrome, Meningitis, middle ear or mastoid infections, cerebellopontine angle tumors Work-up nerve conduction testing and EMG •Treatment: corticosteroids, acyclovir, VitB1 、 VitB12, Eye care, Facial muscle exercises. 本 次 课 复 习 思 考 题 下 次 课 预 习 要 点 1. 2. 3. 4. 5. 6. 7. 8. Anatomy of facial nerve Clinical manifestations of Bell palsy Ramsey Hunt syndrome Diagnosis of Bell palsy Differential Diagnosis of Bell palsy Treatment of Bell palsy Difference between peripheral and central facial palsy. Bell phenomenon.