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Reproduction Asexual or Sexual? What are we learning? SB2 c. Using Mendel’s laws, explain the role of meiosis in reproductive variability. SB2 e. Compare the advantages of sexual reproduction and asexual reproduction in different situations. Asexual Reproduction Binary fission – when one cell splits into two cells. ◦ DNA replicates during interphase ◦ In Eukaryotic cells the nucleus divides during during mitosis ◦ The cell divides during cytokinesis Mitosis – the division of the nucleus Prophase – DNA becomes visible and is called chromosomes, the nuclear envelope dissolves Metaphase – the chromosomes meet in the middle of the cell Anaphase – the sister chromosomes split and move towards the poles Telophase – the chromosomes unwind, and the nuclear membrane reforms Other uses for Cell division Used to repair tissues For growth. Advantages and Disadvantage of Asexual Reproduction Advantages ◦ Only needs one organism to reproduce ◦ Make lots of individuals quickly ◦ Are identical to parents (keeps the good adaptations that helps survival) Disadvantages ◦ Does not allow for mutations ◦ Can not adapt to the changes in the environment Sexual Reproduction When DNA is exchanged between two organisms Two ways to do this ◦ Conjugation - the exchange of genetic material ◦ Exchange of sex cells Exchange of sex cells In higher plants and animals ◦ Female – eggs ◦ Male – sperm In lower organism ◦ + and – are used to denote sex cells How are sex cells made? Through the process of meiosis ◦ The process make haploid (n) cells (gametes) ▪ Females – 1 cell is the result (the other three are called polar bodies, they are not used for reproduction) ▪ Males – 4 cells are produced Haploid? Diploid? Contains only a single set of chromosomes or single set of genes. ◦ Remember you get one set of genes from your mother the other set from your father. Diploid-contains both sets of chromosomes. Okay, so what are the stages of Meiosis? Meiosis I ◦ Prophase I ◦ Metaphase I ◦ Anaphase I ◦ Telophase I Meiosis II ◦ Prophase II ◦ Metaphase II ◦ Anaphase II ◦ Telophase II Prophase I Each chromosome pairs with its corresponding homologous chromosome to form a tetrad. During prophase I homologous chromosomes may cross over and exchange portions of their chromatids. This process is called crossing over. What is a homologous chromosome? Two chromosomes that make up a matched pair in a diploid cell. One homologous chromosome is inherited from the organism’s mother, the other from the organism’s father. What is a tetrad? A paired set of homologous chromosomes, each composed of two sister chromatids. Metaphase I Spindle fibers attach to the chromosomes and tetrads line up in the center of the cell. Anaphase I The fibers pull the homologous chromosomes toward opposite ends of the cell. Telophase I Nuclear membranes form. The cell separates into two haploid cells. Cytokinesis I Meiosis I results in two haploid (N) daughter cells, each with half the number of chromosomes as the original cell. Prophase II The DNA coils back up around the proteins forming chromosomes. The nuclear membrane dissolves The spindle fibers reform Metaphase II The chromosome line up in a similar way to the metaphase stage of mitosis. Anaphase II The sister chromatids separate and move toward opposite ends of the cell. Telophase II Meiosis II results in four genetically different haploid (N) cells. Advantages and Disadvantages of Sexual Reproduction Advantages ◦ Organism can adapt to changes in the environment ◦ Increase variability in the gene pool Disadvantages ◦ Takes two ◦ Takes more time ◦ Typically less offspring Accidents that can occur during Meiosis Nondisjunction – Members of a chromosome pair fail to separate during anaphase. This results in diploid gametes. Crossing over, that sometimes occur during Prophase I, can cause this. Examples: Trisomy 21(Down’s syndrome) and Klinefelter syndrome. What alterations of chromosome structure (mutations) could lead to birth defects and cancer? Deletion- When a fragment of a chromosome is lost. Duplication- When a fragment from one chromosome joins to a homologous chromosome. Inversion- When a fragment reattaches to the original chromosome but in the reverse direction. Translocation- the attachment of a chromosomal fragment to a nonhomologous chromosome. Quiz: 1. Name 2 ways in which meiosis differ from mitosis? ___________________________________________________ ___________________________________________________ ___________________________________________________ 2.What is a gamete? ___________________________________________________ ___________________________________________________ 3.What does haploid mean? ___________________________________________________ ___________________________________________________ 4.If a human skin cell contains 46 chromosomes, how many chromosomes would a human sperm cell contain? ___________________________________________________ ___________________________________________________ ___________________________________________________ 5.If a human skin cell contained 46 chromosomes, how many chromosomes would a human liver cell contain? ___________________________________________________ ___________________________________________________ ___________________________________________________ 6. What types of accidents can occur in Meiosis? ___________________________________________________ ___________________________________________________ 7.What is crossing over? When does it occur? ___________________________________________________ ___________________________________________________ ___________________________________________________ 8. Name and describe one alteration ___________________________________________________ of chromosome structure. ___________________________________________________